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Electromagnetic irradiation exposure and its bioindication–An overview

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Journal of Environmental Sciences 2011年第9期23卷 1409-1414页

作者： Osmo Hnninen Paavo Huttunen reijo Ekman Department of Physiology Kuopio CampusUniversity of Eastern Finland Department of Electrical and Information Engineering Laboratory of Optoelectronics and Measurement Technology Degree Program in Electronics Radio and EMC LaboratoryTurku University of Applied Sciences

Man made electromagnetic irradiation and fields cover now the globe due to the recent extensive propagation of mobile *** increased load affects animals and also *** birds have been *** are also *** are good bioindicators as epidemiological methods are *** can also report symptoms which cannot be directly measured with presently available *** nonionizing irradiation can as the ionizing one break the DNA,damage proteins,even increase the blood brain barrier permeability,disturb the night rest,cause fatigue and hormonal *** increase of the tumours of human head has been described in correlation with the long term mobile phone use and on that side more *** regulations covering mobile telephony are already about two decades old and need *** multitude of irradiation and the interaction of the different wavelength exposures,i.e.,frequency sensitivity is poorly known at *** should not forget the comparative studies of different species especially those which rely in their lives on electromagnetic orientation *** countries have issued warnings on the exposures of *** producers of mobile technology have recently warned the users not to keep those devices in active stage in skin contact.

关键词： nonionizing radiation electromagnetic fields their sensing animals humans symptoms oxidative stress DNA breaks tumours

Stem cell therapy for Parkinson’s disease: safety and modeling

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Neural Regeneration Research 2020年第1期15卷 36-40页

作者： Theo Stoddard-Bennett Renee reijo Pera Department of Cell Biology and Neurosciences Montana State UniversityBozemanMTUSA Department of Chemistry and Biochemistry Montana State UniversityBozemanMTUSA

For decades,clinicians have developed medications and therapies to alleviate the symptoms of Parkinson’s disease,but no treatment currently can slow or even stop the progression of this localized ***,sparked by the genetic revolution,stem cell reprogramming research and the advancing capabilities of personalization in medicine enable forward-thinking to unprecedented patient-specific modeling and cell therapies for Parkinson’s disease using induced pluripotent stem cells(iPSCs).In addition to modeling Parkinson’s disease more accurately than chemically-induced animal models,patient-specific stem cell lines can be created,elucidating the effects of genetic susceptibility and sub-populations’differing responses to in vitro *** cell therapy with iPSC lines provides ethical advantages because these stem cell lines do not require the sacrifice of human zygotes and genetically-specific drug trails can be tested in vitro without lasting damage to *** hopes of finally slowing the progression of Parkinson’s disease or re-establishing function,iPSC lines can ultimately be corrected with gene therapy and used as cell sources for neural transplantation for Parkinson’s *** relatively localized neural degeneration,similar to spinal column injury,Parkinson’s disease presents a better candidacy for cell therapy when compared to other diffuse degeneration found in Alzheimer’s or Huntington’s *** implantation of pluripotent cells poses the risk of an innate immune response and ***,therefore,must be taken to ensure cell line quality before *** cell quality can be quantified using a number of assays,a yielding a high percentage of therapeutically relevant dopaminergic neurons,minimal de novo genetic mutations,and standard chromosomal structure is of the utmost *** techniques focus on iPSCs because they can be matched with donors using human leukocyte antig

关键词： alpha synuclein animal model cell therapy dopaminergic neurons induced pluripotent stem cells neurodegeneration Parksinson’s disease stem cells

Tackling boundaries of CCS in market deployment of second-generation oxy-fuel technology

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Clean Energy 2018年第1期2卷 72-81页

作者： Kalle Nuortimo Timo Eriksson reijo Kuivalainen Janne Härkönen Harri Haapasalo Timo Hyppänen Sumitomo SHI FW Energia Oy P.O.Box 201 FI-78201 VarkausFinland Sumitomo SHI FW Energia Oy P.O.Box 7FI-02130 EspooFinland Industrial Engineering and Management University of OuluP.O.Box 4610FI-90014Finland LUT School of Energy Systems PL 2053851 LappeenrantaFinland

This article discusses the market potential estimation results at different stages of second-generation oxy-fuel technology for carbon capture and storage,where oxygen content is increased in order to increase efficiency and product life *** article highlights the challenges to commercializing an energy technology with long development lead *** related to external market environment,regulations and market price for carbon dioxide(CO_(2))also need to be *** study is based on a second-generation oxy-CFB technology evaluation,SWOT analysis and product life-cycle *** commercialization of second-generation oxy-fuel technology,estimated as a basis of oxy-CFB technology,is largely found to be dependent on technical,sociological and economical aspects related to the energy market *** CO_(2) price in European Union(EU)emissions trading is currently below 10€/ton,which does not favour investment in ***_(2) storage also faces public opposition and EU directive *** CO_(2) price needs to be in the range of 30€/ton by 2030,the estimated time of *** development or subsidies would also be required for the second-generation oxy-CFB power production concept to become *** is one of the critical factors in market deployment as the price development is influenced by several external factors,including the EU’s environmental policy,politics and public acceptance.

关键词： Second generation oxyfuel technology market deployment CFB technology tackling boundary of CCS

Low-FODMAP vs regular rye bread in irritable bowel syndrome:Randomized SmartPill~ study

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World Journal of Gastroenterology 2018年第11期24卷 1259-1268页

作者： Laura Pirkola reijo Laatikainen Jussi Loponen Sanna-Maria Hongisto Markku Hillila Anu Nuora Baoru Yang Kaisa M Linderborg Riitta Freese Division of Nutrition Department of Food and Environmental SciencesUniversity of HelsinkiHelsinki FI-00790Finland Fazer Group/Fazer Bakeries Ltd Vantaa FI-01230Finland Medical Faculty PharmacologyMedical Nutrition PhysiologyUniversity of HelsinkiHelsinki FI-00290Finland Clinic of Gastroenterology University of Helsinki and Helsinki UniversityHospital JorviEspoo FI-02740Finland Food Chemistry and Food Development Department of BiochemistryUniversity of TurkuTurku FI-20014Finland

AIM To compare the effects of regular vs low-FODMAP rye bread on irritable bowel syndrome(IBS) symptoms and to study gastrointestinal conditions with Smart Pill?.METHODS Our aim was to evaluate if rye bread low in FODMAPs would cause reduced hydrogen excretion,lower intraluminal pressure,higher colonic p H,different transit times,and fewer IBS symptoms than regular rye *** study was a randomized,double-blind,controlled cross-over meal *** IBS patients(n = 7) ate study breads at three consecutive meals during one *** diet was similar for both study periods except for the FODMAP content of the bread consumed during the study *** p H,transit time,and pressure were measured by Smart Pill,an indigestible motility *** Hydrogen excretion(a marker of colonic fermentation) expressed as area under the curve(AUC)(0-630 min) was [median(range)] 6300(1785-10800) ppm?min for low-FODMAP rye bread and 10 635(4215-13080) ppm?min for regular bread(P = 0.028).Mean scores of gastrointestinal symptoms showed no statistically significant differences but suggested less flatulence after low-FODMAP bread consumption(P = 0.063).Intraluminal pressure correlated significantly with total symptom score after regular rye bread(ρ = 0.786,P = 0.036) and nearly significantly after lowFODMAP bread consumption(ρ = 0.75,P = 0.052).We found no differences in p H,pressure,or transit times between the *** residence of Smart Pill was slower than *** Pill left the stomach in less than 5 h only during one measurement(out of 14 measurements in total) and therefore did not follow on par with the rye bread *** Low-FODMAP rye bread reduced colonic fermentation vs regular rye *** difference was found in median values of intraluminal conditions of the gastrointestinal tract.

关键词： Colonic pressure FODMAP Irritable bowel syndrome Rye Wireless motility capsule Symptom severity

环腺苷一磷酸对人Ⅰ型17β羟类固醇脱氢酶在绒癌细胞系中表达的调节作用

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实验生物学报 1997年第1期30卷 99-108页

作者：朴允尚 Hellevi Peltoketo Eloisa JantusLewintre reijo Vihko 天津市计划生育研究所芬兰Oulu大学生物中心及临床化学系 oulu90220

由HSD17B1基因编码的人Ⅰ型17β-羟类固醇脱氢酶(17β-hydroxysteroid dehydrogenasetype 1,简称Ⅰ型17HSD)催化雌酮与雌二醇之间的转化。本文研究环腺苷一磷酸简称(cAM-P)对该酶在培养的绒癌细胞系(JAR和JEG-3)中表达的调节作用。用8-b... 详细信息

由HSD17B1基因编码的人Ⅰ型17β-羟类固醇脱氢酶(17β-hydroxysteroid dehydrogenasetype 1,简称Ⅰ型17HSD)催化雌酮与雌二醇之间的转化。本文研究环腺苷一磷酸简称(cAM-P)对该酶在培养的绒癌细胞系(JAR和JEG-3)中表达的调节作用。用8-bromo-cAMP处理两种绒癌细胞后,观察到在伴随1.3 kbⅠ型17 HSDmRNA表达的同时,Ⅰ型17 HSD蛋白浓度也显著上升。标记基因分析表明,cAMP可诱导HSD 17 B1基因启动子在JAR和JEG-3细胞系中的转录活性,参与调节这一诱导作用的区域位于HSD 17 B1基因编码区上游-659至-550处。凝胶阻滞实验显示这一区域可同JAR、JEG-3、T-47 D和HeLa细胞核抽提物形成特异的DNA-蛋白复合物。本结果首次证实cAMP激活HSD 17 B1基因启动子在绒癌细胞中的转录。

关键词：环腺苷一磷酸羟类固醇脱氢酶绒癌癌细胞

伊朗Markazi省姬蜂科昆虫种类(膜翅目:姬蜂总科)(英文)

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武夷科学 2014年第1期30卷 83-91页

作者： Hassan GHAHARI reijo JUSSILA Neveen S.GADALLAH Department of Plant Protection Shahre Rey BranchIslamic Azad University Zoological Museum Section of Biodiversity and Environmental SciencesDepartment of BiologyFI-20014 University of Turku Entomology Department Faculty of ScienceCairo University

本文调查鉴定了伊朗Markazi省的姬蜂科昆虫种类4亚科13属15种,其中Glypta cylindrator(Fabricius)和Ichneumon terminatorius Gravenhorst为伊朗分布新纪录。

关键词：膜翅目姬蜂科区系 Markazi省伊朗

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北欧国家的健康政策和健康规划

中国初级卫生保健 1992年第6期 41-43页

作者： reijo Salmela 李雅杰刘英乔振宽芬兰坦派勒大学公共卫生系

80年代初,欧洲国家第一次采用了共同的欧洲健康规划和目标。这项健康规划是比较系统的,对欧洲国家来说,非常重要的是懂得什么样的健康政策将会非常有效地改善公众的健康状态,同时又控制保健费用的增长。由世界卫生组织推荐的健康政策分... 详细信息

80年代初,欧洲国家第一次采用了共同的欧洲健康规划和目标。这项健康规划是比较系统的,对欧洲国家来说,非常重要的是懂得什么样的健康政策将会非常有效地改善公众的健康状态,同时又控制保健费用的增长。由世界卫生组织推荐的健康政策分析网络主要被用于分析北欧国家的健康政策和规划的实施。首先,描述了北欧国家的人人健康(HFA)规划的背景、目

关键词：健康政策欧洲初级卫生保健规划长远计划文件流动服务第一个所有

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中国家具在欧洲市场的发展态势

家具与室内装饰 2006年第2期13卷 37-41页

作者：尼克瑞屠祺（译）芬兰PARECO公司总经理不详

芬兰PARECO公司总经理尼克瑞先生(reijos·Nykri)应中国家具协会的邀请,于2005年11 月出席了在广东佛山市顺德乐从举办的“首届中国家具文化节”。在文化节的主题活动“中国家具营销论坛”上作了题为《中国家具在欧洲市场的发展态势》... 详细信息

芬兰PARECO公司总经理尼克瑞先生(reijos·Nykri)应中国家具协会的邀请,于2005年11 月出席了在广东佛山市顺德乐从举办的“首届中国家具文化节”。在文化节的主题活动“中国家具营销论坛”上作了题为《中国家具在欧洲市场的发展态势》的专题演讲。尼克瑞Nykyri先生曾任世界家具巨头宜家公司的营销经理,现任谊公司顾问,他在演讲中以大量详实的统计数据为基础,分析了欧洲的家具消费需,求并结合欧洲家具工业基本情况闻述了中国家具在欧洲市场的契机与前景。

关键词：中国家具欧洲市场家具文化主题活动统计数据消费需求家具工业总经理