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Systematic Biological Upgrade of a Urea Fertilizer Effluent Treatment Plant Using GPS

Open j.urnal of Applied Sciences 2023年第8期13卷 1457-1477页

作者： Isyaku Ahmad j.seph T. Akintola regina j. patinvoh Wilson F. Ekpotu Martins C. Obialor Philemon Chukwuebuka Udom Process (Urea) Department Dangote Fertiliser Limited Lagos Nigeria Department of Research & Development Vitapur Nigeria Limited Lagos Nigeria Department of Chemical Engineering Faculty of Engineering Lagos State University Lagos Nigeria Department of Chemical & Petroleum Engineering University of Uyo Akwa Ibom Nigeria Department of Chemical Engineering Federal University of Owerri Owerri Nigeria

The use of modeling and simulation has developed into a critical tool for the sustainable management of wastewater, especially when it comes to replicating the complex biochemical procedures required for fertilizer effluent treatment, which calls for a significant amount of wastewater-related data. The biological improvement of a urea fertilizer effluent via GPS* simulation was carried out in this work using a methodical process. Using established analytical techniques, temperature, total suspended solids (TSS), biochemical oxygen demand (BOD), total phosphorus (T/), chemical oxygen demand (COD), total nitrogen (TN), total nitrate (NO3), electric conductivity (EC), turbidity, residual chlorine, urea, NH3, and heavy metals (Cu, Cd, Cr, Pb, Ni, and Fe) were assessed. The research revealed that the measured values from the fertilizer factory outfall effluent had high concentrations of all the physicochemical water quality indicators, with the exception of TSS, PO4-, SO4-, and NO3-. These concentrations are higher compared to the authorized limits or suggested values by the Federal Environmental Protection Agency (FEPA). To improve the therapy biologically, however, a modeling and simulation program (GPS-X, version 8.0) was used with the physicochemical information gathered from the studied sample. The results of the treated water simulation showed that the concentrations of BOD5 and COD had been significantly reduced by 35% and 44%, respectively. Additionally, it was discovered that total phosphorus (TP), nitrate (N), and total nitrogen (TN) were all within the permitted FEPA limit. The results revealed good treatment performance of the wastewater with increasing concentration of acetic acid and sodium hydroxide. Hence, the results of this research work identify the need for proper treatment of fertilizer industry effluents prior to their release into the environment.

关键词： Fertilizer Wastewater Effluent Discharge Basin Outfall Basin Physiochemical Analysis GPS* Modelling & Simulation

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Ca^(2+) binding to the C_(2)E domain of otoferlin is required for hair cell exocytosis and hearing

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Protein & Cell 2024年第4期15卷 305-312页

作者： Han Chen Mehar Monga Qinghua Fang Louj.n Slitin j.kob Neef Shashank S.Chepurwar regina Célia Mingroni Netto Karina Lezirovitz Alfredo Tabith,j.. Fritz Benseler Nils Brose Kathrin Kusch Carolin Wichmann Nicola Strenzke Barbara Vona j.lia Preobraschenski Tobias Moser Institute for Auditory Neuroscience and InnerEarLab University Medical Center Göttingen37075 GöttingenGermany Collaborative Research Center 889 University of Göttingen37075 GöttingenGermany Auditory Neuroscience and Synaptic Nanophysiology Group Max Planck Institute for Multidisciplinary Sciences37075 GöttingenGermany Göttingen Graduate Center for Neurosciences Biophysics and Molecular BiosciencesUniversity of Göttingen37075 GöttingenGermany Biochemistry of Membrane Dynamics Group Institute for Auditory NeuroscienceUniversity Medical Center Göttingen37075 GöttingenGermany Molecular Architecture of Synapses Group Institute for Auditory Neuroscience and InnerEarLabUniversity Medical Center Göttingen37075 GöttingenGermany Center for Biostructural Imaging of Neurodegeneration University Medical Center Göttingen37075 GöttingenGermany Auditory Systems Physiology Group Institute for Auditory Neuroscience and InnerEarLabUniversity Medical Center Göttingen37075 GöttingenGermany Departamento de Genética e Biologia Evolutiva Centro de Pesquisas sobre o Genoma Humano e Células-TroncoInstituto de BiociênciasUniversidade de São PauloSão Paulo 05508-220Brazil Laboratório de Otorrinolaringologia/LIM32 Faculdade de MedicinaHospital das ClínicasUniversidade de São PauloSão PauloSP 05508-220Brazil DERDIC Pontifícia Universidade Católica de São PauloSão Paulo 05508-220Brazil Department of Molecular Neurobiology Max Planck Institute for Multidisciplinary Sciences37075 GöttingenGermany Multiscale Bioimaging Cluster of Excellence(MBExC) University of Göttingen37075 GöttingenGermany Functional Auditory Genomics Group Auditory Neuroscience and Optogenetics LaboratoryGerman Primate Center37077 GöttingenGermany Hearing Genomics Group Institute for Auditory Neuroscience and InnerEarLabUniversity Medical Center Göttingen37075 GöttingenGermany Institute of Human Genetics University Medical Center Göttingen37075 GöttingenGermany

Dear Editor,Afferent synapses of cochlear inner hair cells(IHCs)employ a unique molecular machinery(see extended background in Supplementary Materials).Otoferlin is a key player in this machinery and its defects cause human auditory synaptopathy(Moser and Starr,2016).Otoferlin,a tail-anchored(Vogl et al.,2016)multi-C_(2)-domain protein(Fig.1Ai)specific to hair cells(Roux et al.,2006),is a member of the ferlin protein family involved in membrane trafficking and repair that are of maj.r disease relevance(Pangršičet al.,2012),also see Supplementary *** is distributed broadly within IHCs(Fig.2Ai-Aiii;Pangrsic et al.,2010;Roux et al.,2006).

关键词： auditory hair

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Mathematical Modelling of Sterile Insect Technology for Mosquito Control

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Advances in Entomology 2014年第4期2卷 180-193页

作者： regina j.j.ho patinvoh Alfred Akpoveta Susu Department of Chemical & Polymer Engineering Lagos State University Lagos Nigeria Department of Chemical Engineering University of Lagos Lagos Nigeria

Reduction of mosquito populations will, at least, reduce substantially the transmission of malaria disease. One potential method of achieving this reduction is the environmentally-friendly population control method known as the Sterile Insect Control (SIT) method. The SIT method has so far not been widely used against insect disease vectors, such as mosquitoes, because of various practical difficulties in rearing, sterilization and distribution of the parasite population. For mosquitoes, male-only release is considered essential since sterile females will bite and so may transmit disease, whereas male mosquitoes do not bite. This work concerns the mathematical modelling of the effectiveness of Sterile Insect Technique for Aedes aegypti mosquitoes, when the female sexual preference is incorporated. We found that for a released value of the sterile male mosquito below 40,000, the wild mosquito population decreases over time while the sterile male mosquito population increases. Therefore, the transmission of malaria and dengue infection declines because the sterile male mosquitoes dominated the environment. We also found that for a released value of the sterile male mosquito above 40,000, the wild mosquito population decreases and the sterile male mosquito population decreases as well. Therefore, if the inj.ction of sterile male mosquitoes is large enough, the environment will be rid of mosquitoes over time. The result also shows that if sexual selection is incorporated into a reaction diffusion system, modelling the spread of Aedes aegypti mosquitoes, the Sterile Insect Technique (SIT) will still be a successful control measure.

关键词： Sterile Insect Technique (SIT) Aedes aegypti Mosquitoes Environment Malaria Control Computer Simulation

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A Web System for Choose Your Own Adventure

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j.urnal of Computer and Communications 2014年第4期2卷 182-187页

作者： Zizhong j. Wang regina L. Barner 1College of Information Engineering Taiyuan University of Technology Taiyuan China 2Department of Mathematics and Computer Science Virginia Wesleyan College Norfolk USA Department of Mathematics and Computer Science Virginia Wesleyan College Norfolk USA

The Web system for Choose Your Own Adventure (CYOA) proj.ct utilizes the PHP and MySQL programming languages for an entertainment purpose. This proj.ct creates a fully-functional and se- cure online user system, in which the accounts of the user system are stored in a MySQL database. Over the duration of this proj.ct, it is found that the PHP and MySQL programming languages are able to be employed for entertainment purposes, and they are both very effective in the field of entertainment. This proj.ct is meant to broaden the horizons of aspiring programmers in order to give them a glimpse into a possibility of using these programming languages in a scope that is commonly broached by game developers, but not programmers in the usual case.

关键词： Web System PHP/MySQL Entertainment Game Developer

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Does the root to shoot ratio show a hormetic response to stress? An ecological and environmental perspective

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j.urnal of Forestry Research 2019年第5期30卷 1569-1580页

作者： Evgenios Agathokleous regina G.Belz Mitsutoshi Kitao Takayoshi Koike Edward j.Calabrese Hokkaido Research Center Forestry and Forest Products Research Institute(FFPRI)Forest Research and Management Organization7 HitsujigaokaSapporoHokkaido 062-8516Japan Research Faculty of Agriculture Hokkaido UniversityKita 9 Nishi 9SapporoHokkaido 060-8589Japan Agroecology Unit Hans-Ruthenberg InstituteUniversity of HohenheimGarbenstra遝 1370599 StuttgartGermany Department of Environmental Health Sciences Morrill IN344University of MassachusettsAmherstMA 01003USA

Root/shoot(R/S)ratio is an important index for assessing plant health,and has received increased attention in the last decades as a sensitive indicator of plant stress induced by chemical or physical *** R/S ratio has been discussed in the context of ecological theory and its potential importance in ecological succession,where species follow different strategies for above-ground growth for light or below-ground competition for water and *** present evidence showing the R/S ratio follows a biphasic dose–response relationship under stress,typical of *** R/S ratio in response to stress has been widely compared among species and ecological succession *** is constrained by a variety of factors such as ***,the current literature lacks dose-response studies incorporating the full dose–response continuum,hence limiting scientific understanding and possible valuable *** data presented provide an important perspective for new-generation studies that can advance current ecological understanding and improve carbon storage estimates by R/S ratio *** response of the R/S ratio can have an important role in forestry for producing seedlings with desired characteristics to achieve maximum health/productivity and resilience under plantation conditions.

关键词： Biological plasticity Biphasic response Hormesis Plant stress Root/shoot ratio

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Perturbation Experiments in Community Plant Species during Recovery from Agricultural Abandonment in a Semi-Arid Region of Central-Western Spain

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j.urnal of Environmental Protection 2016年第11期7卷 1618-1644页

作者： j. E. Alvarez-Diaz M. C. Santa-regina I. Santa-regina Universidad de Antioquía Medellín Colombia Instituto Arcipreste de Hita Madrid Spain IRNASA-CSIC Cordel de Merinas Salamanca Spain

Background: Can high diversity mixtures of later succession plant species be able to suppress early successional (arable weed) species than low diversity species mixtures? Can the removal of plant functional groups have important consequences on the sys-tem stability? Location: The study area was located at 850 m a.s.l., fifteen kilometers (15 km) to the west of Salamanca city, Spain, in a dehesa-like woodland. Methods: The field experiment was installed in Spring 1996 (May). The plots represented former agricultural lands cropped with (a rotation of) monocultures and abandoned right at the beginning of the experiment after the last crop was harvested in 1995. Before in-stalling plots, the fields were harrowed and equalized. The treatments (NC-natural colonization, LD-low diversity seed mixture and HD-high diversity seed mixture) were randomly allocated to the plots in each block. The experiment was organised accord-ing to a block design with five replicate blocks. Within each block, four plots measur-ing 10 × 10 m were marked out and each of the three treatments was randomly as-signed to one plot. All plots were separated by 2 m walkways. Results: The competitive ability of the sown species in different mixtures in LD, valued on the basis of their performance in HD, is a good predictor of their ability to suppress the weed crops spe-cies. This was also corroborated by the high relationship between the efficiency of the sown species in both treatments of species mixture (R2 = 0.51, F (1, 33) = 34.56, P < 0.001). Conclusions: The increase of colonizing species cover was significantly lower in LD, which again supported the increase of biomass in 1998, being also lower in HD. Therefore, this increase in the community is more prominent in LD treatments. The effect of sown species was not so important in this increase.

关键词： Colonization Ecosystem Functioning Invasibility Restoration Sowing Experiment Species Richness

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Quantitation of Genetox Impurities Using a Surrogate Standard Approach

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j.urnal of Analytical Sciences, Methods and Instrumentation 2013年第3期3卷 167-172页

作者： Heather Wang regina Nardi Yuri Bereznitski Roy Helmy David j. Waterhouse Analytical Chemistry Merck Research Laboratories Merck Sharp & Dohme Corp. Rahway USA.

With the ever increasing complexity of active pharmaceutical ingredient (API) preparations, more potential genotoxic impurities (PGI’s) are being observed. It is thus necessary to determine if these PGI’s are present in the final API’s, and if they are present, to ensure the levels are acceptable for any clinical uses. For PGI’s that have authentic standards available, quantitation can be accomplished in a straightforward manner. However, for PGI’s that are expected to form through rearrangements or side reactions, authentic standards may not be readily available, significantly complicating the analysis. In this study we describe a surrogate standard approach for quantifying PGI’s that allows for relative response factor calculations of PGI species utilizing both gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS).

关键词： Potential Genotoxic Impurity (PGI) Active Pharmaceutical Ingredient (API) Mass Spectrometry Surrogate Standard Analyte Relative Response Factor (RRF)

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Selective Pb^(2+) removal and electrochemical regeneration of fresh and recycled FeOOH

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Nano Research 2023年第7期16卷 9352-9363页

作者： Lei Wang Lexane Deligniere Samantha Husmann regina Leiner Carsten Bahr Shengj.e Zhang Chaochao Dun Matthew M.Montemore Markus Gallei j.ffrey j.Urban Choonsoo Kim Volker Presser INM—Leibniz Institute for New Materials Campus D22Saarbrücken 66123Germany Department of Materials Science and Engineering Saarland UniversityCampus D22Saarbrücken 66123Germany Polymer Chemistry Saarland UniversityCampus C42Saarbrücken 66123Germany 4 GEH Wasserchemie GmbH&Co.KGAdolf-Köhne-Straße Osnabrück 49090 Germany Department of Chemical and Biomolecular Engineering Tulane UniversityNew OrleansLA 70118USA The Molecular Foundry Lawrence Berkeley National Laboratory BerkeleyBerkeleyCA 94720USA Saarene-Saarland Center for Energy Materials and Sustainability Campus C42Saarbrücken 66123Germany Department of Environmental Engineering with Institute of Energy/Environment Convergence Technologies Kongju National University1223-24 Cheonan-daeroCheonan-si 31080Republic of Korea Department of Future Convergence Engineering Kongju National University1223-24 Cheonan-daeroCheonan-si 31080Republic of Korea

Heavy metal pollution is a key environmental *** extracting heavy metals could accomplish water purification and resource recycling *** is a promising approach with a facile process,adaptability for the broad concentration of feed water,and high ***,the adsorption method faces challenges in synthesizing highperformance sorbents and regenerating adsorbents *** is an environmentally friendly sorbent with low-cost production on a large ***,the selectivity behavior and regeneration of FeOOH are seldom ***,we investigated the selectivity of FeOOH in a mixed solution of Co^(2+),Ni^(2+),and Pb^(2+)and proposed to enhance the capacity of FeOOH and regenerate it by using external *** charge,the FeOOH electrode shows a Pb^(2+)uptake capacity of 20 mg/*** applying a voltage of-0.2/+0.8 V,the uptake capacity increases to a maximum of 42 mg/g and the desorption ratio is 70%-80%.In 35 cycles,FeOOH shows a superior selectivity towards Pb^(2+)compared with Co^(2+)and Ni^(2+),with a purity of 97%±3%in the *** high selectivity is attributed to the lower activation energy for Pb^(2+)*** capacity retentions at the 5^(th)and the 35^(th)cycles are ca.80%and ca.50%,respectively,comparable to the chemical regeneration *** industrially exhausted granular ferric hydroxide as the electrode material,the system exhibits a Pb^(2+)uptake capacity of 37.4 mg/g with high *** work demonstrates the feasibility of regenerating FeOOH by charge and provides a new approach for recycling and upcycling FeOOH sorbent.

关键词： FeOOH electrochemical regeneration selective separation heavy metal ions

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Study on Strategies for Methane Inj.ction in a DISI （Direct Inj.ction Spark Ignition） Engine

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j.urnal of Energy and Power Engineering 2014年第2期8卷 298-305页

作者： Fernanda P. Martins Francisco j. de Souza Pedro T. Lacava Claudia regina de Andrade Aeronautical Technology Institute S6o Jos dos Campos SP12228-900 Brazil Federal University of Uberlfindia UFU Uberlfindia SP38408-100 Brazil

This paper deals with the application of two different inj.ction strategies in a natural gas direct inj.ction spark ignition single-cylinder engine model. The analysis includes the air flow characterization during compression stroke and also the charge stratification. Two different swirl ratios are applied and piston bowl effects are analyzed during the gas j.t deflection towards the spark plug. Achieving wall-guided effect, consequently, the charge stratification in spark plug region is obtained. The goal is to study the mixture formation differences for a single and a bi pulsed CNG （compressed natural gas） inj.ction profiles and check the evolution of the methane concentration at the spark plug at the start of combustion.

关键词： DISI (direct inj.ction spark ignition) methane inj.ction profile.

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3.0 Tesla vs 1.5 Tesla breast magnetic resonance imaging in newly diagnosed breast cancer patients

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World j.urnal of Radiology 2013年第8期5卷 285-294页

作者： Reni S Butler Christine Chen Reena Vashi regina j.Hooley Liane E Philpotts Department of Diagnostic Radiology Yale University School of Medicine Department of Diagnostic Radiology Memorial Hermann Healthcare System

AIM:To compare 3.0 Tesla(T) vs 1.5T magnetic resonance(MR) imaging systems in newly diagnosed breast cancer ***:Upon Institutional Review Board approval,a Health Insurance Portability and Accountability Actcompliant retrospective review of 147 consecutive 3.0T MR examinations and 98 consecutive 1.5T MR examinations in patients with newly diagnosed breast cancer between 7/2009 and 5/2010 was *** patients who underwent neoadj.vant chemotherapy in the 3.0T group were *** occult suspicious lesions(BIRADS Code 4 and 5) additional to the index cancer in the ipsilateral and contralateral breast were *** characteristics and pathologic diagnoses were recorded,and results achieved with both systems *** significance was analyzed using Fisher’s exact ***:In the 3.0T group,206 suspicious lesions were identified in 55%(75/136) of patients and 96%(198/206) of these lesions were *** the 1.5T group,98 suspicious lesions were identified in 53%(52/98) of patients and 90%(88/98) of these lesions were *** results yielded additional malignancies in 24% of patients in the 3.0T group vs 14% of patients in the 1.5T group(33/136 vs 14/98,P = 0.07).Average size and histology of the additional cancers was *** patients who had a suspicious MR imaging study,additional cancers were found in 44% of patients in the 3.0T group vs 27% in the 1.5T group(33/75 vs 14/52,P = 0.06),yielding a higher positive predictive value(PPV) for biopsies performed with the 3.0T ***:3.0T MR imaging detected more additional malignancies in patients with newly diagnosed breast cancer and yielded a higher PPV for biopsies performed with the 3.0T system.

关键词： Breast Breast cancer Cancer staging Outcome Magnetic resonance imaging Breast magnetic resonance imaging 3 Tesla Technical

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