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量子光学学报 2006年第B8期12卷 57-57页

作者： Surendra Singh reeta vyas Physics Department University of Arkansas Fayetteville AR 72701 USA

Conditional Detection of Fluctuations of Light from an Optical Cavity with One Atom

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Conditional Detection of Fluctuations of Light from an Optic...

Conditional Detection of Fluctuations of Light from an Optical Cavity with One Atom

第十二届全国量子光学学术会议

作者： reeta vyas Justin Vines Surendra Singh Physics Department University of Arkansas Fayetteville AR 72701USA Physics Department University of Arkansas Fayetteville AR 72701USA Physics Department University of Arkansas Fayetteville AR 72701USA

＜正＞Fluctuations of light provide a window on the underlying quantum dynamical evolution of the source emitting light. Emission of a photon by a source signals quantum fluctuations in progress. Hence a measurement that is conditioned upon a photodetection allows us to follow the time evolution of the fluctuations and the framework of conditioned measurements provides a powerful conceptual tool for understanding nonclassical features of quantum dynamics. We discuss the connection between quantum dynamics and photon fluctuations in terms of conditional

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量子光学学报 2006年第B8期12卷 64-64页

作者： reeta vyas Justin Vines Surendra Singh Physics Department University of Arkansas Fayetteville AR 72701 USA

Incense smoke(IS)inhalation exposure system:Physicochemical characterization,IS particle deposition and clearance in human airway using MPPD model

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Particuology 2024年第4期87卷 271-285页

作者： vyas Kumar Hafsa Hashmi Anshita Nasreen Ghazi Ansari Jyotsna Singh Inhalation Toxicology Facility Regulatory Toxicology GroupCSR-Indian Institute of Toxicology ResearchLucknow22001UPIndi Academy of Scientific and Innovative Research(AcsSIR) Ghaziabad201002UPIndia Analytical Chemistry Regulatory Toxicology GroupCSIR-Indian Institute of Toxicology ResearchLucknow226001UPIndia

Incense smoke(IS)is source of indoor air pollution and key risk for diverse human *** in-formation is available regarding controlled IS rodent inhalation exposure system and IS particulate matter(PM)deposition in human *** aimed to demonstrate stable ISPM physicochemical parameters of 10 incense products inside the customized whole body inhalation exposure chamber(without animal)connected to smoke generation unit via aerosol mixing *** analyzed for size segregated PM emission,ISPM in vitro aerodynamics(MMAD and GSD determination),fine and ultrafine particle's SEM,SEM-EDX and PAH *** real life exposure scenario by utilizing MMAD,GSD and PM concentration after Tier 1 exposure assessment as key input parameters,ISPM dosimetry in infant(3 months)and adult(21 years male and female)human airways was calculated using multiple-path particle dosimetry(MPPD 3.04)*** median aerodynamic diameter(MMAD)and geo-metric standard deviation(GSD)ranged between 0.55 and 2.10μm and 1.22 to 1.77(polydisperse)***1.0 and PM0.1 showed multiple morphology and presence of heavy and trace *** like acenaphthylene,anthracene,fluorene,naphthalene and phenanthrene were detected(0.84-143.17μg/g).MPPD results showed higher ISPM deposition in pulmonary region and lowest in trachea bronchial *** deposition in tissue was higher in lower,peripheral lung as compared to upper and central lung *** body inhalation exposure system showed stable IS atmosphere(physi-cochemical parameters)indicating the device suitability in future inhalation *** ISPM deposition fraction and clearance data showed deep lung penetrating and retention behavior with higher risk in infant followed by female and then *** modeled particle deposition and clearance data may be useful in risk assessment analysis of IS.

关键词： Inhalation Incense smoke Multiple-path particle dosimetry(MPPD) Particle deposition Particulate matter(PM) Mass median aerodynamic diameter (MMAD) Human airway

Optimization of variables and assessment of in-vitro and in-vivo antihyperlipidemic activity of Eudragit RS nanoparticles containing simvastatin

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Particuology 2024年第7期90卷 189-198页

作者： Bina Gidwani Vishal Jain Veenu Joshi Ravindra Kumar Pandey Shiv Shankar Shukla Amber vyas Columbia Institute of Pharmacy Raipur(C.G.)India University Institute of Pharmacy Pt Ravishankar Shukla UniversityRaipur(C.G.)India Center for Basic Science and Research Pt Ravishankar Shukla UniversityRaipur(C.G.)India

Simvastatin, a BCS class II drug, is associated with poor aqueous solubility, first-pass metabolism and short half-life. In the present work, nanoparticles were prepared and evaluated. Optimization of formulation and process parameters was done through the use of independent and dependent variables. Preliminary studies were done to determine suitable range of the concentration of Eudragit polymer (10%–30%) and the ratio of drug to polymer (1:1 to 1:5) for the formation of nanoparticles by emulsification and a solvent evaporation technique. Results revealed that the mean size of nanoparticles was affected by stirring speed from 5000 RPM, 8000 RPM, and 12000 RPM. The results of increase in association efficiency and percent yield with increase in amount of drug from 100 mg, 150 mg, and 200 mg in selected range were observed. In-vitro release studies showed that two formulations possess highest initial burst and slow sustained drug release. There was 2.93-fold decrease in total cholesterol and 3.27-fold increases in triglyceride level during in-vivo study.

关键词： Simvastatin Eudragit RS 100 Nanoparticles Hyperlipidemia

Multidimensional evaluation of salt tolerance in groundnut genotypes through biochemical responses

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Oil Crop Science 2024年第2期9卷 102-110页

作者： Rushita D.Parmar Vaishali G.Varsani Vijay Parmar Suhas vyas Dushyant Dudhagara Department of Life Sciences Bhakta Kavi Narsinh Mehta UniversityJunagadhGujaratIndia

The manuscript explores the complex interplay between groundnut genotypes,salt tolerance and hormonal influence,shedding light on the dynamic responses of three specific groundnut genotypes,KDG-128,TG-37 A and GG-20,to salt treatments and gibberellic acid(GA3).The study encompasses germination,plant growth,total protein content and oil content as key *** comprehensive analysis,it identifies TG-37 A and KDG-128 as salt-tolerant genotypes,and GG-20 as salt-susceptible genotypes,which highlighting the potential for targeted breeding efforts to develop more resilient groundnut ***,the quantification of protein and oil content under different treatments provides vital data for optimizing nutritional profiles in groundnut *** Component Analysis(PCA) underscores the significance of the first principal component(PC1)in explaining the majority of variance,capturing primary trends and differences in plant *** of Variance(ANOVA) and hierarchical analysis confirm the presence of statistically significant differences in protein and oil content among the ***'s correlation coefficient matrix analysis reveals strong positive correlations between plant length and protein content,plant length and oil content,and a moderately positive correlation between protein content and oil *** findings provide valuable insights into groundnut physiology,salt tolerance,and nutritional composition,with implications for future research in sustainable agriculture and crop improvement.

关键词： Groundnut Salt tolerance Genotypes Salt-hormone interaction Protein and oil content Statistical analysis

Impact of D-dimer on in-hospital mortality following aortic dissection:A systematic review and meta-analysis

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World Journal of Cardiology 2024年第6期16卷 355-362页

作者： Sashwath Srikanth Shabnam Abrishami Lakshmi Subramanian Ashwini Mahadevaiah Ankit vyas Akhil Jain Sangeetha Nathaniel Subramanian Gnanaguruparan Rupak Desai Department of Medicine ECU Health Medical CenterGreenvilleNC 27834United States Department of Research Independent Outcomes ResearchLos AngelesCA 90036United States Harvard T.H.Chan School of Public Health Harvard UniversityBostonMA 02115United States Department of Vascular Medicine Ochsner Clinic FoundationNew OrleansLA 70121United States Department of Leukemia The University of Texas MD Anderson Cancer CenterHoustonTX 77079United States Department of Cardiology Heart and Vascular ClinicNewarkDE 19713United States Independent Researcher AtlantaGA 30079United States

BACKGROUND The utility of D-dimer(DD)as a biomarker for acute aortic dissection(AD)is ***,its predictive value for in-hospital mortality remains uncertain and subject to conflicting *** To conduct a meta-analysis of AD-related in-hospital mortality(ADIM)with elevated DD *** We searched PubMed,Scopus,Embase,and Google Scholar for AD and ADIM literature through May *** was assessed using I2 statistics and effect size(hazard or odds ratio)analysis with random-effects *** size,study type,and patients’mean age were used for subgroup *** significance threshold was P60 *** and larger sample size studies(n>250)demonstrated a heightened likelihood of ADIM associated with elevated DD levels(effect size:2.57,95%CI:1.30-5.08,P<0.01 vs effect size:1.05,95%CI:1.00-1.11,P=0.05,respectively).CONCLUSION Our meta-analysis shows elevated DD increases in-hospital mortality risk in AD patients,highlighting the need for larger,prospective studies to improve risk prediction models.

关键词： D-dimer Aortic dissection Mortality Biomarker Systematic review Meta-analysis

Unveiling resveratrol’s potential:Navigating the landscape of autoimmune diseases

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Clinical Traditional Medicine and Pharmacology 2024年第3期5卷 87-95页

作者： Keshava Jetha Arya vyas Ashutosh Tripathi Jeet Gandhi Vivek Chavda Department of Pharmaceutics and Pharmaceutical Technology L.M.College of PharmacyAhmedabad380009GujaratIndia Ph.D.Section Gujarat Technological UniversityAhmedabad382424GujaratIndia Ph.D.Section Kadi Sarva VishvavidyalayaGandhinagar382024GujaratIndia

Background:Autoimmune diseases pose a multifaceted challenge in the realm of medical science,warranting in-novative approaches for their ***,a naturally ccurring compound found in various dietary sources,has captured attention for its potential immunomodulatory and anti-inflammatory ***-standing the interplay between autoimmune diseases and resveratrol is crucial for exploring novel therapeutic ***:This review aims to explore the intricate relationship between autoimmune diseases and *** seeks to provide insights into the mechanistic underpinnings of autoimmune diseases,emphasizing the necessity for innovative therapeutic ***,it aims to comprehensively discuss the pharmacological properties of resveratrol and its potential applications in managing autoimmune ***:A structured review approach was employed to organize the content into distinct *** literature searches were conducted to gather information on autoimmune diseases,the pharmacology of resvera-trol,and its effects on immune regulation,inflammation,and oxidative *** and clinical evidence regarding the efficacy of resveratrol in managing specific autoimmune diseases was critically ***:Resveratrol demonstrates immunomodulatory,anti-inflammatory,and antioxidant effects,which are rel-evant to autoimmune disease *** properties impact immune cell regulation,pro-inflammatory cytokines,inflammatory mediators,and oxidative stress,potentially ameliorating autoimmune *** studies present promising evidence for the efficacy of resveratrol in conditions such as rheumatoid arthri-tis,systemic lupus erythematosus,multiple sclerosis,and inflammatory bowel disease,albeit further research is necessary to determine its safety and optimal ***:The review underscores the promising potential of resveratrol in autoimmune disease *** targeting k

关键词： Autoimmune diseases Resveratrol Immunomodulation Anti-inflammatory Antioxidant Clinical trials Translational research

Efficacy and safety of abrocitinib in Chinese patients with moderate-to-severe atopic dermatitis: A post hoc analysis of the JADE REGIMEN phase 3 trial

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中华医学杂志(英文版) 2024年第16期137卷 2024 Jul 15页

作者： Li Hang Cheng Hao Lu Qianjin Lai Wei Tao Xiaohua Encinas Gerardo A. vyas Shefali Wang Bo Luo Xin Li Shiqi Department of Dermatology Peking University First Hospital National Clinical Research Center for Skin and Immune Diseases Beijing China Department of Dermatology Sir Run Run Shaw Hospital Zhejiang University School of Medicine Hangzhou Zhejiang China Department of Dermatology The Second Xiangya Hospital of Central South University Changsha Hunan China Department of Dermatology The Third Affiliated Hospital of Sun Yat-sen University Guangzhou Guangdong China Department of Dermatology Zhejiang Provincial People’s Hospital Hangzhou Medical College Hangzhou Zhejiang China Pfizer S.A. de C.V. Mexico City Mexico Pfizer Inc. New York NY USA Pfizer Investment Co. Ltd Beijing China Pfizer (China) R& D Co. Ltd Shanghai China Pfizer PBG Shanghai China