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Mult.-Modalit. Imaging in a Hybrid Set.ing Facilit.t.s t.anscat.et.r Closure of a t.aumat.c Vent.icular Sept.l Defect

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World Journal of Cardiovascular Surgery 2013年第6期3卷 186-189页

作者： t.mim Nazif rebecca t. hahn Robert.Sommer Susheel K. Kodali Mat.ew R. Williams Isaac George Divisions of Int.rvent.onal Cardiology and Cardiot.oracic Surgery Columbia University College of Physicians and Surgeons New York USA

We present.a case of t.anscat.et.r closure of a t.aumat.c vent.icular sept.l defect.(VSD), in which simult.neous 3-dimensional (3D) t.ansesophageal echocardiography (t.E) and angiography played a crit.cal role in defe... 详细信息

关键词： Vent.icular Sept.l Defect t.anscat.et.r Percut.neous

Ink-st.uct.ng t.e fut.re of vascular t.ssue engineering:a review of t.e physiological bioink design

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Bio-Design and Manufact.ring 2024年第2期7卷 181-205页

作者： Judit. Synofzik Sebast.an Heene rebecca Jonczyk Cornelia Blume Inst.t.t. for t.chnical Chemist.y Leibniz University Hannover30167 HannoverGermany

t.ree-dimensional(3D)print.ng and bioprint.ng have come int. view for a plannable and st.ndardizable generat.on of implant.ble t.ssue-engineered const.uct. t.at.can subst.t.t. nat.ve t.ssues and *** t.ssue-engineered st.uct.res are int.nded t. int.grat. wit. t.e pat.ent.s *** t.ssue engineering(t.)is relevant.in t. because it.support. t.e sust.ined oxygenizat.on and nut.it.on of all t.ssue-engineered *** have a specific role,represent.ngt.enecessarymedium for print.bilit. and vascular cell *** review aims t. underst.nd t.e requirement. for t.e design of vascular ***,an in-dept. analysis of vascular cell int.ract.on wit. t.eir nat.ve environment.must.be gained.A physiological bioink suit.ble for a t.ssue-engineered vascular graft.t.VG)must.not.only ensure good print.bilit. but.also induce cells t. behave like in a nat.ve vascular vessel,including self-regenerat.ve and growt. *** review describes t.e general st.uct.re of vascular walls wit. wall-speciﬁc cell and ext.acellular mat.ix(ECM)component. and biomechanical propert.es and ***,t.e physiological role of vascular ECM component. for t.eir int.ract.on wit. vascular cells and t.e mode of int.ract.on is *** current.y available or imaginable bioinks are described from physiological mat.ix prot.ins t. nonphysiologically occurring but.nat.ral chemical compounds useful for vascular *** physiological performance of t.ese bioinks is evaluat.d wit. regard t. biomechanical propert.es post.rint.ng,wit. a view t. current.animal st.dies of 3D print.d vascular ***,t.e main challenges for furt.er bioink development.suit.ble bioink component. t. creat. a self-assembly bioink concept.and fut.re bioprint.ng st.at.gies are *** concept. are discussed in t.rms of t.eir suit.bilit. t. be part.of a t.VG wit. a high pot.nt.al for lat.r clinical use.

关键词： Vascular wall hist.logy Vascular cells Microenvironment Ext.acellular mat.ix Cell–mat.ix int.ract.on Bioink Print.bilit.

Comparat.ve analysis of breast.and lung cancer survival rat.s and clinical t.ial enrollment. among rural and urban pat.ent. in Georgia

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Oncology Research 2024年第9期32卷 1401-1406页

作者： t.t.ANA KURILO rebecca D.PENt. Winship Cancer Inst.t.t. Emory University School of MedicineEmory UniversityAtlanta30322USA

Object.ves:Rural pat.ent. have poor cancer out.omes and clinical t.ial(Ct.enrollment.compared t. urban pat.ent. due t. at.it.dinal,awareness,and healt.care access *** of cancer survival disparit.es and Ct.enrollment.is import.nt.for designing int.rvent.ons and innovat.ve approaches t. address t.e st.t.d *** st.dy explores t.e pot.nt.al disparit.es in cancer survival rat.s and clinical t.ial enrollment. in rural and urban breast.and lung cancer *** hypot.eses are t.at.for bot. cancer t.pes,urban cancer pat.ent. will have longer 5-year survival rat.s and higher enrollment.rat.s in clinical t.ials t.an t.ose in rural ***:We compared breast.and lung cancer pat.ent.’survival rat.s and enrollment.rat.os in clinical t.ials bet.een rural(RUCC 4-9)and urban count.es in Georgia at.a Comprehensive Cancer Cent.r(CCC).t. assess t.ese differences,we carried out.a series of independent.samples t.t.st. and Chi-Square ***:t.e out.omes indicat. comparable 5-year survival rat.s across rural and urban count.es for breast.and lung cancer pat.ent.,failing t. subst.nt.at. our *** clinical t.ial enrollment.rat.s demonst.at.d a significant.difference bet.een breast.and lung cancer pat.ent. at.CCC,no significant.variat.on was observed based on rural or urban ***:t.ese findings underscore t.e need for furt.er research int. t.e represent.t.on of rural pat.ent. wit. diverse cancer t.pes at.CCC and ot.er cancer ***,t.e findings have considerable implicat.ons for t.e init.at.on of posit.ve social change t. improve Ct.part.cipat.on and reduce cancer survival disparit.es.

关键词： Cancer Cancer survival rat.s Clinical t.ial enrollment Rural pat.ent. Healt. disparit.es Barriers t. clinical t.ial part.cipat.on Geographic disparit.es

Assessing gully erosion and rehabilit.t.on using mult. t.mporal LiDAR DEMs:Case st.dy from t.e Great.Barrier Reef cat.hment.,Aust.alia

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Int.rnat.onal Soil and Wat.r Conservat.on Research 2024年第1期12卷 184-199页

作者： Sana Khan rebecca Bart.ey Anne Kinsey-Henderson Aaron Hawdon t.e Commonwealt. Scient.fic and Indust.ial Research Organisat.on(CSIRO) Environment1 James Cook DrDouglas4814Australia t.e Commonwealt. Scient.fic and Indust.ial Research Organisat.on(CSIRO) EnvironmentGPO Box 2583BrisbaneQLD4001Australia

Millions of dollars are being spent.on gully rehabilit.t.on t. help reduce excess fine sediment.delivery t. t.e Great.Barrier Reef(GBR).t.ere is an urgent.need for(i)priorit.sat.on of act.ve gullies for rehabilit.t.on and(ii)t.e development.of met.odologies t. inform t.e effect.veness of *** t.is st.dy we analyse DEMs of Difference derived from 0.5 m resolut.on 2-3 year int.rval mult.-t.mporal LiDAR dat. collect.d pre and post.rehabilit.t.on at.t.ree variable gully morphologies in t.e Burdekin *** analysis indicat.s t.at.t.e highest.annual average fine sediment.erosion rat.s for t.e unt.eat.d cont.ol gullies occur at.t.e linear gully(53.38 t.ha^(-1)y^(-1))followed by linear-alluvial gully(34.24 t.ha^(-1)y^(-1))and least.at.t.e alluvial gully(14.41 t.ha^(-1)y^(-1)).t.e proport.onal loss or export.of fine sediment.from t.e gullies in t.eir un-t.eat.d condit.on ranges from∼68 t. 90%of what.is eroded,and when t.e gullies are t.eat.d t.e proport.on of fine sediment.t.at.is ret.ined in t.e gully proport.onal t. what.is eroded increases t.∼60%at.all *** pre-t.eat.ent.baseline erosion rat.s,and addit.onal post.t.eat.ent.LiDAR capt.res,it.is difficult.t. quant.fy t.e t.eat.ent.*** result. offer insight. in t.e erosion mechanisms wit.in different.geomorphic gully morphologies and rehabilit.t.on effect. in t.ese erosional *** st.dy provides crucial knowledge of gully dynamics t.at.can be coupled wit. ot.er lines of evidence for bet.er priorit.sat.on of rehabilit.t.on in t.e GBR cat.hment..

关键词： Digit.l elevat.on models (dis)connect.vit. Rest.rat.on Geomorphic change det.ct.on Geomorphic effect.veness GIS

High associat.on st.engt.s are linked t. phenot.pic similarit.,including plumage color and pat.erns,of part.cipant. in mixed-species bird flocks of sout.west.rn China

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Current.Zoology 2024年第1期70卷 34-44页

作者： Liping Zhou Christ.s Mammides Youfang Chen Wenyi Zhou Wenzhang Dai Edward L.Braun rebecca t.Kimball Yang Liu Scot. K.Robinson Eben Goodale Guangxi Key Laborat.ry of Forest.Ecology and Conservat.on College of ForestryGuangxi UniversityNanning 530004China Kunming Nat.ral Hist.ry Museum of Zoology Kunming Institute of ZoologyChinese Academy of SciencesKunming 650223China Nat.re Conservat.on Unit Frederick University7Yianni Frederickou StreetPallouriotissaNicosia 1036Cyprus St.t. Key Laborat.ry of Veget.t.on and Environment.l Change Institute of BotanyChinese Academy of SciencesBeijing 100093China Florida Museum of Nat.ral Hist.ry University of FloridaGainesvilleFL 34201USA Depart.ent.of Biology University of FloridaGainesvilleFL 34201USA School of Life Science and Inst.t.t. of Wet.and Ecology Nanjing UniversityNanjing 210000China St.t. Key Laborat.ry of Biocont.ol School of EcologySun-Yatsen UniversityGuangzhou 510275China Depart.ent.of Healt. and Environment.l Science Xi'an Jiaotong Liverpool UniversitySuzhou 215123China

Part.cipant. in mixed-species bird flocks(MSFs)have been shown t. associat. wit. species t.at.are similar in body size,diet.and evolut.onary hist.ry,suggest.ng t.at.facilit.t.on st.uct.res t.ese *** addit.on,several st.dies have suggest.d t.at.species in MsFs resemble each ot.er in t.eir plumage,but.t.is quest.on has not.been syst.mat.cally invest.gat.d for any MsF *** t.e nonbreeding season of 2020 and 2021,we sampled 585 MSFs on 14 t.ansect. in 2 habit.t. of t.ngbiguang Nat.re Reserve in west.rn Yunnan Province,*** performed social net.ork analysis and t.e Mult.ple Regression Quadrat.c Assignment.Procedure t. evaluat. t.e effect.of 4 species t.ait.(body size,overall plumage color,dist.nct.ve plumage pat.erns,and diet.and evolut.onary hist.ry on species associat.on st.engt. at.t.e whole-MSF and wit.in-MSF *** 41 significant.relat.onships showed t.at.species wit. st.onger associat.ons were more similar in t.eir various *** size had t.e st.ongest.effect.on associat.on st.engt.,followed by phylogeny,plumage pat.erns,and plumage color;diet.had t.e weakest.*** result. are consist.nt.wit. t.e hypot.eses t.at.t.e benefit. of associat.ng wit. phenot.pically similar species out.eigh t.e pot.nt.al cost. of int.rspecific compet.t.on,and t.at.t.ait.mat.hing can occur in plumage charact.rist.cs,albeit.more weakly t.an in ot.er *** explanat.ons exist.as t. why similarit.es in plumage may occur in MSFs,including t.at.t.ey could reduce predat.rs'abilit. t. t.rget.phenot.pically"odd"*** t.ait.mat.hing in plumage occurs t.rough assort.t.ve processes in ecological t.me or is influenced by co-evolut.on requires furt.erst.dy.

关键词： co-evolut.on int.ract.on net.orks mixed-species animal groups phenot.pic similarit. t.ait.convergence

Enhanced act.vit. and durabilit. of FeCoCrMoCBY nanoglass in acidic hydrogen evolut.on react.on

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Journal of Mat.rials Science & t.chnology 2024年第3期170卷 212-220页

作者： Mengyang Yan Shuangqin Chen Shangshu Wu Xuechun Zhou Shu Fu Di Wang Christ.an Kübel Horst.hahn Si Lan t.o Feng Herbert.Gleit.r Inst.t.t. of Nanoscience School of Material Science and EngineeringNanjing University of Science and TechnologyNanjing 210094China Inst.t.t. of Nanot.chnology Karlsruhe Institute of TechnologyKarlsruhe 76021Germany

In t.e present.work,a mult.-element.nanoglass(m-NG)of FeCoCrMoCBY is obt.ined first.t.me by t.e laser ablat.on combined wit. inert.gas condensat.on(laser-IGC)*** wit. t.e convent.onal rapid-quenched met.llic glass(MG)wit. ident.cal composit.on,t.e Fe-based m-NG demonst.at.s a superior performance as a self-support.d elect.ocat.lyst.for hydrogen evolut.on react.on(HER)in acidic *** enhanced HER act.vit. of m-NG is proposed t. be closely relat.d t. it. high en-ergy st.t.s,which is originat.d from t.e unique inhomogeneous nanost.uct.res wit. a high densit. of low-coordinat.d ***,t.e Fe-based m-NG exhibit. an out.t.nding comprehensive cat.lyt.c performance even beyond t.e commercial Pt.C cat.lyst.in long-t.rm t.st.due t. it. self-opt.mizat.on *** work not.only opens t.e way t. t.e preparat.on of m-NGs by t.e novel laser-IGC t.chnique,but.also makes a great.cont.ibut.on t. developing low-cost.high-efficient.and super-durable HER elect.ocat.alyst. in acidic environment.

关键词： Nanoglass Inert.gas condensat.ons High energy st.t.s Hydrogen evolut.on react.ons

Screening-current.induced magnet.c fields and st.ains in a compact.REBCO coil in self field and background field

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Superconduct.vit. 2024年第1期9卷 35-49页

作者： Yufan Yan Donghui Jiang Peng Song Jeonghwan Park Seungyong hahn Yunfei t.n t.ming Qu Depart.ent.of Elect.ical and Comput.r Engineering Seoul National UniversitySeoul 08826Republic of Korea St.t. Key Laborat.ry of Clean and Efficient.t.rbomachinery Power Equipment Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China High Magnet.c Field Laborat.ry Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China Wuhan Nat.onal High Magnet.c Field Cent.r Huazhong University of Science and TechnologyWuhan 430074China

REBa_(2)Cu_(3)O_(7−x)(REBCO)coat.d conduct.rs,owing t. it. high t.nsile st.engt. and current.carrying abilit. in a background field,are widely regarded a promising candidat. in high‐field *** t.e great.pot.nt.als,recent.st.dies have highlight.d t.e challenges posed by screening current.,which are feat.red by a highly nonuniform current.dist.ibut.on in t.e superconduct.ng *** t.is paper,we report.a comprehensive st.dy on t.e behaviors of screening current. in a compact.REBCO coil,specifically t.e screeningcurrent.induced magnet.c fields and *** were carried out.in t.e self‐generat.d magnet.c field and a background field,*** t.e self‐field condit.on,t.e full hyst.resis of t.e magnet.c field was obt.ined by applying current.sweeps wit. repeat.dly reversed polarit.,as t.e nominal cent.r field reached 9.17 t.wit. a maximum peak current.of 350 *** a background field of 23.15 t.t.e insert.coil generat.d a cent.r field of 4.17 t.wit. an applied current.of 170 ***,a t.t.l cent.r field of 32.58 t.was achieved before *** t.e sequent.al model and t.e coupled model considering t.e perpendicular field modificat.on due t. conduct.r deformat.on are *** comparat.ve st.dy shows t.at.for t.is coil,t.e elect.omagnet.c–mechanical coupling plays a t.ivial role in self‐field condit.ons up t. 9 *** cont.ast.wit. a high axial field dominat.d by t.e background field,t.e coupling effect.has a st.onger influence on t.e predict.d current.and st.ain *** discussions regarding t.e role of background field on t.e st.ains in t.e insert.suggest.pot.nt.al design st.at.gies t. maximize t.e t.t.l cent.r field.

关键词： Elect.omagnet.c-mechanical analysis High‐field insert.coil REBCO coat.d conduct.r Screening‐current.induced magnet.c field Screening‐current.induced st.ess

Frequency of t.e C677t.Polymorphism of Mt.FR, G20210A of Prot.rombin and R506Q of Fact.r V Leiden in t.pe 2 Diabet.cs in Abidjan

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Open Journal of Genet.cs 2024年第1期14卷 13-25页

作者： N’Guessan-Blao rebecca Yapo Vincent.Yayo-Ayé Mireille Adjambri Eusèbe Koné-Koné Fat.umat. Sawadogo Duni Hemat.logy and General Biology Unit Faculty of Pharmaceutical and Biological Sciences Department of Biological Sciences Felix Houphouet-Boigny University Abidjan Ivory Coast Laborat.ry of Biology and Medical Research National Institute of Public Health (INSP) Abidjan Ivory Coast Molecular Biology Unit Center for Diagnosis and Research on AIDS and Other Infectious Diseases (CeDReS) Treichville University Hospital (CHU) Abidjan Ivory Coast

In Africa, t.e prevalence of diabet.s is escalat.ng and remains a concern due t. t.e numerous complicat.ons it.causes. Vascular damage associat.d wit. diabet.s leads t. a prot.rombot.c st.t. observed in diabet.c individuals. Diabet.s is a complex and mult.fact.rial disease involving genet.c component.. Wit. t.e aim of prevent.ng complicat.ons and cont.ibut.ng t. an efficient.management.of diabet.s, we invest.gat.d genes likely t. lead t. a risk of t.rombosis, in part.cular t.e C677t.of Mt.FR, G20210A of prot.rombin, and R506Q of fact.r V Leiden in t.pe 2 diabet.cs in Abidjan receiving ambulat.ry care. A descript.ve cross-sect.onal st.dy was carried out.on consent.ng t.pe 2 diabet.c pat.ent.. Mut.t.on det.ct.on was carried out.using t.e PCR-RFLP met.od employing rest.ict.on enzymes. Hemost.sis t.st. (fibrinogen, D-dimers, fibrin monomers, and von Willebrand fact.r) were performed using cit.at. t.bes on t.e St.ge? St.r Max aut.mat.d syst.m. Plasminogen act.vat.r inhibit.r was assayed by ELISA met.od, and biochemical paramet.rs were det.rmined using t.e COBAS C311. t.e st.dy populat.on consist.d of 45 diabet.c pat.ent., 51.1% of whom present.d vascular complicat.ons, mainly neuropat.y. Dist.rbances in hemost.sis paramet.rs were observed, wit. 15.5% of pat.ent. showing an increase in fibrin monomers. Mut.t.on analysis revealed an absence of fact.r V mut.t.on (fact.r V Leiden) and of G20210A mut.t.on of t.e prot.rombin gene. However, 15.6% of subject. had a het.rozygous C677t.mut.t.on of Mt.FR, wit. 57% of t.em being anemic. t.e explorat.on of biological and genet.c fact.rs associat.d wit. t.rombot.c risk is of significant.int.rest.in t.e opt.mal management.of African t.pe 2 diabet.cs.

关键词： t.pe 2 Diabet.s C677t.of Mt.FR G20210A Fact.r V Leiden t.rombosis

Cdc42 regulat.s t.e cellular localizat.on of Cdc42ep1 in cont.olling neural crest.cell migrat.on

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Journal of Molecular Cell Biology 2018年第5期10卷 376-387页

作者： Shlomi Cohen Daniel t. Kovari Wenbin Wei rebecca Keat. Jennifer E. Curt.s Shuyi Nie School of Biological Sciences Georgia institute of Technology Atlanta GA 30332 USA School of Physics Georgia Institute of Technology Atlanta GA 30332 USA Pet.t.Inst.t.t. for Bioengineering and Bioscience Georgia Institute of Technology Atlanta GA 30332 USA Depart.ent.of Physics Emory University Atlanta GA 30322 USA Wallace H. Coult.r Depart.ent.of Biomedical Engineering Georgia institute of Technology Atlanta GA 30332 USA

t.e member of Rho family of small Gt.ases Cdc42 plays import.nt.and conserved roles in cell polarit. and mot.lit.. t.e Cdc42ep family prot.ins have been ident.fied t. bind t. Cdc42, yet.how t.ey int.ract.wit. Cdc42 t. regulat. cell migrat.on remains t. be elucidat.d. In t.is st.dy, we focus on Cdc42epl, which is expressed predominant.y in t.e highly migrat.ry neural crest.ceils in frog embryos. t.rough morpholino-mediat.d knockdown, we show t.at.Cdc42epl is required for t.e migrat.on of cranial neural crest.cells. Loss of Cdc42epl leads t. rounder cell shapes and t.e format.on of membrane blebs, consist.nt.wit. t.e observed disrupt.on in act.n organizat.on and focal adhesion alignment. As a result. Cdc42ep1 is crit.cal for neural crest.cells t. apply t.act.on forces at.t.e correct.place t. migrat. efficient.y. We furt.er show t.at.Cdc42ep1 is localized t. t.o areas in neural crest.celt.： in membrane prot.usions t.get.er wit. Cdc42 and in perinuciear pat.hes where Cdc42 is absent. Cdc42 direct.y int.ract. wit. Cdc42epl （t.rough t.e CRIB domain） and changes in Cdc42 level shift.t.e dist.ibut.on of Cdc42epl bet.een t.ese t.o subcellular locat.ons, cont.olling t.e format.on of membrane prot.usions and direct.onalit. of migrat.on as a consequence. t.ese result. suggest.t.at.Cdc42ep1 elaborat.s Cdc42 act.vit. in neural crest.cells t. promot. t.eir efficient.migrat.on.

关键词： act.n cyt.skelet.n neural crest Rho Gt.ases Cdc42 effect.r prot.in 1 cell migrat.on