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The Mean Central Cornea Thickness and Associated Factors among Adult Patients Attending Mulago Hospital Eye Clinic Kampala, Uganda

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Open Journal of Ophthalmology 2023年第2期13卷 221-232页

作者： Samia Hersi Ali Anne Ampaire Musika Immaculate Atukunda rebecca claire lusobya John Mukisa Edward Nkurunziza Department of Ophthalmology Makerere University College of Health Sciences Kampala Uganda Department of Ophthalmology Mulago National Referral Hospital Kampala Uganda

Background: The mean central corneal thickness (CCT) values are known to have an influence on intraocular pressure measurement and vary widely with age, sex and ethnicity. Little is known about the pattern of CCT in central Uganda. Aim: To determine the mean central corneal thickness and its associated factors among adult patients attending Mulago Hospital eye clinic, Kampala Uganda. Design and Method: A cross sectional study was done from August to October 2016 on 270 adult patients selected by systemic random sampling. The study included all adult patients who attended the eye clinic during the study period and consented to the study excluding those who had conditions causing abnormal thinning, thickening or irregularity of the cornea. The participants were evaluated by history taking and ocular examination including visual acuity assessment, slit lamp examination, central cornea thickness measurement, intraocular pressure measurement and funduscopy. Data were collected using a pretested questionnaire, entered using Epidata and analyzed by STATA11.0. Results: Of the 270 patients examined, 61% were female, 39% male, the mean age being 42 years ranging from 18 to 96 years. The mean central corneal thickness for both eyes was 539.3 (SD ± 41.65 μm) ranging from 332 μm to 701 μm and mean intraocular pressure was 15 (SD ± 5.34) mmHg. Gender, ethnicity, IOP, glaucoma, hypertension, diabetes, refractive error, were not statistically significantly associated with central cornea thickness. However central cornea thickness was statistically significantly associated with systolic blood pressure (r = -0.24, p = 0.025) and age (p = 0.002). A one-year increase in age reduced the mean central cornea thickness by 0.54 μm. Conclusion: The average CCT of Ugandan adult population was 539.3 ± 41.65 μm which falls in the category of normal central cornea thickness. Central corneal thickness reduced with increasing age and increasing systolic blood pressure.

关键词： Central Cornea Thickness Intraocular Pressure Fundus

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The Mean Central Cornea Thickness and Associated Factors among Adult Patients Attending Mulago Hospital Eye Clinic Kampala, Uganda

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Open Journal of Ophthalmology（眼科学期刊） 2023年第2期

作者： Samia Hersi Ali Anne Ampaire Musika Immaculate Atukunda rebecca claire lusobya John Mukisa Edward Nkurunziza

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Associations of self-reported and device-assessed physical activity with fatigue,quality of life,and sleep quality in adults living with and beyond cancer

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Journal of Sport and Health Science 2023年第6期12卷 664-673,F0003页

作者： Phillippa Lally Natalie Ella Miller claire Lawrence rebecca J Beeken Abigail Fisher Department of Behavioural Science and Health University College LondonLondon WC1E 6BTUK Department of Psychology University of SurreyGuildford GU27XHUK Leeds Institute of Health Sciences Leeds LS29NLUK

Background Greater physical activity is associated with improved outcomes in people living with and beyond ***,most studies in exercise oncology use self-reported measures of physical *** have explored agreement between self-reported and device-based measures of physical activity in people living with and beyond *** study aimed to describe physical activity in adults affected by cancer across self-reported and device-assessed activity,to explore levels of agreement between these measures in terms of their utility for categorizing participants as meeting/not meeting physical activity guidelines,and to explore whether meeting guidelines is associated with fatigue,quality of life,and sleep *** A total of 1348 adults living with and beyond cancer from the Advancing Survivorship Cancer Outcomes Trial completed a survey assessing fatigue,quality of life,sleep quality,and physical *** Godin-Shephard Leisure-Time Physical Activity Questionnaire was used to calculate a Leisure Score Index(LSI)and an estimate of moderate-to-vigorous physical activity(MVPA).Average daily steps and weekly aerobic steps were derived from pedometers worn by *** The percentage of individuals meeting physical activity guidelines was 44.3%using LSI,49.5%using MVPA,10.8%using average daily steps,and 28.5%using weekly aerobic ***(Cohen'sκ)between self-reported and pedometer measures ranged from 0.13(LSI *** daily steps)to 0.60(LSI ***).After adjusting for sociodemographic and health-related covariates,meeting activity guidelines using all measures was associated with not experiencing severe fatigue(odds ratios(ORs):1.43–1.97).Meeting guidelines using MVPA was associated with no quality-of-life issues(OR=1.53).Meeting guidelines using both self-reported measures were associated with good sleep quality(ORs:1.33–1.40).Conclusion Less than half of all adults affected by cancer are meeting physical activity guidelines,

关键词： Cancer survivorship Fatigue Physical activity Quality of life SleepTagedAPTARAEnd

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Evaluation of Pedestrian–Train Fatalities in the State of Maryland: A 5‑Year Retrospective Study

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Journal of Forensic Science and Medicine 2020年第4期6卷 135-139页

作者： Elvira Carias claire Hammerschmidt Taylor Hall Xiang Zhang rebecca Phipps Ling Li Office of the Chief Medical Examiner State of MarylandBaltimoreMarylandUSA Master of Science in Forensic Medicine Program Graduate Schoolat University of Maryland BaltimoreBaltimoreMarylandUSA

Few studies have been done on the incidences of train-related pedestrian fatalities throughout the United States,with no previous studies reported in the State of Maryland.A retrospective study was conducted at the statewide medical examiner’s office in Maryland to evaluate the characteristics of train-related pedestrian fatalities from 2014 to *** aim of the study was to analyze circumstances of deaths through the medicolegal death investigation and postmortem examination findings,including toxicological study,to help identify epidemiological characteristics of pedestrian–train‑related fatalities.A total of 48 pedestrian-train deaths were *** the 48 cases identified,21 deaths(43.75%)were determined to be accident,20 deaths(41.67%)were suicide,and 7 deaths(14.58%)whose manner of death could not be *** the 21 accidental victims,17 were male and 4 were female(M:F ratio=4.3:1),11(52.38%)were white,6(28.57%)African American,and 4 Hispanic(19.05%),with age ranging from 16 to 58 years(mean age=35).Of the 20 suicide victims,17 were males and 3 females(M:F ratio=5.7:1),16(80%)were white,2(10%)African American,and 2(10%)Hispanic,with age ranging from 22 to 60 years(mean age=40).The majority of accidents occurred during weekday evening rush hours between 4:00 pm and 7:00 pm,while the suicides showed no specific time *** specific peak for seasons of year was found in suicides or *** toxicological studies showed that 52.38%(11/21 cases)of accidental victims were positive for alcohol and 30%(6/20 cases)of suicide victims were positive for *** of death could not be determined in 7 cases because of unclear circumstances of *** death scene investigation and complete postmortem examination,including comprehensive toxicological testing,is very important in all train-related pedestrian *** the manner of death can directly affect the outcome of civil ligation and dispersal of insurance ***

关键词： Pedestrian train accident suicide forensic investigation

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Classification, diagnosis, and management of conjunctival lymphoma

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Eye and Vision 2019年第1期6卷 175-190页

作者： rebecca E.Tanenbaum Anat Galor Sander R.Dubovy Carol L.Karp Department of Ophthalmology Bascom Palmer Eye InstituteUniversity of Miami Miller School of Medicine900 NW 17th St.MiamiMiamiFL 33136USA

Lymphoma is a malignant lymphoproliferative tumor that can involve the *** 5–15%of all extranodal lymphomas are found in the ocular adnexal region,with approximately 25%of those involving the ***-eight percent of conjunctival lymphomas arise from *** most common subtype of conjunctival lymphoma is extranodal marginal zone lymphoma(80%),followed by follicular lymphoma(8%),diffuse large B-cell lymphoma(3%)and mantle cell lymphoma(3%).Natural killer and T cells(NK/T)are rare causes of *** most conjunctival lymphomas are localized to the ocular adnexa at the time of presentation,systemic examination and management are of key importance in the long-term care of the *** review outlines the classification,etiology,presentation,diagnosis,and management of conjunctival *** novel use of high resolution optical coherence tomography,both as a diagnostic tool and as a means for ongoing evaluation during treatment,is *** options discussed include external beam radiation,chemotherapy,immunotherapy,antibiotic therapy,and combination *** investigation of the etiology and pathogenesis of conjunctival lymphoma is expected to reveal opportunities for innovative and individualized therapeutic *** between multiple disciplines is key in the advancement of the field.

关键词： Conjunctiva Conjunctival tumor Extranodal marginal zone lymphoma Lymphoma Optical coherence tomography Salmon patch

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针灸治疗慢性头痛的初级保健:大样本、实用的随机试验

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英国医学杂志中文版 2005年第2期8卷 89-92页

作者： Andrew J Vickers rebecca W Rees Catherine E Zollman Rob McCarney claire Smith Nadia Ellis Peter Fisher Robbert Van Haselen 宋军 Integrative Medicine ServiceBiostatistics Service Memorial Sloan-Kettering Cancer Center1275 York AvenueNYNY 10021 assistant attending research methodologist Evidence for Policy and Practice Information and Co-ordinating Centre (EPPI-Centre)Social Science Research Unit Institute of EducationLondon WC1H 0NS research officer MontpelierHealth Centre Department of Psychological MedicineImperial College London London W2 1PD research officer Academic RheumatologyWeston Education Centre King's CollegeLondon SE5 9RJ senior trials coordinator Department of Health and Social SciencesCoventry University Coventry CV1 5FB lecturer Royal London Homeopathic HospitalLondon W1W 5PB director of research Royal London Homeopathic Hospital London W1W 5PB deputy director of research

目的与“不用针灸”对比,确定“使用针灸”的治疗方法对慢性头痛患者的头痛、健康状况及无病时间的影响。设计随机对照试验。试验场所英格兰和威尔士的开业医生诊所。受试对象 401位慢性头痛患者,主要是偏头痛患者。干预患... 详细信息

目的与“不用针灸”对比,确定“使用针灸”的治疗方法对慢性头痛患者的头痛、健康状况及无病时间的影响。设计随机对照试验。试验场所英格兰和威尔士的开业医生诊所。受试对象 401位慢性头痛患者,主要是偏头痛患者。干预患者被随机分配进入针灸治疗组(在 3个月内接受12次针灸治疗)和对照组(接受常规治疗)。主要结果测定指标治疗前、治疗后3个月及12个月对头痛积分,SF-36健康状况及用药量进行评估。每3个月对治疗方法作1次评估。头痛积分即判定疗效的主要终点指标。结果针灸组治疗后12个月的头痛积分(针灸组161例患者,平均头痛积分为16．2,标准差 13．7,比治疗前减少34％)比对照组低(对照组140 例患者,平均头痛积分为22．3,标准差17．0,比治疗前减少16％)。两种方法调整后的差异为4．6 (95％可信区间为2．2-7．0;P=0．0002)。对于包含缺失数据的灵敏度分析,该结果也是肯定的。针灸组的患者每年少头痛22(8-38)天。尽管达到统计学差异的项目仅有生理功能、精力和健康改变等,SF-36的资料也有利于针灸组。与对照组相比,针灸组的患者减少了15％的服药量(P=0．02), 减少了25％的就诊量(P=0．10),同时减少15％的病休时间(P=0．2)。结论针灸在初级保健中用于治疗慢性头痛, 特别是偏头痛,可以产生与临床相关的持久益处。应当考虑扩大英国国家医疗保险体系中针灸治疗的范围。

关键词：慢性头痛针灸治疗初级保健随机试验大样本 SF-36 随机对照试验医疗保险体系治疗方法健康状况偏头痛患者灵敏度分析统计学差异对照组治疗前开业医生受试对象常规治疗随机分配测定指标终点指标可信区间

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地球早期地幔的冷凝结晶始于核幔边界或下地幔

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国际地震动态 2013年第8期34卷 5-5页

作者： claire W Thomas Qiong Liu Carl B Agee Paul D Asimow rebecca A Lange 刘学中国科学院国家科学图书馆兰州分馆/中国科学院资源环境科学信息中心

JGR（Journal of Geophysical Research：Solid Earth）于2012年10月12日，发表了题为“Multi—technique equation of state for Fe2Si04 melt and the density of Fe—bearing silicate melts from 0 to 161 GPa”的文章指出，地球早... 详细信息

关键词：核幔边界下地幔结晶冷凝早期地球 Solid Multi

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药剂车

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世界建筑导报 2021年第5期36卷 48-48页

作者： Emilie Taylor Welty Nick Jenisch Elizabeth Bateman Jeremy Baudy Anna Deeg claire Divito rebecca Dunn Adrian Evans Danelle Martin Danielle Scheeringa Bhumika Shirole Zach Speroni James Rennert Dana Ridenour 不详

设计如何开启对话,并作为宣传和教育的工具?药剂车,许多移动的装有药剂的车,试图让我们想象没有监狱的景象。美国有220万犯人,约9万人无限期单独监禁。疏离、人性丧失、绝望、迷失方向、偏执、自杀意念,单独监禁带来的无法弥补,近乎毁... 详细信息

设计如何开启对话,并作为宣传和教育的工具?药剂车,许多移动的装有药剂的车,试图让我们想象没有监狱的景象。美国有220万犯人,约9万人无限期单独监禁。疏离、人性丧失、绝望、迷失方向、偏执、自杀意念,单独监禁带来的无法弥补,近乎毁灭的影响远不止这些。囚犯药剂车从受大规模监禁荼毒最深的社区采取植物,转化为药。药剂师根据交谈或书信为全美国单独监禁犯人提供天然药物、茶、酊剂、蒸汽和药膏。

关键词：单独监禁自杀意念天然药物监狱药剂师犯人

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