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Role of ammonia in predicting the outcome of patients with acuteon- chronic liver failure

World Journal of Clinical Cases 2021年第3期9卷 552-564页

作者： Stefan Chiriac Carol Stanciu Camelia Cojocariu Ana-Maria Singeap Catalin Sfarti Tudor Cuciureanu Irina Girleanu razvan Alexandru Igna Anca Trifan Department of Gastroenterology “Grigore T.Popa”University of Medicine and PharmacyIasi 700115Romania Institute of Gastroenterology and Hepatology "St.Spiridon"Emergency HospitalIasi 700111Romania Intensive Care “Grigore T.Popa”University of Medicine and PharmacyIasi 700115Romania

BACKGROUND High venous ammonia(VA)values have been proven to be a part of the mechanism of hepatic encephalopathy in patients with liver cirrhosis(LC)as well as acute ***,VA has been associated with poor prognosis and high mortality in these clinical ***,the role of ammonia in acuteon-chronic liver failure(ACLF)has not yet been clearly *** To assess the role of VA in predicting the outcome of cirrhotic patients with ACLF in a tertiary care *** We performed a retrospective observational study including consecutive patients with LC hospitalized for acute non-elective indications such as ascites,hepatic encephalopathy(HE),upper gastrointestinal bleeding,or bacterial infections that fulfilled the Asian Pacific Association for the Study of the Liver(APASL)criteria for *** study was conducted in“***”University Hospital,Iasi,Romania,a tertiary care center,between January 2017 and January *** APASL ACLF Research Consortium(AARC)score was calculated and ACLF grade was established ***-haven classification was used for *** analysis was performed using IBM SPSS version *** Four hundred and forty-six patients were included,aged 59(50-65)years,57.4%***-Pugh,model for end-stage liver disease(MELD)and AARC scores were 11(10-12),19.13±6.79,and 7(6-8),respectively.66.4%had ACLF grade I,31.2%ACLF grade II,and 2.5%ACLF grade *** was diagnosed in 83.9%,34%grade I,37.2%grade II,23.5%grade III,and 5.3%grade *** mortality was 7.8%.VA was 103(78-148)μmol/*** operating characteristic analysis showed good accuracy for the prediction of in-hospital mortality for the AARC score[Area under the curve(AUC)=0.886],MELD score(AUC=0.816),VA(AUC=0.812)and a fair accuracy for the Child-Pugh score(AUC=0.799).Subsequently,a cut-off value for the prediction of mortality was identified for VA(152.5μmol/L,sensitivity=0.706,1-specificity=0.190).Univariate analysis found acute kidney in

关键词： Venous ammonia Hepatic encephalopathy Acute-on-chronic liver failure Asian Pacific Association for the Study of the Liver Acute-on-chronic Liver Failure Research Consortium score Cirrhosis Mortality

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The Relationship Between the Circular Economy and Sustainable Waste Management in European Union

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Journal of Business Administration Research 2021年第1期4卷 37-44页

作者： Marcuta Liviu Panait razvan Marcuta Alina University of Agronomic Sciences and Veterinary Medicine of Bucharest 59Marasti BIdDistrict 1Bucharest011464Romania

Modern life has contributed both to increasing living standards,increasing comfort and the development of society,but also to increasing the amount of waste that suffocates the planet and threatens the existence of present and future *** the solutions that are sought and that are included in various programs and policies,the concept of circular economy is one that is increasingly discussed when talking about the sustainable development of *** circular economy implies a reduction of the natural resources consumed due to both recycling and their fair *** the *** the foundations have been laid for policies aimed at waste management to ensure the application of the principles of the circular *** the importance that the quantification of the indicators for implementing the circular economy have on the elaboration of more efficient policies,but also on the determination of the degree of implementation of this concept,in this paper we intend to analyze the evolution of these indicators from 2010-2019,in the European Union using a customized version of the DPSIR *** analysis led us to the conclusion that although important steps have been taken towards the transition to the circular economy,there are still many aspects that need to be improved in order to achieve the proposed objectives through European policies.

关键词： Circular economy Waste Sustainability European policies

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Comparative Analysis of Sonar Heads Drive Systems

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Journal of Energy and Power Engineering 2012年第9期6卷 1453-1460页

作者： Ion Voncila razvan Buhosu Elena Voncila Department of Control Systems and Electrical Engineering "Dunarea de Jos " University of Galati Galati 800008 Romania

This paper is dealing with a comparative analysis, from technical point of view of the solutions with the highest potentiality utilized in sonar heads drives. Even though the use of DC servomotors is a convenient solution for most customers, from some modem analysis criteria points of view, this type of drive system has a low reliability and a greater impact on the environment, compared to AC servomotors. From this class of AC servomotors, high behaviors, in such an application, have stepper motors and electronically commutated motor （brushless DC）. That is why, analysis in this paper, balances these two classes of AC servomotors. The systems performed are analyzed in Matlab/Simulink and PowerSim environments.

关键词： Synchronous servomotors position incremental control systems brushless DC motors sonar heads drives.

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Assessment of Air Pollution,by the Urban Traffic,in University Campus of Bucharest

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Journal of Environmental Protection 2017年第8期8卷 884-897页

作者： razvan Stefan Popescu Lelia Letitia Popescu Technical University of Civil Engineering of Bucharest BucharestRomania

This study aims to measure traffic-related air pollution of vehicles with internal combustion, the main source of emissions of BTEX, organic compounds and NOx, NO2, NO, O3, CO, SO2, PM10 and PM2.5, inorganic compounds, in three sites of the University campus, surrounded by residential areas. According to the University data, around 8000 students are being exposed daily to the measured level of pollution, in all 3 studied places of campus. A mobile laboratory was used, which continuously measures above mentioned pollutants and mete-orological parameters. The diurnal variation of BTEX, in a sunny and rainy day showed two peaks of BTEX concentration in the morning and evening. In the rainy days, the non-polar (hydrophobic) compounds as BTEX are mechanically trained by rain into the ground, where either they enter into the groundwater, or volatilized and re-enter in the air. Particulate matter such as PM10 and PM2.5 is, in a large part, carried by the rain into the soil. The polar compounds (hydrophilic, NOx, SO2) dissolves in the rainwater and are absorbed in the soil (increasing soil acidity) and evaporated towards the clouds (leading to acid rain). In our study, BTEX compounds removed by the rain varied between 62% - 75%, NOx and SO2, 80% and 77% respectively. Particulate matters were washed out up to 68% for PM10, and 42% for PM2.5. In the sunny days the air pollution with measured concentrations of O3 (121.66 ± 7.02, 123.56 ± 4.89 μg/m3) remained for 7 hours close to the limit value (120 μg/m3). The maximum of solar radiation, with corresponding low concentrations in NOx and xylene, corresponds to photochemical reactions in the atmosphere, generating photochemical smog. In a sunny day and high traffic, we found the maximum value 5.4 μg/m3 for benzene, for 30 min., a known human carcinogen, exceeding the annual limit value de 5 μg/m3. The average background, from benzene, in three University campuses daily visited by around 8000 students was 0.97 μg/m3, exposed to 1

关键词： University Campus Outdoor Air Quality BTEX Mobile Laboratory PM10 PM2.5

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Relationship between plasma adipokines, inflammation, insulin resistance and subclinical atherosclerosis in newly diagnosed type 2 diabetes

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Journal of Diabetes Mellitus 2011年第2期1卷 17-25页

作者： razvan Vasilescu Silvi Ifrim Constantin Ionescu-Tirgoviste 不详

Background: The aim of this study was to investigate the occurrence of subclinical atherosclerosis, evaluated by carotid artery intima-media thickness (CIMT) in subjects with newly diagnosed type 2 diabetes. Methods: A total of 167 subjects, 50 newly diagnosed type 2 diabetic subjects and 117 non-diabetic subjects were included in the study. Obese and overweight newly diagnosed type 2 diabetic patients were matched for age and BMI with obese and overweight non-diabetic subjects. Only postmenopausal women were selected. The following biomarkers were analyzed: fasting glucose, HbA1c, fasting insulin, fasting proinsulin, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, adiponectin, leptin, hs-CRP, urine albumin/creatinine ratio. 75 g oral glucose tolerance test was performed in all subjects. Ultrasound imaging was used to evaluate IMT of the common carotid artery. Results: CIMT was greater in newly diagnosed type 2 patients compared to non-diabetic subjects. When analyzed by BMI, the difference regarding CIMT between diabetic and non-diabetic subjects was significant only in overweight subjects, in both sexes. In univariate analysis in men with newly diagnosed type 2 diabetes, CIMT was positively correlated with age, SBP, triglycerides, leptin and negatively correlated with HDL-cholesterol and in women CIMT was positively correlated with SBP and leptin. Independent determinants of CIMT in patients with newly diagnosed type 2 diabetes were in men age (β = 0.556, p = 0.0028) and log leptin (β = 0.393, p = 0.049) and in women systolic blood pressure (β = 0.48, p = 0.026). Conclusions: Subclinical atherosclerosis is present in newly diagnosed type 2 diabetic subjects. Body fat accumulation in men and hypertension in postmenopausal women have a primary role in increase carotid intima-media thickness.

关键词： Newly Diagnosed Type 2 Diabetes Atheroscleorsis Common Carotid Artery Intima-Media Thickness

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基于落锤式弯沉仪评定神华包神重载铁路路基性能状态研究

基于落锤式弯沉仪评定神华包神重载铁路路基性能状态研究

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作者： Ionut-razvan Georgescu 哈尔滨工业大学

学位级别：硕士

众所周知,铁路是客运、货运最可靠、最节能的交通运输方式。目前,铁路行业正迅猛发展,因此所研究的课题为当前热点。铁路系统主要性能的传统监测方法不能满足近来工程建设的要求。建设过程和保养过程中花费高是铁路运输主要的缺点之一... 详细信息

众所周知,铁路是客运、货运最可靠、最节能的交通运输方式。目前,铁路行业正迅猛发展,因此所研究的课题为当前热点。铁路系统主要性能的传统监测方法不能满足近来工程建设的要求。建设过程和保养过程中花费高是铁路运输主要的缺点之一。而且,对采集铁轨系统精确信息新技术的需求愈加迫切。作为典型的岩土结构,铁路路基是否方便施工,应力分布是否均匀,取决于道渣和基床的质量。传统的铁路系统包括钢轨、扣件、枕木、道渣和路基等部件,组成一个抵抗各种交通和气候作用的结构系统。具有较大轴重的高速铁路的使用,需要对移动列车传递给轨道系统的荷载和路基各土层应力、应变和变形的传递方式有一个更好的理解。为了更好的理解整个铁轨系统的反应,本文建立了正确反映上部结构和下部基础的数值模型。为了确定列车荷载对铁路轨系统各组件的影响,需要准确的确定路基土层弹性参数。文中对锤式弯沉仪的使用进行了介绍,并对奥西斯铁路K33断面和塔韩铁路DK1断面的测试结果进行了阐述。此外,对其他测试场地得到的落锤式弯沉仪测试位移数据进行反演分析获得路基土的材料特性。数值分析的结果由设置在距落锤式弯沉仪测试荷载施加点不同距离的传感器位移表示。为了保证不超过某个误差百分数,数值分析得到的峰值位移要跟实测位移进行对比。数值计算得到的峰值位移分别是200.049μm,154.497μm,144.023μm,113μm,79.925μm,66.7μm和56.5μm,验证了所建模型的正确性及其重要性。文章最后使用与前文相同的路基土弹性模量进行动力分析,输出了铁路轨道系统各部件应力、加速度,重点对路基三层土进行了分析。研究结果表明,不同速度的列车,路基动应力和加速度剧烈波动。随着时间和距离的增加,动应力、加速度明显降低。两个数值分析对落锤式弯沉仪测试得到的峰值位移做了很好的概述,对路基土层中动应力和加速度有更好理解。

关键词：重载铁路路基性能评价落锤式弯沉仪测试弹性模量动应力

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建立三角形几何不等式的一个一般方法

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数学通讯（教师阅读） 2003年第1期17卷 27-28页

作者： razvan Alin Satnoianu 郭要红安徽师范大学安徽241000

1引言本文的目的是给出一个关于三角形的一大类几何不等式的简单但又强有力的证明原理,方法是将一般三角形的情形化为等腰三角形.

关键词：三角形几何不等式证明

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Utilization of Hot Spotting to Identify Community Needs and Coordinate Care for High-Cost Patients in Memphis, TN

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Journal of Geographic Information System 2014年第1期6卷 23-29页

作者： Teresa Cutts Edward Rafalski Cori Grant razvan Marinescu Methodist Le Bonheur Healthcare University of Memphis School of Public Health Memphis USA Methodist Le Bonheur Healthcare University of Memphis School of Public Health Memphis USA University of Tennessee Health Science Center Knoxville USA University of Illinois School of Public Health Chicago USA Qsource & University of Memphis School of Public Health Memphis Memphis USA Wake School of Medicine Division of Public Health Sciences Winston Salem USA

In 2006, Methodist Le Bonheur Healthcare (MLH) created the Congregational Health Network (CHN, TM pending) which works closely with clergy in the most under-served zip codes of the city to improve access to care and overall health status of the population. To best coordinate CHN resources around high-utilization and address the largest health needs in the community, MLH applied hot spotting and geographic information system (GIS) spatial analysis techniques. These techniques were coupled with the community health needs assessment process at MLH and qualitative, participatory research findings captured in collaboration with church and other community partners. The methodology, which we call “participatory hot spotting,” is based upon the Camden Model, which leverages hot spotting to assess and prioritize community need in the provision of charity care, but adds a participatory, qualitative layer. In this study, spatial analysis was employed to evaluate hospital-based inpatient and outpatient utilization and define costs of charity care for the health system by area of residence. Ten zip codes accounted for 56% of total system charity care costs. Among these, the largest zip code, as defined by a percentage of total charity costs, contributed 18% of the inpatient utilization and 17% of the cost. Further, this zip code (38109) contributed 69% of the inpatient and 76% of the outpatient charity care volume and accounted for 75% of inpatient and 76% of outpatient charity care costs for the system. These findings were combined with grassroots intelligence that enabled a partnership with clergy and community members and Cigna Healthcare to better coordinate care in a place-based population health management strategy. Presentations of the analytics have subsequently been made to HHS and the CDC, referred to by some as the “Memphis Model”.

关键词： Hot Spotting CHNA (Community Health Needs Assessment) Congregational Health Network (CHN) Memphis Model Health Disparities

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Ultrashort Bessel beam photoinscription of Bragg grating waveguides and their application as temperature sensors

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Photonics Research 2019年第7期7卷 121-129页

作者： Guodong Zhang Guanghua Cheng Manoj K.Bhuyan Ciro D'Amico Yishan Wang razvan Stoian Laboratoire Hubert Curien UMR 5516 CNRSUniversite de LyonUniversite Jean Monnet42000 Saint EtienneFrance State Key Laboratory of Transient Optics and Photonics Xi'an Institute of Optics and Precision MechanicsCASXi'an 710119China School of Electronics and Information Northwestern Polytechnical UniversityXi'an 710072China Academy of Scientific and Innovative Research CSIR-Central Scientific Instruments OrganizationChandigarh 160030India Optical Devices and Systems Division CSIR-Central Scientific Instruments OrganizationChandigarh 160030India

Ultrashort pulsed Bessel beams with intrinsic nondiffractive character and potential strong excitation confinement down to 100nm can show a series of advantages over Gaussian beams in fabricating efficient Bragg grating waveguides(BGWs).In this work, we focus on parameter management for the inscription of efficient BGWs using the point-by-point method employing Bessel *** to their high aspect ratio, the resulting one-dimensional void-like structures can section the waveguides and interact efficiently with the optical modes. Effective first-order BGWs with low birefringence can then be fabricated in bulk fused silica. By controlling the size and the relative location of grating voids via the Bessel pulse energy and scan velocities, the resonant behaviors of BGWs can be well regulated.A high value of 34 dB for 8 mm length is achieved.A simple predictive model for BGWs is proposed for analyzing the influences of processing parameters on the performance of BGWs. The technique permits multiplexing several gratings in the same *** to eight grating traces were straightforwarcliy inscribed into the waveguide in a parallel-serial combined mode, forming the multiplex *** an application, the multiplex BGW sensor with two resonant peaks is proposed and fabricated for improving the reliability of temperature detection.

关键词： photoinscription waveguides temperature detection

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Numerical Analysis of an Industrial Polycrystalline Silicon Photovoltaic Module Based on the Single-Diode Model Using Lambert W Function

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Journal of Power and Energy Engineering 2019年第7期7卷 29-38页

作者： Mihai razvan Mitroi Valerica Ninulescu Laurentiu Fara Dan Craciunescu University Politehnica of Bucharest BucharestRomania Academy of Romanian Scientists BucharestRomania

It is adopted the single-diode solar cell model and extended for a PV module. The current vs. voltage (I-V) characteristic based on the Lambert W-function was used. The estimation parameters for the simulation approach of the photovoltaic (PV) module make use of Levenberg-Marquardt method. It was considered an industrial polycrystalline silicon photovoltaic (PV) module and the simulated results were compared with the experimental ones extracted from a specific datasheet. The I-V characteristic for the analysed PV module and its maximum output power are investigated for different operating conditions of incident solar radiation flux and temperature, as well as parameters related to the solar cells material and technology (series resistance, shunt resistance and gamma factor). The analysis gives indications and limitations for design and optimization of the performance for industrial PV modules. This study can be implemented in any type of PV module.

关键词： Single-Diode Model Electrical Modeling I-V Characteristic Numerical Analysis Industrial PV Module Performance

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