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miRACA： A database for miRNAs associated with cancers and age related disorders （ARD）

Frontiers in Biology 2018年第1期13卷 36-50页

作者： razia rahman Lokesh Kumar Gahlot Yasha Hasija Department of Biotechnology Delhi Technological University Shahbad Daulatpur Main Bawana Road Delh# l l O042 India

BACKGROUND： With the given diversity and abundance of several targets of miRNAs, they functionally appear to interact with several elements of the multiple cellular networks to maintain physiologic homeostasis. They can function as tumor suppressors or oncogenes, whose under or overexpression has both diagnostic and prognostic significance in various cancers while being implicated as prospective regulators of age-related disorders （ARD） as well. Establishing a concatenate between ARD and cancers by looking into the insights of the shared miRNAs may have a practical relevance. METHODS： In the present work, we performed network analysis of miRNA-disease association and miRNA-target gene interaction to prioritize miRNAs that play significant roles in the manifestation of cancer as well as ARD. Also, we developed a repository that stores miRNAs common to both ARD and cancers along with their target genes. RESULTS： We have comprehensively curated all miRNAs that we found to be shared in both the diseases in the human genome and established a database, miRACA （Database for microRNAs Associated with Cancers and ARD） that currently houses information of 1648 miRNAs that are significantly associated with 38 variants supported with pertinent data. It has been made available online at http：//***/miraca/for easy retrieval and utilization of data by the scientific community. CONCLUSION： To the best of our knowledge, our database is the first attempt at compilation of such data. We believe this work may serve as a significant resource and facilitate the analysis of miRNA regulatory mechanisms shared between cancers and ARD to apprehend disease etiology.

关键词： miRNA cancer age related disorders (ARD) target genes database

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New solitary wave in shallow water,plasma and ion acoustic plasma via the GZK-BBM equation and the RLW equation

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Propulsion and Power Research 2017年第1期6卷 49-57页

作者： Harun-Or Roshid Md.Mamunur Roshid Nizhum rahman Mst.razia Pervin Department of Mathematics Pabna University of Science and TechnologyPabna 6600Bangladesh Department of Natural Sciences Daffodil International UniversityDhaka 1207Bangladesh Department af Mathematics Mawlana Bhashani Science and Technology UniversitySantnsh 1902Bangladesh

This work obtains the disguise version of exact solitary wave solutions of the generalized(2+1)-dimensk>nal Zakharov-Kuznetsov-Benjamin-Bona-Mahony and the regularized long wave equation with some free parameters via modified simple equation method(MSE).Usually the method does not give any solution if the balance number is more than one,but we apply MSE method successfully in different way to carry out the solutions of nonlinear evolution equation with balance number *** some graphical results of the velocity profiles are presented for different values of the material *** is shown that this method,without help of any symbolic computation,provide a straightforward and powerful mathematical tool for solving nonlinear evolution equation.

关键词： The modified simple equation method Exact traveling wave solution Generalized Zakharov-Kuznetsov-Benjamin-Bona-Mahony(GZK-BBM) The regularized long wave equation Balance number Nonlinear evolution equations(NLEEs)

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Green and Efficient Oxidation of Octanol by Iron Oxide Nanoparticles Supported on Activated Carbon

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Modern Research in Catalysis 2015年第1期4卷 28-35页

作者： Mohammad Sadiq razia Aman Saddam Hussain Muhammad Abid Zia Najeeb Ur rahman Mohammad Saeed Department of Chemistry University of Malakand Khyber Pakhtunkhwa Pakistan Department of Chemistry University of Education Attock Campus Attock Pakistan Department of Chemistry GC University Faisalabad Pakistan

Iron oxide nanoparticles were synthesized by precipitation method and supported on activated carbon. The catalyst thus obtained was characterized by various physicochemical techniques, and used for the liquid phase dehydrogenation/oxidation of octanol in a batch reactor at various temperatures in the range 30 °C - 60 °C. Maximum conversion of octanol to octanal was attained at 60°C in 30 min. However, with longer reaction time, the selectivity of the catalyst was found to change in favor of octene as a product. The catalyst could be recovered and reused multiple times without any decline in its catalytic performance.

关键词： Liquid Phase Oxidation Dehydration Octanol

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Yield Gap of Stress Tolerant Rice Varieties Binadhan-10 &Binadhan-11 in Some Selected Areas of Bangladesh

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Agricultural Sciences 2019年第11期10卷 1438-1452页

作者： razia Sultana Md. Habibur rahman Md. Rashidul Haque Md. Mohsin Ali Sarkar Syful Islam Bangladesh Institute of Nuclear Agriculture (BINA) Mymensingh Bangladesh

Binadhan-10 & Binadhan-11 are climate smart stress tolerant high yielding rice varieties (yield > 4 t⋅ha−1) have saline tolerant EC up to 12 ds/m and submergence tolerant up to 20 - 25 days capacity. The present study was an attempt to analyze the yield gap of stress tolerant varieties Binadhan-10 & Binadhan-11 in some selected areas of Bangladesh. The objectives of the study were: 1) to estimate the yield gap of Binadhan-10 &-11 growers among the study areas;2) to identify the factors affecting the yield of these variety;and 3) to suggest some policy guidelines to minimize the yield gap. The study was conducted in eight Binadhan-10 & Binadhan-11 growing areas in Bangladesh. In this study, four districts namely Satkhira, Khulna, Barishal, and Cox’s Bazar were used for Binadhan-10 and Mymensingh, Jamalpur, Sherpur and Sunamgonj were taken for Binadhan-11. It is based on primary level data from eight sub-districts among the study areas. A total of 240 farmers were randomly selected (30 from each location) to collect the data with a pre-designed questionnaire. Farmer were grouped according to saline affected and not-affected for saline tolerant variety Binadhan-10 and not affected, affected (1 - 10 days) and highly affected (10 - 20 days) for submergence tolerant rice variety Binadhan-11 to identify existing yield gap. Tabular as well as Zandstra method were applied for analysis the data. The study also found factors affecting the gap and some policy guidelines to minimize the gap.

关键词： Stress Tolerant Saline Tolerant Submergence Tolerant Rice Yield Yield Gap

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Quality Assessment of Surface and Drinking Water of Nakla Paurosova, Sherpur, Bangladesh

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Advances in Microbiology 2019年第8期9卷 703-727页

作者： Sourav Sarker Shahin Mahmud razia Sultana Ritu Biswas Partha Protim Sarkar Md. Abul Munayem Nur-E-Alam Md. Rayhan Ali Muhammad Wasim Md. Firoz Ali Md. Omar Faruque Fatematuz Zuhura Evamoni Department of Biotechnology and Genetic Engineering Mawlana Bhashani Science and Technology University Tangail Bangladesh Department of Biotechnology and Genetic Engineering Noakhali Science and Technology University Noakhali Bangladesh Department of Biotechnology and Genetic Engineering Bangabandhu Sheikh Mujibur Rahman Science and Technology University Gopalganj Bangladesh Department of Biotechnology Bangladesh Agricultural University Mymensingh Bangladesh

Water is one of the most vital elements of ecosystem and human being, but unfortunately nowadays, the pollution of surface and drinking water is an alarming problem. The present work deals with the assessment of physicochemical and bacteriological profile of several pond, jar and tube-well water samples to ensure its suitability for using and drinking. Total 30 samples were randomly selected and collected from Nakla Paurosova of Sherpur district by following the standard procedure. Bacteriological analysis was carried out by following the standard bacteriological methods. Most of the surface water sampling points were polluted by dumping of waste, cattle wash and were not suitable for drinking or other domestic purposes. Among three heavy metals, only Iron was detected in six tube-well water samples, one was also positive to arsenic, rest of the water bodies were negative to all of these metals. In case of most of the water bodies, different physicochemical properties were below standard limit. In pond water, the Total Viable Count (TVC) ranged from 2.7 × 107 cfu/100ml to 4.4 × 1015 cfu/100ml and Total Coliform Count (TCC) were 3.4 × 105 cfu/100ml to 4.8 × 1013 cfu/100ml, where the mean concentration of Heterotrophic Plate Count (HPC) was 2.4 × 105 cfu/100ml and 1.8 × 105 cfu/100ml in jar and tube-well water respectively. On the other hand, the Total Coliform Count of supply water was 33 cfu/100ml and tube-well water was 14 cfu/100ml. Fecal coliform was detected in all of the pond water samples, four jar and three tube-well water too. E. coli was present in all pond water samples, and also detected in 80% supply and 50% tube-well water also. Shigella spp. was found in two pond water and in one supply water, where tube-well water was free from it. Salmonella spp. was also detected in 30% of pond and 20% of supply water, whereas absent in tube-well water. 50% of pond, 40% of supply and 30% of tube-well water were contaminated with Vibrio spp. The total counts of these

关键词： Physiochemical Parameters Bacterial Load Antibiogram Public Health Nakla Paurosova

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