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All-epiphyseal versus trans-epiphyseal screw fixation for tillaux fractures:Does it matter?

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World Journal of Orthopedics 2022年第2期13卷 131-138页

作者： Brett Heldt Isaiah Roepe raymond guo Elsayed Attia Ifeoma Inneh Vinitha Shenava Indranil Kushare Department of Orthopedic Surgery Baylor College of MedicineHoustonTX 77030United States Department of Orthopedic Surgery Texas Children's HospitalHoustonTX 77030United States

BACKGROUND Tillaux fractures occur primarily in adolescents due to the pattern of physeal closure and are classified as Salter-Harris type III physeal *** management with screw fixation is recommended for more than 2 mm of displacement or more than 1 mm of ***,the efficacy and complications of trans-physeal vs all-physeal screw fixation have not been investigated *** To compare the clinical and functional outcomes of trans-physeal(oblique)and all-epiphyseal(parallel)screw fixation in management of Tillaux fractures among pediatric *** This was an ethics board approved retrospective review of pediatric patients who presented to our tertiary children’s care facility with Tillaux *** included patients who had surgical fixation of a Tillaux fracture over a 10 year *** analysis included demographics,mode of injury,management protocols,and functional *** patients were divided into group 1(oblique fixation)and group 2(parallel fixation).Baseline patient characteristics and functional outcomes were compared between *** tests to evaluate differences included Fisher’s Exact or Chi-squared and independent samples t or Mann Whitney tests for categorical and continuous variables,*** A total of 42 patients(28 females and 14 males)were *** were no significant differences in body mass index,sex,age,or time to surgery between the groups[IK2].Sports injuries accounted for 61.9%of the cases,particularly non-contact(57.1%)and skating(28.6%)*** Tomography(CT)scan was ordered for 28 patients(66.7%),leading to diagnosis confirmation in 17 patients and change in management plan in 11 patients.[GRC3]Groups 1 and 2 consisted of 17 and 25 patients,*** mid to long-term functional outcomes,there were 14 and 10 patients in groups 1 and 2,*** analysis revealed no significant differences in the functional outcomes,pain scores,

关键词： Tillaux fracture Orthopedic surgery Fixation technique Functional outcomes

Chemical composition and in vitro fermentation characteristics of high sugar forage sorghum as an alternative to forage maize for silage making in Tarim Basin, China

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Journal of Integrative Agriculture 2016年第1期15卷 175-182页

作者： ZHANG Su-jiang Abdul Shakoor Chaudhry Diky Ramdani Amerjan Osman guo Xue-feng Grant raymond Edwards Long Cheng Key Laboratory of Tarim Animal Husbandry Science and Technology College of Animal Science Tarim University School of Agriculture Food and Rural Development Newcastle University Faculty of Animal Husbandry University Padjadjaran College of Plant Science and Technology Tarim University Faculty of Agriculture & Life Sciences Lincoln University

The chemical composition, mineral profile and in vitro fermentation characteristics of maize （MZ）, high sugar forage sorghum （HS） and forage sorghum （FS）, and silages made from each forage type were measured. The MZ and MZ silage （MZS） had higher crude protein, starch and ether extract contents than both sorghum forages and sorghum silages. HS had higher ash and water-soluble carbohydrate concentrations than FS and MZ. MZ, MZS, HS and HS silage （HSS） had lower neutral detergent fibre, acid detergent fibre and acid detergent lignin than FS and FS silage （FSS）. FSS had higher dry matter （DM） and pH than MZS and HSS. HSS contained higher concentrations of P and K than FSS and MZS. MZS and HSS had higher in vitro dry matter and organic matter digestibility, CH4 production, total volatile fatty acids, acetate and propionate than FSS. pH was higher for FSS than for HSS, and ammonia was lower for HSS than for MZS and FSS. HSS had higher gas production than MZS and FSS after 2, 4, 6 and 8 h incubation. MZS had higher gas production than HSS and FSS after 26 and 28 h of incubation. The results indicate that HS may substitute for MZ to make good quality silage. However, animal studies are needed to assess the acceptability and feeding values of HSS vs. MZS for ruminant production.

关键词： high sugar forage sorghum maize silage digestibility methane gas production

The proteome of distal nerves: implication in delayed repair and poor functional recovery

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Neural Regeneration Research 2022年第9期17卷 1998-2006页

作者： Song guo raymond M.Moore M.Cristine Charlesworth Kenneth L.Johnson Robert J.Spinner Anthony J.Windebank Huan Wang Department of Neurologic Surgery Mayo ClinicRochesterMNUSA Biomedical Statistics and Informatics Mayo ClinicRochesterMNUSA Proteomics Core Mayo ClinicRochesterMNUSA Department of Neurology Mayo ClinicRochesterMNUSA

Chronic denervation is one of the key factors that affect nerve *** axotomy deteriorates the distal nerve stump,causes protein changes,and renders the microenvironment less permissive for *** of these factors/proteins have been individually *** better delineate the comprehensive protein expression profiles and identify proteins that contribute to or are associated with this detrimental effect,we carried out a proteomic analysis of the distal nerve using an established delayed rat sciatic nerve repair *** rats that received immediate repair after sciatic nerve transection served as control,whereas four rats in the experimental group(chronic denervation)had their sciatic nerve repaired after a 12-week *** the rats were sacrificed after 16 weeks to harvest the distal nerves for extracting ***-five micrograms of protein from each sample were fractionated in SDS-PAGE ***-MS/MS analysis was applied to the *** expression levels of nerves on the surgery side were compared to those on the contralateral *** protein with a P value of less than 0.05 and a fold change of 4 or higher was deemed differentially *** the differentially expressed proteins in both groups were further stratified according to the biological processes.A PubMed search was also conducted to identify the differentially expressed proteins that have been reported to be either beneficial or detrimental to nerve *** Pathway Analysis(IPA)software was used for pathway *** results showed that 709 differentially expressed proteins were identified in the delayed repair group,with a bigger proportion of immune and inflammatory process-related proteins and a smaller proportion of proteins related to axon regeneration and lipid metabolism in comparison to the control group where 478 differentially expressed proteins were *** experimental group also had more beneficial proteins that were d

关键词： chronic axotomy chronic denervation delayed repair distal nerve functional recovery nerve regeneration peripheral nerve prolonged denervation proteome sciatic nerve sciatic nerve transection

The novel male meiosis recombination regulator coordinates the progression of meiosis prophase Ⅰ

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Journal of Genetics and Genomics 2020年第8期47卷 449-464页

作者： Miao Li Haiwei Feng Zexiong Lin Jiahuan Zheng Dongteng Liu Rui guo Junshi Li raymond H.W.Li Ernest H.Y.Ng Michael S.Y.Huen P.Jeremy Wang William S.B.Yeung Kui Liu Shenzhen Key Laboratory of Fertility Regulation Center of Assisted Reproduction and EmbryologyThe University of Hong Kong-Shenzhen HospitalShenzhen518000China Department of Obstetrics and Gynecology Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong999077China Department of Biomedical Sciences University of Pennsylvania School of Veterinary MedicinePhiladelphiaPA19104USA School of Biomedical Sciences Li Ka Shing Faculty of MedicineThe University of Hong KongHong Kong999077China

Meiosis is a specialized cell division for producing haploid gametes in sexually reproducing *** this study,we have independently identified a novel meiosis protein male meiosis recombination regulator(MAMERR)/4930432 K21 Rik and showed that it is indispensable for meiosis prophase I progression in male *** super-resolution structured illumination microscopy,we found that MAMERR functions at the same double-strand breaks as the replication protein A and meiosis-specific with OB domains/spermatogenesis associated 22 *** generated a Mamerr-deficient mouse model by deleting exons 3 e6 and found that most of Mamerrà/àspermatocytes were arrested at pachynema and failed to progress to diplonema,although they exhibited almost intact synapsis and progression to the pachytene stage along with XY body *** mechanistic studies revealed that the recruitment of DMC1/RAD51 and heat shock factor 2 ebinding protein in Mamerrà/àspermatocytes was only mildly impaired with a partial reduction in double-strand break repair,whereas a substantial reduction in ubiquitination on the autosomal axes and on the XY body appeared as a major phenotype in Mamerrà/à*** propose that MAMERR may participate in meiotic prophase I progression by regulating the ubiquitination of key meiotic proteins on autosomes and XY chromosomes,and in the absence of MAMERR,the repressed ubiquitination of key meiotic proteins leads to pachytene arrest and cell death.

关键词： Meiosis 4930432K21Rik Recombination Ubiquitination

支架"摆尾"技术辅助栓塞伴有胚胎型大脑后动脉的后交通动脉宽颈动脉瘤的初步观察

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中华神经外科杂志 2024年第8期40卷 791-796页

作者：韩凯昊郭新宾刘烁陈振权涛范锋徐浩文管生郑州大学第一附属医院神经介入科郑州450002

目的初步观察支架"摆尾"技术辅助弹簧圈栓塞伴有胚胎型大脑后动脉(fPCA)的后交通动脉(PCoA)宽颈动脉瘤的安全性和有效性。方法回顾性分析2018年8月至2023年8月郑州大学第一附属医院神经介入科采用支架"摆尾"技术辅助弹簧圈栓塞伴有fPCA... 详细信息

目的初步观察支架"摆尾"技术辅助弹簧圈栓塞伴有胚胎型大脑后动脉(fPCA)的后交通动脉(PCoA)宽颈动脉瘤的安全性和有效性。方法回顾性分析2018年8月至2023年8月郑州大学第一附属医院神经介入科采用支架"摆尾"技术辅助弹簧圈栓塞伴有fPCA的PCoA宽颈动脉瘤的14例患者的临床资料。观察是否达到技术成功以及操作相关并发症的情况。术后6个月进行电话或门诊随访并择期复查全脑数字减影血管造影(DSA)。神经功能状态以改良Rankin量表评分(mRS)评价,动脉瘤的栓塞效果以raymond分级评价。结果14例患者全部获得技术成功,均未出现操作相关并发症。1例患者术后16 d因呼吸衰竭死亡;另13例患者中,出院时mRS 0分11例,1分1例,2分1例。术后6个月随访时,13例患者的mRS均为0分。11例患者完成DSA随访,随访时间[M(Q_(1),Q_(3))]为7(5,10)个月;结果显示,PCoA均开放良好,未出现支架内狭窄,其中raymond分级Ⅰ级8例,Ⅱ级3例。另2例患者仅复查磁共振血管成像,未见动脉瘤复发。结论初步观察发现,采用支架"摆尾"技术辅助弹簧圈栓塞伴有fPCA的PCoA宽颈动脉瘤的手术并发症较少,且可有效栓塞动脉瘤。

关键词：颅内动脉瘤血管内操作栓塞,治疗性后交通动脉胚胎型大脑后动脉支架"摆尾"技术

单纯放置LVIS支架治疗颅内动脉瘤的初步经验

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中国实用神经疾病杂志 2024年第5期27卷 557-562页

作者：季金璀郭锋赵秀豪李一星于建军潍坊医学院临床医学院山东潍坊261053 临沂市人民医院山东临沂276000

目的探讨单纯使用LVIS支架治疗颅内动脉瘤(IA)的有效性和安全性。方法回顾性收集采取单纯LVIS支架治疗的45例患者临床资料,对IA的特征及影像学随访结果进行分析。结果 45例患者通过单纯放置LVIS支架共治疗48个IA。术后4~24个月接受脑... 详细信息

目的探讨单纯使用LVIS支架治疗颅内动脉瘤(IA)的有效性和安全性。方法回顾性收集采取单纯LVIS支架治疗的45例患者临床资料,对IA的特征及影像学随访结果进行分析。结果 45例患者通过单纯放置LVIS支架共治疗48个IA。术后4~24个月接受脑血管造影复查,中位复查时间7个月。raymond分级Ⅰ级的IA 31个,Ⅱ级4个,Ⅲ级13个,总体治愈率64.58%。单LVIS支架治疗30个IA,治愈率56.67%,双LVIS支架套叠治疗18个IA,治愈率77.78%。所有患者获得出院6个月时的门诊或电话随访,均未发生严重缺血或出血事件。改良Rankin量表评分(mRS)均为0~2分。结论单纯放置LVIS支架治疗IA安全可行,但治愈率低于其辅助弹簧圈栓塞,不宜作为IA的首选治疗方案。对于术中无法填塞弹簧圈或术前不接受血流导向装置以及开颅夹闭术治疗的患者,双LVIS支架治疗可作为备选方案或术中补救措施。

关键词： LVIS支架血管内治疗颅内动脉瘤血流动力学并发症

认知和情感共情与负性情绪:情绪调节的作用机制

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心理学报 2023年第6期55卷 892-904页

作者：郭晓栋郑泓阮盾胡丁鼎王毅王艳郁陈楚侨神经心理学与应用认知神经科学实验室中国科学院心理健康重点实验室(中国科学院心理研究所)北京100101 中国科学院大学心理系北京100049 潍坊医学院心理学院山东潍坊261053

情绪调节在社会情境中对认知和情感共情的影响尚待厘清,这一问题的阐明将有助于理解社会交互中负性情绪的产生和影响机制,为未来的社会认知干预提供理论基础。本文通过问卷调查验证了共情、情绪调节与负性情绪之间的关系,并采用中文版... 详细信息

情绪调节在社会情境中对认知和情感共情的影响尚待厘清,这一问题的阐明将有助于理解社会交互中负性情绪的产生和影响机制,为未来的社会认知干预提供理论基础。本文通过问卷调查验证了共情、情绪调节与负性情绪之间的关系,并采用中文版共情准确性任务探讨认知重评策略使用对共情情绪反应的影响。结果发现:情感共情与日常生活中更多的焦虑和压力有关,而认知共情与更少的抑郁情绪相关,认知重评和表达抑制均在共情与负性情绪之间起保护性调节作用;共情准确性任务中,使用认知重评策略能提高个体对他人消极情绪的共情准确性、降低自身的负性情绪体验;在积极情境下还可以增强个体的积极情绪。结果表明情绪调节,特别是认知重评,在认知和情感共情与负性情绪之间发挥着重要作用。

关键词：认知共情情感共情认知重评表达抑制负性情绪

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雷蒙德·卡弗短篇小说集

CEPC Technical Design Report

1992年

作者：雷蒙德·卡弗(raymond Carver)

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise