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complete Assignment and Benchmarking of an 8-Qubit System

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Journal of Physical Science and Application 2013年第5期3卷 301-311页

作者： Virginia Jaiuregui-Villanueva Guanru Feng Jingfu Zhang raymond Laflamme Institute of Nuclear Sciences National Autonomous University of Mexico Mexico City 04510 Mexico Institute for Quantum computing University of Waterloo 200 University Ave. West Waterloo Ontario N2L 3G1 Canada State Key Laboratory of Low-Dimensional Quantum Physics and Department of Physics Tsinghua University Beijing 100084China

In this paper, the assignment of acomplex 8-spin-half system （7,7-dichloro-6-oxo-2-tio-bicycle [3.2.0] heptane-4-carboxlic acid） using nuclear magnetic resonance （NMR） techniques is presented and the hamiltonian obtained, was used to demonstrate universal control. The system has 313c and 51H,in our work, we carried out traditional 1-D and 2-D experiments and also made use of coherent control together with simulation to get the full hamiltonian of this weakly coupled system. Spin-echo J-resolved 2-D experiments were used to obtain the heteronuclear and homonuclear coupling values; cOSY45 experiments were used to obtain the signs of homonuclear coupling constants. The signs of heteronuclear coupling constants were obtained using the polarization transfer method. All the data obtained in the experiments were used in the simulation of the 1-D spectra and then optimized using the least square fitting method. After obtaining the full hamiltonian of the 8-spin system, we used it in QIP, prepared pseudopure states and implemented 1-qubit and 2-qubit gates on one of its 6-qubit subsystems.

关键词： NMR 1H 13c quantum computing selective 2D-Jresolved seI-cOSY45 13c enriched compound 8-qubit system quantum gates pseudopure states.

cytotoxicity and Selectivity in Skin cancer by Sapc-DOPS Nanovesicles

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Journal of cancer Therapy 2012年第4期3卷 321-326页

作者： Shadi Abu-Baker Zhengtao chu Ashley M. stevens Jie Li Xiaoyang Qi Department of Dermatology University of Miami Miami FL Division of Hematology/Oncology Department of Internal Medicine University of Cincinnati College of Medicine Division of Human Genetics Department of Pediatrics Cincinnati Children’s Hospital Medical Center Cincinnati OH

Squamous cell carcinoma (Scc) and melanoma are malignant human cancers of the skin with an annual mortality that exceeds 10,000 cases every year in the USA alone. In this study, the lysosomal protein saposin c (Sapc) and the phospholipid dioloylphosphatidylserine (DOPS) were assembled into cancer-selective nanovesicles (Sapc-DOPS) and successfully tested using several in vitro and in vivo skin cancer models. Using MTT assay that measures the percentage of cell death, Sapc-DOPS cytotoxic effect on three skin tumor cell lines (squamous cell carcinoma, SK-MEL-28, and MeWo) was compared to two normal nontumorigenic skin cells lines, normal immortalized keratinocyte (NIK) and human fibroblast cell (HFc). We observed that the nanovesicles selectively killed the skin cancer cells by inducing apoptotic cell death whereas untransformed skin cancer cells remained unaffected. Using subcutaneous skin tumor xenografts, animals treated with Sapc-DOPS by subcutaneous injection showed a 79.4% by volume tumor reduced compared to the control after 4 days of treatment. We observed that the nanovesicles killed skin cancer cells by inducing apoptotic cell death compared to the control as revealed by TUNEL staining of xenograft tumor sections.

关键词： Squamous cell carcinoma Melanoma Sapc-DOPS Nanovesicles cytotoxic Effect cancer Selectivity

Morpho-Syntactic Tagging of Text in “Baoule” Language Based on Hidden Markov Models (HMM)

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Journal of Software Engineering and Applications 2016年第10期9卷 516-523页

作者： Hyacinthe Konan Bi Tra Gooré raymond Gbégbé Olivier Asseu Ecole Supérieure Africaine des TIcs (ESATIc) Abidjan C&ocirc te d’Ivoire Institut National Polytechnique Félix Houphouë t Boigny (INP-HB) Yamoussoukro C&ocirc te d’Ivoire

The label text is a very important tool for the automatic processing of language. It is used in several applications such as morphological and syntactic text analysis, index-ing, retrieval, finished networks deterministic (in which all combinations of words that are accepted by the grammar are listed) or by statistical grammars (e.g., an n-gram in which the probabilities of sequences of n words in a specific order are given), etc. In this article, we developed a morphosyntactic labeling system language “Baoule” using hidden Markov models. This will allow us to build a tagged reference corpus and rep-resent major grammatical rules faced “Baoule” language in general. To estimate the parameters of this model, we used a training corpus manually labeled using a set of morpho-syntactic labels. We then proceed to an improvement of the system through the re-estimation procedure parameters of this model.

关键词： corpus the Set of Tags the Morpho-Syntactic Tagging “Baoule” Language Hidden Markov Model

Sinonasal Schwannoma: A case Report and Updated Review of the Literature

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Open Journal of Medical Imaging 2015年第2期5卷 66-70页

作者： Edwin A. Takahashi Nathan c. Hull christopher J. stevens Joseph M. Hoxworth Steven M. Weindling christopher P. Wood Department of Radiology Mayo Clinic Rochester USA Department of Radiology Mayo Clinic Scottsdale USA Department of Radiology Mayo Clinic Jacksonville USA

Sinonasal schwannomas are rare, benign and slow-growing peripheral nerve sheath tumors without age, race, or gender predilection. We present the unusual case of a 59-year-old female who pre-sented with right-sided retro-orbital pressure and rhinorrhea. Radiographic imaging revealed a mass centered in the right superior nasal cavity with extension through the cribriform plate into the right more than the left subfrontal region. Biopsy confirmed the diagnosis of a sinonasal schwannoma, which was resected via nasal endoscopic surgery and ethmoidectomy. These tumors, albeit rare, should be considered in the differential diagnosis for patients presenting with a para-nasal sinus mass to ensure inclusion of this benign lesion and avoid unnecessary aggressive in-tervention.

关键词： Neurilemmoma Paranasal Sinus Sinonasal Tract Schwannoma

脊髓胶状质内生长抑素免疫反应阳性结构与一级传入纤维之间的突触连接

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中国组织化学与细胞化学杂志 1992年第2期1卷 136-142,258页

作者：刘庆莹 raymond H HO 同济医科大学解剖学教研室武汉430030 美国俄亥俄州立大学医学院解剖学教研室 oh43210

本文用单纯免疫电镜及免疫电镜与溃变(后根切断术)相结合的方法,研究了一级传入纤维与脊髓胶状质内生长抑素(SOM)阳性结构之间的突触连结。结果在脊髓胶状质内观察到SOM阳性的胞体、轴突、树突及溃变的轴突,以上结构间形成了几种不同类... 详细信息

本文用单纯免疫电镜及免疫电镜与溃变(后根切断术)相结合的方法,研究了一级传入纤维与脊髓胶状质内生长抑素(SOM)阳性结构之间的突触连结。结果在脊髓胶状质内观察到SOM阳性的胞体、轴突、树突及溃变的轴突,以上结构间形成了几种不同类型的突触连结:(1)Ⅰ型或Ⅱ型突触球的中央成份(cⅠ或cⅡ末梢)是溃变的或是SOM免疫反应阳性的,它们与周围的树突形成轴树突触、轴轴突触或树轴突触,其中有一些周围的树突还是SOM阳性的。(2)某些简单的轴突(不参与构成突触球的轴突)呈暗型溃变,并与SOM阳性的树突形成轴树突触。(3)简单的SOM阳性的致密型轴突与含SOM的树突或核周质形成轴树或轴体突触。(4)简单的SOM阳性的亮型轴突与含SOM的树突形成轴树突触。这些突触关系提示脊髓胶状质内SOM阳性树突和胞体可直接从一级传入纤维或脊髓后角固有神经元接受冲动,其中有一些一级传入纤维和脊髓后角固有神经元也是SOM阳性的。这表明在脊髓固有神经元与一级传入纤维之间及脊髓固有神经元本身都存在着自调节突触。本实验结果为SOM参与感觉信息的调节提供了超微结构证据。

关键词：脊髓胶状质生长抑素突触一级传入免疫细胞化学

Effects of A Galanin-3 Receptor Antagonist on Neurite Outgrowth

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Effects of A Galanin-3 Receptor Antagonist on Neurite Outgro...

Precipitation study of cO2-loaded glycinate solution with the introduction of ethanol as an antisolvent

第十五届国际药理学大会

作者： Kachel c.Alan catapano Jr.raymond Scott Roderick E.M. Blackburn Thomas P. Helicon Therapeutics Inc. Helicon Therapeutics Inc. Helicon Therapeutics Inc. Helicon Therapeutics Inc.

＜正＞ The neuropeptide Galanin mediates its effects through three known G - protein coupled receptor subtypes GalR1,GalR2 and GalR3,and has been implicated in many physiological processes including feeding behavior,pain and depression. Several studies have demonstrated the ability of Galanin to modulate the central 5 - hydroxytryptamine （5 - HT） function. HT - 2157,a selective GalR3 antagonist,has been shown to increase extracellular levels of 5 - HT in various brain regions . 5 - HT - elicitated 5 - HT1A receptor activation increases neurogenesis and promotes neurite outgrowth which may contribute to its antidepressant effects. In this study,the effects of HT- 2157 on enhancing neurite outgrowth were examined and the mechanisms underlying the modulation of neurite outgrowth were explored in both a Pc12 sub - clone and primary mouse neuronal cultures. The results demonstrated that HT2157 significantly enhanced neurite outgrowth of Pc12 cells and primary mouse neurons. In addition,HT- 2157 down regulated a transcription represser of the 5 - HT1A receptor gene,indicating that the enhancement of neurite outgrowth by HT - 2157 is mediated via derepression of 5 - HT1A receptor gene expression.

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Frontiers of chemical Science and Engineering 2020年第3期14卷 415-424页

作者： Siming chen Yue Wu Geoffrey Wstevens Guoping Hu Wenshou Sun Kathryn AMumford college of Environmental Sciences and Engineering Qingdao UniversityQingdao 266071China Peter cook centre for carbon capture and Storage Research(Pcc) Particulate Fluids Processing Centre(PFPC)Department of Chemical EngineeringUniversity of MelbourneParkvilleVictoria 3010Australia

Focused beam reflectance measurement(FBRM)and 13c nuclear magnetic resonance(13c NMR)analysis were used to study the precipitation process of cO2-loaded potassium glycinate(KGLY)solutions at different cO2 loadings,during the addition of ethanol as an antisolvent at a rate of 10 mL·min−*** volume ratio of ethanol added to the KGLY solution(3.0 mol·L−1,340 mL)ranged from 0 to *** solid-liquid-liquid phases were formed during the precipitation *** FBRM results showed that the number of particles formed increased with cO2 loading and ethanol addition for cO2-unsaturated KGLY solutions,whilst for cO2-saturated KGLY solution it first increased then decreased to a stable value with ethanol addition.13c NMR spectroscopic analysis showed that the crystals precipitated from the cO2-unsaturated KGLY solutions consisted of glycine only,and the quantity crystallised increased with cO2 loading and ethanol ***,a complex mixture containing glycine,carbamate and potassium bicarbonate was precipitated from cO2-saturated KGLY solution with the maximum precipitation percentages of 94.3%,31.4%and 89.6%,respectively,at the ethanol volume fractions of 1.6,2.5 and 2.3.

关键词： crystallization precipitation glycinate FBRM 13c NMR

EFFEcT OF POTASSIUM INFUSION ON THORAcIc DUcT LYMPH FLOW IN LAMBS

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山东大学学报(医学版) 1989年第3期 77-83页

作者：董全胜,raymond D.Gilbert,Gordon G.Power Department of Pathophysiology Shandong Medical University Jinan P.R.c. Division of Perinatal Biology Department of Physiology Loma Linda University School of Medicine Loma Linda california 92350 U.S.A. Division of Perinatal Biology Department of Physiology Loma Linda University School of Medicine Loma Linda california 92350 U.S.A.

To assess distinctive characteristic of potassium on tho-racic duct lymph flow,response to infusion of isotonic Kc1 solution wascompared to that of isotonic Nacl solution in seven anesthetized *** flow rate,hematocrit,plasma and lymph protein andpotassium concentration,plasma and lymph osmolalities were *** lymph volume over 30 min infusion period was calculated fromthe area under lymph flow *** findings were:(1)Thoracicduct lymph flow rate increased more and came up earlier during Kcl in-fusion than during Nacl *** lymph volume response to Kclinfusion was markedly higher than that to Nacl infusion:(2)Relativeblood volume increase during Nacl infusion was significantly more thanthat during Kcl infusion and(3)plasma protein concentration decreasedmarkedly during Nacl but not during Kcl infusion,These data suggestthat elevated plasma potassium may stimulate thoracic duct lymph flowby increasing capillary filtration rate.

关键词： Potassium Thoracic duct lymph flow Lymphatic contraction capillary filtration rate

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亚利桑那州的巨型干裂缝

水文地质工程地质技术方法动态 2006年第6期 33-35页

作者： raymond c．Harris 于小芳（翻译）葛秀珍（校对）亚利桑那地质调查局

自1998年以来，亚利桑那州地质调查局就收到许多州周边大范围多个分散地点出现新裂缝的有关报告。此前90年代中期，报告的大部分裂缝均是人们所熟悉的类型，即开采地下水造成地面塌陷引发的地裂缝。然而，这些新裂缝大部分被证明具有不... 详细信息

自1998年以来，亚利桑那州地质调查局就收到许多州周边大范围多个分散地点出现新裂缝的有关报告。此前90年代中期，报告的大部分裂缝均是人们所熟悉的类型，即开采地下水造成地面塌陷引发的地裂缝。然而，这些新裂缝大部分被证明具有不同的诱因——富含粘土的土壤或沉积物的干燥或被烘干。通过绘制这些被报道裂缝的地图及观察其航空照片，结果显示，这些“巨型干裂缝（GDc）”要比预先想象的普遍的多，并且比由开采地下水引起的地裂缝广泛的多。通过绘制亚利桑那州这些巨型干裂缝的地图，最近完成的一项研究证明了勘测的结果。这篇文章概述了那篇报道。

关键词：亚利桑那州地裂缝巨型开采地下水地质调查局地面塌陷航空照片沉积物