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Breast cancer in India:Present scenario and the challenges ahead

World Journal of Clinical Oncology 2022年第3期13卷 209-218页

作者： ravi mehrotra Kavita Yadav Department of Health Research Ministry of Health and Family WelfareIndia Cancer Research ConsortiumNew Delhi 110001India CHIP Foundation Noida 201301India Centre of Social Medicine&Community Health Jawahar Lal Nehru UniversityNew Delhi 110067India

Breast cancer is the commonest malignancy among women *** being fourth in the list of most common cancers in India during the 1990s,it has now become the *** this review,we examine the available literature to understand the factors that contributed to the high burden of breast cancer in the *** also provide the landscape of changes in the field of early diagnosis and the treatment modalities as well as the limitations of the Indian healthcare delivery systems(e.g.,delayed diagnosis,human resources and funding for treatment).This review also sheds light on the newer interventions and the future of breast cancer management keeping in mind the coronavirus disease 2019 imposed limitations.

关键词： Breast cancer Challenges Prospects India Treatment

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Carcinogenic Helicobacter pylori in gastric pre-cancer and cancer lesions: Association with tobacco-chewing

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World Journal of Gastroenterology 2014年第22期20卷 6860-6868页

作者： Arvind Pandey Satyendra Chandra Tripathi Sutapa Mahata Kanchan Vishnoi Shirish Shukla Sri Prakash Misra Vatsala Misra Suresh Hedau ravi mehrotra Manisha DwivediZ Alok C Bharti Divisionof Molecular Oncology Institute of Cytology and Preventive Oncology (ICMR)Noida 201301India Center for Biotechnology University of AllahabadAllahabad 211002India Clinical Cancer Prevention-Research UT MD Anderson Cancer CenterHoustonTX 77030United States Department of Gastroenterology MLN Medical CollegeAllahabad 211002India Department of Pathology MLN Medical CollegeAllahabad 211002India

AIM: To investigate the low gastric cancer incidence rate relative to the highly prevalent Helicobacter pylori (H. pylori) infection; data relevant to H. pylori infection during gastric carcinogenesis in Indian patien... 详细信息

关键词： UreC CagA Dysplasia Intestinal metaplasia Gastric adenocarcinoma Tobacco chewing

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Association of metabolic NCD risk factors with oral, breast and cervical precancers and cancers in India

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Family Medicine and Community Health 2019年第4期7卷 37-45页

作者： Ashwini Kedar Roopa Hariprasad Vipin Kumar Kavitha Dhanasekaran ravi mehrotra Department of Clinical Oncology National Institute of Cancer Prevention and ResearchNoidaIndia

Objective To find an association between metabolic non-communicable disease(NCD)risk factors(high blood pressure(BP),high random blood sugar(RBS)and overweight/obesity)and oral,breast,cervical cancers/precancerous or potentially malignant *** This is an observational study using convenience *** participants were screened through opportunistic or population-based *** The study was conducted at a health promotion clinic(HPC)located in Northern India under the Indian Council of Medical *** is a screening clinic where screening is done for hypertension(HT),diabetes mellitus(DM),obesity,and oral,breast and cervical *** study was conducted between December 2016 and January *** The number of participants screened was 8352(6712 women and 1640 men).All consenting men and women above 18 years were *** participants were screened for oral cancer,DM,HT and *** women were also screened for breast and cervical *** screening was done for non-pregnant women 21 years and above with history of sexual *** Oral potentially malignant disease(OPMD)was the most prevalent,followed by breast cancer,oral cancer,cervical cancer and cervical *** RBS had a strong association with oral cancer(OR=2.29,95%CI 1.09 to 4.82,p=0.03)and breast cancer(OR=1.95,95%CI 1.01 to 3.76,p=0.05).High BP had a strong association with breast cancer(OR=2.50,95%CI 1.43 to 4.35,p<0.0001).An inverse association was noted between oral cancer and overweight/obesity(OR=0.20,95%CI 0.08 to 0.48,p<0.0001).Current tobacco use was strongly associated with oral cancer(OR=6.51,95%CI 3.63 to 11.67,p<0.0001)and OPMD(OR=9.82,95%CI 8.13 to 11.86,p<0.0001).No association was elicited between the metabolic NCD risk factors and cervical cancer/*** The study reaffirms that NCD metabolic risk factors determine oral and breast *** NCD risk factors,current tobacco use was a strong determinant

关键词： cervical breast cancers

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