检索结果-南通市图书馆

新营销 2014年第4期16卷 15-15页

作者： Jens Martin Skibsted rasmus bech hansen

当今消费者掌握的信息越来越多，对于品牌而言，怎样才算是做好传播工作。该文提出，对于品牌而言，必须遵循一个最清晰的逻辑：品牌最重要的角色，就是让消费者更容易做购买决策，并强调让品牌变得更具聚焦性的重要性…

关键词：品牌建设工具传统传播工作购买决策消费者聚焦性

Is there consensus regarding surgical treatment of bone sarcomas?

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World Journal of Orthopedics 2018年第9期9卷 173-179页

作者： Thomas Baad-hansen Sarah Stammose Freund Bodil Hammer bech Johnny Keller Department of Orthopaedic Oncology Aarhus University Hospital Department of Public Health Aarhus University

AIM To perform an Internet based survey on the surgical management of bone sarcomas in the lower extremity amongst sarcoma surgeons. METHODS All orthopedic surgical members of the Scandinavian Sarcoma Group were invited to participate in an online questionnaire. The questionnaire consisted of a clinical case involving resection of a malignant bone tumor. Several questions were asked, subdivided into categories. Among these, surgical/technical considerations, e.g., choice of implant; choice of antibiotics, dosage, and duration of treatment, choice of antithrombotic drug, initial start-up, dosage, and duration were *** In terms of choice of implant fixation, the majority of surgeons preferred an uncemented prosthesis in younger patients until the age of 50. All participants administer intravenous prophylactic antibiotics for endoprosthetic reconstructive surgery. First choice of antibiotics was cephalosporin. Less common used was glycopeptide, penicillin, or a combination. Duration of prophylactic antibiotics ranged from less than one day to more than four days. All participants used low molecular weight heparins as antithrombotic prophylaxis and 55% of the participants answered that initial treatment was started preoperatively, 3% perioperatively and 42% postoperatively. Duration of the antithrombotic treatment ranged from five days to more than twenty-eight *** The use of resection prosthesis in the treatment of bone sarcomas is a well-established procedure. However, therse is a significant discrepancy in the surgical treatment algorithm between the sarcoma centers. Still the treatment is mainly based on best clinical practice,due to the lack of evidence-based medicine in the surgical management of bone sarcomas.

关键词： Sarcoma Reconstruction Megaprosthesis Antibiotics Antithrombotic prophylaxis

Highly Increased Levels of Inter-α-inhibitor Heavy Chain 4(ITIH4)in Autoimmune Cholestatic Liver Diseases

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Journal of Clinical and Translational Hepatology 2022年第5期10卷 796-802页

作者： Tea Lund Laursen Lars Bossen rasmus Pihl Anne Troldborg Thomas Damgaard Sandahl Annette Gudmann hansen Trine Folserass Mette Vesterhus Henning Grønbæk Steffen Thiel Department of Hepatology and Gastroenterology Aarhus University HospitalAarhusDenmark Department of Biomedi-cine Aarhus UniversityAarhusDenmark Department of Rheumatology Aarhus University HospitalAarhusDenmark Department of Clinical Medicine Aarhus UniversityAarhusDenmark Norwegian PSC Research Center Department of Transplantation MedicineDivision of SurgeryInflammatory Diseases and TransplantationOslo University Hospital Rik-shospitaletOsloNorway Haraldsplass Deaconess Hospital BergenNorway Department of Clinical Science University of BergenBergenNorway

Background and Aims:There is an unmet need for new bi-omarkers to improve diagnostics and prognostics in primary biliary cholangitis(PBC)and primary sclerosing cholangitis(PSC).Inter-α-inhibitor heavy chain 4(ITIH4)is an abun-dant,liver-produced protein,and its synthesis may be al-tered in liver *** investigated whether ITIH4 plas-ma concentrations were affected in PBC and PSC ***:We developed an immunoassay specific for ITIH4 and determined ITIH4 plasma concentrations in 66 PBC,126 PSC,92 autoimmune hepatitis(AIH),67 chronic hepatitis C(CHC),33 alcoholic hepatitis(AH)patients and 138 healthy controls(HCs).Hepatic ITIH4 expression was investigated by immunohistochemistry in ***:The mean plas-ma concentration of ITIH4 was almost doubled in PBC[409μg/mL(95%CI:388-431)]and 35%higher in PSC[308μg/mL,(95%CI:296-319)]compared with HCs[226μg/mL(95%CI:221-231);p<0.001].In PBC patients,ITIH4 correlated with IgM(rho=0.49,p<0.001).Responders to ursodeoxycholic acid treatment(UDCA)had lower levels of ITIH4 than incomplete responders[395μg/mL(95%CI:364-425)]vs.460μg/mL(95%CI:421-498);p=0.02].Four weeks of UDCA treatment had no effect(p=0.19).In-creased ITIH4 immunohistochemical staining was seen in a liver biopsy from a PBC ***4 levels in AIH[224μg/mL(95%CI:208-241)]and HCs were similar(p=0.8).ITIH4 levels were lower in AH[199μg/mL(95%CI:175-223)]and CHC[202μg/mL(192-212)]patients than in HCs(p<0.05).Conclusions:The plasma concentration of ITIH4 was highly elevated in patients with PBC and PSC,suggesting that ITIH4 should be further investigated as a biomarker in cholestatic liver disease.

关键词： Primary biliary cholangitis Primary sclerosing cholangitis Autoim-mune hepatitis Ursodeoxycholic acid treatment Alcoholic hepatitis Chronic viral hepatitis

Preservation of Raw Camel Milk by Lactoperoxidase System Using Hydrogen Peroxide Producing Lactic Acid Bacteria

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Open Journal of Animal Sciences 2020年第3期10卷 387-401页

作者： Dakalo Dashe Egon bech hansen Mohammed Yusuf Kurtu Tesfemariam Berhe Mitiku Eshetu Yonas Hailu Amsalu Waktola Adane Shegaw School of Animal and Range Sciences Haramaya University Dire Dawa Ethiopia Division for Diet Disease Prevention and Toxicology National Food Institute Technical University of Denmark Kgs. Lyngby Den-mark

This study was conducted to investigate the effect of lactic acid bacteria (LAB) activated lactoperoxidase system (LPs) on keeping quality of raw camel milk at room temperature. Camel milk samples were collected from Errer valley, Babile district of eastern Ethiopia. The level of hydrogen peroxide (H2O2) for activation of LPs was optimized using different levels of exogenous H2O2. Strains of LAB (Lactococcus lactis 22333, Weissella confusa 22308, W. confusa 22282, W. confusa 22296, S. Infatarius 22279 and S. lutetiensis 22319) with H2O2 producing properties were evaluated, and W. confusa 22282 was selected as the best strain to produce H2O2. Storage stability of the milk samples was evaluated through the acidification curves, titratable acidity (TA), total bacterial count (TBC) and coliform counts (CC) at storage times of 0, 6, 12, 18, 24 and 48 hours. The LP activity and the inhibitory effect of activated LPs were evaluated by growing E. coli in pasteurized and boiled camel milk samples as contaminating agent. Results indicated that the W. confusa 22282 activated LPs generally showed significantly (P < 0.05) slower rates of acidification, lactic acid production and lower TB

关键词： Camel Milk Lactoperoxidase System Lactic Acid Bacteria Preservation

Fitness components of Drosophila melanogaster developed on a standard laboratory diet or a typical natural food source

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Insect Science 2016年第5期23卷 771-779页

作者： Torsten Nygaard Kristensen Astrid Kallestrup Henningsen Christian Aastrup Mads bech-hansen Lise B. Hoberg Bjerre Benjamin Carlsen Marie Hagstrup Sofie Graarup Jensen Pernille Karlsen Line Kristensen Cecillie Lundsgaard Tine MФller Lise D. Nielsen Camilla Starcke Christine Riisager SФrensen Mads Fristrup Schou Department of Chemistry and Bioscience Section of Biology and Environmental Science Aalborg University Aalborg East DK-9220 Denmark Department of Bioscience Aarhus University Aarhus C DK-8000 Denmark

Drosophila melanogaster is often used as a model organism in evolution- ary biology and ecophysiology to study evolutionary processes and their physiological mechanisms. Diets used to feed Drosophila cultures differ between laboratories and are often nutritious and distinct from food sources in the natural habitat, Here we rear D. melanogaster on a standard diet used in our laboratory and a field diet composed of decomposing apples collected in the field. Flies developed on these two diet compositions are tested for heat, cold, desiccation, and starvation resistance as well as developmental time, dry body mass and fat percentage. The nutritional compositions of the standard and field diets were analyzed, and discussed in relation to the phenotypic observations. Results showed marked differences in phenotype of flies from the two types of diets. Flies reared on the field diet are more starvation resistant and they are smaller, leaner, and have lower heat resistance compared to flies reared on the standard diet. Sex specific effects of diet type are observed for several of the investigated traits and the strong sexual dimorphism usually observed in desiccation resistance in D. melanogaster disappeared when rearing the flies on the field diet. Based on our results we conclude that care should be taken in extrapolating results from one type of diet to another and especially from laboratory to field diets.

关键词： diet field fitness life-history traits nutrition stress resistance

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SUPERKILEN

建筑技艺 2012年第2期18卷 44-49页

作者： Ondrej Tichy Jonas Lehmann Rune hansen Jan Borgstrφm Lacin Karaoz Jonas Barre Nicklas Antoni Rasch Gabrielle Nadeau Jennifer Dahm Petersen Richard Howis Andreas Castberg Armen Menendian Jens Majdal Kaarsholm Jan Magasanik Toni Offenberger Katia Steckemetz Cristian Bohne Karoline Liedtke Jakob Fenger rasmus Nielsen Bjφrnstjerne Christiansen 张岩 Superflex BIG Topotek1

正Superkilen是BIG、Topotek1和SUPERFLEX之间创造性合作的成果,从早期的概念设计到施工设计阶段的密切配合,成就了建筑、景观和艺术的完美融合。该项目是将半英里长的城市空间嵌入到丹麦种族最多样化和最具社会挑战性的一个街区中去。... 详细信息

正Superkilen是BIG、Topotek1和SUPERFLEX之间创造性合作的成果,从早期的概念设计到施工设计阶段的密切配合,成就了建筑、景观和艺术的完美融合。该项目是将半英里长的城市空间嵌入到丹麦种族最多样化和最具社会挑战性的一个街区中去。设计师们有一个总体的想法。

关键词：设计师概念设计密切配合城市空间广场设计阶段景观创造性公园多样化

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丹麦国家海事博物馆

城市环境设计 2019年第2期118卷 142-159页

作者： John Pries Jensen Henrik Kania Ariel Joy Norback Wallner rasmus Pedersen Annette Jensen Dennis rasmussen Jan Magasanik Jeppe Ecklon Karsten Hammer hansen rasmus Rodam Rune hansen Alina Tamosiunaite Alysen Hiller Ana Merino Armen Menendian Andy Yu Andreas Johansen Baptiste Blot Christian Alvarez Christin Svensson Claudia Hertrich Claudio Moretti Cory Mattheis Eskild Nordbud Felicia Guldberg Finn N?rkj?r Gül Ertekin Jan Borgstr?m James Schrader Johan Cool Jonas M?nster Kirstine Ragnhild Malte Kloe Michael Andersen Michal Kristof Marc Jay Maria Mavriku Masatoshi Oka Oana Simionescu Pablo Labra Peter Rieff Qianyi Lim Sara Sosio Sebastian Latz Tina Lund H?jgaard Tina Troster Todd Bennet Xi Chen Xing Xiong Xu Li Zoltan Kalaszi Iwan Baan rasmus Hjortshoj Luca Santiago Mora Dragoer Luftfoto Jens Lindhe Lorenzon Boddi Thiks Wolzak 陈子钰

丹麦海事博物馆位于独特的历史和空间环境中:在丹麦最重要和最著名的建筑之一克伦堡城堡和文化庭院——一个新的、雄心勃勃的文化中心之间。BIG建议将博物馆放在地下,就在船坞的墙壁外侧,以便将船坞保留为开放的户外展示空间,保存其强... 详细信息

丹麦海事博物馆位于独特的历史和空间环境中:在丹麦最重要和最著名的建筑之一克伦堡城堡和文化庭院——一个新的、雄心勃勃的文化中心之间。BIG建议将博物馆放在地下,就在船坞的墙壁外侧,以便将船坞保留为开放的户外展示空间,保存其强有力的结构作为海事博物馆中心。将博物馆这样设置,使它在成为与克伦堡城堡和邻近的文化庭院相联系的文化环境的一部分的同时,彰显自身,成为一个独立

关键词：海事博物馆铝覆层 Section 重钢结构

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深圳能源大厦

建筑实践 2019年第6期 26-33页

作者： Bjarke Ingels Andreas Klok Pedersen Martin Voelkle He Song Andre Schmidt Alessio Zenaro Alina Tamosiunaite Alysen Hiller Ana Merino Andreas Geisler Johansen Annette Jensen Armor Rivas Balaj IIulian Brian Yang Baptiste Blot Buster Christiansen Cecilia Ho Christian Alvarez Christin Svensson Claudia Hertrich Claudio Moretti Cory Mattheis Dave Brown Dennis rasmussen Doug Stechschulte Eskild Nordbud Felicia Guldberg Fred Zhou Gaetan Brunet Gül Ertekin Henrik Kania Iris Van der Heide James Schrader Jan Magasanik Jan Borgstr?m Jeppe Ecklon Jelena Vucic Jo?o Albuquerque Jonas M?nster Karsten hansen Malte Kloe Mikkel Marcker Stubgaard Michael Andersen Michal Kristof Min Ter Lim Oana Simionescu Nicklas A. Rasch Philip Sima rasmus Pedersen Rune hansen Rui Huang Sofia Gaspar Stanley Lung Sun Ming Lee Takuya Hosokai Todd Bennett Xi Chen Xing Xiong Xiao Lu Xu Li Yijie Dan Zoltan Kalaszi BIG

深圳能源公司办公楼项目总建筑面积为96000m2,旨在让人在深圳的文化、政治和商业中心感到亲切的同时,在城市主轴线上建造一座可持续的新公共地标。本项目的体量和高度由中心区城市总体规划决定。主体建筑由两座塔楼组成,北楼高220m,南楼... 详细信息

深圳能源公司办公楼项目总建筑面积为96000m2,旨在让人在深圳的文化、政治和商业中心感到亲切的同时,在城市主轴线上建造一座可持续的新公共地标。本项目的体量和高度由中心区城市总体规划决定。主体建筑由两座塔楼组成,北楼高220m,南楼高120m,两座塔楼与邻近建筑的塔楼一起在深圳的中心形成一个连续的弧形天际线。在建筑底部,两座塔楼通过一个34m长,包括大厅、会议中心、自助餐厅和展览空间功

关键词： Michael 建筑面积建筑实践

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老海勒鲁普高中体育馆

城市环境设计 2019年第2期118卷 114-127页

作者： Ana Merino Anders Hjortn?s Christian Alvarez Dennis rasmussen Gül Ertekin Henrick Poulsen Hjalti Gestsson Jan Magasanik Jakob Lange Jacob Thomsen Jeppe Ecklon Ji-young Yoon Michael Sch?nemann Narisara Schr?der Riccardo Mariano Rune hansen Snorre Nash Thomas Juul-Jensen Vincent He Xu Li Agnete Jukneviciute Ambra Chiesa Brigitta Gulyás Dennis rasmussen Enea Michelesio Greta Krenciute H?gni Laksáfoss Isabella Eriksson Jan Magasanik Mikkel Marcker Stubgaard Jeppe Ecklon Kamilla Heskje Michael Sch?nemann Narisara Schr?der Thomas Juul-Jensen Brigitta Gulyás Enea Michelesio Jakob Lange Mikkel Marcker Stubgaard Narisara Schr?der Tobias Hjortdal Iwan Baan Peter Moldow rasmus Hjortshoj Jens Lindhe 朱翰林

位于哥本哈根北部的老海勒鲁普高中,内部拥有1100m2的多功能大厅和最新的两层建筑,为现有学生提供了广阔的社交和创意展示空间,同时提升学校的容量,以应对持续增长的人口需求。原本校园旁边的一栋建筑里,体育设施匮乏而无法满足需求;老... 详细信息

位于哥本哈根北部的老海勒鲁普高中,内部拥有1100m2的多功能大厅和最新的两层建筑,为现有学生提供了广阔的社交和创意展示空间,同时提升学校的容量,以应对持续增长的人口需求。原本校园旁边的一栋建筑里,体育设施匮乏而无法满足需求;老海勒鲁普高中也缺少大型多功能空间,用以举办体育活动、毕业典礼和社交聚会。为此,BIG为学生

关键词：体育馆

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法罗群岛教育中心

城市环境设计 2019年第2期118卷 84-99页

作者： H?gni Laksáfoss Alberte Danvig Alejandro Mata Gonzales Alessio Valmori Alexandre Carpentier Annette Birthe Jensen Armen Menendian Athena Morella Baptiste Blot Boris Peianov Camille Crepin Claudio Moretti Dag Pr?stegaard Daniel Pihl David Zahle Edouard Boisse Elisha Nathoo Enea Michelesio Eskild Nordbud Ewelina Moszczynska Frederik Lyng Goda Luksaite Henrik Kania H?gni Laksáfoss Jakob Lange Jakob Teglg?rd hansen Jan Besikov Jan Kudlicka Jan Magasanik Jeppe Ecklon Jesper Boye Andersen Ji-Young Yoon Johan Cool Kari-Ann Petersen Kim Christensen Kristoffer Negendahl Long Zuo Martin Cajade Michael Sch?nemann Jensen Mikkel Marcker Stubgaard Niklas Rausch Norbert Nadudvari Oana Simionescu Richard Howis Sabine Kokina Simonas Petrakas Sofia Sofianou Takumi Iwasawam Tobias Hjortdal Tommy Bj?rnstrup Victor Bejenaru Xiao Xuan Lu rasmus Hjortshoj 曲鸿

格拉西尔坐落于法罗群岛起伏的峡湾上,坐拥大海和青翠的海湾景观,首都托尔斯港的景色一览无余。格拉西尔旨在把法罗群岛体育学校、托尔斯港技术学院和法罗群岛商学院合并在一起,提高整体效率,惠及1 750名师生和员工。通过创新孵化器的形... 详细信息

格拉西尔坐落于法罗群岛起伏的峡湾上,坐拥大海和青翠的海湾景观,首都托尔斯港的景色一览无余。格拉西尔旨在把法罗群岛体育学校、托尔斯港技术学院和法罗群岛商学院合并在一起,提高整体效率,惠及1 750名师生和员工。通过创新孵化器的形式,不同于传统学校,格拉西尔既保留了三所学校的自主权,又为学校之间合作学习的蓬勃发展创造了理想条件。根据学生和教师的内部需求,

关键词：法罗群岛教师准备托尔斯港格拉西平面图卫生间教育中心