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Contemporary minimal invasive surgical management of stones in children

Asian Journal of Urology 2023年第3期10卷 239-245页

作者： rasim guzel Umit Yildirim Kemal Sarica Department of Urology Medistate Kavacık HospitalIstanbulTurkey Department of Urology Medical SchoolKafkas UniversityKarsTurkey Department of Urology Medical SchoolBiruni UniversityIstanbulTurkey

Objective:Pediatric urolithiasis has been more common over the past 20 years,and urologists have unique challenges in managing it surgically because this particular demographic is recognized as one of the high-risk categories for stone *** this reality,care focuses on maintaining renal function,achieving total stone-free status,and most importantly avoiding stone *** this presented article,we aimed to make a comprehensive review of the current minimally invasive treatment of pediatric kidney stone ***:We evaluated the results of 74 studies following a comprehensive PubMed search till February *** article was written by making use of current urology ***:Considering the reported occurrence of metabolic issues in up to 50%of cases in addition to the anatomic anomalies(about 30%of cases),the treatment of pediatric urolithiasis necessitates a full metabolic and urological examination on an individual *** management of metabolic imbalances and obstructive diseases is *** addition to encouraging proper fluid consumption,it is advisable to improve urine volume and consider using medical therapeutics to raise urinary citrate *** location,content,and size of the stone(s),the morphology of the collecting system,the presence of urinary tract infection,as well as the presence of any obstruction,should all be taken into consideration while deciding on the best surgical ***:All modern endourological methods are now used in the safe and efficient care of pediatric urolithiasis as a consequence of the obvious advancements in instrument technology and expanding expertise derived from adult *** minimally invasive procedures,such as ureterorenoscopy and percutaneous nephrolithotomy,require more expertise and can be successfully applied with careful management for an excellent stone-free rate with minimal *** these procedures,shock wave lithotripsy is still the first ch

关键词： Urinary calculi Shock wave lithotripsy Percutaneous nephrolithotomy Ureteroscopy

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Spatially distributed cytokinins:Metabolism,signaling,and transport

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Plant Communications 2024年第7期5卷 52-67页

作者： Jiangzhe Zhao Jingqi Wang Jie Liu Penghong Zhang guzel Kudoyarova Chang-Jun Liu Kewei Zhang Zhejiang Provincial Key Laboratory of Biotechnology on Specialty Economic Plants College of Life SciencesZhejiang Normal UniversityJinhuaZhejiang 321004P.R.China Ufa Institute of Biology Ufa Federal Research CenterRASProspekt Oktyabrya 69Ufa 450054Russia Biology Department Brookhaven National LaboratoryUptonNY 11973USA

Cytokinins are mobile phytohormones that regulate plant growth,development,and environmental *** major cytokinin species include isopentenyl adenine(iP),trans-zeatin(tZ),cis-zeatin(cZ),and dihydrozeatin(DZ).The spatial distributions of different cytokinin species in different organelles,cells,tissues,and organs are primarily shaped by biosynthesis via isopentenyltransferases(IPT),cytochrome P450 monooxygenase,and 50-ribonucleotide phosphohydrolase and by conjugation or catabolism via glycosyltransferase or cytokinin oxidase/*** bind to histidine receptor kinases in the endoplasmic reticulum or plasma membrane and relay signals to response regulators in the nucleus via shuttle proteins known as histidine phosphotransfer *** movements of cytokinins from sites of biosynthesis to sites of signal perception usually require long-distance,intercellular,and intracellular *** the past decade,ATP-binding cassette(ABC)transporters,purine permeases(PUP),AZA-GUANINE RESISTANT(AZG)transporters,equilibrative nucleoside transporters(ENT),and Sugars Will Eventually Be Exported transporters(SWEET)have been characterized as involved in cytokinin transport *** review begins by introducing the spatial distributions of various cytokinins and the subcellular localizations of the proteins involved in their metabolism and *** focus on an inventory of the characterized transporters involved in cytokinin compartmentalization,including long-distance,intercellular,and intracellular transport,and the regulation of the spatial distributions of cytokinins by environmental *** directions for cytokinin research are also discussed.

关键词： cytokinin biosynthesis transporter signal transduction environmental changes

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Employment and development levels in rural areas of the Russian Federation

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Regional Sustainability 2024年第3期5卷 124-134页

作者： guzel SALIMOVA Gulnara NIGMATULLINA Gamir HABIROV Alisa ABLEEVA Rasul GUSMANOV Department of Finance Analysis and Accounting TechnologiesBashkir State Agrarian UniversityUfa450001the Russian Federation Department of Economics and Management Bashkir State Agrarian UniversityUfa450001the Russian Federation

The development of agro-industrial complex is important for ensuring national food security and national *** development of rural areas is subject to the development of agriculture and local infrastructure,as well as the availability of various *** study selected 15 indicators in 2021 to analyze the employment and development levels in rural areas of 71 regions of the Russian Federation using the analytical grouping *** results indicated that 20 regions(Group 1)had the highest percentage of rural population(33.10%).The percentage of population engaged in agriculture had the highest value(12.40%)in 31 regions(Group 2).Moreover,20 regions(Group 3)had the highest investments in fixed assets at the expense of municipal budget(11.80 USD/person).Increasing the investments in fixed assets carried out from the budget of the municipality can improve the employment level in rural ***,we used cluster analysis to divide 14 regions of the Volga Federal District in the Russian Federation into 3 *** 1 covered Kirov Region and Republic of Mari El;Cluster 2 included Ulyanovsk Region,Saratov Region,Nizhny Novgorod Region,Perm Territory,Orenburg Region,Chuvash Region,and Republic of Mordovia;and Cluster 3 contained Republic of Tatarstan,Samara Region,Udmurtian Republic,Penza Region,and Republic of *** indicated that the 2 regions of Cluster 1 need to increase the availability of resources and natural gas and improve the investment attractiveness of rural *** 7 regions of Cluster 2 needed to develop infrastructure,public services,and agricultural *** found the highest employment level in rural areas,the largest investments in fixed assets at the expense of municipal budget,the largest residential building area per 10,000 persons,and the largest individual residential building area in the 5 regions of Cluster *** study makes it possible to draw up a comprehensive regional development program and proves the

关键词： Rural areas Employment level Labor productivity Investments in fixed assets Sustainable Development Goal(SDG) Russian Federation

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GrSbner-Shirshov Bases of Some Semigroup Constructions

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Algebra Colloquium 2015年第1期22卷 35-46页

作者： Eylem guzel Karpuz Karamanoglu Mehmetbey University Kamil Ozdag Science Faculty Department of Mathematics Yunus Emre Campus 70100 Karaman Thrkey

In this paper, we obtain （non-commutative） GrSbner-Shirshov bases for rect- angular bands, small extensions of semigroups and Bruck-Reilly extensions of monoids in terms of the general product.

关键词： GrSbner-Shirshov basis semigroup Bruck-Reilly extension

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Simulation of Turbulent Flows Using a Finite-Volume Based Lattice Boltzmann Flow Solver

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Communications in Computational Physics 2015年第1期17卷 213-232页

作者： Goktan guzel Ilteris Koc ASELSAN Inc MGEO DivisionEtlik 06011AnkaraTURKEY

In this study,the Lattice Boltzmann Method(LBM)is implemented through a finite-volume approach to perform 2-D,incompressible,and turbulent fluid flow analyses on structured *** though the approach followed in this study necessitates more computational effort compared to the standard LBM(the so called stream and collide scheme),using the finite-volume method,the known limitations of the stream and collide scheme on lattice to be uniform and Courant-Friedrichs-Lewy(CFL)number to be one are ***,the curved boundaries in the computational domain are handled more accurately with less *** improvements pave the way for the possibility of solving fluid flow problems with the LBM using coarser grids that are refined only where it is necessary and the boundary layers might be resolved better.

关键词： Lattice Boltzmann Method finite-volume approach turbulent flows

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Neuronal cell death and regeneration in diseases associated with advanced glycation end-products accumulation

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Neural Regeneration Research 2014年第7期9卷 701-702页

作者： guzel Bikbova Toshiyuki Oshitari Shuichi Yamamoto Department of Ophthalmology and Visual Science Chiba University Graduate School of Medicine

Recent studies have shown that the glycation-associated damage is not limited to patients with diabetes. Because of their association with ox- idative stress, advanced glycation end-products （AGEs） have also been implicated in many neurodegenerative diseases, such as Huntington disease, amyotrophic lateral sclerosis, and Alzheimer disease （Yan et al., 1996; Ma and Nicholson, 2004）. As in other age-dependent neurode- generative diseases of the brain, oxidative stress-associated age-depen- dent pathogenic processes are not unexpected in glaucoma because this disease is also more common in the elderly （Tezel et al. 2007）.

关键词： NEUROTROPHIC FACTORS PROTEIN EXPRESSION APOPTOSIS DEGENERATION INHIBITORS RECEPTOR TRKB

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Evaluation of the efficiency of fixed assets of economic sectors based onindex analysis

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Journal of Management Analytics 2022年第3期9卷 369-382页

作者： Alisa Ableeva guzel Salimova Tatiana Lubova Almira Farrahetdinova Raisa Siraeva Department of Accounting Statistics and Information Systems in EconomyFederal State Budgetary Educational Establishment of Higher Education“Bashkir State Agrarian University”UfaRussia

This article is devoted to the study of the system of indicators characterizing thevolume, structure and efficiency of the functioning of fixed assets of theproduction and non-production areas of the region based on the index *** factorial index analysis, models of the relationship between the grossregional product, the cost of fixed assets and capital productivity (capitalintensity) of industries producing goods and providing services were obtained,to identify reserves for increasing of the analyzed indicators. The obtainedresults indicate a trend towards significant decrease in capital productivity inthe production sector, which should become the basis for making managerialdecisions at the regional level to attract investment. They can be used in thepractice of macroeconomic analysis and forecasting, for detailing the factors fordetermining the potential of economic sectors, the efficiency of using fixedassets, and attracting investments.

关键词： gross regional product factor index analysis capital productivity capital intensity

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A cross-sectional study of post-COVID syndrome at a tertiary care center in Turkey

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Asian Pacific Journal of Tropical Medicine 2022年第9期15卷 410-417页

作者： Efraim guzel Oya Baydar Toprak Burak Mete Yasemin Saygıdeger Bengu Curuk Sedat Kuleci Cukurova University Faculty of MedicineDepartment of Chest DiseasesAdanaTurkey Cukurova University Faculty of MedicineDepartment of Public HealthAdanaTurkey

Objective:To investigate long-term symptoms after acute COVID-19,the link between symptoms and respiratory function,radiological changes in the post-COVID period,and risk factors for post-COVID ***:In this cross-sectional study,123 participants who were admitted within the first 3 months were categorized as group 1,and those who applied after 3 months were categorized as group *** to thoracic imaging and pulmonary function tests,patients were split into 3 groups as mild,moderate and ***:At least one symptom was present in 91.9%and 61.8%in acute and post-COVID period,*** function tests were normal in 60(70.6%)in the first three months,and 30(78.9%)in 91-days to 1-year period after acute COVID-19 *** 3 months,22.4%of chest X-rays and 7.9%of computerized tomography revealed *** who developed acute complications(OR 9.91,95%CI 1.93-50.87),had 2 or more symptoms at admission(OR 7.73,95%CI 2.56-23.33),had 1%to 14%CT involvement(OR 3.05,95%CI 1.06-8.79),or had 50%or more CT involvement(OR 14.68,95%CI 1.24-172.55)had a higher risk of developing post-COVID ***:COVID-19 symptoms can last for long *** of symptoms,acute complications,and the extent of radiological involvement may all contribute to elevated risk of post-COVID *** a result,patients with COVID-19 should be checked for long-term clinical difficulties on regular basis.

关键词： Post-COVID syndrome COVID-19 Symptoms Pulmonary function tests Risk factors

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Effects of hyperbaric oxygen and Pgg-glucan on ischemic colon anastomosis

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World Journal of Gastroenterology 2006年第9期12卷 1421-1425页

作者： Suna guzel Oguzhan Sunamak Abdullah AS Varol Celik Mehmet Ferahman Muhammed MK Nuri Ertugrul Gazioglu Pinar Atukeren Ozgur Mutlu Department of General Surgery Cerrahpasa Faculty of Medicine IstanbulTurkey Department of Biochemistry Cerrahpasa Faculty of Medicine IstanbulTurkey Department of Underwater and Hyperbaric Oxygen Istanbul Faculty of Medicine IstanbulTurkey

AIM： In colorectal surgery, anastomotic failure is still a problem in ischemia. Here, we analyzed the effects of hyperbaric oxygen and beta-glucan on colon anastomoses in ischemic condition. METHODS： Colonic resection and anastomosis in rectosigmoid region were done in forty Wistar-Albino rats of four groups of equal number. Colon mesentery was ligated to induce ischemia. The first group was the control group. The subjects of second group were treated with hyperbaric oxygen; the third group with glucan and the forth group were treated with both. At the forth day, rats were sacrificed, anastomotic segment was resected and burst pressures and hydroxyproline levels of anastomotic line were measured. RESULTS： The burst pressure difference of second and third groups from the control group were meaningful （P〈0.01）; the forth group differed significantly from the control （P〈0.001）. There was no difference between the treated groups on burst pressure level （P〉0.05）. The hydroxyproline levels in all treated groups were different from the control group significantly （P〈0.001）. Hydroxyproline levels in the forth group were higher than those of the second and the third groups （P〈 0.001）. There were no significant differences between the second and the fourth groups in burst pressure and hydroxyproline levels （P〉 0.05）. CONCLUSION： Hyperbaric oxygen and glucan improve healing in ischemic colon anastomoses by anti-microbic,immune stimulating properties and seem to act synergistically when combined together.

关键词： Anastomosis Ischemic colon Hyperbaric oxygen PGG-Glucan

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Silica-based nanoarchitecture for an optimal combination of photothermal and chemodynamic therapy functions of Cu2–xS cores with red emitting carbon dots

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Frontiers of Chemical Science and Engineering 2023年第12期17卷 2144-2155页

作者： Alexey Stepanov Svetlana Fedorenko Kirill Kholin Irek Nizameev Alexey Dovzhenko Rustem Zairov Tatiana Gerasimova Alexandra Voloshina Anna Lyubina guzel Sibgatullina Dmitry Samigullin Asiya Mustafina Arbuzov Institute of Organic and Physical Chemistry FRC Kazan Scientific Center of RASKazan 420088Russia Department of Physics Kazan National Research Technological UniversityKazan 420015Russia Department of Nanotechnology in Electronics Kazan National Research Technical University named after A.N.Tupolev-KAIKazan 420111Russia Kazan(Volga region)Federal University Kazan 420008Russia Kazan Institute of Biochemistry and Biophysics FRC Kazan Scientific Center of RASKazan 420111Russia

This study introduces multifunctional silica nanoparticles that exhibit both high photothermal and chemodynamic therapeutic activities,in addition to *** activity of the silica nanoparticles is derived from their plasmonic properties,which are a result of infusing the silica nanoparticles with multiple Cu2-xS *** infusion process is facilitated by a recoating of the silica nanoparticles with a cationic *** key factors that enable the internal incorporation of the Cu2-xS cores and the external deposition of red-emitting carbon dots are *** Cu2-xS cores within the silica nanoparticles exhibit both self-boosting generation of reactive oxygen species and high photothermal conversion efficacy,which are essential for photothermal and chemodynamic *** silica nanoparticles’small size(no more than 70 nm)and high colloidal stability are prerequisites for their cell *** internalization of the red-emitting silica nanoparticles within cells is visualized using fluorescence microscopy *** chemodynamic activity of the silica nanoparticles is associated with their dark cytotoxicity,and the mechanisms of cell death are evaluated using an apoptotic *** photothermal activity of the silica nanoparticles is demonstrated by significant cell death under near-infrared(1064 nm)irradiation.

关键词： copper sulfide nanoparticles chemodynamic therapy photothermal therapy carbon dots silica nanoparticles

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