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Mental health status among COVID-19 patients survivors of critical illness in Saudi Arabia:A 6-month follow-up questionnaire study

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World Journal of Clinical Cases 2024年第15期12卷 2560-2567页

作者： Abdullah M Alhammad Namareq F Aldardeer Abdulaziz Alqahtani Mohammad H Aljawadi Bushra Alnefaie Raghad Alonazi Mansour Almuqbil Abdulrahman Alsaadon Rakan M Alqahtani rashid Alballaa Bader Alshehri Mohammed I Alarifi Fahad D Alosaimi Department of Clinical Pharmacy College of PharmacyKing Saud UniversityRiyadh 12372Saudi Arabia Department of Pharmacy Services King Faisal Specialist Hospital and Research CentreJeddah 21499Saudi Arabia Corporate Department of Pharmacy Services King Saud University Medical CityRiyadh 12372Saudi Arabia College of Pharmacy King Saud UniversityRiyadh 12372Saudi Arabia Department of Critical Care Medicine College of MedicineKing Saud UniversityRiyadh 12372Saudi Arabia Department of Psychiatry College of MedicineKing Saud UniversityRiyadh 12372Saudi Arabia

BACKGROUND Psychological assessment after intensive care unit(ICU)discharge is increasingly used to assess patients'cognitive and psychological ***,few studies have examined those who recovered from coronavirus disease 2019(COVID-19).There is a paucity of data from the Middle East assessing the post-ICU discharge mental health status of patients who had *** To evaluate anxiety and depression among patients who had severe *** This is a prospective single-center follow-up questionnaire-based study of adults who were admitted to the ICU or under ICU consultation for>24 h for *** patients were contacted via *** patient’s anxiety and depression six months after ICU discharge were assessed using the Hospital Anxiety and Depression Scale(HADS).The primary outcome was the mean HADS *** secondary outcomes were risk factors of anxiety and/or *** Patients who were admitted to the ICU because of COVID-19 were screened(n=518).Of these,48 completed the *** mean age was 56.3±17.2 *** patients(62.5%)were *** main comorbidities were endocrine(n=24,50%)and cardiovascular(n=21,43.8%)*** mean overall HADS score for anxiety and depression at 6 months post-ICU discharge was 11.4(SD±8.5).A HADS score of>7 for anxiety and depression was detected in 15 patients(30%)and 18 patients(36%),*** from the multivariable ordered logistic regression demonstrated that vasopressor use was associated with the development of anxiety and depression[odds ratio(OR)39.06,95% confidence interval:1.309-1165.8;P<0.05].CONCLUSION Six months after ICU discharge,30% of patients who had COVID-19 demonstrated a HADS score that confirmed anxiety and *** compare the psychological status of patients following an ICU admission(with vs without COVID-19),further studies are warranted.

关键词： COVID-19 Critically ill Anxiety Depression HADS Saudi Arabia

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The diagnostic conundrum in necrotizing otitis externa

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 59-65页

作者： Abiya A.Ahmed Shaan rashid Vinay K.Gupta Neil C.Molony Keshav K.Gupta Bradford Royal Infirmary Bradford Teaching Hospitals NHS Foundation TrustWest BromwichWest YorkshireUK Sandwell and West Birmingham Hospitals NHS Trust West BromwichUK Russells Hall Hospital DudleyUK

Necrotizing otitis externa(NOE)is an aggressive and fast‐evolving infection of the external auditory *** diagnoses and untreated cases can lead to severe,even fatal consequences and so early diagnosis and treatment are *** is a notoriously challenging diagnosis to *** is therefore important to understand what diagnostic modalities are available and how otolaryngologists can use them to accurately treat such an aggressive *** review aims to evaluate the different diagnostic options available in NOE and discuss their advantages and limitations,thus,providing an up‐to‐date picture of the multimodal approach required in the diagnosis of this disease.

关键词： diagnostic malignant otitis externa necrotizing osteomyelitis skull base osteomyelitis temporal bone osteomyelitis

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Credit Card Fraud Detection Using Machine Learning Techniques

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Journal of Computer and Communications 2024年第6期12卷 1-11页

作者： Ananya Sarker Must. Asma Yasmin Md. Atikur Rahman Md. Harun Or rashid Bristi Rani Roy Department of Computer Science and Engineering Bangladesh Army University of Engineering & Technology (BAUET) Natore Bangladesh

Credit card companies must be able to identify fraudulent credit card transactions so that clients are not charged for items they did not purchase. Previously, many machine learning approaches and classifiers were used to detect fraudulent transactions. However, because fraud patterns are always changing, it is becoming increasingly vital to investigate new frauds and develop the model based on the new patterns. The purpose of this research is to create a machine learning classifier that not only detects fraud but also detects legitimate transactions. As a result, the model should have excellent accuracy, precision, recall, and f1-score. As a result, we began with a large dataset in this study and used four machine learning classifiers: Support Vector Machine (SVM), Decision Tree, Naïve Bayes, and Random Forest. The random forest classifier scored 99.96% overall accuracy with the best precision, recall, f1-score, and Matthews correlation coefficient in the experiments.

关键词： Support Vector Machine Decision Tree Nave Bayes Random Forest Matthews Correlation

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Clinicopathological features and medium-term outcomes of histologic variants of primary focal segmental glomerulosclerosis in adults:A retrospective study

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World Journal of Nephrology 2024年第1期13卷 14-24页

作者： Nazarul Hassan Jafry Shumaila Manan Rahma rashid Muhammed Mubarak Department of Nephrology Sindh Institute of Urology and TransplantationSindhKarachi 74200Pakistan Department of Pathology Sindh Institute of Urology and TransplantationSindhKarachi 74200Pakistan

BACKGROUND The Columbia classification identified five histological variants of focal segmental glomerulosclerosis(FSGS).The prognostic significance of these variants remains *** To evaluate the relative frequency,clinicopathologic characteristics,and medium-term outcomes of FSGS variants at a single center in *** This retrospective study was conducted at the Department of Nephrology,Sindh Institute of Urology and Transplantation,Karachi,Pakistan on all consecutive adults(≥16 years)with biopsy-proven primary FSGS from January 1995 to December *** subjects were treated with steroids as a first-line *** response rates,doubling of serum creatinine,and kidney failure(KF)with replacement therapy were compared between histological variants using ANOVA or Kruskal Wallis,and Chi-square tests as *** were analyzed by SPSS version 22.0.P-value≤0.05 was considered *** A total of 401 patients were diagnosed with primary FSGS during the study *** these,352(87.7%)had a designated histological *** not otherwise specified(NOS)variant was the commonest,being found in 185(53.9%)patients,followed by the tip variant in 100(29.1%)***(COL),cellular(CEL),and perihilar(PHI)variants were seen in 58(16.9%),6(1.5%),and 3(0.7%)patients,*** and PHI variants were excluded from further analysis due to small patient *** mean follow-up period was 36.5±29.2 *** response rates of variants,patients with TIP lesions achieved remission more frequently(59.5%)than patients with NOS(41.8%)and COL(24.52%)variants(P<0.001).The hazard ratio of complete response among patients with the COL variant was 0.163[95%confidence interval(CI):0.039-0.67]as compared to patients with *** TIP variant showed a hazard ratio of 2.5(95%CI:1.61-3.89)for complete remission compared to the NOS ***,progressive KF was observed more frequently in patients with the COL variant,43.

关键词： Adults Columbia classification Focal segmental glomerulosclerosis Histological variants Kidney failure Kidney failure with replacement therapy

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Outcome of bariatric surgery in patients with unexpected liver cirrhosis: A multicenter study from China

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Liver Research 2024年第3期8卷 172-178页

作者： Xia Sun Libin Yao Xing Kang Weihua Yu Fidele Kakule Kitaghenda Mohammad Sajjad Ibn rashid Angeline Nogue Taguemkam Jian Hong Zhiyong Dong Xitai Sun Xiaocheng Zhu Department of Gastrointestinal Surgery The Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsuChina Department of Pancreatic and Metabolic Surgery Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsuChina Department of General Surgery Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhouZhejiangChina Department of Metabolic and Bariatric Surgery The First Affiliated Hospital of Jinan UniversityGuangzhouGuangdongChina

Background and aims Liver cirrhosis is a complex disease that may result in increased morbidity and mortality following bariatric surgery(BS).This study aimed to explore the outcome of BS in patients with unexpected cirrhosis,focusing on postoperative complications and the progression of liver *** A retrospective study of bariatric patients with cirrhosis from four centers in China between 2016 and 2023 was conducted,with follow-up for one year after *** primary outcome was the safety of BS in patients with unexpected cirrhosis,while the secondary outcome was the metabolic efficacy of BS in this group *** A total of 47 patients met the study criteria,including 46 cases of Child-Pugh class A cirrhosis and 1 case of Child-Pugh *** examination confirmed nodular cirrhosis in 21 patients(44.68%),pseudolobule formation in 1 patient(2.13%),lipedema degeneration with inflammatory cell infiltration in 3 patients(6.38%),and chronic hepatitis in 1 patient(2.13%).The average percentage of total weight loss was 29.73±6.53%at one year *** the 30-day postoperative period,the complication rate was 6.38%,which included portal vein thrombosis,gastrointestinal bleeding,and intra-abdominal ***,no cases of liver decompensation or mortality were reported during the follow-up *** remission rates of comorbidities among 41 patients one year after surgery were as follows:dyslipidemia 100%,type 2 diabetes 82.61%,hypertension 84.62%,and obstructive sleep apnea syndrome 85.71%.Conclusions BS can be safely performed in patients with unexpected cirrhosis in the compensated stage of liver disease,with low postoperative morbidity and no mortality observed during one-year follow-up.

关键词： Bariatric surgery(BS) Metabolic surgery Liver cirrhosis Obesity Type 2 diabetes mellitus(T2M)

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Profiling Casualty Severity Levels of Road Accident Using Weighted Majority Voting

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Computers, Materials & Continua 2022年第6期71卷 4609-4626页

作者： Saba Awan Zahid mehmood Hassan Nazeer Chaudhry Usman Tariq Amjad Rehman Tanzila Saba Muhammad rashid Department of Software Engineering University of Engineering and TechnologyTaxila47050Pakistan Department of Computer Engineering University of Engineering and TechnologyTaxila47050Pakistan Department of Electronics Information and BioengineeringPolitecnico di MilanoMilano20122Italy College of Computer Engineering and Sciences Prince Sattam bin Abdulaziz UniversityAl-Kharj11942Saudi Arabia College of Computer and Information Sciences Prince Sultan UniversityRiyadhSaudi Arabia Department of Computer Engineering Umm Al-Qura UniversityMakkah21421Saudi Arabia

To determine the individual circumstances that account for a road traffic accident,it is crucial to consider the unplanned connections amongst various factors related to a crash that results in high casualty *** of the road accident data concentrated mainly on categorizing accidents into different types using individually built classification methods which limit the prediction accuracy and fitness of the *** this article,we proposed a multi-model hybrid framework of the weighted majority voting(WMV)scheme with parallel structure,which is designed by integrating individually implemented multinomial logistic regression(MLR)and multilayer perceptron(MLP)classifiers using three different accident datasets i.e.,IRTAD,NCDB,and *** proposed WMV hybrid scheme overtook individual classifiers in terms of modern evaluation measures like ROC,RMSE,Kappa rate,classification accuracy,and performs better than state-of-theart approaches for the prediction of casualty severity ***,the proposed WMV hybrid scheme adds up to accident severity analysis through knowledge representation by revealing the role of different accident-related factors which expand the risk of casualty in a road *** aspects related to casualty severity recognized by the proposed WMV hybrid approach can surely support the traffic enforcement agencies to develop better road safety plans and ultimately save lives.

关键词： Prediction hybrid framework severity class casualty

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Synthesis and characterization of poppy seed oil methyl esters

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Chinese Journal of Chemical Engineering 2016年第8期24卷 1087-1096页

作者： Umer rashid Muhammad Ibrahim Imededdine Arbi Nehdi Saud Ibrahim Al-Resayes Sammi Ullah Muhammad Aamer mehmood Saira Shahzadi Institute of Advanced Technology Universiti Putra Malaysia Chemistry Department College of Science King Saud University Department of Environmental Sciences & Engineering Faculty of Engineering Government College University Faisalabad Department of Chemistry Government College University Faisalabad Department of Bioinformatics & Biotechnology Government College University Faisalabad Department of Chemistry Quaid-i-Azam University

Response surface methodology(RSM) was used to determine the optimum conditions of the methanolysis of crude poppy seed oil using Na OCH3 as catalyst. The experiments were run according to five levels, four variable central composite rotatable design(CCRD) using RSM. The reaction variables, i.e., molar ratio of methanol/oil(3:1–9:1), catalyst concentration(0.5 wt%–1.25 wt% Na OCH3), reaction temperature(25–65 °C), and reaction time(20–90 min) were studied. We demonstrated that the molar ratio of methanol/oil, catalyst concentration,and reaction temperature were the significant parameters affecting the yield of poppy seed oil methyl esters(PSOMEs). The optimum transesterification reaction conditions, established using the RSM, which offered a89.35% PSOME yield, were found to be 7.5:1 molar ratio of methanol/oil, 0.75% catalyst concentration, 45 °C reaction temperature, and 90 min reaction time. The proposed process provided an average biodiesel yield of more than 85%. A linear correlation was constructed between the observed and predicted values of the *** gas chromatography(GC) analyses have shown that PSOMEs contain linoleic-, oleic-, palmitic-, and stearic-acids as main fatty acids. The FTIR spectrum of the PSOMEs was also analyzed to confirm the completion of the transesterification reaction. The fuel properties of the PSOMEs were discussed in light of biodiesel standards(ASTM D 6751 and EN 14214).

关键词： Poppy oil Optimization Gas chromatography FTIR Fuel properties

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Extracellular vesicles as tools and targets in therapy for diseases

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Signal Transduction and Targeted Therapy 2024年第3期9卷 872-912页

作者： Mudasir A.Kumar Sadaf K.Baba Hana Q.Sadida Sara Al.Marzooqi Jayakumar Jerobin Faisal H.Altemani Naseh Algehainy Mohammad A.Alanazi Abdul-Badi Abou-Samra Rakesh Kumar Ammira S.Al-Shabeeb Akil Muzafar A.Macha rashid Mir Ajaz A.Bhat Watson-Crick Centre for Molecular Medicine Islamic University of Science and TechnologyAwantiporaKashmir 192122India Department of Human Genetics-Precision Medicine in Diabetes Obesity and Cancer ProgramSidra MedicineDohaQatar Qatar Metabolic Institute Academic Health SystemHamad Medical CorporationDohaQatar Department of Medical Laboratory Technology Prince Fahad Bin Sultan Chair for Biomedical ResearchFaculty of Applied Medical SciencesUniversity of TabukTabukSaudi Arabia School of Biotechnology Shri Mata Vaishno Devi UniversityKatraIndia

Extracellular vesicles(EVs)are nano-sized,membranous structures secreted into the extracellular *** exhibit diverse sizes,contents,and surface markers and are ubiquitously released from cells under normal and pathological *** serum is a rich source of these EVs,though their isolation from serum proteins and non-EV lipid particles poses *** vesicles transport various cellular components such as proteins,mRNAs,miRNAs,DNA,and lipids across distances,influencing numerous physiological and pathological events,including those within the tumor microenvironment(TME).Their pivotal roles in cellular communication make EVs promising candidates for therapeutic agents,drug delivery systems,and disease *** in cancer diagnostics,EV detection can pave the way for early identification and offers potential as diagnostic ***,various EV subtypes are emerging as targeted drug delivery tools,highlighting their potential clinical *** need for non-invasive biomarkers to monitor biological processes for diagnostic and therapeutic purposes remains *** into the unique composition of EVs could unlock advanced diagnostic and therapeutic avenues in the *** this review,we discuss in detail the roles of EVs across various conditions,including cancers(encompassing head and neck,lung,gastric,breast,and hepatocellular carcinoma),neurodegenerative disorders,diabetes,viral infections,autoimmune and renal diseases,emphasizing the potential advancements in molecular diagnostics and drug delivery.

关键词： diseases sized sizes

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艾滋病病毒流行重组毒株CRF01_AE及其影响

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中国艾滋病性病 2024年第1期30卷 79-83页

作者：李斯斯李康 Abdur rashid 贺江珊王沛葭刘茂顺冯毅邵一鸣广西艾滋病防治研究重点实验室公共卫生学院广西医科大学南宁530021 中国疾病预防控制中心性病艾滋病预防控制中心北京102206 南开大学天津300071 北京师范大学北京100875

CRF01_AE作为HIV最主要的流行重组毒株,在全球范围长时序演变,形成区域间的流行特征,构成特色且独立的流行与传播模式,本文从其起源、遗传多样性、流行特征及其对诊断和治疗延迟、疾病进程、治疗效果影响等方面进行综述,阐释CRF01_AE及... 详细信息

CRF01_AE作为HIV最主要的流行重组毒株,在全球范围长时序演变,形成区域间的流行特征,构成特色且独立的流行与传播模式,本文从其起源、遗传多样性、流行特征及其对诊断和治疗延迟、疾病进程、治疗效果影响等方面进行综述,阐释CRF01_AE及时监测对遏制HIV区域间和全球蔓延的作用。

关键词：艾滋病亚型重组流行病学

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National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma

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World Journal of Gastroenterology 2024年第9期30卷 1018-1042页

作者： Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Haider Syed Mujahid Hassan Adnan Abdul Jabbar Aman Nawaz Khan Muhammad Shoaib Khan Muhammad Yasir Khan Amer Latif Nasir Hassan Luck Ahmad Karim Malik Kamran rashid Sohail rashid Mohammad Salih Abdullah Saeed Amjad Salamat Ghias-un-Nabi Tayyab Aasim Yusuf Haseeb Haider Zia Ammara Naveed Department of Hepatopancreatic Biliary Surgery&Liver Transplant Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Hepatogastroenterology and Liver Transplantation Dr.Ziauddin University HospitalKarachi 75600SindhPakistan University of Aberdeen Aberdeen B243FXUnited Kingdom Department of Pathology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Gastroenterology&Hepatology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Radiology Aga Khan UniversityKarachi 74800Pakistan Department of Oncology Hameed Latif HospitalLahore 54000Pakistan Division of Hepatopancreatic Biliary Surgery&Liver Transplantation Shifa International HospitalIslamabad 44000Pakistan Department of Hepatopancreatic Biliary Surgery&Liver Transplant Shaikh Zayed Hospital and Post Graduate Medical InstituteLahore 54000Pakistan Department of Medicine Aga Khan University HospitalKarachi 74800Pakistan Department of Liver Transplant Pir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Medicine&Gastroenterology Lifecare Hospital and Research CentrePeshawar 25000Khyber PakhtunkhwaPakistan Department of Hepatopancreatobiliary&Liver Transplant Bahria International HospitalLahore 54000Pakistan Department of Surgery Hepatopancreatobiliary&Liver TransplantDow University of Health SciencesKarachi 74800Pakistan Department of Gastroenterology Hepatology&NutritionPir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Oncology Dr.Ziauddin HospitalKarachi 74800Pakistan Department of Radiology Rehman Medical InstitutePeshawar 25000Pakistan Army Liver Transplant Unit Pak Emirates Military HospitalRawalpindi 46000Pakistan Department of Gastroenterology Sindh Institute of Urology and TransplantationKarachi 75500Pakistan rashid Nursing Home and Cancer Clinic Rashid Nursing Home and Cancer ClinicRawalpindi 46000Pakistan Department of Gastroentero

A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the *** Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this *** effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these *** coordinated effort can minimise delays and give patients a chance for curative treatment and effective *** diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance *** cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for ***,histopathologic confirmation is not always required before *** ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for *** only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette *** patients with unresectable hCCA can be considered for liver *** chemotherapy should be offered to patients with a high risk of *** use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary *** with acute cholangitis can be drained with endoscopic or percutaneous biliary *** chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA.

关键词： Hilar cholangiocarcinoma Bismuth-Corlette classification Memorial Sloan Kettering Cancer Centre Staging Preoperative biliary drainage Portal vein embolisation Surgical resection Hepatectomy

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