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Dendritic cell co-stimulatory and co-inhibitory markers in chronic HCV: An Egyptian study

World Journal of Gastroenterology 2013年第43期19卷 7711-7718页

作者： Hanan Fouad Maissa Saeed El Raziky rasha ahmed abdel aziz Dina Sabry Ghada Mahmoud abdel aziz Manal Ewais ahmed Reda Sayed Medical Biochemistry Department Faculty of MedicineCairo University11562 CairoEgypt Gastroenterology and Tropical Department Faculty of MedicineCairo University11562 CairoEgypt Medical Biochemistry Department Faculty of MedicineBeni Sueif University19206 Kornish Al NileBani SweifEgypt

AIM:To assess co-stimulatory and co-inhibitory markers of dendritic cells(DCs)in hepatitis C virus(HCV)infected subjects with and without ***:Three subject groups were included in the study:group 1 involved 50 control subjects,group2 involved 50 patients with chronic HCV infection and group 3 involved 50 HCV uremic subjects undergoing ***83,CD86 and CD40 as co-stimulatory markers and PD-L1 as a co-inhibitory marker were assessed in peripheral blood mononuclear cells by realtime polymerase chain ***-10(IL-10)and hyaluronic acid(HA)levels were also *** findings were correlated with disease activity,viral load and ***:There was a significant decrease in costimulatory markers;CD83,CD86 and CD40 in groups2 and 3 vs the control ***-stimulatory markers were significantly higher in group 3 vs group *** was a significant elevation in PD-L1 in both HCV groups vs the control ***-L1 was significantly lower in group 3 vs group *** was a significant elevation in IL-10 and HA levels in groups 2 and 3,where IL-10was higher in group 3 and HA was lower in group 3 vs group *** level was significantly correlated with disease activity and fibrosis grade in group ***-10 was significantly correlated with fibrosis grade in group *** were significant negative correlations between co-stimulatory markers and viral load in groups 2 and3,except CD83 in dialysis *** was a significant positive correlation between PD-L1 and viral load in both HCV ***:A significant decrease in DC co-stimulatory markers and a significant increase in a DC coinhibitory marker were observed in HCV subjects and to a lesser extent in dialysis patients.

关键词： Hepatitis C virus Uremia Hemodialysis Dendritic cells CD83 CD86,CD40 PD-L1 Interleukin-10 Hyaluronic acid

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Electromagnetic effects on the orbital motion of a charged spacecraft

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Research in Astronomy and Astrophysics 2014年第5期14卷 589-600页

作者： Yehia ahmed abdel-aziz Khalil Ibrahim Khalil National Research Institute of Astronomy and Geophysics (NRIAG) Helwan Cairo 11721Egypt Department of Mathematics Hail University Hail 2440 Kingdom of Saudi Arabia

This paper deals with the effects of electromagnetic forces on the orbital motion of a spacecraft. The electrostatic charge which a spacecraft generates on its surface in the Earth＇s magnetic field will be subject to a perturbative Lorentz force. A model incorporating all Lorentz forces as a function of orbital elements has been developed on the basis of magnetic and electric fields. This Lorentz force can be used to modify or perturb the spacecraft＇s orbits. Lagrange＇s planetary equations in the Gauss variational form are derived using the Lorentz force as a perturbation to a Keplerian orbit. Our approach incorporates orbital inclination and the true anomaly. The numer- ical results of Lagrange＇s planetary equations for some operational satellites show that the perturbation in the orbital elements of the spacecraft is a second order perturba- tion for a certain value of charge. The effect of the Lorentz force due to its magnetic component is three times that of the Lorentz force due to its electric component. In addition, the numerical results confirm that the strong effects are due to the Lorentz force in a polar orbit, which is consistent with realistic physical phenomena that occur in polar orbits. The results confirm that the magnitude of the Lorentz force depends on the amount of charge. This means that we can use artificial charging to create a force to control the attitude and orbital motion of a spacecraft.

关键词： space vehicles -- atmospheric effects -- celestial mechanics -- kine-matics and dynamics

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Rescue effects of aqueous seed extracts of Foeniculum vulgare and Carum carvi against cadmium-induced hepatic, renal and gonadal damage in female albino rats

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Asian Pacific Journal of Tropical Medicine 2017年第12期10卷 1123-1133页

作者： ahmed abdel-Wahab abdel-Razik Hashem abdel-Razik Rabie Lotfy abdel aziz Physiology Department Faculty of Veterinary MedicineMinia University61519 El-MiniaEgypt Histology Department Faculty of Veterinary MedicineBeni-Suef University62512 Beni-SuefEgypt Department of Theriogenology Faculty of Veterinary MedicineBeni-Suef University62512 Beni-SuefEgypt

Objective: To investigate the protective effects of aqueous seed extracts of fennel"Foeniculum vulgare"(FVE) and caraway "Carum carvi"(CCE) on liver, kidney and reproductive organs in female rats against cadmium chloride(CC) ***: A total of 36 adult female rats were divided into six groups, six in each *** group(fed normal diet), CC-treated group(50 mg CC/kg diet), CCE-treated group(150 mg CCE/kg diet), CCE + CC group, FVE(150 mg/kg diet) and FVE + CC. One month later, all rats were sacrificed and all samples were collected at proestrus ***: The toxic effects of CC were confirmed biochemically by significant increase of serum concentration of liver enzymes(P < 0.05), and creatinine(P < 0.001). Moreover,CC increased significantly the serum level of malondialdehyde(MDA) and decreased the total antioxidant capacity(TAC)(P < 0.001). In addition, serum concentrations of estrogen, progesterone, follicle-stimulating hormone(FSH) and luteinizing hormone(LH)were significantly decreased(P < 0.01). Histopathologically, CC-treated group revealed marked pathological changes in renal, hepatic, ovarian and uterine tissues. All toxic findings observed in liver and kidney with CC treatment were found to be ameliorated markedly after co-treatments with FVE or CCE. Furthermore, co-treatment of FVE with CC improved significantly all studied reproductive parameters(P < 0.01).Conclusions: Both FVE and CCE could be used as efficient treatments for liver and kidney against CC intoxication. Moreover, FVE could be utilized as a potent treatment to protect and improve female fertility from cadmium intoxication.

关键词： Cadmium Carum carvi Foeniculum vulgare Liver Kidney Fertility

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Antifouling evaluation of extracts from Red Sea soft corals against primary biofilm and biofouling

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Asian Pacific Journal of Tropical Biomedicine 2017年第11期7卷 991-997页

作者： Yosry abdel aziz Soliman ahmed Mohammed Brahim ahmed Hussein Moustafa Mohamed abdel Fattah Hamed Marine Chemistry Lab. Marine Environment DivisionNational Institute of Oceanography and FisheriesSuezEgypt Department of Chemistry Faculty of ScienceZagazig UniversityZagazigEgypt

Objectives: To evaluate antifouling property of extracts from Red Sea soft corals against primary biofilm and ***: Seven species of soft corals Sarcophyton glaucum(a), Sinularia compressa,Sinularia cruciata(a), Heteroxenia fuscescens(a), Sarcophyton glaucum(b), Heteroxenia fuscescens(b) and Sinularia cruciata(b) were chosen to test their extracts as antibacterial and antifouling agents in Eastern Harbour of Alexandria, Mediterranean *** compounds of soft corals were extracted by using methanol and concentrated under vacuum. The residues of extracts were mixed in formulation of inert paint which consisted of rosin, chlorinated rubber and ferrous oxide against micro and macro fouling organisms. The formulated paints were then applied on PVC panels twice by brush,hanged in a steel frame and immersed in Eastern Harbour of Alexandria Mediterranean Sea followed by visual inspection and photographic ***: After 185 days of immersion in seawater, the antifouling results agreed with the antibacterial results where extracts of Sinularia compressa and Heteroxenia fuscescens(b) gave the best activity against marine fouling tubeworms and barnacles. The inhibition activity was correlated with the major functional groups(hydroxyl, amino, carbonyl,aliphatic(fatty acids), C]C of alkene or aromatic rings and CeC l of aryl halides) of the ***: The strong antifouling activity makes them promising candidates for new antifouling additives. After the screening and application of natural organic compounds from soft corals, marine organisms show activity against micro and macro fouling organisms.

关键词： Antibacterial Antifouling Paints Seawater Marine Organisms

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Relationship between heart girth, serum progesterone and superovulation response ofdonor Holstein cows

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Asian pacific Journal of Reproduction 2019年第3期8卷 118-123页

作者： abdel-Tawab AYKhalil ahmed abdel-Wahab Rabie Labdel aziz Department of Theriogenology Faculty of Veterinary MedicineBeni-Suef UniversityBeni-SuefEgypt Physiology Department Faculty of Veterinary MedicineMinia UniversityEl-MiniaEgypt

Objective: To determine effects of variations of heart girth, volume trait on embryo quality grade, and to explore the relationship between heart girth and circulating progesterone and correlations of circulating progesterone with embryo quality grade in superstimulated donor Holstein cows. Methods: Nineteen cows were subjected to a standard superstimulation protocol using follicle stimulating hormone. Blood samples were collected before superovulation, at insemination and at collection of embryos for progesterone analysis. Embryo quality grades were compared between high and low heart girth donors. Moreover, Pearson's correlations were determined between heart girth, progesterone and embryo quality. Results: Variation of heart girth was not associated with significant differences in embryo quality grade between high and low heart girth donor cows (P>0.05). However, we observed a significantly higher percentage of the third-grade embryo (24.09%) in low heart girth donors compared to 9.64% in high heart girth donors. Moreover, the percentage of the transferable embryo was numerically higher and that of the degenerated embryo was numerically lower in low heart girth cows. Donor cows with low response to superovulation (total structures ≤ 3) expressed numerically higher mean heart girth, compared to donors with high (total structures>15) and medium (total structures = 4-15) superovulation. Heart girth and body weight of donor cows were moderately correlated (r=0.45, P<0.05), but none was correlated with circulating progesterone at different sampling times except for a moderate correlation between body weight and progesterone at embryo collection (r=0.54, P=0.02). Circulating progesterone before superovulation was moderately correlated to the second-grade embryo (r=0.46, P<0.05) and to the third grade (r=0.52, P<0.05) embryo. Conclusions: Volume traits heart girth may influence the response of Holstein cows to superovulation;however, future studies with a higher number

关键词： Heart girth Superovulation Embryo quality Progesterone Holstein cow

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Cartilage tympanoplasty in the treatment of adhesive otitis media with and without Eustachian tube balloon dilatation

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Journal of Otology 2022年第4期17卷 226-231页

作者： ahmed abdel rahman abdel aziz ahmed Mahmoud Youssef Mostafa Mohamed Mostafa Mostafa talaat Khaled Mohamed abdelzaher ahmed Adel Sadeq Department of Otorhinolaryngology Faculty of MedicineEl MiniaEgypt Radiology Department Faculty of MedicineEl MiniaEgypt

Purpose:To compare cartilage tympanoplasty(CT)combined with eustachian tube balloon dilatation(ETBD)and cartilage tympanoplasty alone as a surgical treatment modality for adhesive otitis media(AdOM)in terms of graft healing,audiological outcomes,and impact on life style,using Chronic Otitis Media Outcome Test 15(COMOT-15).Methods:50 patients with AdOM were randomly classified into 2 groups:25 patients for cartilage tympanoplasty only(CT group)and 25 patients for cartilage tympanoplasty combined with eustachian tube balloon dilatation(CT t ETBD group).Clinical outcomes in both groups were compared at 3 and 6 months of follow ***:There was no significant difference in graft healing between the two *** COMOT-15 scores significantly decreased in both groups with a significant difference between the groups with regard to the decrease in COMOT-15 scores at 3 and 6 months of follow-up(P<0.05).Hearing improvement was achieved,as the mean preoperative ABG was 26.5±5.4 and 27.1±4.6 dB,and the mean postoperative ABG at 6 months was 19.4±4.4 and 14.6±3.9 dB in the CT and the CT t ETBD groups,*** difference in the magnitude of ABG reduction in the two groups was significant at 3 and 6 months of postoperative follow-up(P<0.05)in favour of the CT t ETBD ***:ETBD can increase the success rate of cartilage tympanoplasty in patients with AdOM by enhancing the audiological outcome and quality of life.

关键词： balloon healing otitis

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Types of trematodes infecting freshwater snails found in irrigation canals in the East Nile locality,Khartoum,Sudan

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Infectious Diseases of Poverty 2016年第1期5卷 139-148页

作者： Nidal A.I.Mohammed Henry Madsen abdel aziz A.R.M.ahmed Department of Zoology Khartoum College of Medical SciencesKhartoumSudan Parasitology and Aquatic Diseases Department of Veterinary Disease BiologyFaculty of Health and Medical SciencesUniversity of CopenhagenFrederiksbergDenmark Education Expert Company RiyadhKingdom of Saudi Arabia

Background:The planorbid freshwater snails of the two genera,Biomphalaria and Bulinus-have been vigorously studied due to the role they play as intermediate hosts of *** Sudan specifically,most studies have focused on the chemical and ecological control of the two genera,but few studies have looked at their biological *** study explored the coexistence of other species of freshwater snails and the two genera along with their trematode infections in relation to a number of environmental factors in the East Nile locality,Khartoum state,***:Freshwater snails from irrigation canals(abueshreens)were sampled monthly from January 2004 to December *** snails were examined for trematode infections by cercarial emergence immediately after collection and then weekly for an additional four weeks to allow for the maturation of prepatent *** cover in the study sites as well as the physicochemical characteristics of the water,including temperature,were also ***:A total of 10,493 snails,representing seven species,were *** most abundant species was Biomphalaria pfeifferi,representing 48.6%of the ***,14.1%of the snails were found to be shedding some type of *** species were found to have infections;among these the Bulinus truncatus species was found to be the most heavily infected,with an overall prevalence of 46.2%.Double infections were recorded in only two *** snails and one Cleopatra bulimoides *** different morphotypes of cercariae were recorded,seven of which appeared not to conform to previously described cercariae from *** type 1 was the most common type of cercariae recovered,accounting for 44.3% of all *** density of snails tended to be lower during the summer months than the winter months,except for *** snails,which were not affected by seasonal ***:The findings of this study indicate that besides sc

关键词： Freshwater snails Trematode cercariae Biomphalaria Bulinus East Nile locality Khartoum Sudan

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An Efficient Indoor Localization Based on Deep Attention Learning Model

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Computer Systems Science & Engineering 2023年第8期46卷 2637-2650页

作者： Amr Abozeid ahmed I.Taloba rasha M.Abd El-aziz Alhanoof Faiz Alwaghid Mostafa Salem ahmed Elhadad Department of Computer Science College of Science and ArtsJouf UniversityQurayyatSaudi Arabia Information System Department Faculty of Computers and InformationAssiut UniversityEgypt Computer Science Department Faculty of Computers and InformationAssiut UniversityAssiutEgypt Department of Computer Science Faculty of Computers and InformationSouth Valley UniversityQenaEgypt

Indoor localization methods can help many sectors,such as healthcare centers,smart homes,museums,warehouses,and retail malls,improve their service *** a result,it is crucial to look for low-cost methods that can provide exact localization in indoor *** this context,imagebased localization methods can play an important role in estimating both the position and the orientation of cameras regarding an ***-based localization faces many issues,such as image scale and rotation ***,image-based localization’s accuracy and speed(latency)are two critical *** paper proposes an efficient 6-DoF deep-learning model for image-based *** model incorporates the channel attention module and the Scale PyramidModule(SPM).It not only enhances accuracy but also ensures the model’s real-time *** complex scenes,a channel attention module is employed to distinguish between the textures of the foregrounds and *** model adapted an SPM,a feature pyramid module for dealing with image scale and rotation variance ***,the proposed model employs two regressions(two fully connected layers),one for position and the other for orientation,which increases outcome *** on standard indoor and outdoor datasets show that the proposed model has a significantly lower Mean Squared Error(MSE)for both position and *** the indoor 7-Scenes dataset,the MSE for the position is reduced to 0.19 m and 6.25°for the ***,on the outdoor Cambridge landmarks dataset,the MSE for the position is reduced to 0.63 m and 2.03°for the *** to the findings,the proposed approach is superior and more successful than the baseline methods.

关键词： Image-based localization computer vision deep learning attention module VGG-16

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Investigation on the mechanical properties of sintered porous copper compacts

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China Particuology 2007年第6期5卷 391-394页

作者： Yasser M.Z. ahmed Mohamed I. Riad ahmed I. Zaky Mohammed abdel-aziz Mohamed M.H. Shalabi Central Metallurgical Research and Development Institute CMRDI El-Felzat Street El-Tabbin P.O. Box 87 Helwan Cairo Egypt

In line with recent attention on porous metals having low and medium porosities in the range of 20-50%, this paper studies the effect of porosity on the mechanical properties of sintered copper compacts. Experiments were designed to investigate the effect of porosity, applied stress and sliding velocity on the wear rate of copper compacts, leading to the finding that the effects of both porosity and applied stress of the wear test on the wear rate are approximately similar and higher than that of sliding velocity. The investigation concerning the effect of porosity on compressive strength indicated that the stress-strain curve of high-porosity compact exhibited identifiable ultimate strength points, though low-porosity compact showed distinct stages of elastic plastic behavior.

关键词： Porous copper Wear rate Compressive strength Experimental design technique

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Intestinal protozoa and intestinal helminthic infections among schoolchildren in Central Sudan

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Asian Pacific Journal of Tropical Medicine 2010年第4期3卷 292-293页

作者： abdel-aziz M.ahmed Azam A.Afifi Elfatih M.Malik Ishag Adam University of Khartoum Sudan Preventive Medicine Federal Ministry of HealthSudan

Objective:To determine the prevalence of intestinal parasitic infections and soil-transmitted helminths(STHs) among primary schoolchildren in El dhayga,Central ***:In this cross-sectional study,three fresh faecal samples were collected from each child,which were examined by direct wet mount,brine flotation,formalin-ether and Kato-Katz *** intensity of each STH infection was expressed as the mean of eggs per gram counts of the three ***:In total,142(90.4%) of 157 children harboured at least one type of intestinal *** lumbricoides,Hymenolepis nana,Entamoeba histolytica and Giardia lamblia were the most common parasites found,with prevalence rates of 32.5%,30.6%,33.1%and 19.7%,*** of these 157 children,29(18.5%) harboured more than two intestinal parasitic *** cases of Schistosoma mansoni or Enterobius vermicularis were identified. Conclusions:The study demonstrates significant burden of intestinal protozoa and STH infections in this part of Sudan and highlights the need for preventive and intervention measures.

关键词： Schoolchildern Helminthes Intestinal Protozoa Sudan

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