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Journal of Acute Disease 2021年第3期10卷 107-111页

作者： HebatAllah Fadel Algebaly Ahmed Abd-elal rasha el kaffas elshymaa Salah Ahmed Pediatric Critical Care Department Cairo University School of MedicineEgypt Department of Clinical and Chemical Pathology Cairo University School of MedicineEgypt

Objectives:To determine the predictive value of lactate dehydrogenase(LDH)in the diagnosis of septic shock and its association with other prognostic scores in critical pediatric ***:A cross-sectional study was performed at Children’s Hospital of Cairo University between June 2019 and December 2019.A total of 200 pediatric patients were divided into the septic shock group[100 critically ill patients with septic shock from the pediatric intensive care unit(PICU)]and the control group(100 patients with only sepsis).LDH was determined in the first 24 hours of *** sensitivity and specificity of LDH in diagnosis of septic shock were assessed;the levels of related indicators of patients with different etiologies were compared;correlations between LDH,Paediatric Index of MortalityⅡ,and Pediatric Sequential Organ Failure Assessment(pSOFA)were ***:Median LDH was 512μL(406.50-663.00)in the septic shock group and was significantly higher than that[190μL(160.00-264.50)]in the control group(Pelation was found between pSOFA and LDH(r=0.503,P<0.001).Conclusions:LDH could be a potential inflammatory marker in the diagnosis of septic shock and is valuable for PICU admission decisions.

关键词： Lactate dehydrogenase Septic shock pSOFA

Smart homes: potentials and challenges

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Clean Energy 2021年第2期5卷 302-315页

作者： rasha el-Azab electrical Power and Machines Department Faculty of Engineering at Helwan UniversityCairoEgypt

Decentralized distributed clean-energy sources have become an essential need for smart grids to reduce the harmful effects of conventional power *** homes with a suitable sizing process and proper energy-management schemes can share in reducing the whole grid demand and even sell clean energy to the *** homes have been introduced recently as an alternative solution to classical power-system problems,such as the emissions of thermal plants and blackout hazards due to bulk plants/transmission *** appliances,sources and energy storage of smart homes should be coordinated with the requirements of homeowners via a suitable energy-management ***-management systems are the main key to optimizing both home sources and the operation of loads to maximize home-economic benefits while keeping a comfortable *** intermittent uncertain nature of smart homes may badly affect the whole grid *** prospective high penetration of smart homes on a smart power grid will introduce new,unusual scenarios in both generation and *** this paper,the main features and requirements of smart homes are *** review aims also to address recent proposed smart-home energy-management ***,smart-grid challenges with a high penetration of smart-home power are discussed.

关键词： smart homes energy-management system electrical tariff smart-home infrastructure load scheduling power-quality control

Selenoprotein-p and insulin resistance in children and adolescents with obesity

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World Journal of Clinical Pediatrics 2024年第3期13卷 40-52页

作者： Amany elbarky Kholoud Gamal Ismail Yousef Fouad Yousef rasha Mohamed Gamal elshafiey Radwa Mahmoud elsharaby Asmaa el-kaffas Mohammed Al-Beltagi Gastroenterology and Clinical Nutrition Unit Pediatric DepartmentFaculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Clinical Pathology Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Paediatric University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671ManamaBahrain

BACKGROUND Insulin resistance and obesity present significant challenges in pediatric *** P1(SEPP1)serves as a biomarker for assessing selenium levels in the *** its association with metabolic syndrome is established in adults,its relevance in children remains *** To ascertain SEPP1 blood levels in children and adolescents diagnosed with obesity and to assess its correlation with insulin resistance and adiposity *** 170 children participated in this study,including 85 diagnosed with obesity and an equal number of healthy counterparts matched for age and *** participant underwent a comprehensive medical evaluation,encompassing a detailed medical history,clinical examination,and anthropometric measurements like waist circumference and waist-to-height ***,routine blood tests were conducted,including serum SEPP1,visceral adiposity index(VAI),and Homeostatic Model Assessment of Insulin Resistance(HOMA-IR)*** Our findings revealed significantly lower serum SEPP1 levels in children with obesity compared to their healthy ***,notable negative correlations were observed between serum SEPP1 levels and body mass index,VAI,and *** The study suggests that SEPP1 could serve as a valuable predictor for insulin resistance among children and adolescents diagnosed with *** highlights the potential utility of SEPP1 in pediatric metabolic health assessment and warrants further investigation.

关键词： Obesity Childhood obesity Selenium status Selenoprotien P1 Insulin resistance

Arrhythmia Detection by Using Chaos Theory with Machine Learning Algorithms

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Computers, Materials & Continua 2024年第6期79卷 3855-3875页

作者： Maie Aboghazalah Passent el-kafrawy Abdelmoty M.Ahmed rasha elnemr Belgacem Bouallegue Ayman el-sayed Math and Computer Science Department Faculty of ScienceMenoufia UniversityShebin El-komEgypt College of Engineering Computer Science DepartmentEffat UniversityJeddahKingdom of Saudi Arabia Department of Computer Engineering College of Computer ScienceKing Khalid UniversityAbha61421Saudi Arabia Computer Science and Engineering Department Faculty of Electronic EngineeringMenoufia UniversityShebin El-komEgypt Climate Change Information Center and Expert Systems Agriculture Research CenterGizaEgypt

Heart monitoring improves life ***(ECGs or EKGs)detect heart *** learning algorithms can create a few ECG diagnosis processing *** first method uses raw ECG and time-series *** second method classifies the ECG by patient *** third technique translates ECG impulses into Q waves,R waves and S waves(QRS)features using richer *** ECG signals vary naturally between humans and activities,we will combine the three feature selection methods to improve classification accuracy and *** using all three approaches have not been examined till *** researchers found that Machine Learning(ML)techniques can improve ECG *** study will compare popular machine learning techniques to evaluate ECG *** algorithms—Support Vector Machine(SVM),Decision Tree,Naive Bayes,and Neural Network—compare categorization *** plus prior knowledge has the highest accuracy(99%)of the four ML *** characteristics failed to identify signals without chaos *** 99.8%classification accuracy,the Decision Tree technique outperformed all previous experiments.

关键词： ECG extraction ECG leads time series prior knowledge and arrhythmia chaos theory QRS complex analysis machine learning ECG classification

Prophylactic effect of vitamin E against hepatotoxicity,nephrotoxicity,haematological indices and histopathology induced by diazinon insecticide in mice

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Current Zoology 2009年第3期55卷 219-226页

作者： Nahla S.el-SHENAWY rasha A.AL-EISA Fawzia el-SALMY Omema SALAH Biology Department Faculty of ScienceTaif UniversityKingdom of Saudi Arabia

Considering that the involvement of reactive oxygen species （ROS） has been implicated in the toxicity of various pesticides, this study was designed to study the ameliorative effect of Vitamin E （100 mg/kg body weight） on mice （25 -30 mg） treated with diazinon （32.5 or 16.25 mg/kg body weight） organophosphate insecticide for 14 days. Subehronic DZN exposure and the protective effects of vitamins E （vitE） were evaluated for their effects on haematological indices, the enzymes concerning liver damage [plasma alanine aminotransferase （ ALT）, aspartate aminotaransferase （ AST）, alkaline phosphatise （ ALP）, and some parameters of kidney function （urea and creatinine） in mice. Additionally, the histopathological changes in liver and kidney tissue were examined. The high dose of diazinon （DZNH） decreased the body weight significantly at the end of experiment. Additionally, the liver and kidney were examines for histopathological changes. The high dose of diazinon decreased body weight significandy. Moreover, there was a statistically significant decrease in haemoglobin （Hb）, red blood cell （RBC） and hematocrit （Hct） in diazinon-treated mice compared to controls. This decrease was partially remedied in the diazinon-treated group that also received vitE. Damage in the liver and kidney tissues was also evident as elevated plasma ALT, AST, ALP, urea and creatinine. VitE partially counteracts the toxic effect of DZN and repairs tissue damage in the liver and kidney, especially when supplemented to 1/4 LD50 intoxicated animals. Histopathological changes in liver and kidney were observed only in 32.5 mg/kg DZN given group. These results suggest that the effects of DZN are dose dependent. No pathological findings were observed in vitE ＋ DZNtreated groups. According to the present study, we conclude that vitE ean reduce the detrimental impacts of diazinon on haematological indicies, as well as liver and kidney function [ Current Zoology 55 （3）： 219 - 226, 2009].

关键词： Organophosphorus insecticide Alanine aminotransferase (ALT) Aspartate aminotransferase (AST) Albumin Urea Creatinine Histopathology

Enhancing Task Assignment in Crowdsensing Systems Based on Sensing Intervals and Location

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Computers, Materials & Continua 2022年第6期71卷 5619-5638页

作者： rasha Sleem Nagham Mekky Shaker el-Sappagh Louai Alarabi Noha AHikal Mohammed elmogy Faculty of Computers and Information Mansoura UniversityMansoura35516Egypt Faculty of Computers and Artificial Intelligence Benha UniversityBanha13518Egypt Faculty of Computer Science and Engineering Galala UniversitySuez435611Egypt College of Computer and Information Systems Umm Al-Qura UniversityMecca715Saudi Arabia

The popularity of mobile devices with sensors is captivating the attention of researchers to modern techniques,such as the internet of things(IoT)and mobile crowdsensing(MCS).The core concept behind MCS is to use the power of mobile sensors to accomplish a difficult task collaboratively,with each mobile user completing much simpler *** paper discusses the task assignment problem in mobile crowdsensing,which is dependent on sensing time and path planning with the constraints of participant travel distance budgets and sensing time *** goal is to minimize aggregate sensing time for mobile users,which reduces energy consumption to encourage more participants to engage in sensing activities and maximize total task *** paper introduces a two-phase task assignment framework called location time-based algorithm(LTBA).LTBA is a framework that enhances task assignment in MCS,whereas assigning tasks requires overlapping time intervals between tasks and mobile users’tasks and the location of tasks and mobile users’*** process of assigning the nearest task to the mobile user’s current path depends on the ant colony optimization algorithm(ACO)and Euclidean *** combines two algorithms:(1)greedy online allocation algorithm and(2)bio-inspired traveldistance-balance-based algorithm(B-DBA).The greedy algorithm was sensing time interval-based and worked on reducing the overall sensing time of the mobile user.B-DBA was location-based and worked on maximizing total task *** results demonstrate that the average task quality is 0.8158,0.7093,and 0.7733 for LTBA,B-DBA,and greedy,*** sensing time was reduced to 644,1782,and 685 time units for LTBA,B-DBA,and greedy,*** the algorithms improves task assignment in MCS for both total task quality and sensing *** results demonstrate that combining the two algorithms in LTBA is the best performance for total task quality and total sensing time,and the greed

关键词： Mobile crowdsensing online task assignment participatory sensing path planning sensing time intervals ant colony optimization

Conventional generation emulation for power grids with a high penetration of wind power

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Clean Energy 2021年第1期5卷 93-103页

作者： rasha el-Azab Eslam M.Wazeer Mohamed Daowd A.M.Abdel Ghany electrical Power and Machines Department Faculty of EngineeringHelwan UniversityCairoEgypt

Integrating large-scale wind plants with the electricity grids has many challenges for grid *** the variability and uncertainty of wind power,coordinating between different technologies of generation in the same grid can be considered the main problem,specifically for short-term frequency ***,a large penetration of wind power generation in modern power grids has a risky influence on the power-system ***-generation plants have contradictory behaviour compared to classic thermal plants,especially in active generated power-shortage events due to the variable nature of wind *** experience in wind plants keeps part of the available wind power unloaded,using what are known as deloading *** deloading techniques are usually applied to emulate the thermal-plant-governor function and confirm a proper spinning reserve for any active-power *** techniques decrease the generated power from wind plants continuously from maximum point tracking ***,the practical capacity,annual generated energy and economical income of wind plants are *** addition,grid-protection and control sub-schemes are set and designed according to the well-known conventional responses of thermal plants,which increase the need for thermal-plant-behaviour *** this paper,instead of the usual deloading methods,a supercapacitors scheme is proposed with wind turbines to emulate the response of conventional power *** study discusses the technical and economic benefits of the proposed addition of supercapacitors in the wind-plant-planning *** frequency grid-code indices are selected to evaluate studied *** results of the IEEE four-generation two-area system determines the effectiveness of suggested schemes *** System Advisor Model(SAM)program estimates the economic benefits of a typical US study case compared with the existing wind-deloading technique.

关键词： wind energy planning analysis energy storage supercapacitor frequency stability

Evaluation of GALAD Score in Diagnosis and Follow-up of Hepatocellular Carcinoma after Local Ablative Therapy

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Journal of Clinical and Translational Hepatology 2023年第2期11卷 334-340页

作者： rasha eletreby Marwa elsharkawy Alaa Awad Taha Mohamed Hassany Amr Abdelazeem Mohamed el-Kassas Ahmed Soliman Endemic Medicine Department Faculty of MedicineCairo UniversityCairoEgypt Clinical and Chemical Pathology Department Faculty of MedicineCairo UniversityCairoEgypt Hepatogastroenterology Department Theodore Bilharz Research InstituteGizaEgypt Hepatogastroenterology Department National Hepatology and Tropical Medicine Research InstituteCairoEgypt Endemic Medicine Department Faculty of MedicineHelwan UniversityCairoEgypt

Background and Aims:Strategies for detection of early hepatocellular carcinoma(HCC)are still *** GALAD score is a serum biomarker-based model designed to predict the probability of having *** aimed to assess the ability of GALAD score to diagnose early HCC and its validity to follow patients after local ablation ***:This multicenter prospective study included 108 patients in two groups,58 HCC patients(67 focal lesions)with local ablative therapy(study group),and a control group of 50 patients with liver *** GALAD scores of the study and control groups,and of the HCC patients before and after ablative therapy were ***:Most patients were men(74.1%in study group and 76%in controls)with hepatitis C virus infection(98.30%in the study group,and 94%in controls).GALAD scores were significantly higher in HCC patients than in those with benign cirrhosis(2.65 vs.−0.37,p=0.001).Ablative therapy was successful in 94.4%of focal lesionsell-ablated tumors(2.19 vs.0.98,p=0.001).The best cutoff values of GALAD score for diagnosis of early HCC,and for prediction of well ablation of HCC were 0.74 and≤3.31(areas under the curve of 0.92 and 0.75,sensitivities of 84.48%and 76.19%,specificities of 89.13%and 83.33%,positive predictive values of 90.74%and 94.1%,and negative predictive values of 82%and 35.7%respectively).Conclusion:The GALAD score was effective for the diagnosis of early HCC and for followup after ablative therapy.

关键词： GALAD score HCC Ablative therapy Liver cirrhosis Egypt

Comparative metabolomics of the different fractions of two saltwort(Salsola L.)species in relation to their anti-inflammatory activity

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Food Bioscience 2023年第1期51卷 937-949页

作者： Dina A.Selim Eman Shawky Doaa A.Ghareeb Shaymaa A.Abdulmalek rasha M.Abu el-Khair Department of Pharmacognosy Faculty of PharmacyAlexandria UniversityEgypt Bio-screening and Preclinical Trial Lab Biochemistry DepartmentFaculty of ScienceAlexandria UniversityAlexandriaEgypt Biochemistry Department Faculty of ScienceAlexandria UniversityAlexandriaEgypt Center of Excellence for Drug Preclinical Studies(CE-DPS) Pharmaceutical and Fermentation Industry Development CenterCity of Scientific Research&Technological Applications New Borg El ArabAlexandriaEgypt College of PharmacyArab Academy for ScienceTechnology and Maritime TransportAlexandriaEgypt

Many of the plants of genus Salsola are edible halophytes which are known for their use in treatment of inflammation as well as their nutritional *** study aims at comprehensive chemical profiling of two Salsola species that are widely distributed in arid areas;*** and ***,using UHPLC-QqQ-MS in an attempt to decipher the bioactive constituents of the aerial parts of the selected plants and their ex-vivo antiinflammatory activity.73 chromatographic peaks were annotated where phytosterols dominated the metabolites in *** while phenylalkylamines were the major constituents detected in ***-DA model coefficients plot indicated that tetradecanoic acid,beta sitosterol and pentacosane were positively correlated to discrimination of *** species while N-feruloyloctopamine,N-feruloyltyramine,and ferulic acid,were positively correlated to discrimination of *** ***,fractions of ***,reduced the 5 upregulation of TNF-αcaused by LPS to levels lower than those produced by piroxicam while the petroleum ether and n-butanol fraction of *** were more effective than piroxicam in reducing IL-6 gene *** coefficients plot depicted that methyl palmitate,aegicin,cleomiscoside,beta sitosterol and sitostanol possessed strong positive correlation to the down regulation of the pro-inflammatory marker TNF-α,IL-1βand IFN-γwhile only norepinephrine derivatives were the major metabolites that showed strong positive correlation to the inhibition of IL-6 pro-inflammatory *** results obtained may help to explain chemically,the potential anti-inflammatory effect of the various Salsola species fractions increasing the value of the Salsola species as a putative functional foods.

关键词： Salsola jordanicola Salsola imbricata Chemometrics Anti-inflammatory UPLC/MS/MS Metabolomics

electrochemical Detection of the Different Species of Levofloxacin Using PVC,Carbon Paste and Screen‑Printed electrodes:Effect of pH

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Journal of Analysis and Testing 2018年第2期2卷 175-183页

作者： Nour elDin T.Abdel Ghani Fatehy M.Abdel‑Haleem Sonia Mahmoud rasha M.el Nashar Chemistry Department Faculty of ScienceCairo UniversityGizaEgypt

The zwitterionic compound,levofloxacin,was determined for the first time at different pH values in pure samples,pharmaceutical preparations and spiked serum and urine *** types of potentiometric sensors including poly(vinyl chloride)membrane electrode,carbon paste electrode and screen printed electrode,containing the ion pair levofloxaciniumphosphomolybdate as the electroactaive species,were used for this *** effect of pH is the key factor in determining the ratio of the different species that can exist in the medium(zwitterionic,monocationic,dicationic,anionic and neutral),and so it is the controller of the electrochemical *** different sensors were fully characterized and optimized in terms of composition,pH effect,selectivity,response and *** different sensors showed reliable reversibility and could be utilized for the determination of the drug in real spiked physiological fluids with reliable recovery values.

关键词： Levofloxacin Zwitterionic Poly(vinyl-chloride)(PVC)membrane electrode Carbon paste electrode(CPE) Screen-printed electrode(SPE)