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Acellular Mineralized Exoskeleton Shrimp (MES): A Natural Source of Bioactive Factors for Tissue Regeneration—Preliminary Results

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Journal of Biosciences and Medicines 2022年第3期10卷 34-43页

作者： raquel zita gomes Rodrigo Valdoleiros e Silva Américo Afonso Maria Helena Fernandes Mário Vasconcelos José Cavalheiro Faculty of Dental Medicine University of Porto Porto Portugal Private Practice (raquel zita Dental Clinic) Porto Portugal i3S—Institute for Research and Innovation in Health University of Porto Porto Portugal INEB—National Institute of Biomedical Engineering Porto Portugal ICBAS—Institute of Biomedical Sciences Abel Salazar University of Porto Porto Portugal School of Medicine University of Minho Braga Portugal Department of Histology Faculty of Dental Medicine University of Oporto Porto Portugal Department of Pharmacology Faculty of Dental Medicine University of Oporto Porto Portugal Department of Biomaterials Faculty of Dental Medicine University of Oporto Porto Portugal Faculty of Engineering University of Oporto Porto Portugal

Current challenges in the development of scaffolds for bone regeneration include the engineering of biomaterials that can withstand a natural dynamic physiology on the bone that provides a matrix capable of supporting cell migration and tissue ingrowth. The objective of the present work was to develop and characterize a new biomembrane—Mineralized Exoskeleton Shrimp (MES) developed from the exoskeleton of paleomonetes. The integration of MES as a biomaterial for tissue regeneration relies on the growing evidence that the shrimp is characterized by a hierarchically arranged chitin fiber structure, mineralized predominately by calcium carbonate and/or calcium phosphate, bringing beneficial effects in bone regeneration. Additionally, the tridimensional MES structure, can act as a “tent” for Guided Bone Regeneration (GBR). Recently, our team has characterized the MES biomaterial by in vitro (human osteoblastic cellular cultures and immersion of the membrane in modified synthetic plasma) and in vivo (soft tissue in lab mice and hard tissue in rabbit model). The cellular growth in the MES membrane was very exuberant in cellular culture with osteoblastic colonization on its surface (histophilic and biocompatible). After the immersion in modified synthetic plasma for one week, a mass mineralization occurred throughout the membrane’s surface (bioactive). The analysis of histological samples from experimental surgery in lab mice showed that the MES membrane wasn’t toxic to soft tissues and that it caused a moderate inflammatory response (first reabsorption signs at 8 weeks). The MES could act as a cell-guiding template that contains the necessary cues and adequate three-dimensional set to facilitate cell adhesion and promote tissue regeneration upon implantation and subsequent biodegradation.

关键词： Guided Bone Regeneration Biomaterial Biocompatibility Oral Surgery

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BIM Improved with RV and AR Technologies

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Journal of Software Engineering and Applications 2024年第6期17卷 508-521页

作者： Alcínia zita Sampaio raquel S. Sarmento Augusto M. gomes Department of Civil Engineering University of Lisbon Lisbon Portugal CERISCivil Engineering Research and Innovation for Sustainability IST University of Lisbon Lisbon Portugal

The study addresses the integration of the Building Information Modelling (BIM) methodology with Virtual Reality (VR) and Augmented Reality (AR) technologies in the context of the development of a multidisciplinary project, involving architecture, structures, water network and electrical system components. In order to cover in detail the various design features, the case study was limited to a specific area of a house, the sanitary rooms, as it presents sufficient complexity in modeling and the application of VR and AR software. The VR/AR functionalities applied over the BIM model increase the potential of BIM in the construction sector, contributing to the achievement of a high level of collaboration and control of the project based on an immersive and interactive environment. The elaboration of the different phases of a BIM design requires the transfer of models between BIM and VR/AR systems, allowing us to analyze the main advantages that BIM/VR/AR integration can introduce in the construction industry. The study contributes positively to achieving new knowledge in BIM, being disseminated in an academic research work and illustrated in a practical context.

关键词： BIM Multi-Disciplines Modeling Virtual Reality Augmented Reality Integration BIM/VR/AR Collaboration

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Professional One-Day Training Course in BIM: A Practice Overview of Multi-Applicability in Construction

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Journal of Software Engineering and Applications 2022年第5期15卷 131-149页

作者： Alcínia zita Sampaio Augusto M. gomes Department of Civil Engineering University of Lisbon Lisbon Portugal

The implementation of Building Information modelling (BIM) methodology in the construction industry has been covering wide applicability with recognized benefits in designing, constructing and operating buildings. A recent short course organized in the University of Lisbon, actualized with the most relevant achievement based in master research, was offered to professionals of the industry, namely, architects and civil engineers coming from diverse engineering areas, environment, construction, maintenance, consult and patrimonial enterprises and also from public organizations like city councils. The proposed action covers the areas of construction (conflict analysis, planning and materials take-off), structures (interoperability, analyses and transfer of information between software) and the most recent Heritage Building Information Modelling (HBIM) topic. The course aims to contribute to the dissemination of the potential of BIM in the areas of designing, construction and refurbishing of historical buildings. The participants followed the course with great interest and satisfaction, formulating several questions directed to the particular activity of each of the attendees.

关键词： BIM Training Course Up-to-Date Information Improve Professional Skills

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Multi-Project in an Integrated BIM Model: Clash Detection and Construction Planning

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Journal of Software Engineering and Applications 2022年第10期15卷 345-358页

作者： Alcínia zita Sampaio Nuno R. gomes Augusto M. gomes Alberto Sanchez-Lite Department of Civil Engineering University of Lisbon Lisbon Portugal CERIS—Civil Engineering Research and Innovation for Sustainability IST Lisbon Portugal Department of Mechanical Engineering School of Industrial Engineering Universidad de Valladolid Valladolid Spain

The Building Information Modelling (BIM) methodology has been adopted in the construction industry, supporting the development of projects. Its implementation has improved the collaboration and integration in the design context, increasing the accuracy of the project preparation and the decreasing additional costs and delays of the construction work. The main objective of the present research is to provide an overview of the state of the art of BIM applications, namely, concerning the construction planning. For that, the generation of a BIM 3D model, involving the disciplines of architecture, structures and water supply system was performed. After, over the model a conflict analysis was applied, in order to verify the consistency of all the disciplines, when linked together. In order to obtain a visual simulation of the construction process, the correspondent 4D BIM model was also generated. Along the development of the study, distinct BIM software was applied over a case study. The main remarks of the capacities of the software, as well as the benefits and limitations verified were identified.

关键词： BIM Planning Construction Conflict Analysis 4D Model Visual Simulation

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BIM Supporting the Development of Multitasks Related with the Structural Project

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Journal of Software Engineering and Applications 2023年第8期16卷 397-419页

作者： Alcínia zita Sampaio Augusto Martins gomes Paulo Manuel Sequeira Gonçalo Ferreira Azevedo Department of Civil Engineering University of Lisbon Lisbon Portugal CERIS—Civil Engineering Research and Innovation for Sustainability Lisbon Portugal

Building Information Modelling (BIM) is a methodology focused on the centralization and sharing of the project information among all professionals involved, supported on the generation and manipulation of a three-dimensional (3D) digital BIM model. This methodology allows a close collaboration between the architect and the structural engineer and an adequate manipulation of the structural BIM model database, on the definition of multitasks. The collaboration allowed between all disciplines, avoid the detection of conflicts and data omission after in the construction place. Two BIM structural design cases were developed, using Revit as the modelling system and Robot as the structural software. Concerning the structural project the interoperability capacity between the software is still a limitation that engineers must be warned of. In the present study, the benefits and limitations identified within the communication and integration of distinct disciplines and on the development of most frequent multitasks normally related with a structural project, were considered.

关键词： BIM Structural Project Communication Integration Interoperability Multitasks

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BIM Methodology Applied in Structural Design: Analysis of Interoperability in ArchiCAD/ETABS Process

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Journal of Software Engineering and Applications 2021年第6期14卷 189-206页

作者： Alcínia zita Sampaio Augusto M. gomes Tomas Farinha Department of Civil Engineering University of Lisbon Lisbon Portugal

The Building Information Modeling (BIM) methodology considers the representation of the building as a virtual BIM model and its main concept is to centralize all the information generated throughout the development of the project. Structural design involves a set of tasks, namely, structure definition, structural analyses, and after the generation of drawings and technical documentation. In all processes, it is required confidence in data transferred between the BIM systems used, and to support this, a high level of interoperability is claimed. The present study aims to evaluate the degree of interoperability between the BIM-based platforms, ArchiCAD (Graphisoft), Revit (Autodesk), and ETABS (CSI). Two-way data flows between these systems were explored using distinct transfer strategies: add-in applications;Industry Foundation Classes (IFC) standard data format. The research made allows identifying the most appropriate procedure to be adopted by structural engineers, given the interoperability limitations verified, enabling the establishment of a practical guide of sequential procedures on the development of structural designs using BIM tools.

关键词： Structural Design BIM Methodology Interoperability BIM Tools

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Interactive Model Used in Maintenance Planning of Facades Based on Virtual Reality Technology

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Journal of Civil Engineering and Architecture 2012年第10期6卷 1292-1309页

作者： Alcinia zita Sampaio Augusto M. gomes Ana Rita gomes Department of Civil Engineering and Architecture Technical University of Lisbon Lisbon 1049-001 Portugal

A virtual reality model was created in order to help in the maintenance of exterior closures and interior finishes of walls in a building. It allows the visual and interactive transmission of information related to the physical behavior of the elements, defined as a function of the time variable. To this end, the basic knowledge of material most often used in walls, anomaly surveillance, techniques of rehabilitation, and inspection planning were studied. This information was included in a database that supports the periodic inspection needed in a program of preventive maintenance. The results are obtained interactively and visualized in the virtual environment itself. This work brings an innovative contribution to the field of maintenance supported by emergent technology.

关键词：虚拟现实技术建筑物维护规划外墙动模虚拟现实模型预防性维护室内装饰

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