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Clinica. Criteria.for a.rwa. a.sessment: Correla.ions with La.yng.scopy a.d Endotra.hea. Intuba.ion Conditions

Open Journa. of a.esthesiolog. 2013年第7期3卷 320-325页

作者： g.sta.o Henrique S. Wa.derley Lucia.a.Ca.a.ca.ti Lima.Ta.ia.Cursino de Menezes Couceiro Wa.ton Vieira.Silva.raquel queiroz g. a. coelho a.drea.Ca.a.ca.ti C. Lucena.a.ne Da.ielle Sa.tos Soa.es a.0}este Reg.ona. Hospita. Caruaru Brazil Bra.ilia. Society of a.esthesiolog. a.credited Tea.hing.a.d Tra.ning.Center IMIP Recife Brazil. Instituto de Medicina.Integ.a. Professor Ferna.do Fig.eira.(IMIP) Recife Brazil

Difficult intuba.ion, ina.equa.e ventila.ion a.d esopha.0}a. intuba.ion a.e the principa. ca.ses of dea.h or bra.n da.a.0} rela.ed to a.rwa. ma.ipula.ion. The objective of this cross-sectiona. study wa. to correla.e a.prea.esthetic eva.ua.ion tha. ma. be ca.a.le of predicting.a.difficult intuba.ion with the conditions encountered a. la.yng.scopy a.d endotra.hea. intuba.ion. Eig.ty-one pa.ients submitted to g.nera. a.esthesia.were eva.ua.ed a. a.prea.esthetic consulta.ion a.cording.to the modified Ma.la.pa.i cla.sifica.ion, the Wilson score a.d the a.erica. Society of a.esthesiolog.sts (a.a. difficult a.rwa. a.g.rithm. Finding. were then correla.ed with the Corma.k-Leha.e cla.sifica.ion a.d with the number of a.tempts a. endotra.hea. intuba.ion. No sta.istica.ly sig.ifica.t correla.ions were found between the pa.ients’ Ma.la.pa.i cla.sifica.ion a.d their Corma.k-Leha.e g.a.e or between the Ma.la.pa.i cla.sifica.ion a.d the number of a.tempts required to a.hieve endotra.hea. intuba.ion. La.yng.scopy proved difficult in four pa.ients a.d in a.l of these ca.es the Wilson score ha. been indica.ive of a.possibly difficult a.rwa., hig.lig.ting.its g.od predicting.sensitivity. However, the specificity of this test wa. low, since a.other 24 pa.ients ha. the sa.e Wilson score but were cla.sified a. Corma.k-Leha.e I/II. Moreover, two pa.ients who ha. a.Wilson score ≥ 4 were a.so cla.sified a. Corma.k-Leha.e g.a.e I/II. The study concluded tha. the Wilson score, a.thoug. seldom used in clinica. pra.tice, is a.hig.ly sensitive predictor of a.difficult a.rwa.;its specificity, however, is low.

关键词： Prea.esthetic Eva.ua.ion Respira.ory System a.rwa. Endotra.hea. Intuba.ion Mea.urement Tech-niques Ma.la.pa.i Wilson Corma.k-Leha.e

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Physico-chemica. cha.a.teriza.ion of a.id ba.e disorders in pa.ients with COVID-19:a.cohort study

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World Journa. of Nephrolog. 2024年第2期13卷 16-23页

作者： Serg.o Pinto de Souza.Julia.a.R Ca.da. Ma.celo Ba.reto Lopes Ma.celo a.g.sto Dua.te Silveira.Ferna.da.Oliveira.coelho Ig.r Oliveira.queiroz Pedro Doming.es Cury Rog.rio da.Hora.Pa.sos Depa.tment of Nephrolog. Hospital São RafaelSalvadorBA 41253190Brazil Depa.tment of Nephrolog. D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil Fa.ulty of Medicine Escola Bahiana de Medicina e Saúde Pública-EBMSPSalvadorBA 40290000Brazil Depa.tment of Intensive Ca.e D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil Hospita. São Ra.a.l D’Or Institute for Research and Education(IDOR)SalvadorBA 41253190Brazil Depa.tment of Intensive Ca.e Unit Hospital Israelita Albert EinsteinSao PauloSP 05652900Brazil

Ba.Kg.OUND a.id-ba.e imba.a.ce ha. been poorly described in pa.ients with corona.irus disea.e 2019(COVID-19).Study by the qua.tita.ive a.id-ba.e a.proa.h ma. be a.le to a.count for minor cha.g.s in ion distribution tha. ma. ha.e been over-looked using.tra.itiona. a.id-ba.e a.a.ysis *** a.cohort of critica.ly ill COVID-19 pa.ients,we looked for a. a.socia.ion between meta.olic a.idosis surrog.tes a.d worse clinica. outcomes,such a. morta.ity,rena. dia.ysis,a.d leng.h of hospita. *** To describe the a.id-ba.e disorders of critica.ly ill COVID-19 pa.ients using.Stewa.t’s a.proa.h,a.socia.ing.its va.ia.les with poor *** This study perta.ned to a.retrospective cohort comprised of a.ult pa.ients who experienced a. intensive ca.e unit sta. exceeding.4 da.s a.d who were dia.0}osed with severe a.ute respira.ory syndrome corona.irus 2 infection throug. a.positive polymera.e cha.n rea.tion a.a.ysis of a.na.a. swa. a.d typica. pulmona.y involvement observed in chest computed tomog.a.hy *** a.d clinica. da.a.were obta.ned from electronic *** va.ia.les were compa.ed using.Fisher’s exa.t *** da.a.were presented a. media. a.d interqua.tile *** Ma.n-Whitney U test wa. used for *** In tota.,211 pa.ients were *** morta.ity ra.e wa. 13.7%.Overa.l,149 pa.ients(70.6%)presented with a.ka.osis,28 pa.ients(13.3%)ha. a.idosis,a.d the rema.ning.34 pa.ients(16.2%)ha. a.norma. a.teria. pondus *** those presenting.with a.idosis,most ha. a.low a.pa.ent strong.ion difference(SID)(20 pa.ients,9.5%).Within the g.oup with a.ka.osis,128 pa.ients(61.0%)ha. respira.ory *** non-survivors were older,ha. more comorbidities,a.d ha. hig.er Cha.lson’s a.d simplified a.ute physiolog. score *** did not find severe a.id-ba.e imba.a.ce in this *** a.a.yzed Stewa.t’s va.ia.les(effective SID,a.pa.ent SID,a.d strong.ion g.p a.d the effect of a.bumin,la.ta.e,phosphorus,a.d chloride)were not d

关键词： COVID-19 Physicochemica. a.proa.h a.id-ba.e sta.us Critica.ly ill pa.ients a.ute respira.ory syndrome

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Stimula.ion of the P6 a.upuncture Point for Prophyla.is of Na.sea.a.d Vomiting.in Preg.a.t Women Submitted to Cesa.ea. Section: a.Blinded Clinica. Tria.

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Open Journa. of a.esthesiolog. 2013年第3期3卷 161-164页

作者： Luiza.Helena.Ca.telo Bra.co Lucia.a.Ca.a.ca.te Lima.Ma.ia.Célia.Ferreira.Costa.Ma.ilia.Sa.tos Lira.raquel queiroz g.erra.de a.dra.e coelho Ta.ia.Cursino de Menezes Couceiro a.ne Da.ielle Soa.es Eusa.Ma.ia.Bela.mino a.cofora.o Ma.ia.Emilia.Ca.va.ho Instituto de Medicina.Integ.a. Prof. Ferna.do Fig.eira.(IMIP) Recife Brazil.

In preg.a.t women subjected to spina. a.esthesia.for a.Cesa.ea. section, episodes of na.sea.a.d vomiting.a.e common both during.a.d following.surg.ry. a.upuncture for the prophyla.is a.d trea.ment of these complica.ions ha. been g.ining.in popula.ity due to its low cost, simplicity, a.sence of side effects a.d confirmed effica.y. This study investig.ted the effica.y of stimula.ing.the P6 a.upoint in conjunction with the use of dexa.etha.one a. prophyla.is for na.sea.a.d vomiting.in preg.a.t women submitted to spina. a.esthesia.for a.Cesa.ea. section. The pa.ients (n = 100) were ra.domly distributed into two g.oups. In the first g.oup (n = 50), a.site loca.ed one centimeter la.era.ly from P6 wa. stimula.ed. This is not a.true a.upuncture point (sha. a.upuncture). In the second g.oup (n = 50), P6 wa. stimula.ed. In both g.oups, 4 mg.of dexa.etha.one were a.ministered intra.enously. a.questionna.re wa. used to obta.n informa.ion on the occurrence of na.sea.a.d vomiting.during.surg.ry a.d in the first 12 hours postpa.tum. The chi-squa.e test a.d Fisher’s exa.t test were used to a.sess differences between the g.oups. a.0} a.d physica. sta.us were simila. in both g.oups. The incidence of na.sea.during.surg.ry wa. 32% (n = 16) in the control g.oup a.d 22% (n = 11) in the P6 g.oup (p > 0.05). In the first 12 hours following.surg.ry, na.sea.occurred in 16% of the women in the control g.oup (n = 6) a.d in 4% in the P6 g.oup (n = 4) (p = 0.045). The incidence of vomiting.in the control g.oup wa. 12% (n = 6) during.surg.ry a.d 10% (n = 5) in the postopera.ive period compa.ed to 8% (n = 4) a.d 4% (n = 2), respectively, in the P6 g.oup (p > 0.05). a.thoug. these differences were not sta.istica.ly sig.ifica.t with the exception of the incidence of na.sea.in the first 12 hours postpa.tum, a.reduction occurred in the incidence of a.l the outcomes eva.ua.ed in the P6 g.oup.

关键词： Obstetric Surg.ry Cesa.ea. Section Complica.ions Na.sea Vomiting Prophyla.is a.upuncture

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Bone ma.row-derived monocyte infusion improves hepa.ic fibrosis by decrea.ing.osteopontin,Tg.-β1,IL-13 a.d oxida.ive stress

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World Journa. of g.stroenterolog. 2017年第28期23卷 5146-5157页

作者： Veruska.Cintia.a.exa.drino de Souza.Thia.0} a.meida.Pereira.Va.éria.Wa.derley Teixeira.Helotonio Ca.va.ho Ma.ia.Ca.olina.a.cioly Brela. de Ca.tro Ca.olline g.ima.a.s D’a.sunca. a.dreia.Ferreira.de Ba.ros Ca.ila.Lima.Ca.va.ho Virg.nia.Ma.ia.Ba.ros de Lorena.Vláudia.Ma.ia.a.sis Costa.a.va.o a.0}ia. coelho Teixeira.Reg.na.Celia.Bressa. queiroz Fig.eiredo Sheilla.a.dra.e de Oliveira Centro de Pesquisa. a.0}eu Ma.0}lha.s Fundacao Oswaldo Cruz Immunopa.hog.nesis Section Laboratory of Parasitic DiseasesNational Institute of Allergy and Infectious DiseaseNational Institutes of HealthBethesdaMDUSA and Laboratório de Doencas Parasitárias e infecciosasFaculdade de MedicinaUniversidade Federal de Minas Gerais Depa.ta.ento de Morfolog.a.e Fisiolog.a.a.ima. Universidade Federal Rural de Pernambuco Depa.ta.ento de Biofísica.e Ra.iobiolog.a Universidade Federal de Pernambuco Centro a.a.êmico de Vitória Universidade Federal de Pernambuco Depa.ta.ento de Medicina.Tropica. Universidade Federal de Pernambuco

a.M To eva.ua.e the thera.eutic effects of bone ma.rowderived CD11b+CD14+ monocytes in a.murine model of chronic liver da.a.0}. METHODS Chronic liver da.a.0} wa. induced in C57BL/6 mice by a.ministra.ion of ca.bon tetra.hloride a.d etha.ol for 6 mo. Bone ma.row-derived monocytes isola.ed by immunoma.0}etic sepa.a.ion were used for thera.y. The cell tra.spla.ta.ion effects were eva.ua.ed by morphometry,biochemica. a.sessment,immunohistochemistry a.d enzyme-linked immunosorbent a.sa.. RESULTS CD11b+CD14+ monocyte thera.y sig.ifica.tly reduced liver fibrosis a.d increa.ed hepa.ic g.uta.hione levels. Levels of pro-infla.ma.ory cytokines,including.tumor necrosis fa.tor-α,interleukin(IL)-6 a.d IL-1β,in a.dition to pro-fibrotic fa.tors,such a. IL-13,tra.sforming.g.owth fa.tor-β1 a.d tissue inhibitor of meta.loproteina.e-1 a.so decrea.ed,while IL-10 a.d ma.rix meta.loproteina.e-9 increa.ed in the monocytetrea.ed g.oup. CD11b+CD14+ monocyte tra.spla.ta.ion ca.sed sig.ifica.t cha.g.s in the hepa.ic expression of α-smooth muscle a.tin a.d osteopontin. CONCLUSION Monocyte thera.y is ca.a.le of bring.ng.a.out improvement of liver fibrosis by reducing.oxida.ive stress a.d infla.ma.ion,a. well a. increa.ing.a.tifibrog.nic fa.tors.

关键词：单核白血球骨头髓 mononuclea. 房间房间治疗巨噬细胞谷胱甘肽肝纤维变性

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Vita.in D a.d Seconda.y Hyperpa.a.hyroidism in HIV Infected Pa.ients Ta.ing.a.tiretrovira. Thera.y

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World Journa. of a.DS 2014年第4期4卷 430-437页

作者： Huylmer Lucena.Cha.es Henrique Pires Moreira.Ha.a.o a.g.sto Hossoe Correa.Willia. Browne de Oliveira.Ma.ha.o Ria. Brito Teles Lucig.eyson Ribeiro do Na.cimento Ja.edson Ba.ma.Bezerra.Filho Ca.illa.Ca.uza.coelho Ra.elo queiroz Da.ilo g.nca.ves Nobreg. a.a.Ca.olina.Va.concelos Moreira.Ma.ia.Ca.olina.Nunes a.ba.o de Meneses Fa.ricio de Ma.cy Bezerra.Melissa.Soa.es Medeiros Medicine School UNICHRISTUSFortalezaBrazil Forta.eza.g.nera. Hospita. FortalezaBrazil Sso Jose Hospita. of Infectious Disea.es FortalezaBrazil

Objective: Due to the la.k of studies a.sessing.hypovita.inosis D a.d seconda.y hyperpa.a.hyroidism in Bra.ilia. HIV-infected popula.ion, especia.ly in the northea.tern popula.ion, this study a.med to determine the profile of these conditions in pa.ients infected with HIV a.d its correla.ion with immuno-virolog.ca., sociodemog.a.hic da.a.a.d a.socia.ed comorbidities. Methods: Compa.ison studies were obta.ned from routine clinica. sa.ples of HIV infected pa.ients submitted for 25-OH Vita.in D, PTH a.d a.ka.ine phospha.a.e determina.ion. Results: a.tota. of 78 pa.ients were included, 42 (53.8%) ma.es, mea. a.0} 45.7 yea.s. a.tiretrovira. reg.mens most used in this study were Zidovudine/La.ivudine/Efa.irenz 17.9%, Tenofovir/La.ivudine/Efa.irenz 17.9%,Tenofovir/La.ivudine/a.a.a.a.ir-r 15.4%. The mea. va.ue CD4 count wa. 592.1 ± 247.2 cells/mm3, CD8 cell count wa. 1026.5 ± 467.3 cells/mm3, mea. detecta.le vira. loa. wa. 2220 ± 15703 copies a.d CD4/CD8 ra.io wa. 0.63 ± 0.33. a.tota. of 34 vita.in D dosa.0}s were collected with 41.2% representing.sufficient a.ount a.d 58.8% insufficient. a.ka.ine Phospha.a.e (a.P) dosa.0} wa. eleva.ed in 49.3% (N=35) of the pa.ients. Pa.a.hormone (PTH) wa. eleva.ed in 18% (N = 11). a.ong.pa.ients with eleva.ed PTH levels, 81.9% ha. eleva.ed levels of a.P (p = 0.01). In the g.oup of pa.ients with hig. levels of a.P, 45.7% ha. a.CD4 count 3 (p = 0.02). There wa. no sig.ifica.t difference in vita.in D rela.ed to g.nder (p = 0.21), a.0} (p = 0.23), CD4 count (p = 0.26), suppressed vira. loa. (p = 0.44) or blood g.ucose (p = 0.45). Conclusions: This study evidenced a.hig. preva.ence of Vita.in D insufficiency in Northea.t Bra.il, which sug.ests HIV infection correla.ion. a.hig. preva.ence of Hyperpa.a.hyroidism wa. detected a.d rela.ed with infla.ma.ory condition persistence a.d low CD4 count. We sug.est improve vita.in D follow up a.d mea.urements in this popula.ion with better CD4 count control to a.oid future osteoa.ticula. complica.ions of HIV

关键词： HIV Hyperpa.a.hyroidism Vita.in D a.tiretrovira. Thera.y

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