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Analysis of a passive ankle exoskeleton for reduction of metabolic costs during walking

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Defence Technology（防务技术） 2024年第7期37卷 62-68页

作者： Luís Quinto Pedro Pinheiro Sergio B.goncalves Ivo Roupa Paula Simoes Miguel Tavares da Silva CINAMIL Academia MilitarInstituto Universitario MilitarLisbonPortugal IDMEC Instituto Superior TecnicoUniversidade de LisboaLisbonPortugal

Modern conflicts demand substantial physical and psychological exertion,often resulting in fatigue and diminished combat or operational *** exoskeletons have been developed recently to address these challenges,presenting various limitations that affect their operational or everyday *** article evaluates the performance of a dual-purpose passive ankle exoskeleton developed for the reduction of metabolic costs during walking,seeking to identify a force element that could be applied to the target *** on the 6-min walk test,twenty-nine subjects participated in the study using three different force *** results indicate that it is possible to reduce metabolic expenditure while using the developed ***,the comfort and range of motion results verify the exoskeleton's suitability for use in uneven terrain and during extended ***,the choice of the force element should be tailored to each user,and the control system should be adjustable to optimise the exoskeleton's performance.

关键词： Ankle passive exoskeleton Metabolic cost reduction Dual-use exoskeleton Gait Biomechanics

Morphology and Thermal Properties of Core-Shell PVA/PLA Ultrafine Fibers Produced by Coaxial Electrospinning

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Materials Sciences and Applications 2015年第2期6卷 189-199页

作者： raquel P.goncalves Flavia F.F.da Silva Paulo H.S.Picciani Marcos L.Dias Institute of Macromolecules Federal University of Rio de JaneiroRio de JaneiroBrazil

Coaxial electrospinning process was used to produce biodegradable membranes made of coreshell fibers of a poly(lactic acid) (PLA) shell and a poly(vinyl alcohol) (PVA) core. Scanning electron microscopy analyses of these structures showed that the PLA shell can present certain porosity depending on the process condition. FTIR-ATR and contact angle measurements also suggested imprisonment of the PVA core within the PLA shell. This type of structure was also confirmed by means of transmissions electron microscopy. The morphology of these fibers was dependent on the flow rate of both core and shell solutions, and homogeneous and smooth surface was only attained when the flow rate of the external PLA solution was 4 times the flow rate of the internal PVA solution. The increase in the PLA solution flow rate increases the diameter of the core-shell fiber which reaches up to 1.7 μm. Nevertheless, fibers with smaller average diameter could also be produced (200 nm). These core-shell fibers presented improved hydrophilicity as compared with monolithic PLA fibers.

关键词： Core-Shell Fibers Electrospinning Poly(Lactic Acid) Poly(Vinyl Alcohol)

What is the effect of Tribulus terrestris on testicular morphology and sperm production?An experimental study in the rat model

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Asian Journal of Andrology 2024年第1期26卷 67-70页

作者： Marcello Henrique Araujo Da Silva Gabriela Faria Buys-goncalves Joao Henrique Duque Reis Estrada Francisco Jose Barcellos Sampaio Diogo Benchimol de Souza Urogenital Research Unit Rio de Janeiro State UniversityRio de Janeiro 20551-030RJBrazil

The objective of this study was to investigate whether treatment with Tribulus terrestris(Tt)has any impact on the testicular morphology and function in a rodent *** male rats were divided into a control group and a group receiving 100 mg kg^(-1) body weight of Tt *** 4o days of experiment,the animals were submitted to euthanasia;epididymal tail spermatozoa were collected;and spermatozoa concentration,motility,and viability were *** addition,testicles were collected and processed for histomorphometrical *** were compared using the Student's t-test and considered significant when P<*** concentration,motility,and viability showed no difference between the ***,testicular weight and volume,seminiferous tubule diameter,tunica propria surface density,seminiferous epithelium surface density,and intertubular compartment surface density were statistically similar between the ***,seminiferous epithelium height and tubular lumen surface density were augmented in animals treated with *** with Tt does not cause a major impact on testicular morphology,promoting only subtle *** difference on spermatozoa parameters was observed.

关键词： morphometry testicle Tribulus terrestris

Automatic detection of Acacia longifolia invasive species based on UAV-acquired aerial imagery

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Information Processing in Agriculture 2022年第2期9卷 276-287页

作者： Carolina goncalves Pedro Santana Tomas Brandao Magno Guedes ISCTE-Instituto Universitario de Lisboa Portugal Instituto de Telecomunicacoes LisboaPortugal Information Sciences and Technologies and Architecture Research Center(ISTAR-IUL) LisboaPortugal IntRoSys SA Portugal

The Acacia longifolia species is known for its rapid growth and dissemination,causing loss of biodiversity in the affected *** order to avoid the uncontrolled spread of this species,it is important to effectively monitor its distribution on the agroforestry *** this purpose,this paper proposes the use of Convolutional Neural Networks(CNN)for the detection of Acacia longifolia,from images acquired by an unmanned aerial *** models based on the same CNN architecture were *** classifies image patches into one of nine possible classes,which are later converted into a binary model;this model presented an accuracy of 98:6%and 98:5%in the validation and training sets,*** second model was trained directly for binary classification and showed an accuracy of 98:8%and 98:7%for the validation and test sets,*** results show that the use of multiple classes,useful to provide the aerial vehicle with richer semantic information regarding the environment,does not hamper the accuracy of Acacia longifolia detection in the classifier’s primary *** presented system also includes a method for increasing classification’s accuracy by consulting an expert to review the model’s predictions on an automatically selected sub-set of the samples.

关键词： Pattern recognition Convolutional neural networks Invasive plants Acacia longifolia

Structure of human NCC:insights into the inhibition mechanism of thiazides

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Signal Transduction and Targeted Therapy 2023年第8期8卷 3549-3550页

作者： Livia de Souza goncalves Pattareeya Yottasan Onur Cil Department of Pediatrics University of CaliforniaSan FranciscoSan FranciscoCAUSA

A recent study published in Nature by Fan et al.1 identified the structure of human NCC alone and in complex with a thiazide diuretic using cryo-electron *** extensive clinical use of NCC inhibitor thiazide diuretics since 1950s,the structure and inhibition mechanisms of NCC have remained elusive,and Fan et *** is a major step toward better understanding the NCC biology and mechanism of action of thiazide ***-chloride cotransporter(NCC,also known as SLC12A3)is expressed in the kidney where it facilitates electroneutral NaCl absorption.

关键词： azide mechanism

Extracts of the seaweed Bifurcaria bifurcata display antifungal activity against human dermatophyte fungi

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Journal of Oceanology and Limnology 2019年第3期37卷 848-854页

作者： CARVALHO G.Loic SILVA raquel goncalves J.Maria BATISTA T.Maria PEREIRA Leonel Environmental and Biochemical Sciences Group the James Hutton InstituteDundee DD2 5DAScotlandUK Institute of Mechanical Process and Energy EngineeringSchool of Engineering and Physical SciencesHeriot Watt UniversityEdinburgh EH14 4ASScotlandUK MARE (Marine and Environmental Sciences Centre) Department of Life SciencesFaculty of Sciences and TechnologyUniversity of CoimbraCoimbra 3030-790Portugal CIEPQPF Department of Chemical EngineeringFaculty of Science and TechnologyUniversity of CoimbraCoimbra 3030-790Portugal

Bifurcaria bifurcata is a seaweed of the Order Fucales(Ochrophyta,Phaeophyceae)that can be found all year round along the Portuguese Atlantic *** it is considered edible in some countries,its biotechnological potential has not yet been assessed in detail and here we report its antimicrobial potential against human dermatophyte *** samples were harvested from Baleal Island(Peniche,Portugal)harvested in winter(BbPe);from Aguda Beach(Arcozelo,Vila Nova de Gaia,Portugal),harvested in autumn(BbAg)and a sample obtained by culturing the Aguda sample under laboratory conditions(BbLC).A broth macrodilution assay was applied to determine the MIC(minimum inhibitory concentration)and MLC(minimum lethal concentration)of the *** *** show that the BbPe MeOH extracts were the most effective and had higher antifungal activity against all the tested dermatophyte strains than the BbLC and BaAg extracts[Epidermophyton floccosum FF9(100–200μg/mL MIC;200μg/mL MLC),Microsporum canis FF1(400μg/mL MIC;≥400μg/mL MLC),Trichophyton mentagrophytes FF7(100μg/mL MIC;>800μg/mL MLC),*** CECT 2908(800μg/mL MIC;≥800μg/mL MLC),*** *** CECT 2958(800μg/mL MIC;≥800μg/mL MLC),*** CECT 2794(200μg/mL MIC;≥400μg/mL MLC)].In fact,only *** FF9 was sensitive to BbAg and BbLC MeOH *** our knowledge,this is the first report of antifungal activity of *** against human dermatophyte fungi.

关键词： seaweed Bifurcaria bifurcata bioactivity antifungal dermatophytes minimum inhibitory concentration minimum lethal concentration

Free Cyclic Actions on Surfaces and the Borsuk-Ulam Theorem

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Acta Mathematica Sinica,English Series 2022年第10期38卷 1803-1822页

作者： Daciberg Lima goncalves John GUASCHI Vinicius Casteluber LAASS Departamento de Matematica IMEUniversidade de Sao PauloRua do Matao 1010 CEP:05508-090Sao Paulo-SPBrazil Normandie Univ. UNICAENCNRSLMNO14000 CaenFrance Universidade Federal da Bahia IMEDepartamento de MatematicaAv.Milton SantosS/N Ondina CEP:40170-110Salvador-BABrazil

Let M and N be topological spaces,let G be a group,and letτ:G×M→M be a proper free action of *** this paper,we define a Borsuk-Ulam-type property for homotopy classes of maps from M to N with respect to the pair(G,τ)that generalises the classical antipodal Borsuk-Ulam theorem of maps from the n-sphere S^(n) to R^(n).In the cases where M is a finite pathwise-connected CWcomplex,G is a finite,non-trivial Abelian group,τis a proper free cellular action,and N is either R^(2) or a compact surface without boundary different from S^(2) and RP^(2),we give an algebraic criterion involving braid groups to decide whether a free homotopy class β∈[M,N]has the Borsuk-Ulam *** an application of this criterion,we consider the case where M is a compact surface without boundary equipped with a free actionτof the finite cyclic group *** terms of the orient ability of the orbit space Mof M by the actionτ,the value of n modulo 4 and a certain algebraic condition involving the first homology group of M,we are able to determine if the single homotopy class of maps from M to R^(2) possesses the Borsuk-Ulam property with respect to(Z_(n),τ).Finally,we give some examples of surfaces on which the symmetric group acts,and for these cases,we obtain some partial results regarding the Borsuk-Ulam property for maps whose target is R^(2).

关键词： Borsuk-Ulam theorem cyclic groups braid groups surfaces

Enabling data-driven anomaly detection by design in cyber-physical production systems

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Cybersecurity 2022年第3期5卷 34-51页

作者： Rui Pinto Gil goncalves Jerker Delsing Eduardo Tovar Department of Informatics Engineering Faculty of EngineeringUniversity of PortoPortoPortugal EISLAB Lulea University of TechnologyLuleaSweden Research Centre in Real-Time and Embedded Computing Systems Polytechnic of Porto-School of EngineeringPortoPortugal

Designing and developing distributed cyber-physical production systems(CPPS)is a time-consuming,complex,and error-prone *** systems are typically heterogeneous,i.e.,they consist of multiple components implemented with different languages and development *** of the main problems nowadays in CPPS implementation is enabling security mechanisms by design while reducing the complexity and increasing the system’s *** the IEC 61499 standard is an excellent approach to tackle these challenges by enabling the design,deployment,and management of CPPS in a model-based engineering *** propose a method for CPPS design based on the IEC 61499 *** method allows designers to embed a bio-inspired anomaly-based host intrusion detection system(A-HIDS)in Edge *** A-HIDS is based on the incremental Dendritic Cell Algorithm(iDCA)and can analyze OPC UA network data exchanged between the Edge devices and detect attacks that target the CPPS’Edge *** study’s findings have practical implications on the industrial security community by making novel contributions to the intrusion detection problem in CPPS considering immune-inspired solutions,and cost-effective security by design system *** to the experimental data,the proposed solution can dramatically reduce design and code complexity while improving application maintainability and successfully detecting network attacks without negatively impacting the performance of the CPPS Edge devices.

关键词： Artificial immune systems Cyber-physical production systems IEC 61499 Function blocks Industrial Internet of Things Anomaly-based host intrusion detection system Model-based engineering

QUANTUM FINANCIAL ECONOMICS——RISK AND RETURNS

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Journal of Systems Science & Complexity 2013年第2期26卷 187-200页

作者： goncalves Carlos Pedro Instituto Superior de Ciencias Socials e Politicas-Technical University of Lisbon

Financial volatility risk and its relation to a business cycle-related intrinsic time is addressed through a multiple round evolutionary quantum game equilibrium leading to turbulence and multifractal signatures in the financial returns and in the risk *** model is simulated and the results are compared with actual financial volatility data.

关键词：金融风险量子经济学多重签名博弈均衡内部时间经济周期