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Fundamental Research 2024年第2期4卷 237-245页

作者： Yanxia rao Bo Peng Department of Laboratory Animal Science MOE Frontiers Center for Brain ScienceFudan UniversityShanghai 200032China Department of Neurosurgery Huashan HospitalInstitute for Translational Brain ResearchState Key Laboratory of Medical NeurobiologyMOE Frontiers Center for Brain ScienceMOE Innovative Center for New Drug Development of Immune Inflammatory DiseasesFudan UniversityShanghai 200000China Co-Innovation center of Neuroregeneration Nantong UniversityNantongJiangsu 226001China

Microglia are resident immune cells in the central nervous system(CNS)that play vital roles in CNS development,homeostasis and disease *** defects in microglia lead to microglial dysfunction,which in turn leads to neurological *** correction of the specific genetic defects in microglia in these disorders can lead to therapeutic *** genetic defect correction approaches are dependent on viral vectorbased genetic defect ***,the viruses used in these approaches,including adeno-associated viruses,lentiviruses and retroviruses,do not primarily target microglia;therefore,viral vector-based genetic defect corrections are ineffective in *** replacement is a novel approach to correct microglial genetic defects via replacing microglia of genetic defects with allogenic healthy *** this paper,we systematically review the history,rationale and therapeutic perspectives of microglia replacement,which would be a novel strategy for treating CNS disorders.

关键词： Microglia Replacement Microglia replacement Microglia depletion Microglia-free niche CSF1R

Modeling Study of the Particle Pinning Effect on the Grain Boundary Movement

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Journal of Iron and Steel Research International 2011年第S1期18卷 342-345页

作者： WANG Xue-lun 1,FU Li-ming 2,WANG Wei 3,JIA Zhi-xin 1 (1.Rizhaosteel technology center,Rizhao Iron and Steel Co Ltd.Rizhao 276806,china 2.School of Materials Science and Engineering,shanghai Jiaotong University,shanghai 200240 china 3 Department of Structural Steels,baosteel Research Institute,shanghai 201900,china) Rizhao Iron & Steel Co Ltd Rizhaosteel Technol Ctr Rizhao 276806 Peoples R China shanghai Jiao Tong Univ Sch Mat Sci & Engn Shanghai 200240 Peoples R China baosteel Res Inst Dept Struct Steels Shanghai 201900 Peoples R China

In this work,based on the classical grain boundary (GB) formula and the principle of work-energy conversion,a new physically-based model has been developed to predict the particle pinning force concerning the interaction between second phase particles (SPPs) and the moving *** effect of particles pinning on the GB movement is *** modeling results can be applied to quantitatively determine the critical numbers of SPPs required for complete pining the grain growth,such as the critical SPPs number of the unit GB area,the critical number for single grain stagnation,the critical volume fraction of particles at a given particle *** predictions are in good agreement with the experimental results by Gladman.

关键词： the second-phase particle pinning force physical-based model

The new challenges for the development of NH_(3)-SCR catalysts under new situation of energy transition in power generation industry

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Chinese Chemical Letters 2024年第6期35卷 95-103页

作者： Feibin Wei Yongfang rao Yu Huang Wei Wang Hui Mei Science and technology on Thermostructural Composite Materials Laboratory School of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi’an 710072China Key Laboratory of Aerosol Chemistry and Physics State Key Laboratory of Loess and Quaternary Geology(SKLLQG)Institute of Earth EnvironmentChinese Academy of SciencesXi’an 710061China center of Excellence in Quaternary Science and Global Change Chinese Academy of SciencesXi’an 710061China University of Chinese Academy of Sciences Beijing 100049China Department of Environmental Science and Engineering Xi’an Jiaotong UniversityXi’an 710049China

NH_(3)-SCR was one of the most promising de NO_x technologies and it has been widely applied in industrial NO_x ***,with the further development of energy transformation in power generation sector,the development of NH_(3)-SCR catalysts is facing some new *** is becoming an urgent problem to solve low catalytic activity and stability of NH_(3)-SCR catalysts at the working condition of ultra-low temperature(≤200℃)and high concentrations of H_(2)O+SO_(2) due to the gradual deployment of new energy power ***,the traditional coal-fired power plants would need flexible operation with the increasing share of renewable energy *** NH_(3)-SCR catalysts which were applied in coal-fired power industry would be requested to work in a wide temperature window from 200℃ to 500℃ in the near ***,in this review,we summarized the progress of NH_(3)-SCR catalysts in solving these different industrial problems in recent *** the research directions which were deserved to be focused on the development of NH_(3)-SCR catalysts for the energy transition of power generation sector are proposed.

关键词： NH_(3)-SCR NOx reduction Power generation Ultra-low temperature Wide temperature windows

An Immune-Inspired Approach with Interval Allocation in Solving Multimodal Multi-Objective Optimization Problems with Local Pareto Sets

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Computers, Materials & Continua 2024年第6期79卷 4237-4257页

作者： Weiwei Zhang Jiaqiang Li Chao Wang Meng Li Zhi rao College of Computer Science and technology Zhengzhou University of Light IndustryZhengzhou450001China technology Research and Development center Jilin Tobacco Industry Company LimitedChangchun130031China College of Tobacco Science and Engineering Zhengzhou University of Light IndustryZhengzhou450001China Raw Material Department Hongyun Honghe Tobacco(Group)CompanyKunming650202China

In practical engineering,multi-objective optimization often encounters situations where multiple Pareto sets(PS)in the decision space correspond to the same Pareto front(PF)in the objective space,known as Multi-Modal Multi-Objective Optimization Problems(MMOP).Locating multiple equivalent global PSs poses a significant challenge in real-world applications,especially considering the existence of local *** identifying and locating both global and local PSs is a major *** tackle this issue,we introduce an immune-inspired reproduction strategy designed to produce more offspring in less crowded,promising regions and regulate the number of offspring in areas that have been thoroughly *** approach achieves a balanced trade-off between exploration and ***,we present an interval allocation strategy that adaptively assigns fitness levels to each *** strategy ensures a broader survival margin for solutions in their initial stages and progressively amplifies the differences in individual fitness values as the population matures,thus fostering better population ***,we incorporate a multi-population mechanism that precisely manages each subpopulation through the interval allocation strategy,ensuring the preservation of both global and local *** results on 21 test problems,encompassing both global and local PSs,are compared with eight state-of-the-art multimodal multi-objective optimization *** results demonstrate the effectiveness of our proposed algorithm in simultaneously identifying global Pareto sets and locally high-quality PSs.

关键词： Multimodal multi-objective optimization problem local PSs immune-inspired reproduction

Representation of the Stratospheric Circulation in CRA-40 Reanalysis:The Arctic Polar Vortex and the Quasi-Biennial Oscillation

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Advances in Atmospheric Sciences 2024年第5期41卷 894-914页

作者： Zixu WANG Shirui YAN Jinggao HU Jiechun DENG Rongcai REN Jian rao Key Laboratory of Meteorological Disaster Ministry of Education(KLME)Joint International Research Laboratory of Climate and Environment Change(ILCEC)Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters(CIC-FEMD)Nanjing University of Information Science&TechnologyNanjing 210044China Key Laboratory for Semi-Arid Climate Change of the Ministry of Education College of Atmospheric SciencesLanzhou UniversityLanzhou 730000China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China

The representation of the Arctic stratospheric circulation and the quasi-biennial oscillation(QBO)during the period 1981–2019 in a 40-yr Chinese global reanalysis dataset(CRA-40)is evaluated by comparing two widely used reanalysis datasets,ERA-5 and ***-40 demonstrates a comparable performance with ERA-5 and MERRA-2 in characterizing the winter and spring circulation in the lower and middle Arctic ***,differences in the climatological polar-mean temperature and polar night jet among the three reanalyses are within±0.5 K and±0.5 m s^(–1),*** onset dates of the stratospheric sudden warming and stratospheric final warming events at 10 hPa in CRA-40,together with the dynamics and circulation anomalies during the onset process of warming events,are nearly identical to the other two reanalyses with slight *** contrast,the CRA-40 dataset demonstrates a deteriorated performance in describing the QBO below 10 hPa compared to the other two reanalysis products,manifested by the larger easterly biases of the QBO index,the remarkably weaker amplitude of the QBO,and the weaker wavelet power of the QBO *** pronounced biases are mainly concentrated in the period 1981–98 and largely reduced by at least 39%in 1999–***,particular caution is needed in studying the QBO based on *** three reanalyses exhibit greater disagreement in the upper stratosphere compared to the lower and middle stratosphere for both the polar region and the tropics.

关键词： CRA-40 ERA-5 MERRA-2 Arctic stratosphere the QBO

Modeling of Carbonitride Precipitation in Austenite During Hot Rolling

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Modeling of Carbonitride Precipitation in Austenite During H...

Effects of COVID-19 pandemic on human fertility:A scientometric and visualized evaluation

第五届国际低合金高强度钢会议暨第三届国际超细晶粒钢会议

作者： ZENG Yu WANG Wei (baosteel technology center shanghai 201900 P. R. china e-mail: weiwang@***)

A mathematical model for predicting the precipitation kinetics of carbonitrides in Nb-Ti bearing steel undergoing thermomechanical treatments has been developed on the basis of modified nucleation and

关键词： Carbonitrides Precipitation modeling Austenite Hot rolling

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Genes & Diseases 2024年第4期11卷 113-115页

作者： Xiangxiu Wang Yifan rao Lili Tan Ziqiu Hu Lin Wen Weixi Qin Bingyi Li Keqiao He Tieying Yin Juhui Qiu Yuming Wang Yaokai Chen Xiancai rao Guixue Wang Key Laboratory of Biorheological and technology of the Ministry of Education State and Local Joint Engineering LaboratoryforVascular ImplantsModern LifeScience Experiment Teaching Center at Bioengineering College of Chongqing UniversityChongqing 400030China Department of Microbiology College of Basic Medical SciencesKey Laboratory of Microbial Engineering Under the Educational Committee in ChongqingArmy Medical University(Third Military Medical University)Chongqing 400038China Jinfeng Laboratory Chongqing 401329China Division of Infectious Diseases Chongqing Public Health Medical CenterChongqing 400036China

CovID-19,also known as coronavirus disease 2019,is a novel coronavirus disease with high infectivity,strong heterogeneity,and long incubation period(generally 3-14 days).Its main symptoms and signs include fever,dry cough,nasal congestion,fatigue,disorientation,lymphopenia,and *** short-term and long-term impacts of covID-19 on human health,particularly its effects on human reproduction and offspring development,continue to receive significant concerns,as they may lead to potential sequelae for several decades or even centuries.

关键词： nasal fertility fever

Regulating the electronic structure of Ir single atoms by ZrO_(2)nanoparticles for enhanced catalytic oxidation of formaldehyde at room temperature

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Chinese Chemical Letters 2024年第7期35卷 200-205页

作者： Shiqi Peng Yongfang rao Tan Li Yufei Zhang Jun-ji Cao Shuncheng Lee Yu Huang Key Laboratory of Aerosol Chemistry&Physics State Key Laboratory of Loess and Quaternary Geology(SKLLQG)Institute of Earth EnvironmentChinese Academy of Sciences(CAS)Xi’an 710061China School of Human Settlements and Civil Engineering Xi’an Jiaotong UniversityXi’an 710049China Department of Environmental Science and Engineering Xi’an Jiaotong UniversityXi’an 710049China Faculty of Chemical Engineering Kunming University of Science and TechnologyKunming 650500China School of Environment and Energy South China University of TechnologyGuangzhou 51006China School of Environmental and Municipal Engineering Xi’an University of Architecture and TechnologyXi’an 710055China Institute of Atmospheric Physics Chinese Academy of SciencesBeijing 100190China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong KongChina CAS center for Excellence in Quaternary Science and Global Change Xi’an 710061China

Developing low-loading single-atom catalysts with superior catalytic activity and selectivity in formaldehyde(HCHO)oxidation at room temperature remains ***,ZrO_(2)nanoparticles coupled low-loading Ir single atoms in N-doped carbon(Ir_(1)-N-C/ZrO_(2))was *** optimal Ir_(1)-N-C/ZrO_(2)with 0.25 wt%Ir loading delivers the high HCHO removal and conversion efficiency(>95%)at 20℃,which is higher than that over Ir_(1)-N-C with the same Ir *** specific rate can reach 1285.6 mmol gIr^(-1)h^(-1),surpassing the Ir based catalysts reported to *** functional theory calculation results and electron spin resonance spectra indicate that the introduction of Zr O_(2)nanoparticles modulate the electronic structure of the Ir single atoms,promoting O_(2)activation to·O_(2)^(–).Moreover,the Ir-C-Zr channel is favorable for the dissociation of·O_(2)^(–)to active oxygen atom(*O),and further accelerates the transformation of HCHO and intermediates(dioxymethylene and formates)to CO_(2)and H_(2)*** work provides a facile strategy to design low-loading single-atom catalysts with high catalytic activity toward HCHO oxidation.

关键词： ZrO_(2)nanoparticles Ir single atoms Electronic structure Formaldehyde Catalytic oxidation

Ocean wave directional spectrum estimation using spatio-temporal array of acoustic ranging and current measurement

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Chinese Journal of Acoustics 2024年第3期43卷 311-331页

作者： rao Liang DENG Kai ZHANG Zhaowei WANG Changhong Institute of Acoustics Chinese Academy of SciencesBeijing100190 University of Chinese Academy of Sciences Beijing100049 Beijing Engineering technology Research center of Ocean Acoustic Equipment Beijing100190

An approach to estimate ocean wave directional spectrum using spatio-temporal array of acoustic ranging and current measurement is proposed,and the 5-beam acoustic Doppler current profiler(ADCP)constructs a spatio-temporal array of acoustic ocean surface elevation tracking and acoustic Doppler current velocity measuring for directional wave *** on the linear wave theory and the space-time equivalence principle,the time-space transfer function applicable to the spatio-temporal array is proposed,and then the time delay term is compensated in the calculation of the covariance *** method can reduce the error of the directional spectrum *** results show that for the low signal-to-noise ratio from 0 dB to 5 dB,compared with the 4-beam synchronous array method,this method has a smaller root-mean-square error of the peak estimation of the directional *** field test shows that,compared with the 4-beam synchronous array method,the 5-beam spatio-temporal array method improves the kurtosis index of the directional spectrum from 2.31 to 2.80,and the correlation coefficient between the peak wave direction results of the ADCP and the buoy is increased from 0.80 to 0.83 in mild wave ***,the spatio-temporal array method can increase the degree of freedom of wave measurement,reduce the minimum aperture of the array,and increase the upper cut-off frequency of the estimable directional spectrum.

关键词： spectrum ocean directional