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Tracing overlapping biological signals in mid-infrared using colonic tissues as a model system

World Journal of Gastroenterology 2017年第2期23卷 286-296页

作者： ranjit kumar sahu Ahmad Salman Shaul Mordechai Department of Physics Ben Gurion University Department of Medicine University of Virginia Department of Physics SCE-Shamoon College of Engineering

AIMTo understand the interference of carbohydrates absorbance in nucleic acids signals during diagnosis of malignancy using Fourier transform infrared (FTIR) *** used formalin fixed paraffin embedded colonic tissues to obtain infrared (IR) spectra in the mid IR region using a bruker II IR microscope with a facility for varying the measurement area by varying the aperture available. Following this procedure we could measure different regions of the crypt circles containing different biochemicals. Crypts from 18 patients were measured. Circular crypts with a maximum diameter of 120 μm and a lumen of about 30 μm were selected for uniformity. The spectral data was analyzed using conventional and advanced computational *** the various components that are observed to contribute to the diagnostic capabilities of FTIR, the carbohydrates and nucleic acids are prominent. However there are intrinsic difficulties in the diagnostic capabilities due to the overlap of major absorbance bands of nucleic acids, carbohydrates and phospholipids in the mid-IR region. The result demonstrates colonic tissues as a biological system suitable for studying interference of carbohydrates and nucleic acids under ex vivo conditions. Among the diagnostic parameters that are affected by the absorbance from nucleic acids is the RNA/DNA ratio, dependent on absorbance at 1121 cm-1 and 1020 cm-1 that is used to classify the normal and cancerous tissues especially during FTIR based diagnosis of colonic malignancies. The signals of the nucleic acids and the ratio (RNA/DNA) are likely increased due to disappearance of interfering components like carbohydrates and phosphates along with an increase in amount of *** present work, proposes one mechanism for the observed changes in the nucleic acid absorbance in mid-IR during disease progression (carcinogenesis).

关键词： Spectral interference Fourier transform infrared diagnosis Nucleic acids Malignancy Colonic tissue

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Finger pulp reconstruction with thenar flap: Aesthetic and functional outcome

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Chinese Journal of Traumatology 2020年第5期23卷 307-310页

作者： ranjit kumar sahu Prakash Chandra Kala Pawan kumar Dixit Sourabh Shankar Chakraborty Suresh K Deepti Katrolia Department of Burns and Plastic Surgery All India Institute of Medical SciencesJodhpur342005India

Purpose:Fingertip injuries are common in industrial production activities as well as in domestic *** of pulp hampers daily life *** and aesthetic aspects are important in fingertip *** bone is usually exposed along with soft tissue *** to reconstruct the pulp flap with adequate bulk is ***:We reported a case series of 12 patients with the injury over the volar aspect of distal phalanx of the index or middle *** all cases,laterally based thenar flap was *** flap donor site was closed primarily in most of cases,while 4 patients required skin *** flap was detached between 2e3 *** assessment was done using static and dynamic 2-point discrimination and range of motion at each *** aesthetic outcome was assessed through *** results were analyzed using the unpaired t-test(SPSS version 21).Results:Partial necrosis occurred in 2 cases while rest of flaps survived *** 2-point discrimination ranged from 6e10 mm,mean 8.6 mm;and dynamic 2-point discrimination ranged from 8e10 mm,mean 8.9 *** mean satisfaction score was(4.0±0.55).Conclusion:Thenar flap is a good choice for reconstruction of the finger pulp as it provides the bulk with good functional and aesthetic outcome.

关键词： Finger injuries Finger pulp reconstruction Thenar flap

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Adaptive Tracking Control of an Autonomous Underwater Vehicle

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International Journal of Automation and computing 2014年第3期11卷 299-307页

作者： Basant kumar sahu Bidyadhar Subudhi Centre for Industrial Electronics and Robotics Department of Electrical Engineering National Institute of Technology

This paper presents the trajectory tracking control of an autonomous underwater vehicle(AUV). To cope with parametric uncertainties owing to the hydrodynamic effect, an adaptive control law is developed for the AUV to track the desired trajectory. This desired state-dependent regressor matrix-based controller provides consistent results under hydrodynamic parametric *** of the developed controller is verified using the Lyapunov s direct method. Numerical simulations are carried out to study the efficacy of the proposed adaptive controller.

关键词： Autonomous underwater vehicle(AUV) adaptive control law regressor matrix Lyapunovs stability path following

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Electro-magnetohydrodynamic Flow of Biofluid Induced by Peristaltic Wave： A Non-newtonian Model

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Journal of Bionic Engineering 2016年第3期13卷 436-448页

作者： Gopal Chandra Shit Nayan kumar ranjit Aniruddha Sinha Department of Mathematics Jadavpur University Kolkata - 700032 India Yogoda Satsanga Palpara Mahavidyalaya Purba Medinipur - 721458 India

This article aims to develop a mathematical model for peristaltic transport of magnetohydrodynamic flow of biofluids through a micro-channel with rhythmically contracting and expanding walls under the influence of an applied electric field. The couple stress fluid model is considered to represent the non-Newtonian characteristics ofbiofluids. The velocity slip condition at the channel walls is taken into account because of the hyclrophilic/hydrophobic interaction with negatively charged walls. The essential features of the electromagnetohydrodynamic flow of biofluid through micro-channels are clearly highlighted in the variations of the non-dimensional parameters of the physical quantities of interest such as the velocity, wall shear stress, pressure gradient, pressure rise per wave length, frictional force at the channel walls and the distribution of stream function. It reveals that the flow ofhiofluid is appreciably influenced by the sufficient strength of externally applied magnetic field and electro-osmotic parameter. The velocity slip condition reduces the frictional force at the channel wall. Moreover, the formation of the trapping bolus strongly depends on electro-osmotic parameter and magnetic field strength.

关键词： peristaltic transport couple stress fluid magnetohydrodynamics electro-osmosis

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DYNAMICAL BEHAVIOR OF AN INNOVATION DIFFUSION MODEL WITH INTRA-SPECIFIC COMPETITION BETWEEN COMPETING ADOPTERS

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Acta Mathematica Scientia 2022年第1期42卷 364-386页

作者： Rakesh kumar Anuj kumar SHARMA Govind Prasad sahu Department of Applied Sciences Shaheed Bhagat Singh State UniversityFerozepurPunjab 152004India Department of Mathematics L.R.D.A.V.CollegeJagraonLudhianaPunjab 142026India Center for Basic Sciences Pt Ravishankar Shukla UniversityRaipur(Chhattisgarh).India

In this paper,we proposed an innovation diffusion model with three compartments to investigate the diffusion of an innovation(product)in a particular *** model exhibits two equilibria,namely,the adopter-free and an interior *** existence and local stability of the adopter-free and interior equilibria are explored in terms of the effective Basic Influence Number(BIN)R_(A).It is investigated that the adopter free steady-state is stable if R_(A)<*** consideringτ(the adoption experience of the adopters)as the bifurcation parameter,we have been able to obtain the critical value ofτresponsible for the periodic solutions due to Hopf *** direction and stability analysis of bifurcating periodic solutions has been performed by using the arguments of normal form theory and the center manifold *** numerical simulations in the support of analytical results have been presented.

关键词： intra-specific competition basic influence number local stability Hopf-bifurcation normal form theory center manifold theorem

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Maize gets an iron boost:Biofortification breakthrough holds promise to combat iron deficiency

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Journal of Integrative Plant Biology 2024年第4期66卷 635-637页

作者： Sunil kumar sahu State Key Laboratory of Agricultural Genomics Key Laboratory of GenomicsMinistry of AgricultureBGI ResearchShenzhen 518083China BGI Research Wuhan 430074China

Micronutrient deficiencies affect more than two billion people worldwide,resulting in poor health,developmental issues,and even *** deficiency is one of the most prevalent micronutrient deficiencies worldwide and impa... 详细信息

关键词： population breakthrough holds

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Modeling the transmission dynamics of a time-delayed epidemic model with saturated treatment rate

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International Journal of Biomathematics 2023年第7期16卷 11-45页

作者： ranjit kumar Upadhyay Sattwika Acharya Department of Mathematics&Computing Indian Institute of Technology(Indian School of Mines)Dhanbad Jharkhand-826004 India

In this paper,an attempt has been made to explore a new delayed epidemiological model assuming that the disease is transmitted among the susceptible population and possessing nonlinear incidence function along with a saturated treatment *** attention is paid to the positivity and boundedness of the solutions and the bifurcation of the dynamical system as *** reproduction number is being calculated,and considering the latent period as a bifurcation parameter,it has been examined that a Hopf-bifurcation occurs near the endemic equilibrium point while the parameter attains critical *** have also discussed the stability and direction of Hopf-bifurcation near the endemic equilibrium point,the global stability analysis and the optimal control *** conclude that the system reveals chaotic dynamics through a specific time-delay *** simulations are being performed in order to explain the accuracy and effectiveness of the acquired theoretical results.

关键词： Infectious disease treatment rate chaotic dynamics bifurcation theory incidence function transmission dynamics global stability optimal control

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Structural Tuning of Low Band Gap Intermolecular Push/Pull Side-chain Polymers for Organic Photovoltaic Applications

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Chinese Journal of Polymer Science 2017年第9期35卷 1073-1085页

作者： Ansuman Nayak P.S. Rama Sreekanth Santosh kumar sahu Duryodhan sahu Department of Chemistry National Institute of Science and Technology Palur Hills Berhampur Odisha India 761008 Department of Chemistry Gandhi Institute of Engineering and Technology Gunpur Odisha India Department of Mechanical Engineering National Institute of Science and Technology Palur Hills Berhampur Odisha India 761008

A series of novel low band gap donor-acceptor （D-A） type organic co-polymers （BT-F-TPA, BT-CZ-TPA and BT-SI-TPA） consisting of electron-deficient acceptor blocks both in main chains （M1） and at the pendant （M2） were polymerized with different electron rich donor （M3-M5） blocks, i.e., 9,9-dihexyl-9H-fluorene, N-alkyl-2,7-carbazole, and 2,6-dithinosilole, respectively, via Suzuki method. These polymers exhibited relatively low band gaps （1.65-1.88 eV） and broad absorption ranges （680-740 nm）. Bulk heterojunction （BHJ） solar cells incorporating these polymers as electron donors, blended with [6,6]-phenyl-C61-butyric acid methyl ester （PC61BM） or [6,6]-phenyl-Cvl-butyric acid methyl ester （PC71BM） as electron-acceptors in different weight ratios were fabricated and tested under 100 mW/cm2 of AM 1.5 with white-light illumination. The photovoltaic device containing donor BT-SI-TPA and acceptor PC71BM in 1：2 weight ratio showed the best power conversion efficiency （PCE） value of 1.88%, with open circuit voltage （Voc） = 0.75 V, short circuit current density （Jsc） = 7.60 mA/cm2, and fill factor （FF） = 33.0%.

关键词： Polymer solar cells Low band gap Conducting polymers Charge transfer Donor-acceptor Bulk heterojunctionsolar cell

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Local binary pattern-based reversible data hiding

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CAAI Transactions on Intelligence Technology 2022年第4期7卷 695-709页

作者： Monalisa sahu Neelamadhab Padhy Sasanko Sekhar Gantayat Aditya kumar sahu Department of Computer Science and Engineering School of Engineering and TechnologyGIET UniversityGunupurOdishaIndia Department of Computer Science and Engineering GMRITRajamAndhra PradeshIndia Department of CSE Vignan's Foundation for Science Technology and ResearchVadlamudiAndhra PradeshIndia

A novel local binary pattern-based reversible data hiding(LBP-RDH)technique has been suggested to maintain a fair symmetry between the perceptual transparency and hiding *** embedding,the image is divided into various 3×3 ***,using the LBP-based image descriptor,the LBP codes for each block are ***,the obtained LBP codes are XORed with the embedding bits and are concealed in the respective blocks using the proposed pixel readjustment ***,each cover image(CI)pixel produces two different stego-image ***,during extraction,the CI pixels are restored without the loss of a single bit of *** outcome of the proposed technique with respect to perceptual transparency measures,such as peak signal-to-noise ratio and structural similarity index,is found to be superior to that of some of the recent and state-of-the-art *** addition,the proposed technique has shown excellent resilience to various stego-attacks,such as pixel difference histogram as well as regular and singular ***,the out-off boundary pixel problem,which endures in most of the contemporary data hiding techniques,has been successfully addressed.

关键词： hiding capacity(HC) local binary pattern(LBP) peak signal-to-noise ratio(PSNR) reversible data hiding

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Ayurveda and in silico Approach: A Challenging Proficient Confluence for Better Development of Effective Traditional Medicine Spotlighting Network Pharmacology

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Chinese Journal of Integrative Medicine 2023年第5期29卷 470-480页

作者： Rashmi sahu Prashant kumar Gupta Amit Mishra Awanish kumar Department of Balroga Shri NPA Govt.Ayurveda CollegeRaipur(492010)ChhattisgarhIndia Ayurinformatics Lab Department of KaumarabhrityaAll India Institute of AyurvedaSarita ViharNew Delhi(110076)India Cellular and Molecular Neurobiology Unit Indian Institute of TechnologyJodhpur(342037)RajasthanIndia Department of Biotechnology National Institute of TechnologyRaipur(492010)ChhattisgarhIndia

Coalescence of traditional medicine Ayurveda and in silico technology is a rigor for supplementary development of future-ready effective traditional medicine. Ayurveda is a popular traditional medicine in South Asia, emanating worldwide for the treatment of metabolic disorders and chronic illness. Techniques of in silico biology are not much explored for the investigation of a variety of bioactive phytochemicals of Ayurvedic herbs. Drug repurposing, reverse pharmacology, and polypharmacology in Ayurveda are areas in silico explorations that are needed to understand the rich repertoire of herbs, minerals, herbo-minerals, and assorted Ayurvedic formulations. This review emphasizes exploring the concept of Ayurveda with in silico approaches and the need for Ayurinformatics studies. It also provides an overview of in silico studies done on phytoconstituents of some important Ayurvedic plants, the utility of in silico studies in Ayurvedic phytoconstituents/formulations, limitations/challenges, and prospects of in silico studies in Ayurveda. This article discusses the convergence of in silico work, especially in the least explored field of Ayurveda. The focused coalesce of these two domains could present a predictive combinatorial platform to enhance translational research magnitude. In nutshell, it could provide new insight into an Ayurvedic drug discovery involving an in silico approach that could not only alleviate the process of traditional medicine research but also enhance its effectiveness in addressing health care.

关键词： Ayurveda in silico approach conﬂuence challenge effective therapeutics

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