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Journal of Life Sciences 2011年第10期5卷 850-855页

作者： rangareddygari manohar reddy Pathapalli Muneerappa Muniswamy reddy Gangadharaiah Lokesh Reddivari Dayananda reddy Cheluri Siva reddy Andanur Manjula Vankadara Sivaprasad P2 Basic Seed Farm Central Silk Board Parigi 515261 India Central Tasar Research ＆ Training Institute Central Silk Board Ranchi 835303 India Silkworm Seed Production Centre Central Silk Board Hindupur 515202 India National Silkworm Seed Organization Central Silk Board Bangalore 560068 India

Commercially important polyphagous tropical tasar silk insect, Antheraea mylitta Drury is distributed along central India （12-31 ° N latitude, 72-96° E longitude）, which on adaptation formed in to forty four ecoraces of varied phenotypes. Its wild ecoraces like Raily, Modal, Jata, Sarihan, Laria, Bhandara and Andhra, besides domesticated Daba and Sukinda are contributing for livelihood of forest based aboriginals. However, the deforestation and extensive collection of nature grown cocoons led to declination of wild population and even have endangered few ecoraces. The government and Non Government Organizations （NGOs）, although promote ecorace conservation, it could upkeep the insect wildlife only to limited extent. But the forest department with associated self help societies has advantage in conserving tasar insect as prospective forest wealth, with better knowledge and access to its habitats. The co-ordinate efforts from forest, sericulture departments to participate native aboriginals of such societies can facilitate conserving tasar-biodiversity as most feasible forest associated resource.

关键词： Antheraea mylitta conservation ecoraces forest wealth tasar biodiversity.

Management of proximal tibial stress fracture associated with advanced knee osteoarthritis:A systematic review

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Chinese Journal of Traumatology 2024年第3期27卷 147-152页

作者： Mukesh Kumar Saini Mahendra Singh Devendra Singh Prem manohar Seervi Pera Jayavardhan reddy Neelam Ramana reddy Department of Orthopaedics Dr SN Medical CollegeJodhpur342011India Department of Orthopaedics Star HospitalsB Block Banjara HillsHyderabad500034India

Purpose:Tibial stress fracture associated with knee osteoarthritis is an unusual and difficult clinical *** is no clear existing treatment guideline for this uncommon clinical *** aim of this study is to review the impact of various treatment options for patients with advanced knee osteoarthritis associated with proximal tibial stress ***:The study was performed using the databases of PubMed and *** index for non-randomized studies score was used to evaluate the included studies’*** concluded data included the treatment approach,reported outcome measure,and time to fracture *** literature search was started in December 2021 and accomplished in January 2022.A narrative description of the different methods and comparison of their results were ***:Out of total assessed 69 studies,9 studies were included in our *** commonest treatment approach used was total knee arthroplasty by long tibial stem *** mean preoperative knee society score and knee functional score were 30.62 and 23.17,*** mean postoperative knee society knee score was 86.87,while the functional score was *** average reported time to achieve fracture union was 4 months(a range of 2.07-5.50 months).Conclusion:The optimal clinical outcome for treating either acute or mobile tibial stress fracture in patients with advanced knee osteoarthritis can be achieved with long stem total knee ***,due to heterogeneity of data,comparison of different treatment options for chronic proximal tibial stress fracture mal-union/non-union coexisting with knee osteoarthritic and such inferences need to be judged cautiously.

关键词： Tibial stress fracture Knee osteoarthritis Total knee arthroplasty

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American Journal of Computational Mathematics 2016年第1期6卷 17-22页

作者： Pushpalatha Sarla Mallikarjuna reddy Doodipala manohar Dingari Department of Engineering Mathematics GITAM University Hyderabad Campus Hyderabad India

The paper focuses on measuring self-similarity using few techniques by an index called Hurst index which is a self-similarity parameter. It has been evident that Internet traffic exhibits self-similarity. Motivated by this fact, real time web users at various centers considered here as traffic and it has been examined by various methods to test the self-similarity. The results from the experiments carried out verify that the traffic examined in the present study is self similar using a new method based on some descriptive measures;for example percentiles have been applied to compute Hurst parameter which gives intensity of the self-similarity. Numerical results and analysis we discussed and presented here play a significant role to improve the services at web centers in the view of quality of service (QOS).

关键词： Long-Range Dependence Self-Similarity Poisson Process Percentiles Hurst Parameter

Dysregulated miRNA Associated with Transcription Factors of Insulin Gene Expression in Chronic Pancreatitis

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Open Journal of Endocrine and Metabolic Diseases 2016年第10期6卷 205-227页

作者： K. Murali manohar M. Sasikala P. Pavan Kumar G. V. Rao D. Nageshwar reddy Institute of Basic Science and Translational Research Asian Healthcare Foundation Hyderabad India Asian Institute of Gastroenterology Somajiguda Hyderabad India

Background/Aim: MicroRNAs with regulatory functions in gene expression are implicated in different diseases. The present study investigated differentially expressed miRNAs that possibly influence transcription factors involved in insulin gene expression in Chronic Pancreatitis (CP) employing bioinformatics approaches. Methods: Pancreatic tissues were collected from CP patients undergoing partial pancreatectomy (n = 16) and controls (n = 15) undergoing resections for non-pancreatic malignancies. MiRNA profiles obtained using microarrays were validated by qRT-PCR. Target search involving miRWalk and TarBase as well as functional annotation employing KEGG (Kyoto encyclopedia of genes and genomes) and DAVID (Database for Annotation) databases were performed. Ingenuity pathway analysis (IPA) was used to construct networks relating miRNAs to their target genes. mRNA and proteins related to insulin gene transcription factors and hormones were evaluated by qRT-PCR and western blotting followed by confirmation upon immunofluorescent staining. Results: Microarray data revealed 10 up-regulated and 15 down-regulated miRNAs in CP as compared to controls (Log2 FC > 2). Bioinformatic analysis showed 8399 target genes and KEGG pathway analysis suggested a role for the dysregulated miRNAs in modulating cytokine signaling, fibrosis, JAK-STAT signaling and insulin synthesis. IPA analysis suggested a simplified network attributing dysregulated miRNAs to NFκB-dependent cytokine signaling. Further, associations could be noted between miRNA 200b with Maf A, 138-1 with Neuro D and 27b with FoxO1. Decreases in mRNA levels of Pdx1, Neuro D and increases of Maf A and FoxO1 transcription factors could be noted (P Conclusion: Our results identified dysregulation of miRNAs 138-1, 27b and 200b which were found to be associated with insulin gene transcription factors Neuro D, FoxO1 and Maf A respectively.

关键词： MicroRNAs Transcription Factors Networks β-Cell Dysfunction

Are Truckers Being over Stigmatized as HIV Carriers in India? Evidences from Behavioral and Biological Cross-Sectional Surveys among Clients of Female Sex Workers

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Open Journal of Preventive Medicine 2015年第3期5卷 85-91页

作者： Damodar Sahu Sowmya Ramesh Ram manohar Mishra K. Srikanth reddy Reena Bharadwaj Niranjan Saggurti Arvind Pandey Mandar Mainkar Bitra George National Institute of Medical Statistics ICMR New Delhi India Population Council New Delhi India National AIDS Research Institute Pune India FAMILY Health International New Delhi India

This paper examines whether truckers have been over-stigmatized as HIV carriers in the country. Data were taken from cross-sectional surveys of clients of female sex workers conducted in 2006-2007 in 12 districts of the country. A total 4822 clients of female sex workers were covered in the survey. Low-income skilled/semi-skilled men, including non-agricultural/casual labor, and petty businessmen/small shop owners, have the largest share in the clients’ population. There was no significant difference between truckers and other sub-group of clients’ population in terms of consistent condom use with female sex workers and prevalence of HIV or STI. These evidences suggest that the contribution of truckers in HIV epidemic in India might to similar to other sub-groups of clients’ population. Thus, truckers might have been over-stigmatized as HIV carriers in the country. However, there is no doubt that truckers constitute an extremely important target group for the HIV prevention programs and these efforts must be continued to prevent new HIV infections in the country.

关键词： Clients Truckers Sex Workers India