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World Journal of Clinical Cases 2023年第24期11卷 5823-5829页

作者： tao Wang Yi-Yu Shen Graduate School Zhejiang Chinese Medical UniversityHangzhou 310053Zhejiang ProvinceChina Department of Hepatobiliary Surgery The Second Affiliated Hospital of Jiaxing UniversityJiaxing 314051Zhejiang ProvinceChina

BACKGROUND This is the first report of an ROS1-CENPW fusion gene in pancreatic *** SUMMARY A 77-year-old woman with a pancreatic tumor and multiple liver metastases was admitted to our *** testing revealed the presence of the ROS1-CENPW fusion gene,a rare fusion gene that has not been previously reported in the field of pancreatic *** patient received crizotinib plus AG(albumin paclitaxel plus gemcitabine)*** treatment,the patient’s condition stabilized,and her prognosis was *** The ROS1-CENPW gene treatment regimen used in this case is an excellent treatment option that provides new hope for patients with advanced pancreatic cancer and similar genetic *** date,owing to the rarity of the ROS1-CENPW fusion gene,our team has encountered only a single ***,the efficacy of crizotinib plus AG chemotherapy in patients with pancreatic acinar cell carcinoma harboring the ROS1-CENPW fusion gene requires further validation.

关键词： ROS1-CENPW Pancreatic acinar cell carcinoma Crizotinib Gemcitabine Albumin paclitaxel Case report

Measuring visibility using digital photography

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Chinese Science Bulletin 1999年第12期44卷 1130-1134页

作者： Xingsheng Xie Shanchang tao Xiuji Zhou Univ Sci & Technol China Hefei 230026 Peoples R China Chinese Acad Meteorol Sci Beijing 100081 Peoples R China

An automatic digital photography visibility system (DPVS) is presented, which can directly measure and monitor horizontal visibility during daytime through digital shooting. After shooting a scene of given black object and background via its CCD digital camera, the system can capture and transfer photographic images in the camera to a computer, as well as process the digital images and calculate the value of visibility. The formulas for calculating visibility with this method and analysing the effect of non-black object on measured results have also been derived . And then the comparison of DPVS observations with a Lidar-visibility measurements has been carried out. The results show that the average deviation and relative average deviation of visibility acquired by DPVS from lidar-visibility measurements are respectively within 0.927 km and 6.68%.

关键词： digital shooting image processing visibility comparing experiment.

Catalytic Dehydration of 4-Hydroxy-3-hexanone to 4-Hexen-3-one over HZSM-5 Zeolite

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China Petroleum Processing & Petrochemical Technology 2013年第4期15卷 87-91页

作者： Huang Kai Zheng Haitao tao Keyi School of Environmental and Chemical Engineering Tianjin Polytechnic University Institute of New Catalytic Materials Science College of Chemistry Nankai University

A study on catalytic dehydration of 4-hydroxy-3-hexanone （HH） to 4-hexen-3-one （HO） was carried out through conversion of HH over HZSM-5 zeolite catalyst in a fixed-bed reactor （FBR） operating under almospheric pressure. The test indicated a relatively high activity of the HZSM-5 zeolite capable of achieving a HH conversion of 99.2% and a HO yield of 83.5%. Catalyst deactivation could be prevented by increasing the reaction temperature by 10 ＂C for every 20 h and adding 2.0% of piperidine in the feed. A catalyst stability test （for 100 h） in FBR showed that the catalyst was active even after 100 h of time-on-stream with HH conversion remaining at 99.2% and HO yield still reaching over 83.5%. Regenera- tion experiment showed that the regenerated catalyst demonstrated a catalytic performance comparable to the fresh one.

关键词： HZSM-5 dehydration 4-hydroxy-3-hexanone deactivation regeneration

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基于STM32的无线运动监测装置设计

天津理工大学学报 2025年第2期41卷 88-91页

作者：胡徐胜刘娟陶彬彬马鞍山市无线传感网与智能感知工程技术研究中心皖江工学院电气信息工程学院马鞍山职业技术学院电气信息工程学院

为了能够稳定采集、记录并显示使用者的心电信息、体表温度和运动信息，采用STM32F103C8T6单片机设计控制系统。系统由温度传感器、六轴陀螺仪、心电检测等模块组成，采用电池供电并使用稳压模块。设计算法通过接触式温度传感器LMT70和... 详细信息

为了能够稳定采集、记录并显示使用者的心电信息、体表温度和运动信息，采用STM32F103C8T6单片机设计控制系统。系统由温度传感器、六轴陀螺仪、心电检测等模块组成，采用电池供电并使用稳压模块。设计算法通过接触式温度传感器LMT70和高精度模拟前端芯片ADS1292实现对人体运动信息的监控。ADS1292通过采集生物电信号再经过滤波算法处理可以将使用者的心电信号传入控制器。读取MPU6050加速度传感器数据得到使用者的行走路程，再根据步频得到步数从而达到计步要求。通过无线模块同步上传，实现各种数据在服务器端达到更加直观的显示。通过实际测试表明，所采用的方案实际有效，实现了心率监测、运动计步等设计要求。

关键词：运动监测 STM32 LMT70 温度传感器 MPU6050

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Non-normal Hasemann Boundary Value Problem

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Wuhan University Journal of Natural Sciences 2001年第3期6卷 649-651页

作者： Cai Hao-tao Du Jin-yuan Coll. of Mathematics and Statistics Wuhan University Wuhan 430072 China

We will discuss the non-normal Hasemann boundary value problem: we may find these results are coincided with those of normal Hasemann boundary value problem and non-normal Riemann boundary value problem.

关键词： non-normal positive transformation canonical function

Thermal Rectification in Graded Nonlinear Transmission Lines

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Chinese Physics Letters 2011年第12期28卷 160-162页

作者： XU Wen CHEN Wei-Zhong tao Feng Key Laboratory of Modern Acoustics(Ministry of Education)and Institution of Acoustics Nanjing UniversityNanjing 210093 School of Electrical Engineering and Information Anhui University of TechnologyMa'anshan 243002

We consider heat conduction in a nonlinear inductance-capacitance(LC)transmission line with an inductance gradient by adding white-noise *** is found that the heat flux in the direction of inductance decrease is larger than that in the direction of inductance *** the low-inductance end is at higher temperature,the phonon density decreases due to conversion to high-frequency phonons,which can not move to the high-inductance end due to its lower cutoff ***,when the high-inductance end is at higher temperature,the loss of phonon density can be compensated for because some high-frequency phonons can move to the low-inductance end dur to its higher cutoff *** leads to the asymmetry of energy *** shows that this asymmetry exists in a particular range of temperatures,and increases with the increase of the difference between heat baths and the inductance gradient.

关键词： phonon Graded Nonlinear

Anthocyanin can arrest the cone photoreceptor degeneration and act as a novel treatment for retinitis pigmentosa

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International Journal of Ophthalmology(English edition) 2016年第1期9卷 153-158页

作者： Ye tao tao Chen Guo-Qing Yang Guang-Hua Peng Zhong-Jun Yan Yi-Fei Huang Department of Ophthalmology General Hospital of Chinese PLA Department of Clinical Aerospace Medicine the Fourth Military Medical University Department of Neurosurgery Tangdu Hospital the Fourth Military Medical University

Retinitis pigmentosa（RP）is a group of heterogeneous inherited retinal diseases that is characterized by primary death rod photoreceptors and the secondary loss of *** degeneration of cones causes gradual constriction of visual fields,leaving the central islands that are eventually snuffed *** indicate that the hyperoxia causes oxidative damage in the retina and contributes to the cone death of ***,abundant reactive oxidative species（ROS）which are generated in cones may result in mitochondria membrane depolarization,which has been ascribed a central role in the apoptotic process and has been proposed to act as a forward feeding loop for the activation of downstream *** is a potent antioxidant which has been evidenced to be able to counteract oxidative damages,scavenge surplus ROS,and rectify abnormities in the apoptotic *** together with its ability to attenuate inflammation which also contributes to the etiology of RP,it is reasonable to hypothesize that the anthocyanin could act as a novel therapeutic strategy to retard or prevent cone degeneration in RP retinas,particularly if the treatment is timed appropriately and delivered *** pharmacological investigations will identify the anthocyanin as an effective candidate for PR therapy and refinements of that knowledge would ignite the hope of restoring the visual function in RP patients.

关键词： retinitis pigmentosa reactive oxidativespecies apoptosis cone photoreceptor anthocyanin

Landau damping of electrons with bouncing motion in a radio-frequency plasma

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Chinese Physics B 2021年第12期30卷 484-494页

作者： Jun tao Nong Xiang Yemin Hu Yueheng Huang Institute of Plasma Physics Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China University of Science and Technology of China Hefei 230026China Advanced Energy Research Center Shenzhen UniversityShenzhen 518060China Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China

One-dimensional particle simulations have been conducted to study the interaction between a radio-frequency electrostatic wave and electrons with bouncing *** is shown that bounce resonance heating can occur at the first few harmonics of the bounce frequency(nω_(b),n=1,2,3,...).In the parameter regimes in which bounce resonance overlaps with Landau resonance,the higher harmonic bounce resonance may accelerate electrons at the velocity much lower than the wave phase velocity to Landau resonance region,enhancing Landau damping of the ***,Landau resonance can increase the number of electrons in the lower harmonic bounce resonance *** electrons can be efficiently *** result might be applicable for collisionless electron heating in low-temperature plasma discharges.

关键词： first few harmonics bounce resonance Landau resonance resonance overlaps

Effect of silencing Bcl-2 expression by small interfering RNA on radiosensitivity of gastric cancer BGC823 cells

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Asian Pacific Journal of Tropical Medicine 2013年第1期6卷 49-52页

作者： Hong-tao Liu Chun-Lei Lu Department of General Surgery Zhengzhou People's Hospital Department of Gastrointestinal Surgery Liberation Army 101 Hospital

Objective:To explore the influence of silencing Bcl-2 expression by small interfering RNA（siRNA） on Bcl-2 protein expression,cell apoptosis rale and radiosensilivity of gastric cancer BCC823 ***:siRNA segment for Bcl-2 gene was designed and synthesized,then was induced into gastric cancer BGC 823 cells by liposome ***-2 protein expression was detected by Western *** X radiation,flow cytometry and clone forming assay were used to determine the effects of RNA interference on BGC823 cell apoptosis rate and radiosensitivity. Result:After the transfection of Bcl-2 siRNA,the positive expression rate of Bcl-2 protein in BGC823 cells was（35.45±2.35）%.Compared with the control group and negative siRNA transfection group,the rate was significantly decreased（Pransfection group（P0,D4 and SF2 values in Bcl-2 siRNA1 transfection group were all lower than those in the control *** radiosensitivity ratio was 1.28（the ratio of D0） and 1.60（the ratio of D4）.Conclusions:Specific siRNA of Bcl-2 gene can effectively inhibit the expression of Bcl-2 gene,enhance the radiosensitivity and apoptosis of gastric cancer BGC823 cells,having good clinical application perspective.

关键词： Gastric cancer BGC823 cell Bcl-2 Radiosensitization RNA interference

Engineered virus-like particles:paving the way for effective somatic genome editing

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Signal Transduction and Targeted Therapy 2022年第9期7卷 3158-3160页

作者： Chenya Zhuo Yu tao Mingqiang Li Laboratory of Biomaterials and Translational Medicine Center for NanomedicineThe Third Alated HospitalSun Yat-sen UniversityGuangzhouChina Guangdong Provincial Key Laboratory of Liver Disease Research GuangzhouChina

A recent publication in Cell describes the development and application of engineered virus-like particles(eVLPs)that effh-ciently package and deliver therapeutic gene-editing proteins,including base editors(BEs)and Cas9 nuclease,with the ability to overcome cargo packaging,release,and localization bottlenecks,representing potentially *** for delivering gene-editing tools of therapeutic interest.

关键词： overcome representing base