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Biochar alleviates apple replant disease by reducing the growth of Fusarium oxysporum and regulating microbial communities

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Horticultural Plant Journal 2024年第3期10卷 657-671页

作者： Yinghao Liu Can Wang ran chen Weitao Jiang Yun Li chengmiao Yin Yanfang Wang Zhiquan Mao College of Chemistry and Material Science Shandong Agricultural UniversityTaianShandong 271018China State Key Laboratory of Crop Biology/College of Horticultural Science and Engineering Shandong Agricultural UniversityTaianShandong 271018China

Apple replant disease(ARD)negatively affects plant growth and reduces yields in replanted *** this study,biochar was applied to apple replant soil with Fusarium *** aim was to investigate whether biochar could promote plant growth and alleviate apple replant disease by reducing the growth of harmful soil microorganisms,changing soil microbial community structure and improving the soil *** experiment included five treatments:apple replant soil(CK),methyl bromide fumigation apple replant soil(FM),replant soil with biochar addition(2%),replant soil with *** spore solution(8×10^(7)spores·mL^(-1)),and replant soil with biochar and *** spore solution *** biomass,the activity of antioxidant enzymes in the leaves and roots,and soil environmental variables were *** community composition and community structure were analyzed using 16SrDNA and ITS2 gene *** significantly reduced the abundance of *** and increased soil microbial diversity and *** also increased the soil enzyme activities(urease,invertase,neutral phosphatase,and catalase),the biomass(plant height,fresh weight,dry weight)and the activity of antioxidant enzymes(superoxide dismutase,peroxidase,and catalase).The root indexes of apple seedlings was also increased in replant soil by *** sum,biochar promoted the growth of plants,improved the replant soil environment,and alleviated apple replant disease.

关键词： Biochar Fusarium oxysporum Apple replant disease Soil environment

Chemodivergent Synthesis of Benzofurans and 2,3-Dihydrobenzofurans via Tandem Oxidative Annulation of Enaminones and Salicylaldehydes

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Chinese Journal of Chemistry 2024年第15期42卷 1727-1733页

作者： Xiyan Duan Hui Li Junqi Wang Kun Liu Meixin Shi Weidong Lian ran chen Pu Liu School of Chemistry&Chemical Engineering Henan University of Science and TechnologyLuoyangHenan 471003China

Chemodivergent synthesis of benzofurans and 2,3-dihydrobenzofurans has been *** a reaction system consisting of DBDMH and K_(2)CO_(3) as promotors,controlled conditions enabled the formation of two sets of valuable heterocycles from the tandem transformation of enaminones and *** key to success was the identification of the reaction parameters,in which the imine intermediate which was formed by transient halogenation coupling and substitution processes underwent either aldol condensation/annulation or imine hydrolysis/aldol *** additives NH_(4)Cl or Fe_(2)(SO_(4))_(3) controlled the unique selectivity of this reaction.A broad substrate scope of enaminones and salicylaldehydes has been employed in this reaction,demonstrating excellent functional group tolerance and versatility.

关键词： Cross-coupling Umpolung Domino reactions Enaminone Benzofurans 2,3-Dihydrobenzofurans

Impact of fluorine on crystal-melt separation in high-silica magma: Insights from muscovite in the Ramba leucogranite of Tethyan Himalaya

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Journal of Earth Science 2024年

作者： Li-ran chen Wang-Chun Xu Lian-Xun Wang Hong-Fei Zhang Wuhan State Key Laboratory of Geological Processes and Mineral Resources， and School of Earth Sciences， China University of Geosciences

The process of crystal-melt separation in the high-silica magmatic mush is still a subject of debate. To explore the process， we conducted a detailed study of Late Miocene leucogranites (SiO2＞70 wt.%) in the Ramba Dome of the Tethyan Himalaya， focusing on the genesis and fluorine content of muscovite. The Ramba leucogranites consist of two-mica granite with minor garnet-bearing granite. Large and euhedral muscovites are found in both types of granite exhibiting different geochemical features. The muscovites from the two-mica granites exhibit lower F (mean value: ～0.41–0.43 wt.%)， FeO (mean value: ～1.75–1.81 wt.%)， but higher TiO2(mean value: ～0.61–0.73 wt.%) contents compared to those from the garnet-bearing granites (mean F value: ～0.72%; mean FeO value: 2.48 wt.%; mean TiO2value: ～0.23 wt.%). According to geochemical criteria， we categorized the muscovites from the two-mica granite as two groups: (1) crystallized from the early magma， and (2) formed from interstitial residual melt. In comparison， the muscovite from the garnet-bearing granite was likely crystallized from residual melt extracted from the same magmatic reservoir which underwent a higher degree of evolution. Accordingly， the two-mica granite represents the residual crystal mush consisting of early crystals crystallized from magma and trapped interstitial residual melt， while the garnet-bearing granite represents the aggregation of extracted residual melt. We examined the possibility of crystal-melt separation by estimating the variation of fluorine content and viscosity between the early magma and residual melt. Our results indicate a notable disparity in fluorine content between the residual melt (mean value: ～4364 ppm) and the early magma (mean value: ～2033 ppm). As a result， the estimated viscosity experiences a reduction from 106.52Pa s for the early magma to 105.87Pa s for the residual melt. The fluorine enrichment could have played a critical role in decreasing melt viscosity and initiating crys

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Controlling hydrogenation of C=C and C=O bonds in cinnamaldehyde using Pt_(1)/Ni and Pt_(1)/Co single-atom alloy catalysts

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Rare Metals 2024年第6期43卷 2859-2868页

作者： Huan-Shi Lan Yi-Da Yang Qing-Di Sun Hao Zhang Ying Zhang Qian He ran chen Guo-Yi Bai Xiao-Hui He Hong-Bing Ji School of Chemistry and Chemical Engineering Guangxi UniversityNanning 530004China Key Laboratory of Bioinorganicand Synthetic Chemistry of Ministry of Education Fine Chemical Industry Research InstituteSchool of ChemistryIGCMESun Yat-sen UniversityGuangzhou510275China UBFC CNRSENSMMFEMTO-ST Institute25030 Besancon CEDEXFrance College of Chemistry and Materials Science Hebei UniversityBaoding 071002China State Key Laboratory Breeding Base of Green-Chemical Synthesis Technology Institute of Green Petroleum Processing and Light Hydrocarbon ConversionCollege of Chemical EngineeringZhejiang University of TechnologyHangzhou 310014China

Selective hydrogenation of C=C and C=O bonds in cinnamaldehyde(CAL)to produce desired products is a challenging task due to the complex conjugate system of the two unsaturated functional *** this study,a simple ball milling method is presented for synthesizing Pt-based single-atom alloy catalysts(SAAs)that can function as a control switch for the selective hydrogenation of CAL into highly valuable products.

关键词： alloy hydrogenation conjugate

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深度伪造涉性信息的刑法规制

法学 2024年第3期 76-90页

作者：陈冉北京理工大学法学院

面对“深度伪造”技术在信息制作上高度的以假乱真可能以及在色情领域的广泛存在,有必要明确刑法在深度伪造涉性信息规制上的立足点,将深度伪造涉性信息规制定位在“真实的性隐私保护”而非对“虚假信息”的打击。在信息流动的产业化背... 详细信息

面对“深度伪造”技术在信息制作上高度的以假乱真可能以及在色情领域的广泛存在,有必要明确刑法在深度伪造涉性信息规制上的立足点,将深度伪造涉性信息规制定位在“真实的性隐私保护”而非对“虚假信息”的打击。在信息流动的产业化背景下,网络与信息所形成的新秩序对传统刑法在隐私保护上构成挑战,现行刑法过于倚重前端预防的打击不力。在深度伪造治理公、私法融合的趋势下,深度伪造涉性信息犯罪规制范式必须转型,要从性隐私保护和信息规制两个层面对涉性信息进行检视,彰显“性隐私”的独立保护地位,肯定现实与虚拟交互中“性”利益保护的适度远程化,以“场景化”构建个人信息违法行为的刑法规制路径。同时,在深度伪造涉性信息制作、传播主体刑事责任的认定上,考虑涉性信息参与各方的风险防御可能,在性隐私保护上应当合理对伪造者、网络服务提供者以及受害人进行风险分配,以“合规”划定网络服务提供者的刑事责任边界;考虑个人信息主体在隐私保护上的同意“受限”,立法和司法应当避免单纯根据受害人的同意和创作者的“标识”对涉性信息制作和传播者以及平台等风险创设者进行免责处理。

关键词：深度伪造涉性信息人格权性隐私规制范式

现代汉语中数量名回指语的指称性质与回指确认方式

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语言教学与研究 2024年第1期 59-68页

作者：冉晨西南大学文学院 400715

现代汉语中,形式上无定的数量名短语也可用于回指。根据具体语用功能,数量名回指语可分为普通回指、内涵凸显型回指和数量凸显型回指。在不同回指用法下,数量名回指语在构成成分、句法位置和适用语境上表现出显著的内部差异。这些内部... 详细信息

现代汉语中,形式上无定的数量名短语也可用于回指。根据具体语用功能,数量名回指语可分为普通回指、内涵凸显型回指和数量凸显型回指。在不同回指用法下,数量名回指语在构成成分、句法位置和适用语境上表现出显著的内部差异。这些内部差异揭示出数量名回指语实际包含定指和不定指两种不同指称性质,且通过不同的方式实现回指确认。定指数量名回指语可实现普通回指和内涵凸显型回指用法,通过数量信息和名词属性与工作记忆中的已知对象进行匹配建立同指关系。不定指数量名回指语可实现内涵凸显型回指和数量凸显型回指,它们在话语中“伪装”为新信息,其与已知对象的同指关系为“会话含义”,需要听话人根据语境信息推理得出。

关键词：回指数量名 “一量名” 指称性质会话含义

DNA vaccine prime and replicating vaccinia vaccine boost induce robust humoral and cellular immune responses against MERS-CoV in mice

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Virologica Sinica 2024年第3期39卷 490-500页

作者： Xiuli Shen Shuhui Wang Yanling Hao Yuyu Fu Li Ren Dan Li Wenqi Tang Jing Li ran chen Meiling Zhu Shuo Wang Ying Liu Yiming Shao National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases National Center for AIDS/STD Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China Changping Laboratory Yard 28Science Park RoadChangping DistrictBeijing 102206China State Key Laboratory for Diagnosis and Treatment of Infectious Diseases National Clinical Research Center for Infectious DiseasesCollaborative Innovation Center for Diagnosis and Treatment of Infectious DiseasesThe First Affiliated HospitalSchool of MedicineZhejiang UniversityHangzhou 310003China

As of December 2022,2603 laboratory-identified Middle East respiratory syndrome coronavirus(MERS-CoV)infections and 935 associated deaths,with a mortality rate of 36%,had been reported to the World Health Organization(WHO).However,there are still no vaccines for MERS-CoV,which makes the prevention and control of MERS-CoV *** this study,we generated two DNA vaccine candidates by integrating MERS-CoV Spike(S)gene into a replicating Vaccinia Tian Tan(VTT)*** to homologous immunization with either vaccine,mice immunized with DNA vaccine prime and VTT vaccine boost exhibited much stronger and durable humoral and cellular immune *** immunized mice produced robust binding antibodies and broad neutralizing antibodies against the EMC2012,England1 and KNIH strains of ***-Boost immunization also induced strong MERS-S specific T cells responses,with high memory and poly-functional(CD107a-IFN-γ-TNF-α)effector CD8t T *** conclusion,the research demonstrated that DNA-Prime/VTT-Boost strategy could elicit robust and balanced humoral and cellular immune responses against *** study not only provides a promising set of MERS-CoV vaccine candidates,but also proposes a heterologous sequential immunization strategy worthy of further development.

关键词： MERS-CoV VTT vaccine DNA vaccine Humoral and cellular immune responses Prime/boost strategy

Analysis of Phenotypes Associated with Deficiency of PAX6 Haplotypes in Chinese Aniridia Families

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Current Medical Science 2024年第4期44卷 820-826页

作者： Xiao-lu HAO ran chen Wei LIU Bao-ke HOU Ling-hui QU Zhao-hui LI Da-jiang WANG Xin JIN Hou-bin HUANG Senior Department of Opthalmology the Third Medical Center of Chinese PLA General HospitalBeijing100039China Bolin Eye Care Group Beijing100098China Department of Ophthalmology Hainan Hospital of Chinese PLA General HospitalSanya572000China Department of Ophthalmology the 74th Army Group HospitalGuangzhou510318China

Objective To examine the clinical phenotype and genetic deficiencies present in Chinese aniridia families with PAX6 haplotype *** A comprehensive questionnaire and ophthalmological assessments were administered to both affected patients and unaffected *** clinical feature analysis included the evaluation of visual acuity,intraocular pressure,slit-lamp anterior segment examination,fundus photography,and spectral domain optical coherence *** identify the mutation responsible for aniridia,targeted next-generation sequencing was used as a beneficial *** A total of 4 mutations were identified,consisting of two novel frameshift mutations(c.314delA,p.K105Sfs*33 and c.838_845dup AACACACC,p.S283Tfs*85),along with two recurring nonsense mutations(c.307C>T,p.R103X and c.619A>T,p.K207*).Complete iris absence,macular foveal hypoplasia,and nystagmus were consistent in these PAX6 haplotype-deficient Chinese aniridia families,while corneal lesions,cataracts,and glaucoma exhibited heterogeneity both among the families and within the same *** In our study,two novel PAX6 mutations associated with aniridia were identified in Chinese families,which expanded the phenotypic and genotypic spectrum of PAX6 *** also analyzed the clinical characteristics of PAX6 haplotype deficiency in Chinese aniridia families.

关键词： aniridia PAX6 mutation haplotype deficiency phenotype genotype

Characteristics and demographic factors of traditional Chinese medicine constitution types among elderly individuals in China:A national multistage cluster random study Author links open overlay panel

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Journal of Traditional Chinese Medical Sciences 2024年第3期11卷 257-263页

作者： Jing Xia Minghua Bai Huirong Song Houqin Li Dayan Zhang Mary Y.Jiang ran chen Feiyu He cheng Ni Center for Studies in Constitution and Reproductive Sciences of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing 100029China National Institute of TCM Constitution and Preventive Medicine Beijing University of Chinese MedicineBeijing 100029China Huangsi Comprehensive Outpatient Department Beijing Tongrentang Healthcare Industry Investment Group CompanyBeijing 100032China Zhangjiakou Second Traditional Chinese Medicine Hospital Zhangjiakou 076250China Faculty of Medicine The Chinese University of Hong KongHong Kong 999077China

Objective To reveal the distribution characteristics and demographic factors of traditional Chinese medicine(TCM)constitution among elderly individuals in *** Elderly individuals from seven regions in China were selected as samples in this study using a multistage cluster random sampling *** basic information questionnaire and Constitution in Chinese Medicine Questionnaire(Elderly Edition)were *** statistical analysis,chi-squared tests,and binary logistic regression analysis were *** The single balanced constitution(BC)accounted for 23.9%.The results of the major TCM constitution types showed that BC(43.2%)accounted for the largest proportion and unbalanced constitutions ranged from 0.9%to 15.7%.East China region(odds ratio[OR]=2.097;95%confidence interval[CI],1.912 to 2.301),married status(OR=1.341;95%CI,1.235 to 1.457),and managers(OR=1.254;95%CI,1.044 to 1.505)were significantly associated with ***>70 years was associated with qi-deficiency constitution and blood stasis constitution(BSC).Female sex was significantly associated with yang-deficiency constitution(OR=1.646;95%CI,1.52 to 1.782).Southwest region was significantly associated with phlegm-dampness constitution(OR=1.809;95%CI,1.569 to 2.086).North China region was significantly associated with inherited special constitution(OR=2.521;95%CI,1.569 to 4.05).South China region(OR=2.741;95%CI,1.997 to 1.3.763),Central China region(OR=8.889;95%CI,6.676 to 11.835),senior middle school education(OR=2.442;95%CI,1.932 to 3.088),and managers(OR=1.804;95%CI,1.21 to 2.69)were significantly associated with *** This study defined the distribution characteristics and demographic factors of TCM constitution in the elderly *** and improving unbalanced constitutions,which are correlated with diseases,can help promote healthy aging through the scientific management of these demographic factors.

关键词： Constitution in Chinese Medicine Questionnaire(Elderly Edition) Body constitution Multistage cluster random sampling Demographic factors Elderly individuals