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Effects of moringa oleifera aqueous extract on the growth performance,blood characteristics,and histological features of gills and livers in Nile tilapia

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Aquaculture and Fisheries 2024年第1期9卷 85-92页

作者： mahamoud A.Emam ramy m.shourbela Waleed N.El-Hawarry Seham Y.Abo-Kora Fatma Abdel-monem Gad Ashraf m.Abd El-latif mahmoud A.O.Dawood Histology Department Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Department of Animal Husbandry and Animal Wealth Development Faculty of Veterinary MedicineAlexandria UniversityAlexandria22758Egypt Pharmacology Department Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Clinical Pathology Department Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Department of Aquatic Animal Diseases and management Faculty of Veterinary MedicineBenha UniversityBenha13511Egypt Animal Production Department Faculty of AgricultureKafrelsheikh UniversityKafr El-Sheikh33511Egypt The Center for Applied Research on the Environment and Sustainability The American University in CairoCairo11835Egypt

moringa oleifera is well known as a highly nutritious plant and a water purifier in fish *** fish has many impressive qualities making them very suitable for ***,this study aimed to evaluate the effect of supplementation of moringa oleifera aqueous extract(mOAE)at varying concentrations(0,100,200,and 400 mg/kg diet for 90 days)on growth performance,hematological,and some biochemical parameters of Nile ***,histological changes and immunohistochemical expression of caspase 3 in gills and livers were *** enhancements(Pmoglobin,packed cell volume,white blood cells,and total serum protein were observed in fish fed 200 mg mOAE/kg diet compared with other ***,a significant reduction(Pmg mOAE/kg diet revealed disturbance in the corresponding *** histological degenerative changes were detected in the gills and liver of fish fed 400 mg mOAE/kg *** comparison,fish fed 200 mg mOAE/kg diet showed the best histo-architectures of these organs compared with other *** immune expressions of caspase 3 were determined where gills and liver of fish fed 400 mg mOAE/kg diet revealed extensive number of positive caspase 3 cells indicating severe apoptotic ***,a dietary mOAE at 200 mg/kg diet is recommended to improve the growth performance,hematological parameters,liver and kidney functions in Nile ***,caution must be considered when using mOAE at a concentration over 200 mg/kg diet.

关键词： Growth performance Liver Gills moringa oleifera Nile tilapia

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mechanism and technological evaluation of biopeptidal-based emulsions

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Food Bioscience 2022年第3期47卷 81-90页

作者： Tolulope Joshua Ashaolu ramy m.Khoder mohammed Saeed Alkaltham Asad Nawaz Noman Walayat muhammad Umair Ibrahim Khalifa Institute of Research and Development Duy Tan UniversityDa Nang550000Viet Nam Faculty of Environmental and Chemical Engineering Duy Tan UniversityDa Nang550000Viet Nam College of Food Science and Technology Huazhong Agricultural UniversityWuhanHubei Province430070PR China Department of Food Science & Nutrition College of Food and Agricultural SciencesKing Saud UniversityRiyadhSaudi Arabia Shenzhen Key Laboratory of marine microbiome Engineering Institute for Advanced StudyShenzhen UniversityShenzhen518060China College of Food Science and Technology Zhejiang University of TechnologyHangzhou310014China Department of Food Science and Engineering College of Chemistry and Environmental EngineeringShenzhen UniversityShenzhen518060GuangdongPR China Food Technology Department Faculty of Agriculture13736MoshtohorBenha UniversityEgypt

Both natural and synthetic peptides are not only biologically important,continuous research and comprehension of these short protein fragments show that they also have multifarious potentials in food manufacturing,namely emulsion-based *** emulsions may basically be oil-in-water or water-in-oil,as well as temporary,semi-permanent,or permanent in a continuous phase that suspends the droplets of the other elements used in food and pharmaceutical industries to formulate products such as gels,creams,ointments,and *** this review,the classification,preparation,and identification of peptides were described,followed by peptide-based emulsion properties and their relationship with regards to stability,structure,solubility,hydrophobicity,foaming,and water holding *** then dovetailed into the release rate and gastric stability of encapsulated peptides in the human digestive system,before exploring further needs and *** is desired that more studies be conducted to define the impact of carrier ingredients selection,encapsulation and processing techniques,environment,and peptides chemistry on peptide-based emulsions to attain high efficacy.

关键词： Peptides Emulsions Physicochemical properties Bioactivity Gastrointestinal stability

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mid-term results of sub-trochanteric valgus osteotomy for symptomatic late stages Legg-Calvé-Perthes disease

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World Journal of Orthopedics 2023年第5期14卷 328-339页

作者： Khaled m Emara ramy Ahmed Diab Ahmed K Emara mohamed Eissa mostafa Gemeah Shady Abdelghaffar mahmoud Department of Orthopedic Surgery Ain Shams UniversityCairo 11591Egypt Department of Orthopedic Surgery Cleveland Clinic FoundationClevelandOH 9500United States Health Care Innovation Program Arizona State UniversityTempeAZ 85287United States

BACKGROUND The treatment of late stages of Legg-Calvé-Perthes disease(LCPD)is *** the concept of femoral head containment is a well-established technique of treatment,its use remains debatable in the late stages of the disease,as it does not improve symptoms in terms of limb length discrepancy and *** To assess the results of subtrochanteric valgus osteotomy in symptomatic patients with late-stage Perthes *** From 2000 to 2007,36 symptomatic patients with late stage of Perthes disease were surgically treated with subtrochanteric valgus osteotomy and followed-up for 8 to 11 years using the IOWA score and range of motion(ROm)*** mose classification was also assessed at the last follow-up to reflect possible *** patients were 8 years old or older at the time of surgery,in the post-fragmentation stage,and complaining of pain,limited ROm,Trendelenburg gait,and/or abductor *** The preoperative IOWA score(average:53.3)markedly improved at the 1-year post follow-up period(average:85.41)and then slightly improved at the last follow-up(average:89.4)(P valuem improved,with internal rotation increased on average by 22°(from 10°preoperatively to 32°postoperatively)and abduction increased on average by 15.9°(from 25°preoperatively to 41°postoperatively).The mean mose deviation of femoral heads was 4.1 mm at the end of the follow-up *** tests used were the paired t-test and Pearson correlation test,where the level of significance was a P value less than *** Subtrochanteric valgus osteotomy can be a good option for symptomatic relief in patients with late-stage of LCPD.

关键词： Legg-Calvé-Perthes disease Femoral head avascular necrosis Valgus osteotomy Deformity correction Post fragmentation stage Late stage Perthes

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Pathways to Psychiatry Care among Children with mental Health Problems

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International Journal of mental Health Promotion 2022年第4期24卷 539-550页

作者： Hisham A.ramy Soheir H.Elghonemy Nesreen m.mohsen Safi m.Nagib mohamed Y.mohamed Neuropsychiatry Department Ain Shams UniversityCairo11566Egypt

many children with mental health problems in Egypt,as in many other countries,do not receive the help they *** the pathways of care is crucial for the early detection and treatment of these *** study examined referral patterns and the duration of untreated psychiatric illness of 350 children attending two urban clinical settings in *** were made using the Kiddie Schedule for Affective Disorder and Schizophrenia for School-aged children present and lifetime(K-SADS-PL),Child behavior checklist(CBCL,)and the Stanford-Binet Intelligence *** 46.3%,the most distressing symptom was behavioral problems.A delay in seeking psychiatric help was *** family history,and lower socioeconomic class were asso-ciated with delays in psychiatric *** 39.7%of patients,theﬁrst contact was with a *** children were referred by *** programs are needed to increase knowledge about and to decrease the duration of untreated illness.

关键词： Pathways to care children service mental illness referral

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Symmetry in optics and photonics:a group theory approach

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Science Bulletin 2018年第4期63卷 244-251页

作者： B.m.Rodriguez-Lara ramy EI-Ganainy Julio Guerrero Tecnologico de monterrey.Escuela de Ingenieria y Ciencias Monterrey 64849Mexico Instituto Nacional de Astrofisica Optica y Electr6nicaPueblaCP 72840Mexico Department of Physics and Hexes Center for Quantum Phenomena Michigan Technological UniversityHoughton.MI 49931USA Departamento de matematicas Facultad de Ciendas Experimentales y de la SaludCampus Las LagunillasUniversidad de Jaen23071JaenSpain Departamento de Ingenierfa y Tecnologia de Computadores Facultad de lnformdticaCampus EspinardoUnivesidad de Murcia30100 MurciaSpain

Group theory(GT) provides a rigorous framework for studying symmetries in various disciplines in physics ranging from quantum field theories and the standard model to fluid mechanics and chaos theory. To date, the application of such a powerful tool in optical physics remains limited. Over the past few years however, several quantum-inspired symmetry principles(such as parity-time invariance and supersymmetry) have been introduced in optics and photonics for the first time. Despite the intense activities in these new research directions, only few works utilized the power of group theory. motivated by this status quo, here we present a brief overview of the application of GT in optics, deliberately choosing examples that illustrate the power of this tool in both continuous and discrete setups. We hope that this review will stimulate further research that exploits the full potential of GT for investigating various symmetry paradigms in optics, eventually leading to new photonic devices.

关键词：对称原则光学调查混乱理论液体力学标准模型光物理工具时间

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Determinants of Schistosoma mansoni transmission in hotspots at the late stage of elimination in Egypt

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Infectious Diseases of Poverty 2022年第5期11卷 95-96页

作者： ramy mohamed Ghazy Walid Ismail Ellakany mai m.Badr Nehad E.m.Taktak Heba Elhadad Sarah mAbdo Ayat Hagag Abdel Rahman Hussein mohamed mostafa Tahoun 不详 Department of Tropical medicine Faculty of MedicineAlexandria UniversityAlexandriaEgypt

Background In certain settings,the prevalence and severity of schistosoma infection do not lessen despite repeated rounds of preventative chemotherapy;these areas are known as *** study aimed to investigate the role of human practices,besides environmental and malacological factors,in the maintenance of the Schistosoma mansoni infection transmission chain in hotspot areas in *** This cross-sectional study was conducted between July and November 2019 in Kafr El-Sheikh Governorate,Egypt.A pre-designed structured interviewing questionnaire was used to collect humanitarian *** samples were collected from children aged 6–15 years on three successive days and examined using the Kato-Katz ***,water and snail samples were taken from watercourses surrounding *** were identified based on their shell morphology and structure and tested for cercaria *** samples were analyzed for their physicochemical and biological *** A total of 2259 fecal samples(1113 in summer and 1146 in fall)were collected from 861 *** 46.9%of the participants were males,and 31.8%were aged 6–10 *** prevalence of *** infection was higher during the summer than during the fall(19.1%vs 7.2%,respectively,Pmoderate,and heavy)during summer versus fall was(93.55 vs 89.38%,6.45 vs 8.85%,and 0.00%vs 1.77%),respectively(Pman infection was observed among males than females[OR=1.63,95%confidence interval(CI):1.10–2.40,P=0.015],children aged 11–15 years than among their counterparts aged 6–10 years(OR=2.96,95%CI:1.72–5.06,Pmothers with a low level of education(OR=3.33,95%CI:1.70–6.52,Pmain identified risk factors were contacting the main body of water-canal for washing clothes(OR=1.81,95%CI:1.12–2.49,P=0.015),land irrigation(OR=2.56,95%CI:1.32–4.96,P=0.004),water collection(OR=2.94,95%CI:1.82–4.73,P<0.001),bathing(

关键词： Schistosoma mansoni Praziquantel Biomphalaria alexandrina Community engagement Transmission cycle Neglected tropical diseases

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Numerical Algorithm for Solving multi-Pantograph Delay Equations on the Half-line Using Jacobi Rational Functions with Convergence Analysis

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Acta mathematicae Applicatae Sinica 2017年第2期33卷 297-310页

作者： Eid H. DOHA Ali H. BHRAWY ramy m. HAFEZ Department of mathematics Faculty of Science Cairo University Giza Egypt Department of mathematics Faculty of Science King Abdulaziz University Jeddah Saudi Arabia Department of mathematics Faculty of Science Beni-Suef University Beni-Suef Egypt Department of mathematics Alwagjh University College University of Tabuk Tabuk Saudi Arabia Department of Basic Science Institute of Information Technology Modern Academy Cairo Egypt

A new spectral Jacobi rational-Gauss collocation （JRC） method is proposed for solving the multi- pantograph delay differential equations on the half-line. The method is based on Jacobi rational functions and Gauss quadrature integration formula. The main idea for obtaining a semi-analytical solution for these equations is essentially developed by reducing the pantograph equations with their initial conditions to systems of algebraic equations in the unknown expansion coefficients. The convergence analysis of the method is analyzed. The method possesses the spectral accuracy. Numerical results indicating the high accuracy and effectiveness of this algorithm are presented. Indeed, the present method is compared favorably with other methods.

关键词： multi-pantograph equation delay equation collocation method Jacobi-Gauss quadrature Jacobirational functions convergence analysis

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The Value of Serum midKine as a marker of Hepatocellular Carcinoma on Top of Hepatitis C Virus Related Cirrhosis

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Journal of Biosciences and medicines 2022年第4期10卷 37-47页

作者： Ayman menessy Ehab Fouda Salah Aref ramy Agwa Internal medicine Department Faculty of Medicine Mansoura University Mansoura Egypt m. B. B. Ch Faculty of Medicine Mansoura University Mansoura Egypt Clinical Pathology Department Faculty of Medicine Mansoura University Mansoura Egypt

Background: Hepatocellular carcinoma (HCC) is characterized by the deficiency of specific symptoms in the early stages of the disease and a poor prognosis. Biomarkers that have the diagnostic ability to distinguish between inflammation, cirrhosis, and HCC are needed for early case detection. midKine (mK) is overexpressed in many malignancies, including hepatocellular carcinoma, gastric carcinoma, colon carcinoma, lung carcinoma, urinary bladder carcinoma and prostate carcinoma. Objective: The objective is to evaluate serum midKine as a marker of HCC in HCV-related liver cirrhosis. Patients and methods: This study included 50 patients with HCC (on top of hepatitis C virus-related cirrhosis), 20 cirrhotic patients due to chronic HCV infection, and 10 normal subjects as a control group. History, examination, and laboratory investigations were performed on all subjects in the three groups including mK and Alpha fetoprotein (AFP) serum levels. Results: Serum levels of AFP and mK were higher in the HCC group than in the other study groups (P Conclusion: midKine is a novel sensitive biomarker that could be used for early detection of HCC and has a high significance in differentiation between cirrhosis and HCC cases. midKine levels are correlated with HCC stages and sizes.

关键词： midKine Hepatocellular Carcinoma Alpha-Fetoprotein Chronic Hepatitis C

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Novel aspects for thermal stability studies and shelf life assessment of modified double-base propellants

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Defence Technology（防务技术） 2019年第3期15卷 300-305页

作者： Sherif Elbasuney Ashraf.m. A. Elghafour mostafa Radwan Ahmed Fahd Hosam mostafa ramy Sadek Amr motaz School of Chemical Engineering Military Technical College Kobry El-Kobba Cairo Egypt British University in Egypt Elshrouk city Cairo Egypt

modified DB propellants, based on energetic nitramine(RDX) were manufactured by solventless extrusion process. Thermal stability and shelf life assessment of modified DB propellant were investigated. Shelf life assessment was evaluated using Van’t Hoff’s formula and artificial aging at 70℃ up to120 days. Quantification of total heat released and heat flow with aging time was conducted using differential scanning calorimetry(DSC) and thermal activity monitoring(TAmIII) respectively. modified DB formulation based on 20 wt % RDX demonstrated enhanced thermal stability in terms of controlled heat flow, and slow decomposition reactions at elevated temperature. This formulation demonstrated extended service life up to 56 years compared with reference formulation. These novel finding was ascribed to the high thermal stability of RDX and its compatibility with DB constituents. This manuscript shaded the light on novel and effective approach for thermal stability via monitoring thermal activity with aging.

关键词： Double-base propellant Thermal stability Artificial aging Shelf-life assessment

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Assessment of lnc RNA GAS5, lnc RNA HEIH, lnc RNA BISPR and its m RNA BST2 as serum innovative non-invasive biomarkers: Recent insights into Egyptian patients with hepatitis C virus type 4

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World Journal of Gastroenterology 2020年第2期26卷 168-183页

作者： Nourhan m El Samaloty marwa I Shabayek ramy S Ghait Shohda A El-maraghy Sherine m Rizk maha m El-Sawalhi Biochemistry Section PharmacologyToxicology and Biochemistry DepartmentFaculty of Pharmaceutical Sciences and Pharmaceutical IndustriesFuture UniversityCairo 11795Egypt Internal medicine Gastroenterology and Hepatology DepartmentFaculty of MedicineAin Shams UniversityCairo 11566Egypt Biochemistry Department Faculty of PharmacyCairo UniversityCairo 11562Egypt

BACKGROUND Hepatitis C virus(HCV)infection and its consequent complications are undeniably a public health burden worldwide,particularly in *** evidence suggests that many lncRNAs have relevant roles in viral infections and antiviral *** To investigate the expression profiles of circulating lncRNAGAS5,lncRNAHEIH,lncRNABISPR and mRNABST2 in naïve,treated and relapsed HCV Egyptian patients,to elucidate relation to HCV infection and their efficacy as innovative biomarkers for the diagnosis and prognosis of HCV *** One hundred and thirty HCV-infected Egyptian patients and 20 healthy controls were included in this *** lncRNAs and mRNABST2 were measured using quantitative real-time polymerase chain reaction(qRT-PCR).RESULTS Our results indicated that serum lncRNAGAS5 and LncRNABISPR were upregulated,whereas mRNA BST2 and LncRNA HEIH were downregulated in naïve *** contrast,HCV patients treated with sofosbuvir and simeprevir;with sofosbuvir and daclatasvir;or with sofosbuvir,daclatasvir and ribavirin exhibited lower levels of lncRNAGAS5 and lncRNABISPR with higher mRNABST2 compared to naïve ***,patients relapsed from sofosbuvir and simeprevir showed higher levels of these lncRNAs with lower mRNABST2 compared to treated ***5 and lncRNABISPR were positively correlated with viral load and ALT at PmRNABST2 was negatively correlated with viral load at Pment in HCV pathogenesis or antiviral response and highlights their promising roles in diagnosis and prognosis of HCV.

关键词： lncRNA GAS5 lncRNA BISPR mRNA BST2 lncRNA HEIH Hepatitis C Biomarkers

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