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Unidirectional reflection from an integrated“taiji”microresonator

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Photonics Research 2020年第8期8卷 1333-1341页

作者： A.CALABRESE F.ramiro-MANZANO H.M.PRICE S.BIASI M.BERNARD M.GHULINYAN I.CARUSOTTO L.PAVESI Laboratoire de Physique de l’Ecole Normale Superieure ENSParis Sciences et LettresCNRSUniversitéde Paris75005 ParisFrance Instituto de Tecnologı´a Quı´mica(CSIC-UPV).Av.de los Naranjos 46022 ValenciaSpain School of Physics and Astronomy University of BirminghamEdgbastonBirmingham B152TTUK Nanoscience Laboratory Dipartimento di FisicaUniversity of TrentoVia Sommarive 1438123 Povo(TN)Italy Centre for Materials and Microsystems Fondazione Bruno KesslerVia Sommarive 1838123 Povo(TN)Italy INO-CNR BEC Center and Department of Physics University of TrentoVia Sommarive 1438123 PovoItaly

We study light transmission and reflection from an integrated microresonator device,formed by a circular microresonator coupled to a bus waveguide,with an embedded S-shaped additional crossover waveguide element that selectively couples counter-propagating modes in a propagation-direction-dependent *** overall shape of the device resembles a“taiji”symbol,hence its *** Lorentz reciprocity is preserved in transmission,the peculiar geometry allows us to exploit the non-Hermitian nature of the system to obtain high-contrast unidirectional reflection with negligible reflection for light incident in one direction and a significant reflection in the opposite direction.

关键词： hence negligible crossover

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墨西哥***私人俱乐部

现代装饰 2011年第9期 106-111页

作者： Emmanuel Picault Ludwig Godefroy ramiro Chaves 肖俊 Ludwig Godefroy设计公司

在墨西哥城的Roma区有一幢破旧不堪的房子，每当夜幕降临、华灯初上，这幢破败的房屋前便人头攒动，衣着光鲜、神采变奕的人们三五成群地纷纷踏入。这一神秘现象道出了房屋内在的玄机。事实上。这幢房屋原本属于墨西哥历史上一位有名的... 详细信息

在墨西哥城的Roma区有一幢破旧不堪的房子，每当夜幕降临、华灯初上，这幢破败的房屋前便人头攒动，衣着光鲜、神采变奕的人们三五成群地纷纷踏入。这一神秘现象道出了房屋内在的玄机。事实上。这幢房屋原本属于墨西哥历史上一位有名的革命家、哲学家及社会活动家——MNRoy．

关键词：墨西哥城俱乐部社会活动家神秘现象房屋哲学家房子

Estrus Synchronization and Artificial Insemination with Fresh and Chilled Semen in Assaf Ewes

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Agricultural Sciences 2018年第1期9卷 8-22页

作者： Raquel Fornazari óscar Mateus Teresa Correia Hélder Quintas Raimundo Maurício Anderclei Conradi Lucas Francisco Armindo álvaro ramiro Valentim Federal Technology University of Paraná Campus of Dois Vizinhos Dois Vizinhos Brasil Department of Animal Science Agrarian Superior School of Braganza Braganza Portugal Mountain Investigation Center Polytechnic Institute of Braganza Braganza Portugal Polytechnic Superior Institute of Kwanza Sul Sumbe Angola

This paper aims to study the efficiency of two short-term progestagen (FGA vs. MAP) + eCG treatments in estrus synchronization and artificial insemination (AI) with fresh or chilled semen in Assaf ewes fertility rate. All ewes received a subcutaneous implant of exogenous melatonin 45 days before been treated with short-term progestagens + eCG. By June 1st, ewes were divided in two groups: half was treated with an intravaginal sponge impregnated with 20 mg of FGA and the other half with an intravaginal sponge impregnated with 60 mg of MAP. Progestagen treatments lasted for 6 days. At sponge withdraw, all ewes were injected with 750 IU of eCG. Ovarian activity was assessed by plasmatic progesterone levels before and after progestagens + eCG treatment. Semen was collected by electro ejaculation and extended with Andromed? or OviXcell?. AI was performed 55 hours after eCG administration with fresh or chilled semen. During AI several factors were assessed: vagina mucosa color and lubrication, external cervical Os type, cervical mucous viscosity, semen deposition place and seminal cervix outflow. Semen was deposited as deep as possible without distress or trauma cervix mucosa. All Assaf ewes presented cyclic activity before progestagen + eCG treatments (2nd fortnight of May). Short-term progestagen + eCG treatments were equally efficient (100.0%). About 76.5% of Assaf ewes were pregnant 41 days after AI. Fertility rate was influenced by external Os type, semen deposition place and seminal cervix outflow. However, this rate was not conditioned by vaginal color or lubrication, cervical mucus viscosity, semen preservation technic and semen extender.

关键词： Sheep Assaf Estrus Synchronization Artificial Insemination

Thoracic Unilateral Spinal Cord Syndrome Following Neuraxial Anaesthesia for Periprosthetic Knee Fracture: A Case Report

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Open Journal of Anesthesiology 2019年第11期9卷 197-202页

作者： Nahir Chalup Torija Á lvaro ramiro Ruiz Rubén Rodriguez Salas Beatriz Fuentes Benito Marina Nevado Villafruela Manuel Cortés Guerrero Anaesthesia Critical Care Department and Pain Medicine Hospital Universitario 12 de Octubre Madrid Spain Hospital Universitario Fundación Alcorcón Alcorcón Spain Centro de Salud de Torrelodones Áreanoroeste Torrelodones Spain

Neuraxial anaesthesia is widely used in surgical procedures;overall, epidural and intrathecal techniques. Nevertheless, several outcomes should be considered. The incidence of neurologic complications after neuraxial anaesthesia is not perfectly clear (0% - 0.08%), although there are several described cases of spinal cord ischemia. We present a case of thoracic unilateral spinal cord syndrome following lumbar spinal anaesthesia for periprosthetic knee fracture. Our patient suffered monoparesis in her left lower limb as well as decreasing of muscle strength and loss of tendon reflexes. The MNR showed left hyperintense intra-cord images from T7 to T12 attributed to spinal cord oedema and a lineal hypointensity related to minimal haematic component. What made this case surprising was the fact that spinal anaesthesia was performed between L3 and L4 and the patient did not suffer paraesthesia associated with local anaesthetic injection. She was treated with glucocorticoids, gabapentin and amitriptyline. She also was checked by physical rehabilitators, neurologists and Pain Unit physicians. We have found another case reported in the literature about thoracic cord injury after lumbar spinal puncture. In this paper, we report possible aetiologies according to a review and neurological evolution of the patient seven months later.

关键词： Neuraxial Anaesthesia Regional Anaesthesia Neurologic Complications Spinal Cord Injury

Relationship of Polymorphisms of Glutathione S-Transferase GSTT1 and GSTM1 With the Response to Chemotherapy In Mexican Women with Advanced Breast Cancer

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Journal of Cancer Therapy 2011年第3期2卷 354-361页

作者： Odeth Soto-Quintana Paula Cabrera-Galeana Gabriel Téllez-Trevilla José Luis Barrera-Franco Alejandro Juárez-ramiro Julieta Castillo-Cadena 不详

Introduction: Breast cancer is a common disease diagnosed in Mexican women and the first leading cause of death [1]. Heterogeneity in patients’ response to treatment is consistently observed across populations. Glutathione S-transferases (GSTs) are involved in the metabolism of environmental carcinogens, reactive oxygen species and chemotherapeutic agents by catalyzing the glutathione with electrophilic compounds. The deletion of GSTT1 and GSTM1 genes result in loss of enzyme activity. A few studies evaluated the response to treatment and the polymorphisms of GSTT1 and GSTM1. The aim of this work is to make the association of the null polymorphisms of GSTT1 and GSTM1 with the response to chemotherapy basically doxorubicin and cyclophosphamide. Methods: The genotyping of thirty patients with breast cancer was made with the Polymerase chain reaction, to identify the polymorphisms of GSTT1 and GSTM1. We determine the status of Her-2 neu, estrogen and progesterone receptors, then the response to treatment was made with an ultrasound and pathological data. We made the association with the χi2 statistics using a p≤0.05. Results: Using the Sigma Stat 3.5 program and the chi-squared analysis, we do not observe a significant association with the GSTT1+/GSTM1+, GSTT1-/GSTM1+ and GSTT1-/GSTM1-polymorphisms and the better or worse response to cyclophosphamide and doxorubicin. With the Her-2 neu, estrogen and progesterone receptors status, we neither found an association with the response to the therapy. Conclusion: This study suggests that GSTT1 and GSTM1 polymorphisms have no statistical significance between the genotype of women with advanced breast cancer and the response to neoadjuvant chemotherapy, but we can see a clear tendency toward better response with the null genotype.

关键词： Breast Cancer GSTT1 GSTM1 Polymorphisms Chemotherapy Response

Cytotoxic Effect of Methanol Extracts and Partitions of Two Mexican Desert Plants against the Murine Lymphoma L5178Y-R

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American Journal of Plant Sciences 2016年第11期7卷 1521-1530页

作者： ramiro Quintanilla-Licea Ricardo Gomez-Flores Mario Ángel Samaniego-Escamilla Humberto Carlos Hernández-Martínez Patricia Tamez-Guerra Rolando Morado-Castillo Laboratorio de Fitoquímica Facultad de Ciencias Biológicas Universidad Autónoma de Nuevo León UANL San Nicolás de los Garza México Laboratorio de Inmunobiología y Virología Facultad de Ciencias Biológicas Universidad Autónoma de Nuevo León UANL San Nicolás de los Garza México

Pachycereus marginatus (DC.) Britton & Rose and Ibervillea sonorae (S. Watson) Greene have been used in the Mexican traditional medicine for the treatment of various diseases, including cancer. The present study aims to investigate the cytotoxic activity of these plants against a murine lymphoma. Soxhlet extraction of dried and powdered plant material was performed with methanol. Also, a further partitioning of these methanolic extracts with hexane and ethyl acetate was achieved. The in vitro cytotoxic activity against the murine lymphoma L5178Y-R cell line was assessed via the colorimetric MTT assay. The methanol extract from P. marginatus exhibited high cytotoxic activity (up to 94%) at concentrations ranging from 3.9 to 500 μg/mL;however, hexane and ethyl acetate partitions from this methanolic extract showed lower but significant (p < 0.05) concentration-dependent cytotoxicity (hexane partition up to 94% at 500 μg/mL;ethyl acetate partition up to 94% at 65.5 μg/mL). The methanolic extract and partitions derived from I. sonorae also showed significant (p < 0.05) and concentration-dependent cytotoxicity against L5178Y-R cells at concentrations ranging from 7.81 to 500 μg/mL (methanolic extract up to 63% at 500 μg/mL;hexane partition up to 76% at 250 μg/mL;ethyl acetate partition up to 73% at 500 μg/mL). These results demonstrate that the methanol extracts and partitions from P. marginatus and I. sonorae possess significant cytotoxic activity against the murine lymphoma L5178Y-R and validate the ethnobotanical use of these plants for the treatment of diseases consistent with cancer symptomatology. Previous scientific reports describe the isolation of isoquinoline alkaloids of P. marginatus as well as cucurbitacins from I. sonorae, phytochemicals that could be responsible for their observed cytotoxic activity in this research. The direct extraction with methanol of medicinal plants allows extracting of both high and low-polarity compounds, contrary to the simple ext

关键词： Anticancer Plants Cactaceae Cucurbitaceae Mexican Medicinal Plants Extracts Partitions

On the Seismic Resilience

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Journal of Geological Resource and Engineering 2019年第4期7卷 132-139页

作者： ramiro Sofronie Independent Technical Expert Bucharest 030823Romania

The paper deals with the self-defending capacity of buildings and structures against earthquakes. The idea of this conceptcomes from Hooke’s Law of elasticity published in 1678. The original deterministic concept was converted, with the aid of reliabilityanalysis, into a probalistic form. In this way seismic resilience covers a larger field of random phenomena and becomes directlyinvolved in more engineering applications.

关键词： Complementarity confidence durability elasticity jerk plausibility reliability

Non-Communicable Chronic Diseases and Structural Indicators in an Epidemiological Transition Country

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Open Journal of Epidemiology 2020年第1期10卷 32-42页

作者： Natalia Romero-Sandoval S. ramiro Canelos Héctor Javier Sánchez-Pérez Ricardo Romero Fernando Cornejo Miguel Martín-Mateo Escuela de Medicina Facultad de Ciencias Médicas de la Salud y de la Vida Universidad Internacional del Ecuador Quito Ecuador Grups de Reserca d’Amèrica i àfrica Llatines-GRAAL Cerdanyola del Vallés España Facultad de Ciencias Administrativas Universidad Internacional del Ecuador Quito Ecuador El Colegio de la Frontera Sur-ECOSUR San Cristóbal de Las Casas Chiapas México Instituto Geográfico Militar Seniergues E4-676 y Gral. Telmo Paz y Miño Quito Ecuador Facultad de Medicina Universidad Tecnológica Equinoccial Bourgeois Quito Ecuador Unidad de Bioestadística Facultad de Medicina Universidad Autónoma de Barcelona Cerdanyola del Vallés Barcelona Spain

Objective: To determine associations between standardized prevalence ratios of Metabolic Syndrome (MS), High Blood Pressure (HBP), and Obesity (O) with structural factors in ecuadorian population aged 20 to 59. Methods: An ecological study was conducted through data from the Ecuador’s National Health and Nutrition Survey 2013-2014, and National Census. Standardized prevalence ratio (SPR) variability was analyzed with Poisson multiple regression models (adjusted Relative Risk). Results: The SPR variability for the three diseases was associated with non-affiliation to social security, and inversely related to lower urbanization. HBP and O were associated with functional illiteracy and higher rates of primary care physicians/1000 inhabitants. HBP and MS were related to poor housing. Conclusions: Policies of non-communicable chronic diseases control in ecological transition countries need to take structural variations into account.

关键词： Chronic Illness Social Inequality Statistical Analysis Policy Process Ecuador

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墨西哥JULES鸡尾酒吧

现代装饰 2012年第6期 106-109页

作者： Emmanuel Picault Ludwig Godefroy ramiro Chaves 代照墨西哥Chic by Accident设计工作室

Jules鸡尾酒吧位于一家墨西哥酒吧的地下室内。以黑暗空间的模糊感为设计灵感，设计师塑造了现代鸡尾酒吧不能缺少的隐晦感觉，并且将这个项目的精髓定义为“局限带来的艺术”。

关键词：墨西哥酒吧鸡设计灵感暗空间设计师室内