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Neuroimmunology and Neuroinflammation 2017年第11期4卷 232-235页

作者： Bipin Kumar Chaurasia Narendra shaIike siIak Ram Chaudhary shamsuI AIam Dhiman Chowdhory KanakKanti Barua Ranjit Kumar Chaurasiya Raushan Kumar Chaurasia ramesh Kumar Chaurasia ToIga Dundar Department of Neurosurgery Bangabandhu Sheikh Mujib Medical UniversityShahbagDhaka1000Bangladesh Department of Emergency and Casualty Bhawani HospitalBirgunj44300Nepal Department of Nephrology Golden Hospital Pvt.Ltd.Hospital ChowkBiratnagar56613Nepal Department of Neurosurgery Bezmialem VakιfUniverstyItanbul34265Turkey

Intracranial lipomas are rare benign tumour that is slow growing, generally asymptomatic, most frequently located in the midline areas and are usually an incidental finding on imaging and therefore cases are not frequently reported. This study reports a case of a patient with quadrigeminal plate lipoma presenting with obstructive hydrocephalous and the 6th cranial nerve palsy that was successfully treated with ventriculo-peritoneal shunting without addressing the lesion.

关键词： Lipoma quadrigeminal plate the 6th cranial nerve palsy hydrocephalus

Hepatitis B virus subgenotype A1 predominates in liver disease patients from Kerala,India

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World Journal of Gastroenterology 2013年第48期19卷 9294-9306页

作者： Deepak Gopalakrishnan Mark Keyter Kotacherry Trivikrama shenoy Kondarappassery Balakumaran Leena Lakshmikanthan Thayumanavan varghese Thomas KR vinayakumar Charles Panackel Arun T Korah ramesh Nair Anna Kramvis Hepatitis virus Diversity Research Programme Department of Internal Medicine School of Clinical Medicine Faculty of Health Sciences University of the Witwatersrand Parktown Johannesburg 2193 South Africa Department of Gastroenterology Medical College Trivandrum 695011 India Population Health and Research Institute Trivandrum 695011 India Government Rajaji Hospital Madurai Medical College Madurai 625002 India Department of Gastroenterology Calicut Medical College PO Calicut 673008 India

AIM:To molecularly characterize hepatitis B virus(HBv)isolates from Kerala and to relate them to the clinical manifestation of ***:sera and clinical data were collected from91 patients diagnosed with chronic HBv infection and HBv-related hepatocellular carcinoma(HCC).HBv from44 HCC,22 cirrhotic and 25 chronic hepatitis patients were genotyped by sequencing of the complete s region or by restriction fragment length polymorphism *** basic core promoter/precore region was *** complete surface DNA sequences were assembled and aligned manually,and then compared with the sequences of HBv of genotypes(A-J)from *** evolutionary history was inferred using the Neighbor-Joining method and the evolutionary distances computed using the Kimura 2-parameter *** was performed using 1000 *** TaqMan Bs-1 probe was used to quantify HBv DNA at a lower detection limit of approximately20 IU/*** variables were compared using an independent student’s t ***χ2test or Fisher’s exact test was used to compare categorical *** differences were considered statistically significant at Pspective of disease status,the predominant genotype was A(72%);95%belonging to subgenotype A1,followed by genotypes D(27%)and C(1%).HCC patients infected with subgenotype A1were significantly younger than those infected with *** A1762T/G1764A was significantly associated with HCC in both genotypes A and *** G1862T was more frequent in subgenotype A1(Ps significantly associated with HBv from HCC *** C1766T/T1768A was significantly associated with genotype A(P=0.05)and HCC(P=0.03).The pres2start codon M1T/I mutation was unique to genotype A strains(15.6%)from all disease groups and occurred at a higher frequency in isolates from HCC patients(P=0.076).A higher frequency of pres deletion mutants(33.3%)was observed in genotype A from HC

关键词： Hepatocellular carcinoma Cirrhosis Chronic hepatitis Phylogenetic analysis Genotype India

Evaluation of Corrosion stability of Water soluble Epoxy-Ester Primer through Electrochemical studies

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A Prospective, Multicentric, Post Marketing surveillance to Evaluate Efficacy & safety of Ranitidine HCl (150 & 300 mg IR/CR) in Indian Patients with Gastroesophageal Reflux Disease (PROGRADE)

Materials sciences and Applications（材料科学与应用期刊） 2012年第6期

作者： Duraisamy ramesh Thiagarajan vasudevan

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Open Journal of Gastroenterology 2023年第7期13卷 237-249页

作者： Akash shukla Anil Kumar Awasthi ramesh Rao Dawesh Prakash Yadav Nilesh Nolkha Rajesh Pendlimari sanjiv Dua shrish Bhatnagar Ravindra Mote Ashish Birla Jay savai Kapil Mehta shashank salunke Department of Gastroenterology Gastro Universe Mumbai India Department of Medicine Ajanta Research Centre Ajanta Hospital & IVF Centre Lucknow India Departmentof Nephrology Sanjeevani Kidney Care Mumbai India Department of Gastroenterology Institute of Medical Sciences Banaras Hindu University Varanasi India Department of Rheumatology Wockhardt Hospitals Mumbai India Department of Gastroenterology Rajalakshmi Hospital and Research Center Bangalore India Department of General surgery SaiKripa Hospital Mumbai India Department of Gastroenterology Sparsh Child Care and Gastro Centre Lucknow India Department of Clinical Research Mediclin Clinical Research Mumbai India Department of Medical Affairs JB Chemicals & Pharmaceuticals Ltd. Mumbai India

Purpose: Ranitidine hydrochloride (HCl) remains an important medication for treating acid-peptic ailments such as Gastroesophageal reflux disease (GERD). The main objective of this Post Marketing surveillance (PMs) clinical study was to test the efficacy and safety of Ranitidine HCl in Indian patients suffering from GERD. Patients and Methods: Data of 2446 patients (1307 males;1121 females) from 21 centers across India were analyzed. Patients received either of the three treatments: Ranitidine HCl 150 mg twice a day (BID) (ARM-A), Ranitidine HCl 300 mg once daily (OD) or BID (ARM-B), and Ranitidine HCl 300 mg OD (ARM-C). Gastroesophageal Reflux Disease symptom Assessment scale (GsAs) score and Heartburn severity score were used to assess the drug’s efficacy. The adverse events reported by patients or investigators were analyzed to assess the safety profile of Ranitidine. Results: Of the 2446 subjects screened, 2428 were enrolled. There was a significant reduction in GsAs scores from baseline to the end of the study visit in all three ARMs. The GsAs scores reduced from 2.02 to 0.23 in ARM-A, 2.01 to 0.24 in ARM-B, and 2.07 to 0.26 in ARM-C patients. In ARM A, 72.82% had 24 hours heartburn-free days, and 66.89% had 7 consecutive heartburn-free days, which was more significant than the other two ARMs. 128 (5.27%) patients reported ADRs due to Ranitidine HCl at different doses. The most frequently reported ADR was constipation (17.18%), followed by oliguria (14.06%), cold (13.28%), and dysuria (12.5%). Of 128 ADRs, 113 (88.28%) were mild, and only 11 (8.59%) ADRs were related to the study drug. No severe ADRs were reported during the study. Conclusion: Ranitidine HCl 150/300 mg tablet was found to be an effective and safe H2-receptor antagonist for treating GERD in Indian Patients.

关键词： Ranitidine Hydrochloride GERD Heartburn H2-Receptor Antagonists

Magnetic Nano Cobalt Ferrite Catalyzed synthesis of 4H-Pyrano[3,2-h]quinoline Derivatives under Microwave Irradiation

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Green and sustainable Chemistry 2016年第2期6卷 101-109页

作者： swathi Bandaru Ravi K. Majji satyanarayana Bassa Pandu N. Chilla ramesh Yellapragada sruthi vasamsetty Rajendra K. Jeldi Raghu B. Korupolu Paul D. sanasi Department of Engineering Chemistry A. U. College of Engineering (A) Andhra University Visakhapatnam India

A microwave irradiated magnetically separable nano cobalt ferrite catalyzed green method for the synthesis of 4-phenyl-4H-pyrano[3,2-h]quinolin-2-amine and 2-amino-4-phenyl-4H-pyrano[3,2-h] quinoline-3-carbonitrile derivatives through cyclization of aromatic aldehyde, acetonitrile/malononitrile and 8-hydoxyquinoline is developed and presented in this paper. The cubic magnetic cobalt ferrite nano particles were synthesized by sol-gel citrate precursor method and characterized by FT-IR, XRD, sEM and TEM techniques and the structures of the synthesized pyranoquinoline derivatives were assigned by IR, MAss and 1sup>H NMR techniques. The reaction is carried out in a domestic microwave oven with a heat-resistant microwave safe glass container with a lid.

关键词： synthesis of 4H-Pyrano[3 2-h]quinoline Derivatives Microwave Irradiation Nano Cobalt Ferrite Catalyst