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Journal of Forensic science and Medicine 2024年第1期10卷 55-61页

作者： Mohan Kumar Pasupuleti Rasagna Chowdary G Gautami sPenmetsa vivek Bypalli ramesh s.v.konathala sruthima N.v.s.Gottumukkala Department of Periodontics and Implantology Vishnu Dental CollegeBhimavaramAndhra PradeshIndia2Vishnu Dental CollegeBhimavaramAndhra PradeshIndia

Aim:The aim of this study was to compare and investigate the tissue thickness at the maxillary and mandibular central incisors utilizing the probe visibility method and traditional way of measuring gingival thickness(GT)by endodontic ***:In 200 selected patients,the GT was measured at both the maxillary and mandibular anterior using an endodontic file after local infiltration at the mid-distance from the gingival margin to the mucogingival *** checkpoint of transition from thin to thick periodontal phenotype was determined by probe visibility method in the following age groups:Group A:21-30 years;Group B:31-40 years;Group C:41-50 years;and Group D:51-60 ***:GT varied from 0.3 to 1.9 *** translucency was observed up to the thickness of 0.7 *** 0.8 mm of GT,there was no probe ***:According to the present research,the gingiva appears transparent up to a thickness of around 0.7 *** checkpoint of transition between thin and thick periodontal phenotypes at both the maxillary and mandibular anterior was associated with a GT of 0.8 mm.

关键词： Gingiva periodontal phenotype probe visibility

Rational manipulation of electrolyte to induce homogeneous sEI on hard carbon anode for sodium-ion battery

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Journal of Energy Chemistry 2024年第7期94卷 414-429页

作者： Lu Liu Lingling Xiao Zhi sun shahid Bashir ramesh Kasi Yonghong Gu ramesh subramaniam Research Center for Clean Utilization Technology Phosphorous Resources Hubei Three Gorges PolytechnicYichang 443000HubeiChina Department of Physics Faculty of ScienceUniversiti MalayaKuala Lumpur 50603Malaysia UM Power Energy Dedicated Advanced Centre(UMPEDAC) Level 4Wisma R&DUniversiti MalayaKuala Lumpur 59990Malaysia Department of Chemistry Saveetha School of EngineeringInstitute of Medical and Technical ScienceSaveetha UniversityChennai 602105TamilnaduIndia

sodium-ion batteries (sIBs) have great potential to be the next major energy storage devices due to their obvious advantages and developing advanced electrodes and electrolytes is urgently necessary to promote its future ***,hard carbon as a state-of-the-art anode of sIBs still suffers from the low initial Coulomb efficiency and unsatisfactory rate capability,which could be improved by forming desirable solid electrolyte interphases (sEI) to some ***,the chemistry and morphology of these interfacial layers are fundamental parameters affecting the overall battery operation,and optimizing the electrolyte to dictate the quality of sEI on hard carbon is a key ***,this review summarizes the recent research on sEI design by electrolyte manipulation from solvents,salts,and *** also presents some potential mechanisms of sEI formation in various electrolyte ***,the current advanced characterization techniques for electrolyte and sEI structure analyses have been comprehensively ***,current challenges and future perspectives of sEI formation on hard carbon anode for sIBs are provided from the viewpoints of its compositions,evolution processes,structures,and characterization techniques,which will promote sEI efficient manipulation and improve the performance of hard carbon,and further contribute to the development of sIBs.

关键词： sEI Electrolyte optimization Hard carbon Electrochemical performance sodium-ion batteries

Microstructural characterization,tribological and corrosion behavior of AA7075-TiC composites

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China Foundry 2024年第4期21卷 334-342页

作者： surendarnath sundaramoorthy ramesh Gopalan Ramachandran Thulasiram Department of Mechanical Engineering DVR&Dr.HS MIC College of Technology(A)Vijayawada521180India Department of Metallurgical and Materials Engineering Rajiv Gandhi University of Knowledge TechnologiesRK ValleyKadapaIndia Department of Mechanical Engineering Jain UniversityBangaloreIndia

Aluminum alloys are the potential materials in the automobile and aerospace sectors due to their lower density,easy forming and excellent corrosion *** demand of high strength-to-weight ratio materials in structural applications needs the engineering industries to seek aluminum alloy with new versions of hard and brittle ceramic *** microstructure,hardness,wear and corrosion behaviors of AA7075 composites with 2.5wt.%and 5wt.%TiC particles were *** analysis is evident that the transformation of the strong dendritic morphology to non-dendritic morphology on the incorporation of TiC into ***,the precipitation of the second-phase compounds such as Al_(2)CuMg,Al_(2)Cu andFe-rich Al_6(Cu,Fe)/Al_(7)Cu_(2)Fe)is promoted by TiC particles at inter-and intra-dendritic ***,the hardness of composites is improved by grain boundary strengthening and particulate strengthening *** coefficient of friction and wear rate have an inverse relation with TiC *** base alloy without TiC shows adhesive-type wear-induced deformation due to the formation of an oxide film,while composite samples exhibit a mechanically mixed layer and abrasive-type wear *** samples shows a higher corrosion rate due to the presence of numerous precipitates which promote pitting corrosion.

关键词： AA7075 alloy TiC reinforcement composite microstructure wear corrosion tribological

Multi-scale habitat influences sprainting and group size of a freshwater-obligate smooth-coated otter(Lutrogale perspicillata) in Tungabhadra Otter Conservation Reserve, India

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Ecological Processes 2024年第1期13卷 159-175页

作者： Ankit Moun P.ramesh Kumar M.Malathi Priya T.ramesh Riddhika Kalle sálim Ali Centre for Ornithology and Natural History Deputy Conservator of Forests Bellary Territorial Forest Division Deputy Conservator of Forests Working Plan and Survey and Research WingBellary Territorial Forest Division Centre for Functional Biodiversity University of Kwa Zulu-Natal

Background The impact of changing land-use patterns and associated anthropogenic threats on scale-dependent habitat use of semi-aquatic mustelids in scent-marking and social behaviour can provide important insights into the habitat ecology of smooth-coated otters(Lutrogale perspicillata).Methods We sampled 180 stream segments(100–400 m) as spatial replicates of 60 1-km2 sites to record indirect evidence(i.e. spraints and mass latrine sites) and group sizes of smooth-coated otters along the Tungabhadra Otter Conservation Reserve(TOCR) during the dry season. To quantify habitat, we recorded stream characteristics, riparian vegetation, and anthropogenic disturbances at the local scale, and hydro-environmental characteristics and land uses at the landscape scale. Using Markovian-chain detection and occupancy models, we assessed the multi-scale habitat use of otters in their selection of suitable areas for scent-marking based on repeated presence-absence data on spraint/latrine locations along the TOCR. We further used linear regression techniques to explore relationships between the number of individuals in smooth-coated otter group and hydro-environmental characteristics, spraint/latrine encounter rate, anthropogenic pressure, land cover, topography, and *** At the local scale, the probability of spraint deposition and group size decreased with anthropogenic disturbance while the probability of spraint detections decreased with grass cover. At the landscape scale, the probability of otter site use for spraint deposition and group sizes increased in southeast flowing streams. spraint deposition increased with the proportion of sugarcane fields, whereas in contrast, group size decreased with proportion of sugarcane *** Our findings highlight the first empirical evidence on multi-scale habitat use of a southern Indian population of smooth-coated otters in an inland freshwater ecosystem surrounded by the scrub jungle–agriculture matrix. We sug

关键词： Presence-absence modelling Inland river Freshwater ecosystem semi-aquatic mammal smooth-coated otter

Foeniculum vulgare *** lipopolysaccharide-induced microglia activation and ameliorates neuroinflammation-mediated behavioral deficits in mice

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Asian Pacific Journal of Tropical Biomedicine 2024年第1期14卷 28-39页

作者： sushruta Koppula ramesh Alluri spandana Rajendra Kopalli College of Biomedical and Health sciences Konkuk UniversityChungju-SiChungcheongbuk Do27478Republic of Korea Cognitive science Research Initiative Lab Department of PharmacologyVishnu Institute of Pharmaceutical Education and ResearchNarsapurTelangana502313India Department of Bioscience and Biotechnology Sejong UniversityGwangjin-guSeoul 05006Republic of Korea

Objective:To investigate the effect of Foeniculum vulgare extract against lipopolysaccharide(LPs)-induced microglial activation in vitro as well as cognitive behavioral deficits in ***:LPs-activated Bv-2 cell viability was measured using MTT assay and reactive oxygen species(ROs)was studied using DCF-DA *** antioxidative enzymes and pro-inflammatory mediators were analyzed using respective ELIsA kits and Western *** in vivo testing,LPs(1 mg/kg,i.p.)was given daily for five days in male swiss albino mice to produce chronic *** and behavioral tests were performed using open-field,passive avoidance,and rotarod experiments in LPs-induced ***:Foeniculum vulgare extract(25,50 and 100μg/mL)significantly attenuated the LPs-activated increase in nitric oxide(NO),ROs,cyclooxygenase-2,inducible NO synthase,IL-6,and TNF-alpha(Pver,LPs-induced oxidative stress and reduced antioxidative enzyme levels were significantly improved by Foeniculum vulgare extract(Pso regulated the NF-κB/MAPK signaling in Bv-2 *** an in vivo study,Foeniculum vulgare extract(50,100,and 200 mg/kg)markedly mitigated the LPs-induced cognitive and locomotor impairments in *** fingerprinting analysis showed distinctive peaks with rutin,kaempferol-3-O-glucoside,and anethole as identifiable ***:Foeniculum vulgare extract can ameliorate LPs-stimulated neuroinflammatory responses in Bv-2 microglial cells and improve cognitive and locomotor performance in LPs-administered mice.

关键词： Foeniculum vulgare Microglia Lipopolysaccharide Antioxidant Neuroinflammation MAPK signaling Cognition

Disorders of potassium homeostasis after kidney transplantation

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World Journal of Transplantation 2024年第3期14卷 40-51页

作者： Abdelhamid Aboghanem G v ramesh Prasad school of Medicine University of TorontoToronto M5C 2T2OntarioCanada Kidney Transplant Program St.Michael's HospitalToronto M5C 2T2OntarioCanada

Disturbances of potassium balance are often encountered when managing kidney transplant recipients(KTR).Both hyperkalemia and hypokalemia may present either as medical emergencies or chronic outpatient *** the high incidence of hyperkalemia and its potential life-threatening implications,consensus on its management in KTR is *** in KTR is also well-described,although it is given less attention by clinicians compared to *** article discusses the etiology,pathophysiology and management of both types of potassium disorders in *** any emergent situation has been corrected,treatment approaches include correcting insulin deficiency if present,adjusting non-immunosuppressive and immunosuppressive medications,elimi-nating or supplementing potassium as needed,and dietary *** commonly of multifactorial etiology,ascertaining the specific cause in a particular patient will help guide successful *** KTR through regular laboratory testing is essential to detect serious disturbances in potassium balance since patients are often asymptomatic.

关键词： Balance Dialysis Hyperkalemia Hypokalemia Kidney Metabolism Potassium

Comparison of the Anatomy and Adaptability of Reconstructed Teeth with Natural Teeth:An Innovative Approach in Forensic Dentistry

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Journal of Forensic science and Medicine 2024年第1期10卷 47-54页

作者： supraja s P M Tejaswi Ravikanth Manyam Mohan Kumar Pasupuleti swetha P ramesh Kumar Budumuru Department of Oral and Maxillofacial Pathology Vishnu Dental CollegeBhimavaramAndhra PradeshIndia vishnu Dental College BhimavaramAndhra PradeshIndia Department of Periodontics and Implantology Vishnu Dental CollegeBhimavaramAndhra PradeshIndia Department of Oral Medicine and Radiology Vishnu Dental CollegeBhimavaramAndhra PradeshIndia

Background:Forensic tooth reconstruction is the technique of reconstructing the morphology of a missing tooth from the intra-alveolar morphology of dental sockets from skeletal *** and Objectives:The aim and objective of the study are to compare and investigate whether the anatomy and adaptability of reconstructed teeth simulate with the natural tooth and to investigate whether the dental materials have potential in reconstruction of *** and Methods:An in vitro experimental study was undertaken on a human *** to the Fédération Dentaire Internationale,charting will be done based on the number of teeth *** entire study will be conducted in three phases using dental *** 1 comprised preparation for negative replica,where an impression will be taken,Phase 2 comprised preparation of a positive replica or cast,and Phase 3 comprised tooth reconstruction using the flowable ***:The specimen tooth(which had been taken from its socket)and the newly constructed tooth were compared,and when the length of the newly constructed root was measured using digital vernier calipers,there was a disparity of 0.5-1 *** cone-beam computed tomography radiographs demonstrated the necessary ***:The present study demonstrated that dental information can be obtained even when teeth are absent postmortem by making an attempt to recreate the teeth using dental materials while documenting the intra-alveolar anatomy of the dental root socket.

关键词： Adaptability anatomy reconstruction teeth

Navigating the intersection of psychiatry and ophthalmology:A comprehensive review of depression and anxiety management in glaucoma patients

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World Journal of Psychiatry 2024年第3期14卷 362-369页

作者： Prasanna venkatesh ramesh Arvind Kumar Morya Ashik Azad Pavithra Pannerselvam Aji Kunnath Devadas sai Thaejesvi Gopalakrishnan shruthy vaishali ramesh Ajanya K Aradhya Department of Glaucoma and Research Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Optometry and visual science Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia Junior Resident Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia Department of Cataract and Refractive surgery Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia

Glaucoma,a prevalent and debilitating eye disease,has long been associated with vision impairment and ***,recent research has shed light on the often-underestimated psychological dimensions of this *** and depression,two pervasive psychiatric comorbidities,have been increasingly recognized among glaucoma *** comprehensive review aims to explore the intricate relationship between psychiatry and ophthalmology,in the context of managing depression and anxiety in glaucoma *** meticulously examining peer-reviewed literature,we synthesize current knowledge on the prevalence,risk factors,and underlying mechanisms of anxiety and depression in *** evidence reveals that glaucoma patients face an elevated risk of experiencing these mood *** such as progressive vision loss,complex medication regimens,and the fear of further visual deterioration contribute to their ***,we delve into the bidirectional relationship between glaucoma and mood disorders,shedding light on the complex interplay between ocular and emotional *** review investigates the implications of anxiety and depression on glaucoma management,including their potential impact on treatment adherence,disease progression,and overall quality of *** also explore the neurobiological pathways linking glaucoma and mood disorders,providing a foundation for future research and potential therapeutic *** conclusion,recognizing the psychological burden carried by glaucoma patients is essential for holistic and patient-centered *** review underscores the pressing need for integrated approaches that bring together ophthalmological and psychiatric expertise to optimize the well-being of individuals facing the challenges of *** addressing anxiety and depression in glaucoma care,healthcare providers can enhance the overall quality of life for these patients,ultimately leading to improved outcomes and a brighter

关键词： Glaucoma Psychiatry Depression Anxiety Risk factors Bidirectional relationship

Biological,pathological,and multifaceted therapeutic functions of exosomes to target cancer

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Oncology Research 2024年第1期32卷 73-94页

作者： vIGNEsH BALAJI E DIvYA ramesh MANIsHA CHUNGAN sHAJU AKsHARA KUMAR sAMYAK PANDEY RAKsHA NAYAK v.ALKA sRIsHTI MUNJAL AMIR sALIMI K.sREEDHARA RANGANATH PAI sHANKAR M.BAKKANNAvAR Department of Pharmacology Manipal College of Pharmaceutical SciencesManipal Academy of Higher EducationManipalKarnataka576104India Department of Forensic Medicine and Toxicology Kasturba Medical CollegeManipal Academy of Higher EducationManipalKarnataka576104India school of Health and Community services Durham CollegeOshawaOntarioL1G2G5Canada Department of Pharmaceutical Regulatory Affairs and Management Manipal College of Pharmaceutical SciencesManipal Academy of Higher EducationManipalKarnataka576104India Department of Clinical Psychology Manipal College of Health ProfessionsManipal Academy of Higher EducationManipalKarnataka576104India Department of speech and Hearing Manipal College of Health ProfessionsManipal Academy of Higher EducationManipalKarnataka576104India Department of Pharmacy Practice Manipal College of Pharmaceutical SciencesManipal Academy of Higher EducationManipalKarnataka576104India

Exosomes,small tiny vesicle contains a large number of intracellular particles that employ to cause various diseases and prevent several pathological events as well in the human *** is considered a“double-edged sword”,and depending on its biological source,the action of exosomes varies under physiological ***,the isolation and characterization of the exosomes should be performed accurately and the methodology also will vary depending on the exosome ***,the uptake of exosomes from the recipients’cells is a vital and initial step for all the physiological *** are different mechanisms present in the exosomes’cellular uptake to deliver their cargo to acceptor *** the exosomal uptake takes place,it releases the intracellular particles that leads to activate the physiological *** though exosomes have lavish functions,there are some challenges associated with every step of their preparation to bring potential therapeutic ***,overcoming the pitfalls would give a desired quantity of exosomes with high purity.

关键词： Exosomes Physiology Cancer Therapeutics Challenges

Unveiling the silent link:Normal-tension glaucoma's enigmatic bond with cardiac blood flow

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World Journal of Cardiology 2024年第1期16卷 10-15页

作者： Prasanna venkatesh ramesh Arvind Kumar Morya Ajanya K Aradhya Pavithra Pannerselvam sai Thaejesvi Gopalakrishnan shruthy vaishali ramesh Aji Kunnath Devadas Navaneeth Krishna Department of Glaucoma and Research Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia Department of Ophthalmology All India Institute of Medical SciencesHyderabad 508126TelanganaIndia Department of Optometry and visual science Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia Mahathma Eye Hospital Private Limited Trichy 620017Tamil NaduIndia Department of Cataract and Refractive surgery Mahathma Eye Hospital Private LimitedTrichy 620017Tamil NaduIndia

This comprehensive review embarks on a captivating journey into the complex relationship between cardiology and normal-tension glaucoma(NTG),a condition that continues to baffle clinicians and researchers ***,characterized by optic nerve damage and visual field loss despite normal intraocular pressure,has long puzzled *** emerging perspective suggests that alterations in ocular blood flow,particularly within the optic nerve head,may play a pivotal role in its *** NTG shares commonalities with its high-tension counterpart,its unique pathogenesis and potential ties to cardiovascular health make it a fascinating subject of *** navigates through the complex web of vascular dysregulation,blood pressure and perfusion pressure,neurovascular coupling,and oxidative stress,seeking to uncover the hidden threads that tie the heart and eyes together in *** review explores into the intricate mechanisms connecting cardiovascular factors to NTG,shedding light on how cardiac dynamics can influence ocular health,particularly in cases where intraocular pressure remains within the normal ***'s enigmatic nature,often characterized by seemingly contradictory risk factors and clinical profiles,underscores the need for a holistic approach to patient *** parallels to cardiac health,we examine into the shared vascular terrain connecting the heart and the *** factors,including systemic blood flow,endothelial dysfunction,and microcirculatory anomalies,may exert a profound influence on ocular perfusion,impacting the delicate balance within the optic nerve *** elucidating the subtle clues and potential associations between cardiology and NTG,this review invites clinicians to consider a broader perspective in their evaluation and management of this elusive *** the understanding of these connections evolves,so too may the prospects for early diagnosis and tailored interventions,ultimately enhancing the qual

关键词： Normal tension glaucoma vascular dysregulation Ocular blood flow Blood pressure Perfusion pressure Oxidative stress