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Efficacy of gabapentin for low back pain at a tertiary hospital: A prospective observational study

Journal of Acute Disease 2022年第3期11卷 101-106页

作者： Navaneetha Krishnan Subramanian VV.ramesh chandra Karthikeyan Elumalai Narahari N Palei Tiruveedi Kusuma Vadlamuri Venkata Prasad Yellanti Bala Venkata Bhargav Phani Mungara Yeshwanth Sai Pradeep Battula Anna Balaji Department of Pharmacology Dr.Kalam College of PharmacyPeriyanayagipuram 614623India Department of Neurosurgery Sri Venkateswara Institute of Medical SciencesTirupati 517102India Faculty of Pharmacy Bharath Institute of Higher Education and ResearchSelaiyur 600073India School of Pharmacy the Neotia UniversitySarisha 743368India Department of Pharmacy Practice Sree Vidyanikethan College of PharmacyTirupati 517102India Departments of Pharmacy Practice Santhiram College of PharmacyNandyal 518501India Departments of Pharmaceutics Sree Vidyanikethan College of PharmacyTirupati 517102India

Objective:To assess the efficacy of gabapentin in the treatment of low back pain ***:This prospective observational study was conducted over 6 months to assess the efficacy of gabapentin in patients suffering from low back *** medical history,pain severity by Visual Analogue scale(VAS)and sleep quality by Pittsburgh Sleep Quality Index(PQSI)were *** scores and PQSI scores before and after gabapentin treatment were compared,and gabapentin satisfaction post treatment were ***:This study included 100 low back pain patients with 65 males and 35 females,and the mean age was(39.0±10.5)*** commonest presentation was non-radiating low back pain(40%).The mean VAS score and the mean PQSI score in the study before treatment were 7.70±1.91 and 10.95±5.02,*** treatment with gabapentin,the mean VAS score and the mean PQSI score decreased to 2.75±1.79 and 4.90±2.20,respectively,and the differences before and after the treatment were significantly different(both P=0.001).Overall,62%of the patients were extremely satisfied with gabapentin because they reported no adverse drug ***,31%of the patients were satisfied and 7%were strongly dissatisfied with the ***:Gabapentin can improve sleep quality and reduce lower back pain as measured by the VAS and *** efficacy of this drug is relatively good,but further improvement is required.

关键词： Gabapentin Low back pain Sleep Pittsburgh Sleep Quality Index Visual Analogue Scale

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Perioperative mortality and morbidity of hip fractures among COVID-19 infected and non-infected patients: A systematic review and meta-analysis

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Chinese Journal of Traumatology 2023年第3期26卷 162-173页

作者： Sujit Kumar Tripathy Paulson Varghese Sibasish Panigrahi Bijnya Birajita Panda Anand Srinivasan ramesh Kumar Sen Department of Orthopedics All India Institute of Medical SciencesBhubaneswar751019India Department of Ophthalmology Srirama Chandra Bhanja Medical College and HospitalCuttack753007India Department of Pharmacology All India Institute of Medical SciencesBhubaneswar751019India Department of Orthopaedics Max HospitalMohali160055India

Purpose:Hip fractures among elderly patients are surgical *** COVID-19 pandemic time,many such patients could not be operated at early time because of the limitation of the medical resources,the risk of infection and redirection of medical attention to a severe infective health ***:A search of electronic databases(PubMed,Medline,CINAHL,EMBASE and the Cochrane Central Register of Controlled Trials)with the keywords"COVID","COVID-19","SARS-COV-2","Corona","pandemic","hip fracture","trochanteric fracture"and"neck femur fracture"revealed 64 studies evaluating treatment of hip fracture in elderly patients during COVID-19 pandemic *** 30-day mortality rate,inpatient mortality rate,critical care/special care need,readmission rate and complications rate in both groups were *** were analyzed using Review Manager(RevMan)***:After screening,7 studies were identified that described the mortality and morbidity in hip fractures in both COVID-19 infected(COVID-19+)and non-infected(COVID-19-)*** were significantly increased risks of 30-day mortality(32.23%COVID-19+deathvs.8.85%COVID-19-death)and inpatient mortality(29.33%vs.2.62%)among COVID-19+patients with odds ratio(OR)of 4.84(95%CI:3.13-7.47,p<0.001)and 15.12(95%CI:6.12-37.37,p<0.001),*** COVID-19+patients needed more critical care admission(OR=5.08,95%CI:1.49-17.30,p<0.009)and they remain admitted for a longer time in hospital(mean difference=3.6,95% CI:1.74-5.45,p<0.001);but there was no difference in readmission rate between these 2 *** risks of overall complications(OR=17.22),development of pneumonia(OR=22.25),and acute respiratory distress syndrome/acute respiratory failure(OR=32.96)were significantly high among COVID-19+patients compared to ***:There are increased risks of the 30-day mortality,inpatient mortality and critical care admission among hip fracture patients who are COVID-19+.The chances of developing pn

关键词： Hip fracture Femur neck fracture Mortality COVID-19 Pandemic

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铁-铬结合鞣法生产软革

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北京皮革（中外皮革信息版）（中） 2009年第2期 94-101页

作者： R Karth I keyan. R. ramesh. R. Usha. B. Ramana I ah. N. K. chandra Babu 郝霞（译）印度中央皮革研究所制革厂分部 Adyar Chenna I 600020 不详

寻找更加安全的鞣制方法一直是制革行业的研究方向。由于在水溶液中与Cr（Ⅲ）具有相似的化学性质，Fe（Ⅲ）盐常常被认为是一种可能取代铬盐的鞣剂。但是，在制革工业中使用Fe（Ⅲ）鞣法，仍然存在一些局限性。其中一个主要问题就是铁... 详细信息

寻找更加安全的鞣制方法一直是制革行业的研究方向。由于在水溶液中与Cr（Ⅲ）具有相似的化学性质，Fe（Ⅲ）盐常常被认为是一种可能取代铬盐的鞣剂。但是，在制革工业中使用Fe（Ⅲ）鞣法，仍然存在一些局限性。其中一个主要问题就是铁鞣法不能用来生产软革，例如服装革、手套革。为了克服该问题，本文尝试用铁鞣法来生产山羊绒而和绵羊纳帕服装革。试验优化了铁-铬结合鞣法，同时将鞣制废液中铬和铁的含量部降低到了100mg／L以下。为了研究铁-铬结合鞣法对皮革结构的影响，本文采用了扫描电子显微镜对鞣革进行分析。另外，对鞣革的强度和颜色特征也进行了表征和分析。

关键词：结合鞣法铬盐生产软革扫描电子显微镜铁 Fe(Ⅲ) 鞣制方法

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