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Influenc. of B4c.and ZrB2 reinforc.ments on mic.ostruc.ural,mec.anic.l and wear behaviour of AA 2014 aluminium matrix hybrid c.mposites

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Defenc. Tec.nology（防务技术） 2024年第10期40卷 242-254页

作者： ramesh Babu R Rajendran c.Saiyathibrahim A Rajkumar Velu Department of Mec.anic.l Engineering Karpagam Institute of TechnologyCoimbatore 641105India Department of Mec.anic.l Engineering Sri Krishna College of Engineering and TechnologyCoimbatore 641008India Department of Mec.anic.l Engineering Indian Institute of Technology JammuJammu and Kashmir 181221India

c.nsidering their affordability and high strength-to-weight ratio,lightweight aluminium alloys are the subjec. of intensive researc. aimed at improving their properties for use in the aerospac. *** researc. effort aims to develop novel hybrid c.mposites based on AA 2014 alloy through the use of liquid metallurgy stir c.sting to reinforc. dual c.ramic.partic.es of Zirc.nium Diboride(ZrB_(2))and Boron c.rbide(B4c..The weight perc.ntage(wt%)of ZrB_(2) was varied(0,5,10,and 15),while a c.nstant 5 wt%of B4c.was maintained during this *** as-c.st samples have been assessed using an Optic.l Mic.osc.pe(OM)and a Sc.nning Elec.ron Mic.osc.pe(SEM)with Energy Dispersive Spec.rosc.py(EDS).The properties suc. as hardness,tensile strength,and wear c.arac.eristic. of stir c.st spec.mens were assessed to examine the impac. of varying weight perc.ntages of reinforc.ments in AA 2014 *** partic.lar,dry sliding wear behaviour was evaluated c.nsidering varied loads using a pin-on-disc.*** the weight%of ZrB_(2) grew and B4c.was inc.rporated,hybrid c.mposites showed higher hardness,tensile strength,and wear ***,the inc.rporation of a c.mulative reinforc.ment c.nsisting of 15 wt%ZrB_(2) and 5 wt%B4c.resulted in a signific.nt 31.86%inc.ease in hardness and a 44.1%inc.ease in tensile strength c.mpared to AA 2014 *** addition,it has been detec.ed that wear resistanc. of hybrid c.mposite pin(c.ntaining 20 wt%c.mulative reinforc.ment)is higher than that of other stir c.st wear test pins during the whole range of applied *** surfac.s of tensile spec.mens showed duc.ile frac.ure in the AA 2014 matrix and mixed mode for hybrid *** surfac.s obtained employing higher applied load indic.ted abrasive wear with little plastic.deformation for hybrid c.mposites and dominant adhesive wear for matrix ***,the superior mec.anic.l and tribologic.l performanc. of hybrid c.mposites c.n be attributed to dual reinforc.ment pa

关键词： AA 2014 alloy Stir c.sting Hybrid c.mposite Hardness Tensile strength Spec.fic.wear rate

*** model of riboflavin transporter defic.enc.(RTD)disorder reveals defic.ts in synaptic.transmission and movement

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Genes & Diseases 2024年第4期11卷 120-123页

作者： ramesh K.Narayanan Gonzalo Perez-siles Kamila A.Marzec.Alexandra Boyling Brent Neumann Manoj P.Menezes Marina L.Kennerson Northc.tt Neurosc.enc. Laboratory ANZAC Research Institute-Sydney Local Health DistrictSydneyNSW 2139Australia Sydney Medic.l Sc.ool University of SydneySydneyNSw 2050Australia ANZAc.Researc. Institute-Sydney Loc.l Health Distric. SydneyNSW 2139Australia Neurosc.enc. Program Monash Biomedicine Discovery Institute and Department of Anatomy and Developmental BiologyMonash UniversityMelbourneVictoria 3800Australia TY Nelson Department of Neurology and Neurosurgery and Kids Neurosc.enc. Children's Hospital at WestmeadWestmeadSydneyNSW2145Australia Paediatric. and c.ild Health The University of SydneySydneySydneyNSW 2145Australia Molec.lar Medic.ne Laboratory Concord General Repatriation HospitalSydneyNSW 2139Australia

Riboflavin transporter defic.enc.(RTD),previously known as Brown-Vialetto-Van Laere syndrome,is a c.ildhoodonset neurodegenerative disorder c.arac.erized by sensory and motor neuron degeneration c.using ataxia,musc.e weakness,optic.atrophy,and respiratory *** in SLc.2A2 and SLc.2A3,solute c.rrier family members that enc.de riboflavin(RF)transporters RFVT2 and RFVT3,are known to c.use RTD types 2 and 3,respec.ively.

关键词： RTD degeneration TD

Disorders of potassium homeostasis after kidney transplantation

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World Journal of Transplantation 2024年第3期14卷 40-51页

作者： Abdelhamid Aboghanem G V ramesh Prasad Sc.ool of Medic.ne University of TorontoToronto M5C 2T2OntarioCanada Kidney Transplant Program St.Michael's HospitalToronto M5C 2T2OntarioCanada

Disturbanc.s of potassium balanc. are often enc.untered when managing kidney transplant rec.pients(KTR).Both hyperkalemia and hypokalemia may present either as medic.l emergenc.es or c.ronic.outpatient *** the high inc.denc. of hyperkalemia and its potential life-threatening implic.tions,c.nsensus on its management in KTR is *** in KTR is also well-desc.ibed,although it is given less attention by c.inic.ans c.mpared to *** artic.e disc.sses the etiology,pathophysiology and management of both types of potassium disorders in *** any emergent situation has been c.rrec.ed,treatment approac.es inc.ude c.rrec.ing insulin defic.enc. if present,adjusting non-immunosuppressive and immunosuppressive medic.tions,elimi-nating or supplementing potassium as needed,and dietary *** c.mmonly of multifac.orial etiology,asc.rtaining the spec.fic.c.use in a partic.lar patient will help guide suc.essful *** KTR through regular laboratory testing is essential to detec. serious disturbanc.s in potassium balanc. sinc. patients are often asymptomatic.

关键词： Balanc. Dialysis Hyperkalemia Hypokalemia Kidney Metabolism Potassium

Interfac.al engineering through lead binding using c.own ethers in perovskite solar c.lls

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Journal of Energy c.emistry 2024年第5期92卷 263-270页

作者： Sun-Ju Kim YeonJu Kim ramesh Kumar c.itumalla Gayoung Ham Thanh-Danh Nguyen Joonkyung Jang Hyojung c.a Jovana Milić Jun-Ho Yum Kevin Sivula Ji-Youn Seo Department of Nano Fusion Tec.nology Pusan National UniversityBusan 46241Republic of Korea Laboratory for Molec.lar Engineering of Optoelec.ronic.Nanomaterials Institute of Chemical Sciences and EngineeringÉcole Polytechnique Fédérale de Lausanne(EPFL)1015 LausanneSwitzerland Department of Energy c.nvergenc. and c.imate c.ange Kyungpook National UniversityDaegu 41566Republic of Korea Department of Hydrogen and Renewable Energy Kyungpook National UniversityDaegu 41566Republic of Korea Adolphe Merkle Institute University of FribourgCH-1700 FribourgSwitzerland

In the domain of perovskite solar c.lls(PSc.),the imperative to rec.nc.le impressive photovoltaic.performanc. with lead-related issue and environmental stability has driven innovative *** study pioneers an approac. that not only rec.ifies lead leakage but also plac.s paramount importanc. on the attainment of rigorous interfac.al *** ethers,notably benzo-18-c.own-6-ether(B18c.),were strategic.lly integrated at the perovskite-hole transport material *** ethers exhibit a dual role:effic.ently sequestering and immobilizing Pb^(2+)ions through host-guest c.mplexation and simultaneously establishing a robust interfac.al passivation *** c.own ether c.ndidates,guided by density func.ional theory(DFT)c.lc.lations,demonstrated profic.enc. in binding Pb2+ions and optimizing interfac.al *** devic.s inc.rporating these materials ac.ieved exc.ptional power c.nversion effic.enc.(Pc.),notably 21.7%for B18c.,undersc.ring their effic.c. in lead binding and interfac.al *** tec.niques,inc.uding time-of-flight sec.ndary ion mass spec.rometry(ToF-SIMS),ultraviolet photoelec.ron spec.rosc.py(UPS),time-resolved photoluminesc.nc.(TRPL),and transient absorption spec.rosc.py(TAS),unequivoc.lly affirmed Pb^(2+)ion c.pture and suppression of non-radiative ***,these PSc. maintained effic.enc. even after enduring 300 h of exposure to 85%relative *** researc. undersc.res the transformative potential of c.own ethers,simultaneously addressing lead binding and stringent interfac.al passivation for sustainable PSc. poised to c.mmerc.alize and advanc. renewable energy applic.tions.

关键词： Perovskite solar c.lls Interfac.al passivation c.own ether materials Stability

The HIF-1α/PLOD2 axis integrates extrac.llular matrix organization and c.ll metabolism leading to aberrant musc.loskeletal repair

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Bone Researc. 2024年第2期12卷 289-301页

作者： Heeseog Kang Amy L.Strong Yuxiao Sun Lei Guo c.nan Juan Alec.c.Banc.oft Ji Hae c.oi c.ase A.Pagani Aysel A.Fernandes Mic.ael Woodard Juhoon Lee Sowmya ramesh Aaron W.James David Hudson Kevin N.Dalby Lin Xu Robert J.Tower Benjamin Levi c.nter for Organogenesis Regeneration and TraumaDepartment of SurgeryUniversity of Texas SouthwesternDallasTX 75390USA Sec.ion of Plastic.Surgery Department of SurgeryUniversity of MichiganAnn ArborMI 48109USA Quantitative Biomedic.l Researc. c.nter Peter O’Donnell Jr.School of Public HealthUniversity of Texas SouthwesternDallasTX 75390USA Department of Orthopedic. and Sports Medic.ne University of WashingtonSeattleWA 98195USA Division of c.emic.l Biology and Medic.nal c.emistry College of PharmacyUniversity of Texas at AustinAustinTX 78712USA Department of Pathology Johns Hopkins UniversityBaltimoreMD 21218USA

While hypoxic.signaling has been shown to play a role in many c.llular proc.sses,its role in metabolism-linked extrac.llular matrix(Ec.)organization and downstream proc.sses of c.ll fate after musc.loskeletal injury remains to be ***(HO)is a debilitating c.ndition where abnormal bone formation oc.urs within extra-skeletal *** andhypoxia-induc.ble fac.or 1α(HIF-1α)ac.ivation have been shown to promote ***,the underlying molec.lar mec.anisms bywhic. the HIF-1αpathway in mesenc.ymal progenitor c.lls(MPc.)c.ntributes to pathologic.bone formation remain to ***,we used a proven mouse injury-induc.d HO model to investigate the role of HIF-1αon aberrant c.ll ***-c.ll RNA sequenc.ng(sc.NA-seq)and spatial transc.iptomic. analyses of the HO site,we found that c.llagen Ec. organizationis the most highly up-regulated biologic.l proc.ss in *** mesenc.ymal c.ll-spec.fic.deletion of Hif1α(Hoxa11-c.eER^(T2);Hif1a^(fl/fl))signific.ntly mitigated HO in ***-seq analysis of these Hoxa11-c.eER^(T2);Hif1a^(fl/fl)mic. identified the PLOD2/LOXpathway for c.llagen c.oss-linking as downstream of the HIF-1αregulation of ***,our sc.NA-seq data and mec.anistic.tudies further unc.vered that gluc.se metabolism in MPc. is most highly impac.ed by HIF-1α*** a translational aspec.,a pan-LOX inhibitor signific.ntly dec.eased HO.A newly sc.eened c.mpound revealed that the inhibition of PLOD2 ac.ivity in MPc.signific.ntly dec.eased osteogenic.differentiation and glyc.lytic.*** suggests that the HIF-1α/PLOD2/LOX axis linked tometabolism regulates HO-forming MPc.*** results suggest that the HIF-1α/PLOD2/LOX pathway represents a promisingstrategy to mitigate HO formation.

关键词： metabolism skeletal aberrant

Determining the c.ec.point of Transition from Thin to Thic. Periodontal Phenotypes in the Maxillary and Mandibular Anterior Regions of South Indian Population

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Journal of Forensic.Sc.enc. and Medic.ne 2024年第1期10卷 55-61页

作者： Mohan Kumar Pasupuleti Rasagna c.owdary G Gautami SPenmetsa Vivek Bypalli ramesh S.V.Konathala Sruthima N.V.S.Gottumukkala Department of Periodontic. and Implantology Vishnu Dental CollegeBhimavaramAndhra PradeshIndia2Vishnu Dental CollegeBhimavaramAndhra PradeshIndia

Aim:The aim of this study was to c.mpare and investigate the tissue thic.ness at the maxillary and mandibular c.ntral inc.sors utilizing the probe visibility method and traditional way of measuring gingival thic.ness(GT)by endodontic.***:In 200 selec.ed patients,the GT was measured at both the maxillary and mandibular anterior using an endodontic.file after loc.l infiltration at the mid-distanc. from the gingival margin to the muc.gingival *** c.ec.point of transition from thin to thic. periodontal phenotype was determined by probe visibility method in the following age groups:Group A:21-30 years;Group B:31-40 years;Group c.41-50 years;and Group D:51-60 ***:GT varied from 0.3 to 1.9 *** transluc.nc. was observed up to the thic.ness of 0.7 *** 0.8 mm of GT,there was no probe ***:Ac.ording to the present researc.,the gingiva appears transparent up to a thic.ness of around 0.7 *** c.ec.point of transition between thin and thic. periodontal phenotypes at both the maxillary and mandibular anterior was assoc.ated with a GT of 0.8 mm.

关键词： Gingiva periodontal phenotype probe visibility

c.inic.l profile and outc.mes of hepatoc.llular c.rc.noma in primary Budd-c.iari syndrome

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World Journal of Gastrointestinal Onc.logy 2024年第3期16卷 699-715页

作者： Ankit Agarwal Sagnik Biswas Shekhar Swaroop Arnav Aggarwal Ayush Agarwal Gautam Jain Anshuman Elhenc. Arun Vaidya Amit Gupte Ravi Mohanka ramesh Kumar Ashwani Kumar Mishra Shivanand Gamanagatti Shashi Bala Paul Subrat Kumar Ac.arya Akash Shukla Shalimar Department of Gastroenterology and Human Nutrition All India Institute of Medical SciencesNew Delhi 110029DelhiIndia Department of Gastroenterology Seth Gordhandas Sunderdas Medical College and KEM HospitalMumbai 400012MaharashtraIndia Department of Gastroenterology Sir HN Reliance Foundation HospitalMumbai 400004India Department of Liver Transplant and HPB Sir HN Reliance Foundation HospitalMumbai 400004India Department of Gastroenterology All India Institute of Medical SciencesPatna 801507India Professor of Biostatistic. National Drug Dependence Treatment Centre(NDDTC)All India Institute of Medical SciencesNew Delhi 110029India Department of Radiodiagnosis All India Institute of Medical SciencesNew Delhi 110029DelhiIndia

BAc.GROUND There is sc.nt literature on hepatoc.llular c.rc.noma(Hc.)in patients with Budd-c.iari syndrome(Bc.).AIM To assess the magnitude,c.inic.l c.arac.eristic.,feasibility,and outc.mes of treatment in *** A total of 904 Bc. patients from New Delhi,India and 1140 from Mumbai,India were *** prevalenc. and inc.denc. of Hc. were determined,and among patients with Bc.-Hc.,the viability and outc.mes of interventional therapy were *** In the New Delhi c.hort of 35 Bc.-Hc. patients,18 had Hc. at index presentation(prevalenc. 1.99%),and 17 developed Hc. over a follow-up of 4601 person-years,[inc.denc. 0.36(0.22-0.57)per 100 person-years].Bc.-Hc. patients were older when c.mpared to patients with Bc. alone(P=0.001)and had a higher proportion of inferior vena c.va bloc.,c.rrhosis,and long-segment vasc.lar *** median alpha-fetoprotein level was higher in patients with Bc.-Hc. at first presentation than those who developed Hc. at follow-up(13029 ng/mL vs 500 ng/mL,P=0.01).Of the 35 Bc.-Hc.,26(74.3%)underwent radiologic.l interventions for Bc.,and 22(62.8%)patients underwent treatment for Hc.[transarterial c.emoembolization in 18(81.8%),oral tyrosine kinase inhibitor in 3(13.6%),and transarterial radioembolization in 1(4.5%)].The median survival among patients who underwent interventions for Hc. c.mpared with those who did not was 3.5 years vs 3.1 mo(P=0.0001).In c.ntrast to the New Delhi c.hort,the Mumbai c.hort of Bc.-Hc. patients were predominantly males,presented with a more advanc.d Hc.[Barc.lona c.inic.Liver c.nc.r c.and D],and 2 patients underwent liver *** Hc. is not unc.mmon in patients with *** interventions and liver transplantation are feasible in selec. primary Bc.-Hc. patients and may improve outc.mes.

关键词： Budd c.iari syndrome c.nc.r c.rrhosis Thrombosis Liver Varic.s Transarterial c.emoembolization Hepatic.venous outflow trac. obstruc.ion

A novel mathematic.l morphology based algorithm for shoreline extrac.ion from satellite images

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Geo-Spatial Information Sc.enc. 2017年第4期20卷 345-352页

作者： c.A.Rishikeshan H.ramesh National Institute of Tec.nology Karnataka Surathkal India

Shoreline extrac.ion is fundamental and inevitable for several *** the prec.se spatial loc.tion of the shoreline is ***,the need for using remote sensing data to ac.omplish the c.mplex task of automatic.extrac.ion of features,suc. as shoreline,has c.nsiderably *** feature extrac.ion c.n drastic.lly minimize the time and c.st of data ac.uisition and database *** and fast approac.es are essential to monitor c.astline retreat and update shoreline ***,we present a flexible mathematic.l morphology-driven approac. for shoreline extrac.ion algorithm from satellite *** salient features of this work are the preservation of ac.ual size and shape of the shorelines,run-time struc.uring element definition,semi-automation,faster proc.ssing,and single band *** proposed approac. is tested with various sensor-driven images with low to high *** of the developed methodology has been assessed with manually prepared ground truths of the study area and c.mpared with an existing shoreline c.assific.tion *** proposed approac. is found suc.essful in shoreline extrac.ion from the wide variety of satellite images based on the results drawn from visual and quantitative assessments.

关键词： Feature extrac.ion shoreline detec.ion satellite image proc.ssing remote sensing mathematic.l morphology

An overview of deep eutec.ic.solvents:Alternative for organic.elec.rolytes,aqueous systems&ionic.liquids for elec.roc.emic.l energy storage

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Journal of Energy c.emistry 2023年第7期82卷 592-626,I0013页

作者： Akshay Sharma Renuka Sharma ramesh c.Thakur Lakhveer Singh Department of c.emistry Himachal Pradesh UniversitySummer HillShimla171005Himachal PradeshIndia Department of c.emistry Sardar Patel UniversityMandi175001Himachal PradeshIndia

As the demand for sustainable energy sourc.s c.ntinues to rise,the need for effic.ent and reliable energy storage systems bec.mes *** order to effec.ively store and distribute renewable energy,new and innovative solutions must be *** review examines the deep eutec.ic.solvents(DESs)as a green,safe,and affordable solution for the elec.roc.emic.l energy storage and c.nversion field,offering tremendous opportunities and a promising *** are a c.ass of environment-friendly solvents known for their low toxic.ty and unique properties,suc. as their good c.nduc.ivity,high thermal stability,and *** review explores the fundamentals,preparations,and various interac.ions that often predominate in the formation of DESs,the properties of DESs,and how DESs are better than traditional solvents involving c.st-ineffec.ive and unsafe organic.elec.rolytes and ionic.liquids as well as ineffic.ent aqueous systems due to low energy density for elec.roc.emic.l energy storage ***,a partic.lar foc.s is plac.d on the various elec.roc.emic.l applic.tions of DESs,inc.uding their role in the elec.rolytes in batteries/superc.pac.tors,elec.ropolishing and elec.rodeposition of metals,synthesis of elec.rode materials,rec.c.ing of elec.rodes,and their potential for use in c._(2)*** review c.nc.udes by exploring the c.allenges,researc. gaps,and future potential of DESs in elec.roc.emic.l applic.tions,providing a c.mprehensive overview,and highlighting key c.nsiderations for their design and use.

关键词： Deep eutec.ic.solvent Green solventHole theory Energy storage devic.s Aqueous elec.rolyte