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Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients:A systematic review and meta-analysis of randomized controlled trials

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Journal of Sport and Health Science 2023年第2期12卷 147-157页

作者： Antonio García-Hermoso Robinson ramírez-Vélez Javier Díez Arantxa González Mikel Izquierdo Navarrabiomed Public University of Navarra(UPNA)Health Research Institute of Navarra(IdiSNA)University Hospital of NavarraPamplona 310008Spain CIBER of Frailty and Healthy Aging(CIBERFES) Carlos Ⅲ Institute of HealthMadrid 28029Spain Institute for Health Research of Navarra(IDISNA) Pamplona 31008Spain Program of Cardiovascular Diseases Center for Applied Medical ResearchUniversity of NavarraPamplona 31008Spain Centre for Biomedical Research in Cardiovascular Disease Network Carlos Ⅲ Institute of HealthMadrid 28029Spain Departments of Nephrology and Cardiology University of Navarra ClinicPamplona 31008Spain

Background:This study investigates the effects of exercise training on exerkines in patients with type 2 diabetes mellitus to determine the optimal exercise ***:A systematic search for relevant studies was performed in 3 *** controlled trials investigating the effects of exercise training on at least one of the following exerkines were included:adiponectin,apelin,brain-derived neurotrophic factor,fetuin-A,fibroblast growth factor-21,follistatin,ghrelin,interleukin(IL)-6,IL-8,IL-10,IL-15,IL-18,leptin,myostatin,omentin,resistin,retinol-binding protein 4,tumor necrosis factor-α,and ***:Forty randomized controlled trials were selected for data extraction(n=2160).Exercise training induces changes in adiponectin,fetuin-A,fibroblast growth factor-21,IL-6,IL-10,leptin,resistin,and tumor necrosis factor-a levels but has no significant effects on apelin,IL-18,and ghrelin compared to *** exercise training favored large and positive changes in pooled exerkines(i.e.,an overall effect size calculated from several exerkine s)(Hedge’s g=1.02,95%confidence interval(95%CI):0.76-1.28),which in turn were related to changes in glycated hemoglobin(mean difference(MD)=-0.81%,95%CI:-0.95%to-0.67%),fasting glucose(MD=-23.43 mg/dL,95%CI:-30.07 mg/dL to-16.80 mg/dL),waist circumference(MD=-3.04 cm,95%CI:-4.02 cm to-2.07 cm),and body mass(MD=-1.93 kg,95%CI:-2.00 kg to-1.86 kg).Slightly stronger effects were observed with aerobic,resistance,or high-intensity interval protocols at moderate-to vigorous-intensity and with programs longer than 24 weeks that comprise at least 3 sessions per week and more than 60 min per ***:Exercise training represents an anti-inflammatory therapy and metabolism-improving strategy with minimal side effects for patients with type 2 diabetes mellitus.

关键词： Adipokines Exercise training Hepatokines Myokines

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Phytogenic Synthesis of Metal/Metal Oxide Nanoparticles for Degradation of Dyes

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Journal of Renewable Materials 2022年第7期10卷 1911-1930页

作者： Arpita Roy H.CAnanda Murthy Hiwa M.Ahmed Mohammad Nazmul Islam ram Prasad Department of Biotechnology School of Engineering&TechnologySharda UniversityGreater Noida201310India Department of Applied Chemistry School of Applied Natural ScienceAdama Science and Technology UniversityAdama1888Ethiopia Sulaimani Polytechnic University Slemani46001Iraq Department of Horticulture University of RaparinRanya46012Iraq Department of Pharmacy International Islamic University ChittagongChittagong4318Bangladesh Department of Botany Mahatma Gandhi Central UniversityMotihari845401India

Now-a-days nanotechnology is one of the booming fields for the *** the increase in industrialization mainly textile,paper,medicine,plastic industry,there is an increase in concentration of organic dyes as *** of harmful dyes in water bodies has become a serious issue,as most of the dyes are carcinogenic and mutagenic in nature and causes various ***,there is a requirement to find out new approaches for efficient treatment of effluent containing *** are one of the potential solutions to this *** can be synthesized from different methods,however synthesis of nanoparticles from different plant parts(leaf,root or stem extract)is economical as well as *** nanoparticles have various environmental applications and one of them is remediation of *** aim of this review is to provide an overview of last five years studies about catalytic and photocatalytic degradation of various harmful dyes by plant synthesized nanoparticles,mechanism of degradation and advantages and disadvantages of phytogenic synthesis.

关键词： Nanoparticles green synthesis plants dyes remediation,metal oxide

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Effect of temperature on carrier transport and photoconductivity of Mn-doped FeS2 thin films

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Progress in Natural Science:Materials International 2022年第1期32卷 135-142页

作者： Jugraj Singh Kulwinder Singh Manjot Kaur Anup Thakur ram K.sharma Ankush Vij Akshay Kumar Department of Nanotechnology Sri Guru Granth Sahib World University Department of Basic and Applied Sciences Punjabi University Centre for Interdisciplinary Research University of Petroleum and Energy Studies (UPES) Department of Physics University of Petroleum and Energy Studies (UPES)

Thin-film of Mn-doped iron disulfide(FeS2) has been prepared using the thermal evaporation method. This work reports the Hall measurements, temperature and light intensity-dependent photoconductivity, electrical transport mechanism, and photodetection properties of Mn-doped FeS2thin film. The transient photoconductivity measurements of p-type Mn-doped FeS2thin film show a consistent dependence upon temperature and light *** transport mechanism was illustrated using different models. In region-Ⅰ(303–393 K) deposited film followed the thermally activated transport mechanism. Nearest neighbour hopping(NNH) transport mechanism was followed by region-Ⅱ(274–293 K), and Mott’s variable range hopping(VRH) mechanism was dominant in region Ⅲ(108–273 K). The fabricated device resulted in higher photoconductivity due to collecting charge carriers through electrodes under light illumination. The results also revealed that Mn-doped thin film possessed good photoresponsivity(～19 m A/W) as well as photo-detectivity(～3.4 × 1012Jones) due to the occupation of localized states formed by Mn-doping. Light intensity-dependent photodetection properties suggested the potential for real-time photodetection applications.

关键词： Mn-doped FeS 2 Charge transport Hopping mechanism Photodetection Responsivity

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Effect of the addition of different sodium alginates on viscoelastic,structural features and hydrolysis kinetics of corn starch gels

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Food Bioscience 2022年第3期47卷 271-278页

作者： Leticia Montes Maria Santamaria Raquel Garzon Cristina M.Rosell ramón Moreira Department of Chemical Engineering Universidade de Santiago de Compostelarúa Lope Gómez de Marzoas/n15782Santiago de CompostelaSpain Institute of Agrochemistry and Food Technology (IATA-CSIC).C/Agustin Escardino 746980PaternaSpain

Corn starch gels(1:4 w:w)were made with the addition(up to 2%w/w starch basis)of sodium alginates of different average molecular sizes and *** of the starchy gels were characterized to evaluate their *** were subjected to in vitro digestion to estimate the effect of alginates addition on glycemic *** alginates significantly decreased the value of the elastic modulus of *** coordination number obtained from complex modulus indicated that in general,less compact structures were obtained in the presence of *** results were confirmed by scanning electron micrographs,where significant differences in the structure of alginate-corn starch gels were observed,but molecular size of alginates was not *** rate decreased with the presence of alginates in corn starch gels by interactions of alginates with leached *** high alginate content,slower hydrolysis rates were determined when the most hygroscopic alginates were added.

关键词： Biopolymers In vitro digestion Average molecular weight Rheology Scanning electron microscopy(SEM)

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Hemodynamic instability following intravenous dexmedetomidine infusion for sedation under brachial plexus block: Two case reports

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World Journal of Clinical Cases 2023年第30期11卷 7469-7474页

作者： Ye Sull Kim Chanhong Lee Jeongmin Oh Seonhwa Nam A ram Doo Department of Anesthesiology and Pain Medicine Jeonbuk National University HospitalJeonju 54907South Korea Department of Anesthesiology and Pain Medicine Jeonbuk National University Medical School and HospitalJeonju 54907South Korea Department of Anesthesiology and Pain Medicine Research Institute of Clinical Medicine-Biomedical Research Institute of Jeonbuk National University HospitalJeonju 54907South Korea

BACKGROUND Dexmedetomidine(DMED)is frequently used as a sedative in several medical *** benefits of DMED include enhanced quality of regional anesthesia,prolonged analgesia,and postoperative opioid-sparing when administered intravenously or perineurally in combination with regional *** hemodynamic complications,such as profound bradycardia and hypotension,can occur after DMED administration in critically ill patients or overdosage;however,there are few reports of complications with DMED administration following brachial plexus block(BPB).CASE SUMMARY We present two cases of hemodynamic instability that occurred following the initial loading of DMED under supraclavicular BPB.A healthy 29-year-old man without any medical history showed profound bradycardia after receiving a loading dose of DMED 0.9μg/kg for 9 *** administration was promptly stopped,and after receiving a second dose of atropine,the heart rate recovered.A 62-year-old woman with a history of cardiomyopathy became hypotensive abruptly,requiring the administration of inotrope and vasopressors after receiving a reduced loading dose of 0.5μg/kg for 10 *** of the recommended loading dose of DMED was administered due to the underlying heart ***-sed blood pressure was maintained despite the intravenous administration of *** continuous infusion of dopamine and norepinephrine,the vital signs were maintained within normal *** and vasopressor support was required for over 6 h after the initial loading dose of *** DMED administration following BPB could trigger hemodynamic instability in patients with decreased cardiac function as well as in healthy individuals.

关键词： Dexmedetomidine Brachial plexus block Profound bradycardia Complication Hypotension Instability Case report

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The parallel-plate resonator:An RF probe for MR and MRI studies over a wide frequency range

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Magnetic Resonance Letters 2023年第4期3卷 306-318页

作者： Andres ramírez Aguilera Kevin J.Sanders Gillian R.Goward Bruce *** UNB MRI Centre Department of PhysicsUniversity of New BrunswickFrederictonNew BrunswickE3B 5A3Canada Department of Chemistry McMaster UniversityHamiltonOntarioL8S 4L8Canada

We explore the use of the parallel-plate resonator for the study of thin cuboid samples over a wide range of magnetic resonance *** parallel-plate resonator functions at frequencies from tens to hundreds of *** parallel-plate resonators are presented and discussed in a frequency range from 8 to 500 *** resonance experiments were performed on both horizontal and vertical bore magnet systems with lithium and hydrogen ***-plate radiofrequency(RF)probes are easy to build and easy to *** and simulations showed good sensitivity of the parallel-plate RF probe geometry with a small decrease in sensitivity at higher frequencies.

关键词： Parallel-plate resonator Optimization Magnetic resonance/magnetic resonance imaging(MR/MRI) Batteries

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DFT and TD-DFT Calculations of Orbital Energies and Photovoltaic Properties of Small Molecule Donor and Acceptor Materials Used in Organic Solar Cells

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Journal of Renewable Materials 2022年第10期10卷 2553-2567页

作者： Daniel Dodzi Yao Setsoafia Kiran Sreedhar ram Hooman Mehdizadeh-Rad David Ompong Vinuthaa Murthy Jai Singh College of Engineering IT and EnvironmentPurple 12Charles Darwin UniversityDarwinNT 0909Australia Energy and Resources Institute Charles Darwin UniversityDarwinNT 0909Australia

DFT and TD-DFT calculations of HOMO and LUMO energies and photovoltaic properties are carried out on four selected pentathiophene donor and one IDIC-4F acceptor molecules using B3LYP and PBE0 functionals for the ground state energy calculations and CAM-B3LYP functional for the excited state *** discrepancy between the calculated and experimental energies is reduced by correlating them with a linear *** fitted energies of HOMO and LUMO are used to calculate the Voc of an OSC based on these donors and acceptor blend and compared with experimental *** the Scharber model the calculated PCE of the donor-acceptor molecules agree with the *** has been found that fluorine substitution can be used to improve charge transport by reducing the electron and hole reorganization energies of the *** is also found that the introduction of fluorine onto the donor pentathiophene unit of the donor molecule results in a change of polarity of the distributed charges in the molecule due to the high electronegativity of the fluorine *** quantum chemical potential(μ),chemical hardness(η)and electronegativity(χ),and electrostatic potential maps(EPMs)are also calculated to identify different charge distribution regions in all five molecules.

关键词： Acceptor donor DFT excitons HOMO LUMO small molecule electrophilic nucleophilic and reorganization energy

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Dietary carbohydrate-to-protein ratio influences growth performance,hepatic health and dynamic of gut microbiota in atlantic salmon(Salmo salar)

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Animal Nutrition 2022年第3期10卷 261-279页

作者： Alejandro Villasante Carolina ramírez Hector Rodríguez Patricio Dantagnan Adrian Hernandez Elías Figueroa Jaime Romero Facultad de Medicina Veterinaria y Agronomía Universidad de Las AmericasSantiagoChile Laboratorio de Biotecnología de Alimentos Unidad de AlimentosInstituto de Nutricion y Tecnología de Los Alimentos(INTA)Universidad de ChileSantiagoChile Programa de Anatomía y Biología Del Desarrollo Facultad de MedicinaUniversidad de ChileSantiagoChile Núcleo de Investigacion en Produccion Alimentaria Facultad de Recursos NaturalesUniversidad Catolica de TemucoTemucoChile

Atlantic salmon(Salmo salar)fed a carbohydrate-rich diet exhibit suboptimal growth performance,along with other metabolic *** is well known that gut microbes play a pivotal role in influencing metabolism of the host,and these microbes can be modified by the *** main goal of the present study was to determine the effect of feeding graded levels of digestible carbohydrates to Atlantic salmon on the distal intestine digesta microbiota at 3 sampling times(i.e.,weeks 4,8 and 12),during a 12-week trial.A low carbohydrate-to-high protein diet(LC/HP,0%wheat starch),a medium carbohydrate-tomedium protein diet(MC/MP,15%wheat starch)or a high carbohydrate-to-low protein diet(HC/LP,30%wheat starch)was fed to triplicate fish tanks(27 to 28 fish per tank).We performed an in-depth characterization of the distal intestine digesta ***,growth parameters,liver histology and the expression of genes involved in hepatic neolipogenesis in fish were *** fed a HC/LP diet showed greater hepatosomatic and viscerosomatic indexes(P=0.026 and P=0.018,respectively),lower final weight(P=0.005),weight gain(P=0.003),feed efficiency(P=0.033)and growth rate(P=0.003)compared with fish fed the LC/HP ***,feeding salmon a high digestible carbohydrate diet caused greater lipid vacuolization,steatosis index(P=0.007)and expression of fatty acid synthase(fas)and delta-6 fatty acyl desaturase(d6fad)(P=0.001 and P=0.001,respectively)in the liver compared with fish fed the LC/HP ***,the major impact of feeding a carbohydrate-rich diet to Atlantic salmon in beta diversity of distal intestine digesta microbiota was observed at week 4(HC/LP vs MC/MP and HC/LP vs LC/HP;P=0.007 and P=0.008,respectively)and week 8(HC/LP vs MC/MP;P=0.04),no differences between experimental groups were detected after 12 weeks of ***,at the end of the trial,there was a negative correlation between lactic acid bacteria(LAB)members,including Leuconostoc and Lactobacil

关键词： Microbiota Microbiome Atlantic salmon Steatosis Lactic acid bacteria Probiotics

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Analysing the relationship between drought and soil erosion using vegetation health index and RUSLE models in Godavari middle sub-basin,India

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Geoscience Frontiers 2022年第2期13卷 21-33页

作者： Md Masroor Haroon Sajjad Sufia Rehman Roshani Singh Md Hibjur Rahaman Mehebub Sahana Raihan Ahmed ram Avtar Department of Geography Faculty of Natural SciencesJamia Millia IslamiaNew DelhiIndia School of Environment Education and Development(SEED)University of ManchesterUnited Kingdom Graduate School of Environment Earth Science Hokkaido UniversityJapan

Drought is a natural phenomenon posing severe implications for soil,groundwater and agricultural *** has been recognized as one of the most pervasive global change drivers to affect the *** being a weakly renewable resource takes a long time to form,but it takes no time to ***,the response of soil to drought conditions as soil loss is not manifested in the existing ***,this study makes a concerted effort to analyze the relationship between drought conditions and soil erosion in the middle sub-basin of the Godavari River in *** remote sensing data was utilized for driving drought indices during ***,we constricted Temperature condition index(TCI)and Vegetation Condition Index(VCI)from Land Surface Temperature(LST)and Enhanced Vegetation Index(EVI)derived from MODIS *** and VCI were then integrated to determine the Vegetation Health Index(VHI).Revised Universal Soil Loss Equation(RUSLE)was utilized for estimating soil *** relationship between drought condition and vegetation was ascertained using the Pearson *** of the northern and southern watersheds experienced severe drought condition in the sub-basin *** mean frequency of the drought occurrence was 7.95 *** average soil erosion in the sub-basin was estimated to be 9.88 t ha^(-1)year^(-1).A positive relationship was observed between drought indices and soil erosion values(r value being 0.35).However,wide variations were observed in the distribution of spatial *** various factors,the slope length and steepness were found to be the main drivers of soil erosion in the ***,the study calls for policy measures to lessen the impact of drought and soil erosion.

关键词： Drought vulnerability Soil erosion RUSLE Vegetation Health Index(VHI) Godavari middle sub-basin

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Twenty-four-hour movement guidelines during middle adolescence and their association with glucose outcomes and type 2 diabetes mellitus in adulthood

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Journal of Sport and Health Science 2023年第2期12卷 167-174页

作者： Antonio García-Hermoso JoséFrancisco López-Gil Yasmin Ezzatvar Robinson ramírez-Vélez Mikel Izquierdo Navarrabiomed Hospital Universitario de Navarra(HUN)Universidad Publica de Navarra(UPNA)IdiSNAPamplona 31008Spain Health and Social Research Center Universidad de Castilla-La ManchaCuenca 16007Spain Department of Nursing Universitat de ValenciaValencia 46010Spain

Purpose:The aim of the present study was to determine the association between adherence to the 24-h movement guidelines during middle adolescence and glucose outcomes(glycated hemoglobin and fasting glucose)and type 2 diabetes mellitus(T2DM)in adulthood,14 and 22 years ***:We analyzed data from apparently healthy adolescents aged 12-18 years who participated in WavesⅠandⅡ(1994-1996,n=14,738),WaveⅣ(2008-2009,n=8913),and Wave V(2016-2018,n=3457)of the National Longitudinal Study of Adolescent to Adult Health(Add Health)in the United *** activity,screen time,and sleep duration were measured using questionnaires,and the 24-h guidelines were defined as:5 or more times moderate-to-vigorous physical activity per week,≤2 h per day of screen time,and 9-11 h of sleep for 12-13 years and 8-10 h for 14-17 *** and venous whole blood was collected and analyzed to determine glycated hemoglobin and fasting glucose for WavesⅣandⅤ,***:Only 2.1%of the adolescents met all the 3 guidelines,and 37.8%met none of *** both wavesⅣandⅤ,adolescents who met physical activity and screen time guidelines had lower odds of T2DM in adulthood than those who did not meet any of these guidelines(WaveⅣ;prevalence ratio(PR)=0.57,95%confidence interval(95%CI):0.21-0.89;Wave V:PR=0.43,95%CI:0.32-0.74).Only for Wave V did adolescents who met all 3 guidelines have lower odds of T2DM at follow-up compared with those who did not meet any of these guidelines(PR=0.47,95%CI:0.24-0.91).Also,for each increase in meeting one of the 24-h recommendations,the odds of T2DM decreased by 18%(PR=0.82,95%CI:0.61-0.99)and 15%(PR=0.85,95%CI:0.65-0.98)in adulthood for WavesⅣandⅤ,***:Promoting all 24-h movement guidelines in adolescence,especially physical activity and screen time,is important for lowering the potential risk of T2DM in adulthood.

关键词： Glucose metabolism Glycated hemoglobin Physical activity Screen time Sleep duration

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