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世界感染杂志 2006年第6期6卷 576-576页

作者： Guardiola M Ferre R salazar J Clin Chem 欧强（摘）张友祥（校）不详上海市（复旦大学附属）公共卫生中心上海201508

伴随高效抗反转录病毒治疗（包含蛋白酶抑制剂）相关高脂血症能加速动脉粥样硬化的形成。能影响极低密度脂蛋白产生和降解的载脂蛋白A—V（APOA5）基因在蛋白酶抑制剂诱导的高脂血症中起着重要的作用，尤其是在那些发生APOA5-1131T-〉C... 详细信息

伴随高效抗反转录病毒治疗（包含蛋白酶抑制剂）相关高脂血症能加速动脉粥样硬化的形成。能影响极低密度脂蛋白产生和降解的载脂蛋白A—V（APOA5）基因在蛋白酶抑制剂诱导的高脂血症中起着重要的作用，尤其是在那些发生APOA5-1131T-〉C基因型变化的病人中。作者检测了229名HIV感染者5年脂蛋白变化情况。为了进行统计分析。作者根据服用蛋白酶抑制剂和APOA5—1131T-〉C基因型改变将所有病人进行分类。结果发现HIV感染者的频率是0．08。与普通人群相似。

关键词：蛋白酶抑制剂 HIV感染者载脂蛋白A 脂代谢异常因变量极低密度脂蛋白动脉粥样硬化

Vocational Training and Basic Knowledge of the Mexican University Coach

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Journal of Sociology Study 2015年第3期5卷 232-244页

作者： Ciria Margarita salazar Julio Alejandro Gomez Figueroa Martha Patricia Perez Lopez CarmenSilvia Vargas Pena Pedro Julian Flores Moreno Rossana Tamara Medina Valencia Jose E. Del RioValdivi Jose Aldo Hernandez-Murua University of Colima Mexico University of Veracruz Mexico Autonomous University of Sinaloa Mexico

This paper shows an overview of the academic and vocational training of the Mexican university coaches. Professional sports in Mexico are not sufficiently organized in all disciplines and the Olympic sporting system does not consider the university sports as a hotbed of world‐class athletes. Coaches" academic and vocational training is one of the variables to analyze university‐sporting level. A quantitative model was used to approach the topic through an adapted and validated version of a questionnaire used in Spanish populations. The sample consisted of 326 participant"s coaches at the 2013 national Student Games. Among the findings, observed there are some aspects revealed related to the training, the domain of knowledge and the existing relationship between an empirical coach and a trained one. In conclusion, therefore, it is important to emphasize that the non‐skilled trainer finds it difficult to achieve the optimum sport development, the fulfillment of the assigned tasks, the selection, the dosage, the linking of different means, and the assessment of achievement. According to the national sport level, the university trainer"s profile neither allows the consolidation of practice nor these ages and sport levels.

关键词：职业培训教练员墨西哥大学知识体育运动运动系统奥林匹克

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利用可自动灌溉的雾化栽培系统种植芝麻作物

农业工程技术 2020年第33期40卷 88-88页

作者： Jhon D.Ríos salazar John E.Candelo-Becerra Fredy E.Hoyos Velasco 国立哥伦比亚大学科学学院物理系国立哥伦比亚大学电能自动化系

介绍了一种利用可灌溉雾化栽培系统自动控制种植芝麻作物的有效方式。该系统采用一个可重新编程的电子电路,使用软件生成不同的灌溉周期,以获得芝麻作物的充分生长。结果表明,在试验期间,温室中生长的样品与田间生长的样品具有相同的生... 详细信息

介绍了一种利用可灌溉雾化栽培系统自动控制种植芝麻作物的有效方式。该系统采用一个可重新编程的电子电路,使用软件生成不同的灌溉周期,以获得芝麻作物的充分生长。结果表明,在试验期间,温室中生长的样品与田间生长的样品具有相同的生长行为。通过连续循环灌溉35天,可以获得更高效、更持久的五周产量,以供应消费者。所分析的不同植物的叶片生长和数量均保持一致。根系生长状况相似,只是其中一些在五周内表现出大小差异。

关键词：雾化栽培芝麻作物粮食生产灌溉系统智能系统

患Fabry病的幼儿早期脑微血管病变的放射学证据

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世界核心医学期刊文摘（儿科学分册） 2005年第12期1卷 35-35页

作者： Cabrera-salazar M.A. O'Rourke E. Charria- Ortiz G. Barranger J.A. 郭战宏 University of Pittsburgh Department of Human Gentics E1650 Biomedical Science Tower Pittsburgh PA 15261 United StatesDr.

We report on 2 children with Fabry disease who had radiologic evidence of microvascular central nervous system involvement despite the clinical absence of renal, cardiac, or cerebral manifestations. This suggests that treatment with enzyme replacement therapy may be necessary early in the disease to avoid irreversible complications.

关键词： Fabry病脑微血管中枢神经系统疾病早期

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nature:寨卡病毒导致小鼠睾丸体积缩小、结构破坏

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现代生物医学进展 2017年第6期17卷 I0001-I0001页

作者： Jennifer Govero, Justin M. Richner, Elizabeth A. Caine, Vanessa salazar Michael S. Diamond Prabagaran Esakky, Suzanne M. Scheaffer, Andrea Drury Kelle H. Moley Estefania Fernandez, Matthew J. Gorman Michael S. Diamond Derek J. Platt Michael S. Diamond Kelle H. Moley Michael S. Diamond Department of Medicine Washington University School of Medicine Saint Louis Missouri 63110 USA Department of Obstetrics and Gynecology Washington University School of Medicine Saint Louis Missouri 63110 USA Department of Pathology and Immunology Washington University School of Medicine Saint Louis Missouri 63110 USA Department of Molecular Microbiology Washington University School of Medicine Saint Louis Missouri 63110 USA Department of Cell Biology and Physiology Washington University School of Medicine Saint Louis Missouri 63110 USA The Center for Human Immunology and Immunotherapy Programs Washington University School of Medicine Saint Louis Missouri 63110 USA

大部分针对寨卡病毒（Zika Virus）的研究发现。寨卡病毒感染的影响主要集中在孕妇和出生缺陷。但在小鼠中。新的研究发现了寨卡病毒对于小鼠雄性生殖系统的严重损伤，引起了人们对人类男性可能遭受得到的威胁的严重关切。美国华盛顿大... 详细信息

大部分针对寨卡病毒（Zika Virus）的研究发现。寨卡病毒感染的影响主要集中在孕妇和出生缺陷。但在小鼠中。新的研究发现了寨卡病毒对于小鼠雄性生殖系统的严重损伤，引起了人们对人类男性可能遭受得到的威胁的严重关切。美国华盛顿大学医学院的研究人员们，通过在《nature》上的研究文章，报道了寨卡病毒对于雄性小鼠的生殖系统的损害。

关键词：病毒感染雄性小鼠睾丸体积结构破坏《nature》雄性生殖系统华盛顿大学出生缺陷

Expression of Multidrug Resistance ATP-Binding Cassette(ABC)Transporters in Canine Mammary Tumors

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Advances in Breast Cancer Research 2015年第3期4卷 77-85页

作者： Breno S.Salgado Suely nonogaki Luisa M.Soares Angela Akamatsu Cristiano R.n.da Silva Thiago P.Anacleto Rodolfo Malagó Rafael M.Rocha Fátima Gartner noeme S.Rocha Departamento de Patologia Faculdade de Medicina de BotucatuUniversidade Estadual PaulistaCampus de BotucatuBotucatuBrazil Instituto de Ciências Biomédicas Abel salazar Universidade do Porto(Intitute of Biomedical Sciences Abel Salazar of University of Porto)OportoPortugal Fundacao Antonio Prudente Hospital A.C.CamargoSao PauloBrazil Departamento de Clínica Veterinária Faculdade de Medicina Veterinária e ZootecniaUniversidade Estadual PaulistaUNESP.BotucatuBrazil Hospital Escola de Medicina Veterinária Fundacao de Ensino e Pesquisa de Itajubá—FEPIItajubáBrazil

Mammary neoplasms are the most common tumors in female dogs. They are usually treated using solely surgical mastectomy—which is recognized as unsatisfactory in many cases. Given this, the benefits of chemotherapy in dogs with mammary cancer need to be further explored. Some drugs that can be used for treating canines with mammary tumors may be substrates of uptake and/or efflux transporters such as the ATP-binding cassette (ABC) transporters. Unfortunately, very little is known regarding the pathobiology of such proteins in canine tumors, including mammary cancer. Accordingly, this study was designed to characterize the expression of ABC transporters P-glycoprotein, MRP1, and MRP2 and their relation with clinicopathologic factors in order to allow a better understanding of their influence in canine mammary cancer. P-glycoprotein was expressed in tumors from 55.8% of patients, while MRP1 and MRP2 were expressed in 37.2% and 39.5% of tumors, respectively. P-glycoprotein expression showed to be related with regional lymph node spread (P = 0.0038), as well as with tumor grade (P = 0.0353) and with a shorter survival (P = 0.0245). MRP1 revealed a strong association with a higher histological grade (P nd overall survival (P = 0.0002). Additionally, MRP1 was determined as prognostic indicator independent of lymph node status using Cox proportional-hazards regression multivariate analysis (P = 0.0216). no relations between MRP2 and clinicopathologic features were observed. We have found that P-glycoprotein and MRP1 are expressed in highly aggressive canine mammary tumors and are related with poor prognosis. Our results suggest that they may play a significant role in the course of canine mammary cancer progression and be promising candidate markers for a validation study on therapy outcome.

关键词： MDR1 P-Gp MRP1 MRP2 ABCC2 Mammary neoplasms Prognosis Dog

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史密森南广场园区规划

城市环境设计 2019年第2期118卷 160-169页

作者： Aaron Hales Alana Goldweit Alexandre Hamlyn Andriani Atmadja Annette Miller Benjamin Dinapoli Benjamin novacinski Cadence Bayley Choonghyo Lee Chris Falla Daisy Zhong Daniele Pronesti Doug Stechschulte Emily Chen Gabriel Hernandez Solano Janice Rim Jennifer Shen Jeremy Alain Siegel Jihoon Hyun Julian Andres Ocampo salazar Kalina Pilat Katarzyna Starczewska Lina Bondarenko Mahsa Malek Manon Otto Martin Voelkle Ola Hariri Otilia Pupezeanu Saecheol Oh Sara Ibrahim Stephen Kwok Stephen Steckel Suemin Jeon Tammy Teng Taylor Fulton Tianqi Zhang Vincent Fulia Wells Barber Wesley Chiang Zhifei Xu 陈子钰

通过与史密森学会、当地居民以及决策者的密切合作,我们为南广场园区制定了总体规划,作为对旧与新的重新诠释——方案利用园区内的现有元素,在严格监管与历史保护的限制中寻求自由。该提案旨在提升并扩大游客服务和教育空间,在博物馆与... 详细信息

通过与史密森学会、当地居民以及决策者的密切合作,我们为南广场园区制定了总体规划,作为对旧与新的重新诠释——方案利用园区内的现有元素,在严格监管与历史保护的限制中寻求自由。该提案旨在提升并扩大游客服务和教育空间,在博物馆与花园之间建立清晰的入口和联系,并取代已达到使用寿命的老化建筑机械系统。与此同时,团队致力于保留豪普

关键词：园区规划总体规划 Avenue 史密森史密森学会基础隔震弗里尔交通流线

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79&PARK住宅区

城市环境设计 2019年第2期118卷 198-209页

作者： H?gni Laksáfoss Agata Wozniczka Agne Tamasauskaite Alberto Herzog Borko nikolic Christin Svensson Claudio Moretti Dominic Black Eva Seo-Andersen Frederik Wegener Gabrielle nadeau Jacob Lykkefold Aaen Jaime Peiro Suso Jan Magasanik Jesper Boye Andersen Jonas Aars? Larsen Julian Andres Ocampo salazar Karl Johan nyqvist Karol Bogdan Borkowski Katarina Mácková Katrine Juul Kristoffer negendahl Lucian Racovitan Maria Teresa Fernandez Rojo Max Gabriel Pinto Min Ter Lim narisara Ladawal Schr?der Romea Muryn Ryohei Koike Sergiu Calacean Song He Taylor Mcnally-Anderson Terrence Chew Thomas Sebastian Krall Tiago Sá Tobias Vall? S?rensen Tore Banke Laurian Ghinitoiu 朱翰林

位于G?rdet国家公园边缘,Kullen有意识地塑造了一个尊重且适应环境的形式,并展现出与众不同的社区和壮丽的景色。为直接回应周围环境,建筑的西北和东南角高起至临近周边的高度;而距离公园最远、且本是视野最不好的东北角被拉高以使其拥... 详细信息

位于G?rdet国家公园边缘,Kullen有意识地塑造了一个尊重且适应环境的形式,并展现出与众不同的社区和壮丽的景色。为直接回应周围环境,建筑的西北和东南角高起至临近周边的高度;而距离公园最远、且本是视野最不好的东北角被拉高以使其拥有公园和港口最壮阔的景色。建筑西南角延伸至最远处的G?rdet国家公园;为了在建筑和自然之间创造一个人性化的柔和边缘,西南角被尽可能地压低,变成

关键词：住宅区