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Endoscopic debridement for non-insertional Achilles tendinopathy with and without platelet-rich plasma

Journal of Sport and Health Science 2023年第2期12卷 275-280页

作者： Hajo Thermann ralph Fischer Nikolaos Gougoulias Lucio Cipollaro Nicola Maffulli HKF-International Center for Hip Foot and Knee SurgeryBismarckstrae 9-1569115 HeidelbergGermany Footsurgery Clinic 54631 ThessalonikiGreece Department of Musculoskeletal Disorders Faculty of Medicine and SurgeryUniversity of SalernoSalerno 89100Italy Department of Medicine Surgery and DentistryUniversity of SalernoVia S.Allende84081 Baronissi(SA)Italy Centre for Sports and Exercise Medicine Barts and The London School of Medicine and DentistryMile End Hospital275 Bancroft RoadLondon E14DGQueen Mary University of LondonLondonUK School of Pharmacy and Bioengineering Keele University Faculty of MedicineThornburrow DriveStoke on TrentST47QBUK

Background:When non-operative management fails to improve symptoms in patients with non-insertional Achilles tendinopathy,surgery may be *** open and endoscopic techniques have been proposed,and platelet-rich plasma(PRP)injections have been proposed as an adjunct to aid tendon ***:Thirty-six patients with mid-portion Achilles tendinopathy were randomized to undergo endoscopic debridement alone(n=19)or in combination with intraoperative PRP application(n=17).Clinical outcome measures included the Visual Analogue Scale for pain,function,and satisfaction and the Victorian Institute of Sports Assessment-Achilles(VISA-A)*** were followed-up at 6 weeks,3months,6 months,and 12 months after *** MRI examination at 3 and 12 months was used to assess signal alterations within the ***:Both groups showed significant clinical improvement(p<0.05)after surgery,with no difference between the 2 *** diameter increased at 3 months and decreased at 12 *** tendinopathy area increased at 3 months and decreased at 12 months below baseline level in both *** was no significant difference between the groups regarding the MRI *** thickening and MRIdetected signal alteration persisted after surgery,with no association between imaging and clinical *** minor complications were reported:2 in the PRP group and 3 in the control ***:Endoscopic debridement of the Achilles tendon improved clinical outcomes in patients with mid-portion *** addition of PRP did not improve outcomes compared to debridement *** parameters showed no association with clinical outcomes.

关键词： Achilles tendon Endoscopic Non-insertional PRP Tendinopathy

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CHLAMYDOMONAS SAJAO NOV. SP.(CHLOROPHYTA, VOLVOCALES)

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Journal of Oceanology and Limnology 1984年第1期2卷 92-96页

作者： ralph A.Lewin University of California La Jolla CA 92093 U S A

A new species of Chlamydomonas, namely, C. sajao nov. sp. of the Volvocales, Chlorophyta was isolated from a duckweed growing near a ricefield in the vicinity of Guangzhou, China. This interesting unicellular green alga, similar to C. mexicana from Mexico, secretes quantities of extracellular mucilaginous polysaccharides, and may be employed in improving soil quality. The new species resembles C. waldenburgensis Moewus in most characteristics but differs in three important features.

关键词： SP CHLOROPHYTA VOLVOCALES CHLAMYDOMONAS SAJAO NOV

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The Involvement of Lipids in Alzheimer's Disease

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Journal of Genetics and Genomics 2014年第5期41卷 261-274页

作者： Wei Ling Florence Lim Ian James Martins ralph Nigel Martins School of Medical Sciences Edith Cowan University Centre of Excellence in Alzheimer's Disease Research and Care McCusker Foundation for Alzheimer's Disease Research Inc. Suite 22 Hollywood Medical Centre School of Psychiatry and Clinical Neurosciences The University of Western Australia

It has been estimated that Alzheimer＇s disease （AD）, the most common form of dementia, will affect approximately 81 million individuals by 2040. To date, the actual cause and cascade of events in the progression of this disease have not been fully determined. Furthermore, there is currently no definitive blood test or simple diagnostic method for AD. Considerable efforts have been put into proteomic approaches to develop a diagnostic blood test, but to date these efforts have not been successful. More recently, there has been a stronger focus on lipidomic studies in the hope of increasing our understanding of the underlying mechanisms leading to AD and developing an AD blood test. It is well known that the strongest genetic risk factor for AD is the e4 variant of apolipoprotein E （APOE）. Evidence suggests that the ApoE protein, a major lipid transporter, plays a key role in the pathogenesis of AD, and its role in both normal and aberrant lipid metabolism warrants further extensive investigation. Here, we review ApoE-lipid interactions, as well as the roles that lipids may play in the pathogenesis of AD.

关键词： Alzheimer's disease Lipids ApoE Oxysterols Inflammation

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On low-pass digital filters in oceanography

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Acta Oceanologica Sinica 1993年第2期12卷 183-196页

作者： Wang Jin ralph T.Cheng Institute of Oceanology Academia SinicaQingdao 266071China Department of Meteorology McGill University805 Sherbrook Street WestMontrealQuebec H3A 2K6Canada U.s.Geological Survey Menlo ParkCa 94025 USA

Two types of filters are widely used to remove semidirunal and diurnal tidal signals and other high frequency noises in *** first type of filters uses moving average with weights in time domain,and can be easily *** data will be lost at each end of the time series,especially for the low low-pass *** second type of filters uses the discrete Fourier transform filter(DFTF)which operates in the frequency domain,and there are no data loss at the ends for the forward ***,owing to the Gibbs phenomenon and the discrete sampling(Nyquist effect),ringing appears in the inverse transformed data,which is especially serious at each *** some data at the ends are also *** present study tries to find out what causes the ringing and then to seek for methods to overcome the *** have found that there are two kinds of ringings,one is the Gibbs phenomenon,as defined *** other is the'Nyquist'ringing due to sampling Nyquist critical *** former is due to the abrupt transition in frequency *** Gibbs and Nyquist effects show the ringing at each end of the filtered time ***,the use of a cosine taper or a linear taper on the window in the frequency domain makes the transition band smooth,so that the Gibbs phenomenon will be *** applying the Fast Fourier Transform(FFT),the original time series at each end is properly tapered by a split cosine bell that reduces significant ringing since this method limits the energy transfer from outside of the Nyquist ***,the DFTF can be a powerful tool to suppress the signals in which we are not interested,with sharp peaks in low frequency variation and less data loss at each end.

关键词： data On low-pass digital filters in oceanography

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Enhanced oil recovery of low salinity water flooding in sandstone and the role of clay

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Petroleum Exploration and Development 2018年第5期45卷 927-931页

作者： Al-SAEDI Hasan N FLORI ralph E Missouri University of Science and Technology

Sandstone core and free-clay sandstone core were prepared in chromatography columns, and core flooding experiments were performed to determine the EOR mechanisms of low salinity（LS） water flooding and analyze the effect of clay on recovery factor. First, brine with a high salinity（HS） of 100 000 mg/L was injected to simulate formation water. Then, LS water of 1 000 mg/L was then injected at different temperatures. Concentrations of Ca;and CH;COO;and pH of the fluid flowing out of the chromatography column were recorded. The results showed that during flooding the free-clay core with LS water, the carboxylic acid detached from the sand, as great as that of the clay-containing cores. It showed a noteworthy desorption of Ca;from the free-clay core surface, which indicated that LS water flooding resulted in a high recovery in sandstone without clay. Compared with HS water flooding, in the LS water flooding, the p H of produced fluid increased significantly; also, as the temperature increased, the pH and Ca;concentration of the produced fluid decreased; and the hydrophilic property of the sandstone was stronger. The results of oil recovery tests using the same columns were in line with the chemical analyses. The oil recovery from the free-clay columns was as great as from the column clay-containing column. The results of wettability measurements supported our theory.

关键词： sandstone reservoir low salinity water flooding enhanced oil recovery water-rock reaction wettability alteration clay

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The Chlamydomonas Chloroplast HLP Protein Is Required for Nucleoid Organization and Genome Maintenance

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Molecular Plant 2009年第6期2卷 1223-1232页

作者： Daniel Karcher Dietrich Koster Anne Schadach Anja Klevesath ralph Bock Max-Planck-lnstitut fur Molekulare Pflanzenphysiologie Am Muhlenberg 1 D-14476 Potsdam-Golm Germany

The chloroplasts genome （plastome） occurs at high copy numbers per cell. Several chloroplast genome copies are densely packed into nucleoprotein particles called nucleoids. How genome packaging occurs and which proteins organize chloroplast nucleoids are largely unknown. Here, we have analyzed the Chlamydornonas reinhardtii homolog of the bacterial architectural DNA-binding protein HU, the histone-like protein HLP. We show that the Chlarnydornonas HLP protein is targeted to chloroplasts and associates with nucleoids. Knockdown of HLP gene expression by RNA interference （RNAi） alters the structure of chloroplast nucleoids and appears to reduce the level of compaction of chloroplast DNA. Unexpectedly, also chloroplast genome copy numbers are significantly decreased in the RNAi strains, suggesting that, in addition to its architectural role in nucleoid formation, the HIP protein is also involved in chloroplast genome maintenance.

关键词： Chloroplast nucleoid Chlamydomonas reinhardtii HLP DNA-binding protein genome maintenance

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Improving Shape from Shading with Interactive Tabu Search

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Journal of Computer Science & Technology 2016年第3期31卷 450-462页

作者： Jing Wu Paul L. Rosin Xianfang Sun ralph R. Martin School of Computer Science and Informatics Cardiff University Cardiff CF24 3AA U.K.

Optimisation based shape from shading （SFS） is sensitive to initialization： errors in initialization are a signifi- cant cause of poor overall shape reconstruction. In this paper, we present a method to help overcome this problem by means of user interaction. There are two key elements in our method. Firstly, we extend SFS to consider a set of initializations, rather than to use a single one. Secondly, we efficiently explore this initialization space using a heuristic search method, tabu search, guided by user evaluation of the reconstruction quality. Reconstruction results on both synthetic and real images demonstrate the effectiveness of our method in providing more desirable shape reconstructions.

关键词： shape from shading user interaction tabu search

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AN IMPROVED METHOD FOR AN ECO-CLIMATIC ZONATION AND ITS APPLICATION AS ZONES IN ARID GRASSLANDS,SEMIDESERTS AND DESERTS

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干旱区资源与环境 1993年第Z1期7卷 100-103页

作者： ralph Jaetzold Univ.of Trier Germany

The method was developed for a Range Management Handbook of Kenya and the pre-liminary results published 1991. Now it is improved to a stage ready for international discus-sion.1. Main moisture Zones are defined by a ... 详细信息

关键词： Eco-Climatic Zonation Arid Grassland Semidesert Desert Pastro-Ecoclimatic Zone

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Teach Yourself the Basics of Aspen Plus 1

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2011年

作者： Schefflan ralph

ISBN: (数字)9780470910047

ISBN: (纸本)9780470910047

Aspen Plus is on of the most popular process simulation software programs used industrially and academically. Though the software is available at many corporations and universities, there are no textbooks which are dedicated to teaching the step-by-step use of the software. This book is designed to fill that need. The structure of the book is unique in that it emulates a lecture /workshop classroom *** chapter starts with the equivalent of a classroom lecture followed by workshops which provide experience in the chapter's subject matter. The enclosed CD contains solutions, both in Aspen Plus and text formats, to examples imbedded in the text as well as to all the workshops. There are also notes at the end of each chapter designed to aid readers that have difficulty with the ***: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.

关键词： guide stepbystep aspen basics scientific plus important wide variety software aspen plus design conceptual tool performance chemical processes years industrially academically powerful engineering popular

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Comparative studies on storage cells in tardigrades during starvation and anhydrobiosis

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Current Zoology 2010年第2期56卷 259-263页

作者： Andy REUNER Steffen HENGHERR Franz Brümmer ralph O.SCHILL Universitt Stuttgart Biological Institute Zoology UniversittStuttgart Biological Institute Zoology

The impact of starvation and anhydrobiosis on the number and size of the storage cells in the tardigrade species Milnesium tardigradum, Paramacrobiotus tonollii and Macrobiotus sapiens was investigated to gain more insight on the energetic side of anhydrobiosis. Storage cells are free floating cells within the body cavity of tardigrades and are presumed to store and release energy in form of glycogen, protein and fat to maintain a constant nutrient regime for the other tissues. The body size of the animals was not correlated with the size of the storage cells, however, M. tardigradum the largest species analysed also had the largest storage cells. A reduction in the size of the storage cells is apparent in all three species after seven days of starvation. A seven-day period of anhydrobiosis leads to a decrease in cell size in M. tardigradum but not in P. tonollii and M. sapiens. Although M. sapiens was raised on green algae, and M. tardigradum and P. tonollii were fed with rotifers and nematodes this difference in nourishment was not reflected in the response of the storage cells to anhydrobiosis

关键词： Tardigrada cryptobiosis Milnesium tardigradum Paramacrobiotus tonollii Macrobiotus sapiens

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