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mental health status among COVID-19 patients survivors of critical illness in Saudi Arabia:A 6-month follow-up questionnaire study

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World Journal of Clinical Cases 2024年第15期12卷 2560-2567页

作者： Abdullah m Alhammad Namareq F Aldardeer Abdulaziz alqahtani mohammad H Aljawadi Bushra Alnefaie Raghad Alonazi mansour Almuqbil Abdulrahman Alsaadon rakan m.alqahtani Rashid Alballaa Bader Alshehri mohammed I Alarifi Fahad D Alosaimi Department of Clinical Pharmacy College of PharmacyKing Saud UniversityRiyadh 12372Saudi Arabia Department of Pharmacy Services King Faisal Specialist Hospital and Research CentreJeddah 21499Saudi Arabia Corporate Department of Pharmacy Services King Saud University Medical CityRiyadh 12372Saudi Arabia College of Pharmacy King Saud UniversityRiyadh 12372Saudi Arabia Department of Critical Care medicine College of MedicineKing Saud UniversityRiyadh 12372Saudi Arabia Department of Psychiatry College of MedicineKing Saud UniversityRiyadh 12372Saudi Arabia

BACKGROUND Psychological assessment after intensive care unit(ICU)discharge is increasingly used to assess patients'cognitive and psychological ***,few studies have examined those who recovered from coronavirus disease 2019(COVID-19).There is a paucity of data from the middle East assessing the post-ICU discharge mental health status of patients who had *** To evaluate anxiety and depression among patients who had severe *** This is a prospective single-center follow-up questionnaire-based study of adults who were admitted to the ICU or under ICU consultation for>24 h for *** patients were contacted via *** patient’s anxiety and depression six months after ICU discharge were assessed using the Hospital Anxiety and Depression Scale(HADS).The primary outcome was the mean HADS *** secondary outcomes were risk factors of anxiety and/or *** Patients who were admitted to the ICU because of COVID-19 were screened(n=518).Of these,48 completed the *** mean age was 56.3±17.2 *** patients(62.5%)were *** main comorbidities were endocrine(n=24,50%)and cardiovascular(n=21,43.8%)*** mean overall HADS score for anxiety and depression at 6 months post-ICU discharge was 11.4(SD±8.5).A HADS score of>7 for anxiety and depression was detected in 15 patients(30%)and 18 patients(36%),*** from the multivariable ordered logistic regression demonstrated that vasopressor use was associated with the development of anxiety and depression[odds ratio(OR)39.06,95% confidence interval:1.309-1165.8;Pmonths after ICU discharge,30% of patients who had COVID-19 demonstrated a HADS score that confirmed anxiety and *** compare the psychological status of patients following an ICU admission(with vs without COVID-19),further studies are warranted.

关键词： COVID-19 Critically ill Anxiety Depression HADS Saudi Arabia

DNBP-CCA:A Novel Approach to Enhancing Heterogeneous Data Traffic and Reliable Data Transmission for Body Area Network

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Computers, materials & Continua 2024年第5期79卷 2851-2878页

作者： Abdulwadood Alawadhi mohd.Hasbullah Omar Abdullah Almogahed Noradila Nordin Salman A.alqahtani Atif m.Alamri InterNetWorks Research Laboratory School of ComputingUniversiti Utara MalaysiaSintok06010Malaysia Faculty of Computer Science and Information Technology Universiti Tun Hussein Onn MalaysiaParit RajaJohor86400Malaysia School of Games&Creative Technology University for the Creative ArtsFarnhamGU97DSUK Computer Engineering Department College of Computer and Information SciencesKing Saud UniversityRiyadh11543Saudi Arabia Software Engineering Department College of Computer and Information SciencesKing Saud UniversityRiyadh11543Saudi Arabia

The increased adoption of Internet of medical Things (IomT) technologies has resulted in the widespread use ofBody Area Networks (BANs) in medical and non-medical domains. However, the performance of IEEE 802.15.4-based BANs is impacted by challenges related to heterogeneous data traffic requirements among nodes, includingcontention during finite backoff periods, association delays, and traffic channel access through clear channelassessment (CCA) algorithms. These challenges lead to increased packet collisions, queuing delays, retransmissions,and the neglect of critical traffic, thereby hindering performance indicators such as throughput, packet deliveryratio, packet drop rate, and packet delay. Therefore, we propose Dynamic Next Backoff Period and Clear ChannelAssessment (DNBP-CCA) schemes to address these issues. The DNBP-CCA schemes leverage a combination ofthe Dynamic Next Backoff Period (DNBP) scheme and the Dynamic Next Clear Channel Assessment (DNCCA)scheme. The DNBP scheme employs a fuzzy Takagi, Sugeno, and Kang (TSK) model’s inference system toquantitatively analyze backoff exponent, channel clearance, collision ratio, and data rate as input parameters. Onthe other hand, the DNCCA scheme dynamically adapts the CCA process based on requested data transmission tothe coordinator, considering input parameters such as buffer status ratio and acknowledgement ratio. As a result,simulations demonstrate that our proposed schemes are better than some existing representative approaches andenhance data transmission, reduce node collisions, improve average throughput, and packet delivery ratio, anddecrease average packet drop rate and packet delay.

关键词： Internet of medical Things body area networks backoff period tsk fuzzy model clear channel assessment media access control

New Antenna Array Beamforming Techniques Based on Hybrid Convolution/Genetic Algorithm for 5G and Beyond Communications

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Computer modeling in Engineering & Sciences 2024年第3期138卷 2749-2767页

作者： Shimaa m.Amer Ashraf A.m.Khalaf Amr H.Hussein Salman A.alqahtani mostafa H.Dahshan Hossam m.Kassem Electronics and Communications Engineering Department Higher Institute of Engineering and TechnologyKafr ElsheikhEgypt Electronics and Electrical Communications Engineering Department Faculty of EngineeringMinia UniversityMiniaEgypt Electronics and Electrical Communications Engineering Department Faculty of EngineeringTanta UniversityTantaEgypt Electronics and Electrical Communications Engineering Department Faculty of EngineeringHorus University EgyptNew DamiettaEgypt Department of Computer Engineering College of computer and Information SciencesKing Saud UniversityRiyadh11543Saudi Arabia School of Computing Mathematics and EngineeringCharles Sturt UniversityBathurstNSW2795Australia

Side lobe level reduction(SLL)of antenna arrays significantly enhances the signal-to-interference ratio and improves the quality of service(QOS)in recent and future wireless communication systems starting from 5G up to ***,it improves the array gain and directivity,increasing the detection range and angular resolution of radar *** study proposes two highly efficient SLL reduction *** techniques are based on the hybridization between either the single convolution or the double convolution algorithms and the genetic algorithm(GA)to develop the Conv/GA andDConv/GA,*** convolution process determines the element’s excitations while the GA optimizes the element *** m elements linear antenna array(LAA),the convolution of the excitation coefficients vector by itself provides a new vector of excitations of length N=(2m−1).This new vector is divided into three different sets of excitations including the odd excitations,even excitations,and middle excitations of lengths m,m−1,andm,*** the same element spacing as the original LAA is used,it is noticed that the odd and even excitations provide a much lower SLL than that of the LAA but with amuch wider half-power beamwidth(HPBW).While the middle excitations give the same HPBWas the original LAA with a relatively higher *** the increased HPBWof the odd and even excitations,the element spacing is optimized using the ***,the synthesized arrays have the same HPBW as the original LAA with a two-fold reduction in the ***,for extreme SLL reduction,the DConv/GA is *** this technique,the same procedure of the aforementioned Conv/GA technique is performed on the resultant even and odd excitation *** provides a relatively wider HPBWthan the original LAA with about quad-fold reduction in the SLL.

关键词： Array synthesis convolution process genetic algorithm(GA) half power beamwidth(HPBW) linear antenna array(LAA) side lobe level(SLL) quality of service(QOS)

Adherence to Advisory Committee on Immunization Practices in diabetes mellitus patients in Saudi Arabia:A multicenter retrospective study

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World Journal of Diabetes 2024年第3期15卷 440-454页

作者： Saleh Fahad Alqifari Aya K Esmail Dalal m Alarifi Ghalya Y Alsuliman maram m Alhati may R mutlaq mohammed Aldhaeefi Shaden A Alshuaibi Palanisamy Amirthalingam Abrar Abdallah Afaf S Wasel Heba R Hamad Shoroq Alamin Tasneem H Atia Tariq alqahtani Department of Pharmacy Practice University of TabukTabuk 71491Saudi Arabia Department of Clinical Sciences Sulaiman Alrajhi UniversityQassim 52726Saudi Arabia Department of Family medicine International Medical CenterJeddah 23214Saudi Arabia Clinical and Administrative Pharmacy Sciences College of PharmacyHoward UniversityWashingtonDC 20059United States Department of Pharmacology King Saud Bin Abdulaziz University for Health SciencesKing Abdullah International Medical Research CenterRiyadh 11481Saudi Arabia

BACKGROUND Patients with diabetes mellitus(Dm)are predisposed to an increased risk of infection signifying the importance of vaccination to protect against its potentially severe *** Centers for Disease Control and Prevention/Advisory Committee on Immunization Practices(CDC/ACIP)issued immunization recommendations to protect this patient *** To assess the adherence of patients with Dm to the CDC/ACIP immunization recommendations in Saudi Arabia and to identify the factors associated with the vaccine adherence *** An observational retrospective study conducted in 2023 was used to collect data on the vaccination records from 13 diabetes care centers in Saudi Arabia with 1000 eligible patients in phase I with data collected through chart review and 709 patients in phase II through online *** Among participants,10.01%(n=71)had never received any vaccine,while 85.89%(n=609)received at least one dose of the coronavirus disease 2019(COVID-19)vaccine,and 34.83%(n=247)had received the annual influenza *** 2.96%(n=21),2.11%(n=15),and 1.12%(n=8)received herpes zoster,tetanus,diphtheria,and pertussis(Tdap),and human papillomavirus(HPV)vaccines,*** patients with Dm in Saudi Arabia,the rate of vaccination for annual influenza and COVID-19 vaccines was higher compared to other vaccinations such as herpes zoster,Tdap,pneumococcal,and *** such as vaccine recommendations provided by family physicians or specialists,site of care,income level,Dm-related hospitalization history,residency site,hemoglobin A1c(HbA1c)level,and health sector type can significantly influence the vaccination rate in patients with *** non-vaccinated patients with Dm,the most reported barriers were lack of knowledge and fear of side *** signifies the need for large-scale research in this area to identify additional factors that might facilitate adherence to CDC/ACIP vaccine recommendations in patients with *** In S

关键词： Diabetes mellitus Vaccine recommendation COVID-19 vaccine Influenza vaccine Pneumococcal vaccine Immunization Retrospective study

Antibacteria Activity of Peganum harmala and Haloxylon salicornicum Leaves Extracts

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Advances in microbiology 2024年第2期14卷 122-136页

作者： Naif m. Alhawiti Agnes K. Nthenge Waeel H. Alramadhan William Boadi Abdulrahman F. alqahtani Elber-Lewis myles CAHFS University of California Davis USA Department of Agricultural and Environmental Sciences College of Agriculture Tennessee State University Nashville USA Department of Biological Science Tennessee State University Nashville USA Department of Chemistry Tennessee State University Nashville USA Saudi Food and Drug Authority Riyadh Saudi Arabia

The use of antibiotics in humans and animals has been marked as a significant step in health due to their effectiveness in controlling and treating bacterial infections. The misuse and overuse of antibiotics have been identified as risk factors for bacterial resistance since microorganisms adapt and develop mechanisms to defend against antibiotics. According to the Centers for Disease Protection and Control (CDC), around 23,000 individuals die every year in the United States due to antibiotic resistance complications. As a result, a demand for alternative treatments has been a goal for scientists as the microbes adapt to selective pressure. The aim of this study is to test the antibacterial activity of leaf extracts of Peganum harmala and Haloxylon salicornicum on both Gram-positive and Gram-negative bacteria on various mediums. The results of the study showed that both P. harmala and H. salicornicum inhibited the bacterial growth in two different media. The results were also compared with different common antibiotics used in both human’s and animal’s fields and showed a promising outcome as alternative antibiotics.

关键词： Peganum harmala Haloxylon salicornicum Antibiotics Resistance medicinal Plants Gram-Positive Gram-Negative

Optimal entry point for antegrade and retrograde femoral intramedullary nails

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Chinese Journal of Traumatology 2023年第5期26卷 249-255页

作者： mohammad m.Alzahrani Yousef Aljamaan Jaffar Alsayigh Shahad Alghamdi Saad m.alqahtani Steven R.Papp Orthopedic Surgery Department College of MedicineImam Abdulrahman Bin Faisal UniversityDammamSaudi Arabia Division of Orthopaedic Surgery University of OttawaThe Ottawa HospitalOttawaOntarioCanada

Surgical management of femoral shaft fractures with intramedullary nails has become the standard ofcare,with multiple options for entry point described,including piriformis entry,trochanter entry andretrograde femoral *** present review describes the surgical anatomy of the proximal and distalfemur and its relation to different entry points for intramedullary femoral *** addition,we reviewedrelative indications for each technique,difficulties associated and possible complications.

关键词： Femurfracture Antegrade Retrograde Femoral nailing

Automated Speech Recognition System to Detect Babies’ Feelings through Feature Analysis

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Computers, materials & Continua 2022年第11期73卷 4349-4367页

作者： Sana Yasin Umar Draz Tariq Ali Kashaf Shahid Amna Abid Rukhsana Bibi muhammad Irfan mohammed A.Huneif Sultan A.Almedhesh Seham m.alqahtani alqahtani Abdulwahab mohammed Jamaan Alzahrani Dhafer Batti Alshehri Alshehri Ali Abdullah Saifur Rahman Faculty of Computing University of OkaraOkara57000Pakistan Department of Computer Science University of SahiwalSahiwal57000PunjabPakistan Computer Science Department COMSATS University IslamabadLahore Campus57000Pakistan Department of Computer Science CUISahiwal CampusSahiwal57000Pakistan Electrical Engineering Department College of EngineeringNajran University Saudi ArabiaNajran61441Saudi Arabia Pediatric Department Medical CollegeNajran University Saudi ArabiaNajran61441Saudi Arabia Consultant of ORL&HNs and Facial Plastic Surgery College of MedicineNajran University Saudi ArabiaNajran61441Saudi Arabia

Diagnosing a baby’s feelings poses a challenge for both doctors and parents because babies cannot explain their feelings through expression or *** the emotions of babies and their associated expressions during different sensations such as hunger,pain,etc.,is a complicated *** infancy,all communication and feelings are propagated through cryspeech,which is a natural *** clinical methods can be used to diagnose a baby’s diseases,but nonclinical methods of diagnosing a baby’s feelings are *** such,in this study,we aimed to identify babies’feelings and emotions through their cry using a nonclinical *** in the cry sound can be identified using our method and used to assess the baby’s *** considered the frequency of the cries from the energy of the *** feelings represented by the infant’s cry are judged to represent certain sensations expressed by the child using the optimal frequency of the recognition of a real-world audio *** used machine learning and artificial intelligence to distinguish cry tones in real time through feature *** experimental group consisted of 50%each male and female babies,and we determined the relevancy of the results against different *** application produced real-time results after recognizing a child’s cry *** novelty of our work is that we,for the first time,successfully derived the feelings of young children through the cry-speech of the child,showing promise for end-user applications.

关键词： Cry-to-speak machine learning artificial intelligence cry speech detection babies

Awareness and knowledge about glaucoma among patients visiting the screening clinic in Jeddah Eye Hospital,Saudi Arabia

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International Journal of Ophthalmology(English edition) 2021年第6期14卷 887-895页

作者： Saleh m.alqahtani marwan A Bakarman Ahmed Almanjoumi Sami H.Alzahrani ministry of Health Jeddah 23545Saudi Arabia Department of Family and Community medicine Faculty of Medicine in RabighKing Abdul Aziz UniversityJeddah 21589Saudi Arabia Ophthalmology Department Faculty of MedicineKing Abdulaziz UniversityJeddah 22234Saudi Arabia Family medicine Department Faculty of MedicineKing Abdulaziz UniversityJeddah 22431Saudi Arabia

AIm:To explore levels and determinants of awareness and knowledge about glaucoma among ***:This was a cross-sectional study that included adult patients from October to the end of December 2018.A semi-structured questionnaire was designed by the researchers to measure the levels of awareness and knowledge about 18 basic information about *** sheet was divided into 4 domains:types of glaucoma,risk factors,clinical features,and management.A knowledge score(KS,range=0-18)was calculated,with higher scores indicating higher ***:A total of 383 patients responded to the questionnaire,61.9%males,mean±SD age was 38.5±12.94 years old,and 61.6%had a university degree or *** them,6.3%and 23.2%reported personal and family history of glaucoma,*** most frequently reported source of information about glaucoma was another person with glaucoma(28.2%),followed by physicians(24.8%)and TV(19.6%).Knowledge by item ranged from 3.1%to 82.5%correctness rate,while KS showed mean=5.91 and median=5;and reliability testing of the knowledge scale showed Cronbach’s alpha=*** KS were found among respondents with higher educational level(P=0.036),diabetes history(P=0.025),and personal(Pmily(Pma among the attendees of a local eye care hospital,where several misconceptions about disease risk factors,clinical features,and management are identified.

关键词： awareness knowledge glaucoma Saudi Arabia

Discovery of human coronaviruses pan-papain-like protease inhibitors using computational approaches

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Journal of Pharmaceutical Analysis 2020年第6期10卷 546-559页

作者： mubarak A.Alamri muhammad Tahir ul Qamar muhammad Usman mirza Safar m.alqahtani matheus Froeyen Ling-Ling Chen Department of Pharmaceutical Chemistry College of PharmacyPrince Sattam Bin Abdulaziz UniversityAlkarjSaudi Arabia College of Life Science and Technology Guangxi UniversityNanningChina Department of Pharmaceutical and Pharmacological Sciences Rega Institute for Medical ResearchMedicinal ChemistryUniversity of LeuvenB-3000LeuvenBelgium Hubei Key Laboratory of Agricultural Bioinformatics College of InformaticsHuazhong Agricultural UniversityWuhan430070China

The papain-like protease(PLpro)is vital for the replication of coronaviruses(Co Vs),as well as for escaping innate-immune responses of the ***,it has emerged as an attractive antiviral *** this study,computational approaches were employed,mainly the structure-based virtual screening coupled with all-atom molecular dynamics(mD)simulations to computationally identify specific inhibitors of severe acute respiratory syndrome coronavirus 2(SARS-Co V-2)PLpro,which can be further developed as potential pan-PLprobased broad-spectrum antiviral *** sequence,structure,and functional conserveness of most deadly human Co Vs PLprowere explored,and it was revealed that functionally important catalytic triad residues are well conserved among SARS-Co V,SARS-Co V-2,and middle east respiratory syndrome coronavirus(mERS-Co V).The subsequent screening of a focused protease inhibitors database composed of^7,000 compounds resulted in the identification of three candidate compounds,ADm13083841,LmG15521745,and *** three compounds established conserved interactions which were further explored through mD simulations,free energy calculations,and residual energy contribution estimated by mm-PB(GB)SA *** these compounds showed stable conformation and interacted well with the active residues of SARS-Co V-2 PLpro,and showed consistent interaction profile with SARS-Co V PLproand mERS-Co V PLproas ***,the reported SARS-Co V-2 PLprospecific compounds could serve as seeds for developing potent pan-PLprobased broad-spectrum antiviral drugs against deadly human ***,the presented information related to binding site residual energy contribution could lead to further optimization of these compounds.

关键词： COVID-19 mERS-CoV molecular dynamic simulation Pan-inhibitors Papain-like protease SARS-CoV SARS-CoV-2 Virtual screening