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Readmission rate and early complications in patients undergoing total knee arthroplasty:A retrospective study

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World Journal of Orthopedics 2024年第8期15卷 713-721页

作者： Tushar Jethi Deepak Jain rajnish Garg Harpal Singh Selhi Department of Orthopedics Fortis Hospital LudhianaLudhiana 141123PunjabIndia Department of Orthopedics Dayanand Medical College&HospitalLudhiana 141001PunjabIndia Department of Orthopedic Surgery Dayanand Medical College&HospitalLudhiana 141001PunjabIndia

BACKGROUND Total knee arthroplasty(TKA)can improve pain,quality of life,and functional *** uncommon,postoperative complications are extremely consequential and thus must be carefully tracked and communicated to patients to assist their decision-making before *** of the risk factors for complications and readmissions after TKA,taking into account common causes,temporal trends,and risk variables that can be changed or left unmodified,will benefit this *** To assess readmission rates,early complications and their causes after TKA at 30 days and 90 days *** This was a prospective and retrospective study of 633 patients who underwent TKA at our hospital between January 1,2017,and February 28,*** the 633 patients,28 were not contactable,leaving 609 who met the inclusion *** inpatient and outpatient hospital records were retrieved,and observations were noted in the data collection *** Following TKA,the 30-day and 90-day readmission rates were determined to be 1.1%(n=7)and 1.8%(n=11),*** unplanned visit rate at 30 days following TKA was 2.6%(n=16)and at 90 days was 4.6%(n=28).At 90 days,the unplanned readmission rate was 1.4%(n=9).Reasons for readmissions included medical(27.2%,n=3)and surgical(72.7%,n=8).Unplanned readmissions and visits within 90 days of follow-up did not substantially differ by age group(P=0.922),body mass index(BMI)(P=0.633),unilateral vs bilateral TKA(P=0.696),or patient comorbidity status(30-day P=0.171 and 90-day P=0.813).Reoperation rates after TKA were 0.66%(n=4)at 30 days and 1.15%(n=8)at 90 *** average length of stay was 6.53 *** In this study,there was a low readmission rate following *** was no significant correlation between readmission rate and patient factors such as age,BMI,and co-morbidity status.

关键词： Total knee arthroplasty Length of stay Readmission Rates Causes Risk factors Prospective Retrospective Follow-up Reoperation

The rheological model of biodiesels at elevated pressures and temperatures

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Clean Energy 2022年第3期6卷 438-445页

作者： Piyush Kuchhal rajnish Garg Department of Physics School of EngineeringUPESIndia Department of Mechanical Engineering School of EngineeringUPESIndia

In the present study,an approximation is used to study viscosity as a function of pressure at different *** correlation so obtained is applied to study the viscosity of biodiesels extracted from soybean,Vistive soybean,canola,used canola,coconut and *** computed values of viscosity from the proposed model were found to be in good agreement with experimental data throughout the range of pressure and temperature *** maximum average absolute relative deviation(AARD%)and mean AARD%are found to be 0.52 and 0.20,respectively,over the entire range of pressure(0.1-140 MPa)and temperature(283.15-373.15 K)for all biodiesels except rapeseed biodiesel,for which the values are 1.1 and 0.62,***,this work includes the very first investigation conducted so far on the variation of the pressure-viscosity coefficient(PVC)with pressure at different temperatures for *** variation in PVC with the temperature is more sensitive at elevated pressures as compared to atmospheric pressure whereas the variation in PVC with pressure is more sensitive at elevated temperatures as compared to room temperature.

关键词： renewable fuel biodiesels viscosity pressure-viscosity coefficient pressure temperature

Influence of particle size and temperature on the dielectric properties of CoFe_2O_4 nanoparticles

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International Journal of Minerals,Metallurgy and Materials 2014年第4期21卷 408-414页

作者： Deepshikha Rathore rajnish Kurchania R.K.Pandey NIIT University Department of Physics Maulana Azad National Institute of Technology (MANIT)

The objective of this study was to establish the dielectric properties of CoFe2O4 nanoparticles with particle sizes that varied from 28.6 to 5.8 nm. CoFe2O4 nanoparticles were synthesized using a chemical coprecipitation method. The particle sizes were calculated accord-ing to the Scherrer formula using X-ray diffraction （XRD） peaks, and the particle size distribution curves were constructed by using field-emission scanning electron microscopy （FESEM） images. The dielectric permittivity and loss tangents of the samples were determined in the frequency range of 1 kHz to 1 MHz and in the temperature range of 300 to 10 K. Both the dielectric permittivity and the loss tangent were found to decrease with increasing frequency and decreasing temperature. For the smallest CoFe2O4 nanoparticle size, the dielectric per-mittivity and loss tangent exhibited their highest and lowest values, respectively. This behavior is very useful for materials used in devices that operate in the microwave or radio frequency ranges.

关键词： cobalt ferrite nanoparticles coprecipitation dielectric properties permittivity loss tangent particle size temperature

Recent trends in stem cell-based therapies and applications of artificial intelligence in regenerative medicine

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World Journal of Stem Cells 2021年第6期13卷 521-541页

作者： Sayali Mukherjee Garima Yadav rajnish Kumar Amity Institute of Biotechnology Amity University Uttar PradeshLucknow 226028Uttar PradeshIndia

Stem cells are undifferentiated cells that can self-renew and differentiate into diverse types of mature and functional cells while maintaining their original *** profound potential of stem cells has been thoroughly investigated for its significance in regenerative medicine and has laid the foundation for cellbased *** medicine is rapidly progressing in healthcare with the prospect of repair and restoration of specific organs or tissue injuries or chronic disease conditions where the body’s regenerative process is not sufficient to *** this review,the recent advances in stem cell-based therapies in regenerative medicine are discussed,emphasizing mesenchymal stem cell-based therapies as these cells have been extensively studied for clinical *** applications of artificial intelligence algorithms in stem cell-based therapies,their limitation,and future prospects are highlighted.

关键词： Artificial intelligence Machine learning Mesenchymal stem cells Regenerative medicine Stem cells Therapy

Molecular dynamics study on growth of carbon dioxide and methane hydrate from a seed crystal

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Chinese Journal of Chemical Engineering 2019年第9期27卷 2074-2080页

作者： Prajakta Nakate Bappa Ghosh Subhadip Das Sudip Roy rajnish Kumar Chemical Engineering and Process Development National Chemical LaboratoryPune 411008India Physical and Materials Chemistry Division National Chemical LaboratoryPune 411008India Department of Chemistry Chaudhary Ranbir Singh UniversityfindHaryana-126102 Department of Chemical Engineering Indian Institute of TechnologyMadrasChennai 600036Tamil NaduIndia

In the current work,molecular dynamics simulation is employed to understand the intrinsic growth of carbon dioxide and methane hydrate starting from a seed crystal of methane and carbon dioxide *** comparison was carried out because it has relevance to the recovery of methane gas from natural gas hydrate reservoirs by simultaneously sequestering a greenhouse gas like *** seed crystal of carbon dioxide and methane hydrate was allowed to grow from a super-saturated mixture of carbon dioxide or methane molecules in water *** different concentrations(1:6 and 1:8.5)of CO2/CH4 molecules per water molecule were chosen based on gas–water composition in hydrate *** molecular level growth as a function of time was investigated by all atomistic molecular dynamics simulation under suitable temperature and pressure range which was well above the hydrate stability zone to ensure significantly faster growth *** concentration of CO2 molecules in water played a significant role in growth kinetics,and it was observed that maximizing the CO2 concentration in the aqueous phase may not result in faster growth of CO2 *** the contrary,methane hydrate growth was independent of methane molecule concentration in the aqueous *** have validated our results by performing experimental work on carbon dioxide hydrate where it was seen that under conditions appropriate for liquid CO2,the growth for carbon dioxide hydrate was very slow in the beginning.

关键词： CH4 recovery Natural gas hydrate CO2 sequestration Kinetics F4 order parameter Cage dynamics Thermodynamics

Nanomaterials for sensing of formaldehyde in air: Principles, applications, and performance evaluation

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Nano Research 2019年第2期12卷 225-246页

作者： Deepak Kukkar Kowsalya Vellingiri rajnish Kaur Sanjeev Kumar Bhardwaj Akash Deep Ki-Hyun Kim Department of Nanotechnology Sri Guru Granth Sahib World University Fatehgarh Sahib Punjab 140406 India Department of Civil and Environmental Engineering Hanyang University Seoul 04763 Republic of Korea Environmental and Water Resources Engineering Division Department of Civil Engineering IIT Madras Chennai 600036 India Central Scientific Instruments Organization (CSIR-CSIO) Sector 30C Chandigarh 160030 India

Despite the improvement in sensing technologies, detection of small and highly reactive molecules like formaldehyde remains a highly challenging area of research. Applications of nanomaterials/nanostructures and their composites have increased as effective sensing platforms (e.g., reaction time, sensitivity, and selectivity) for the detection of aqueous or gaseous formaldehyde based on diverse sensing principles. In this review, the basic aspects of important nanomaterial-based sensing systems (e.g., electrochemical, electrical, biological, and mass variation sensors) were evaluated in relation to performance, cost, and practicality of sensing gas phase formaldehyde. Accordingly, existing knowledge gaps in such applications were assessed in various respects along with suitable recommendations for building a new roadmap for the expansion of chemical sensing technology of gas phase formaldehyde.

关键词： nanomaterials formaldehyde hazardous pollutant sensing

Investigation on the effect of oxalic acid, succinic acid and aspartic acid on the gas hydrate formation kinetics

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Chinese Journal of Chemical Engineering 2019年第9期27卷 2148-2156页

作者： Sheshan Bhimrao Meshram Omkar S.Kushwaha Palle Ravinder Reddy Gaurav Bhattacharjee rajnish Kumar Department of Chemical Engineering Indian Institute of Technology

Gas hydrate reserves are potential source of clean energy having low molecular weight hydrocarbons trapped in water *** this work,we report how organic compounds of different chain lengths and hydrophilicities when used in small concentration may modify hydrate growth and either act as hydrate inhibitors or *** promoters foster the hydrate growth kinetics and are used in novel applications such as methane storage as solidified natural gas,desalination of sea water and gas *** the other hand,gas hydrate inhibitors are used in oil and gas pipelines to alter the rate at which gas hydrate nucleates and *** such as methanol and ethanol which form strong hydrogen bond with water have been traditionally used as hydrate ***,due to relatively high volatility a significant portion of these inhibitors ends up in gas stream and brings further complexity to the safe transportation of natural *** this study,organic additives such as oxalic acid,succinic acid and L-aspartic acid(all three)having––COOH group(s)with aspartic acid having an additional––NH2 group,are investigated for gas hydrate promotion/inhibition *** compounds are polar in nature and thus have significant solubility in liquid water;the presence of weak acidic and water loving(carboxylic/amine groups)moieties makes these organic acids an excellent candidate for further *** study would pave ways to identify a novel(read better)promoter/inhibitor for gas hydrate *** thermodynamic conditions were generated in a stirred tank reactor coupled with cooling system;comparison of gas hydrate formation kinetics with and without additives were carried out to identify the effect of these acids on the formation and growth of *** possible mechanisms by which these additives inhibit or promote the hydrate growth are also discussed.

关键词： Flow assurance Gas hydrates kinetics Hydrate promoters Hydrate inhibitors Inhibition mechanism Gas uptake measurement Induction time

Comparison of gliclazide vs linagliptin on hypoglycemia and cardiovascular events in type 2 diabetes mellitus: A systematic review

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World Journal of Diabetes 2022年第12期13卷 1168-1183页

作者： Viswanathan Mohan Subhash Wangnoo Sambit Das rajnish Dhediya Kumar Gaurav Department of Diabetes Madras Diabetes Research Foundation&Dr Mohan’s Diabetes Specialties CentreChennai 600086Tamil NaduIndia Department of Diabetes Apollo Hospital Education and Research FoundationNew Delhi 110001India Department of Endocrinology Endeavour ClinicsBhubaneswar 750017India Medical Affairs Dr.Reddy’s Laboratories LtdHyderabad 500016India

BACKGROUND Cardiovascular outcome trials have demonstrated cardiovascular safety of glimepiride(a sulfonylureas) against dipeptidyl peptidase-4 inhibitor ***(another newer sulfonylureas) has shown similar glycemic efficacy and 50% decreased risk of hypoglycemia compared to *** Considering the absence of cardiovascular outcome trials for gliclazide, we decided to conduct a systematic review of the literature to assess the cardiovascular(CV) safety by assessing the risk for major adverse CV events and hypoglycemia risk of gliclazide vs linagliptin in patients with type 2 diabetes(T2D).METHODS This systematic review followed the current Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines to analyze all the clinical studies published from 2008 that compared the two drugs in patients with T2D with no risk of CV disease(CVD). We included only evidence designated high quality by the Oxford Center for Evidence-based Medicine-Levels of *** Eight clinical studies were included in the narrative descriptive analysis(gliclazide: 5 and linagliptin: 3). The CV safety of gliclazide in the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation trial and of linagliptin in the Cardiovascular and Renal Microvascular Outcome Study With Linagliptin(CARMELINA) and CARdiovascular Outcome study of LINAgliptin vs glimepiride in patients with T2D(CAROLINA)trials were excluded from the comparative analysis as these trials demonstrated CV and hypoglycemia benefits in patients at high risk of CVD. However, since these are landmark trials,they were discussed in brief to show the CV benefits and low hypoglycemia risk of gliclazide and linagliptin. We did not find any study comparing gliclazide with linagliptin. Hence, direct comparison of their major adverse CV events and hypoglycemia risk could not be carried ***, the literature meeting the inclusion criteria showed that b

关键词： Linagliptin Gliclazide Hypoglycemia Major cardiovascular adverse events Type 2 diabetes

Oral cysticercosis-a rare presentation

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Asian Pacific Journal of Tropical Medicine 2011年第7期4卷 587-588页

作者： Singh Sunita Chhabra Sonia Aggarwal Garima Kalra rajnish Duhan Amrita Sen Rajeev Department of Pathology Pt.B.D.Sharma PGIMSRohtakIndia

Cysticercosis is a condition that occurs when man is infected with larvae of Taenia *** cysticercosis is a rare event,and it represenls difficulty in clinical diagnosis.A case of oral cysticercosis in 11 year old girl is presented which complained of painless swelling for 6 months. A FNAC was performed which revealed bluish pink fibrillary material and interspersed nuclei and fragments of wall of *** was treated with antihelminthic.

关键词： Oral cysticercosis Taenia solium Cysticercus celiuiosae