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Frontiers of Mechanical Engineering 2016年第4期11卷 374-387页

作者： Jagdeep SINGH rajiv Kumar sharma Department of Mechanical Engineering National Institute of Technol-ogy Hamirpur Himachal Pradesh-177005 India

Electrical discharge machining (EDM) is a well-known nontraditional manufacturing process to machine the difficult-to-machine (DTM) materials which have unique hardness properties. Researchers have successfully performed hybridization to improve this process by incorporating powders into the EDM process known as powder-mixed EDM process. This process drastically improves process efficiency by increasing material removal rate, micro-hardness, as well as reducing the tool wear rate and surface roughness. EDM also has some input parameters, including pulse-on time, dielectric levels and its type, current setting, flushing pressure, and so on, which have a significant effect on EDM performance. However, despite their positive influence, investigating the effects of these parameters on environmental conditions is necessary. Most studies demonstrate the use of kerosene oil as dielectric fluid. Nevertheless, in this work, the authors highlight the findings with respect to three different dielectric fluids, including kerosene oil, EDM oil, and distilled water using one-variable-at-a-time approach for machining as well as environmental aspects. The hazard and operability analysis is employed to identify the inherent safety factors associated with powder-mixed EDM of WC-Co.

关键词： WC hazard and operability analysis (HAZOP) discharging aerosol concentration dielectrics powders

Analytical modeling of drain current and RF performance for double-gate fully depleted nanoscale SOI MOSFETs

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Journal of Semiconductors 2012年第2期33卷 28-35页

作者： rajiv sharma Sujata Pandey Shail Bala Jain Department of Electronics and Communication Engineering Guru Gobind Singh Indraprastha UniversityDelhiIndia Department of Electronics and Communication Engineering Amity UniversitySector-125 NoidaIndia

A new 2D analytical drain current model is presented for symmetric double-gate fully depleted nanoscale SOI *** of device parameters like transconductance for double-gate fully depleted nanoscale SOI MOSFETs is also carried *** this work is concluded by modeling the cut-off frequency, which is one of the main figures of merit for analog/RF performance for double-gate fully depleted nanoscale SOI *** results of the modeling are compared with those obtained by a 2D ATLAS device simulator to verify the accuracy of the proposed model.

关键词： double-gate fully depleted silicon-on-insulator Poisson's equation radio frequency ATLAS

Numerical Analysis of Phase Change and Container Materials for Thermal Energy Storage in the Storage Tank of Solar Water Heating System

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Journal of Thermal Science 2024年第2期33卷 408-421页

作者： SINGH Shailendra ANAND Abhishek SHUKLA Amritanshu sharma Atul Non-Conventional Energy Laboratory Rajiv Gandhi Institute of Petroleum TechnologyJais Amethi229304India

This study evaluates the effectiveness of phase change materials(PCMs) inside a storage tank of warm water for solar water heating(SWH) system through the theoretical simulation based on the experimental model of *** et *** model is explained by five fundamental equations for the calculation of various parameters like the effectiveness of PCMs,the mass of hot water,total heat content,and duration of *** study simulated eleven PCMs to analyze their effectiveness like Sodium hydrogen phosphate dodecahydrate(SHPD),OM 37,N-Eicosane(NE),Lauric acid(LA),Paraffin wax(PW),OM 48,Paraffin wax C_(20-33)(PW-C20-33),Sodium acetate trihydrate(SAT),Palmitic acid(PA),Myristic acid(MA),and Stearic acid(SA).Among all PCMs,the SHPD has found the highest value of effectiveness factor of ***,it is the most recommended PCM for the storage tank of the SWH *** study also includes the melt fraction analysis of all enumerated PCMs corresponding to container materials of stainless steel,glass,aluminum mixed,tin,aluminum,and *** melt fraction analysis is performed by making a coding program in the FORTRAN programming *** the analysis,copper container material is found to have high melting rate for all PCMs so it is superior to other container materials.

关键词： theoretical model solar water heating system phase change material effectiveness factor melt fraction

Proactive Connection Recovery Strategy with Recovery Time Constraint for Survivable Elastic Optical Networks

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China Communications 2021年第9期18卷 236-248页

作者： Dinesh Kumar rajiv Kumar Neeru sharma Department of Electronics&Communication Engineering Jaypee University of Information Technology WaknaghatSolan(HP)India

This paper presents a halfway signaling exchange shared path protection(HSE-SPP)on the backup route for a fast connection recovery *** the proposed HSE-SPP,a pre-assigned intermediate node on the backup route is chosen for signaling *** connection fails,source and destination nodes simultaneously generate backup connection setup messages to the pre-assigned intermediate node on the reserved backup *** the intermediate node,signaling process occurs,and acknowledgment is generated for data transmission to the respective end ***,connection recovery time by applying HSE-SPP becomes very *** are performed for network parameters and results are verified with existing *** average recovery time(RT),bandwidth blocking probability(BBP),bandwidth provisioning ratio(BPR),and resource overbuild(RO)ratio of HSE-SPP for ARPANET is 13.54 ms,0.18,3.02,0.55,and for dedicated path protection(DPP)are 13.20 ms,0.56,6.30,3.75 and for shared path protection(SPP)22.19 ms,0.22,3.23,0.70 ***,average RT,BBP,BPR and RO of HSE-SPP for COST239 are8.33 ms,0.04,1.64,0.26,and for DPP 4.23,0.47,3.50,2.04,and for SPP 11.81,0.08,1.66,0.27 ***,results of the proposed strategy are better in terms of RT,BBP,BPR,and RO ratio.

关键词： routing and spectrum assignment halfway signaling exchange-shared path protection(HSE-SPP) dedicated path protection bandwidth blocking probability(BBP)

Impact of open dumping of municipal solid waste on soil properties in mountainous region

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Journal of Rock Mechanics and Geotechnical Engineering 2018年第4期10卷 725-739页

作者： Anchal sharma Ashok Kumar Gupta rajiv Ganguly Department of Civil Engineering Jaypee University of Information Technology

This paper presents the effect of open dumping of municipal solid waste(MSW) on soil characteristics in the mountainous region of Himachal Pradesh, India. The solid waste of dumpsite contains various complex characteristics with organic fractions of the highest proportions. As leachate percolates into the soil, it migrates contaminants into the soil and affects soil stability and strength. The study includes the geotechnical investigation of dump soil characteristics and its comparison with the natural soil samples taken from outside the proximity of dumpsites. The geochemical analysis of dumpsite soil samples was also carried out by scanning electron microscopy(SEM) and energy dispersive X-ray spectroscopy(EDS).Visual inspection revealed that the MSW consists of high fraction of organics, followed by paper. The soil samples were collected from five trial pits in the dumpsites at depths of 0.5 m, 1 m and 1.5 m. Then the collected soil samples were subjected to specific gravity test, grain size analysis, Atterberg’s limit test,compaction test, direct shear test, California bearing ratio(CBR) test and permeability analysis. The study indicated that the dumpsite soils from four study regions show decreasing trends in the values of maximum dry density(MDD), specific gravity, cohesion and CBR, and increasing permeability as compared to the natural soil. The results show that the geotechnical properties of the soils at all four study locations have been severely hampered due to contamination induced by open dumping of waste.

关键词： Municipal solid waste (MSW) Physical characterization Soil pollution Open dumping Scanning electron microscopy (SEM) Energy disperse X-ray spectroscopy (EDS)

Intermediate Energy Coulomb Excitation of Neutron-Rich Nuclei

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Chinese Physics Letters 2010年第3期27卷 104-107页

作者： rajiv Kumar Rajesh Kharab H. C. sharma Department of Applied Sciences Haryana College of Technology and Management Kaithal-136027 India Department of Physics Kurukshetra University Kurukshetra-136119 India

We reinvestigate the collective effects of the retardation as well as the bending on the Coulomb excitation cross sections and also on the B（E2） strengths of some neutron-rich isotopes using the intermediate energy Coulomb excitation theory. It is found that the B（E2） strengths extracted from the experimental Coulomb excitation cross section data get suppressed approximately by 6%. Furthermore, the obtained B（E2） strengths in the energy range 30-100 MeV/A are found to be in better agreement with the corresponding values known from other sources, than those obtained by using the recoil-corrected relativistic Coulomb excitation theory.

关键词： Nuclear physics

Comparative analysis of real-world data of frequent treatment sequences in metastatic prostate cancer

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Current Urology 2024年第2期18卷 104-109页

作者： Jiten Jaipuria Ishleen Kaur Mohammad Najmud Doja Tanvir Ahmad Amitabh Singh Sudhir Kumar Rawal Vineet Talwar Girish sharma Uro-oncology division Rajiv Gandhi Cancer Institute and Research CentreNew DelhiIndia Amity Centre for Cancer Epidemiology and Cancer Research Amity Institute of BiotechnologyAmity UniversityNoidaIndia School of Engineering and Technology Vivekananda Institute of Professional Studies–Technical CampusNew DelhiIndia Department of Computer Engineering Jamia Millia IslamiaNew DelhiIndia Indian Institute of Information Technology SonepatIndia Department of MedicalOncology Rajiv Gandhi Cancer Institute and Research CentreNew DelhiIndia

Background:The incidence of prostate cancer is increasing worldwide.A significant proportion of patients developmetastatic disease and are initially prescribed androgen deprivation therapy(ADT).However,subsequent sequences of treatments in real-world settings that may improve overall survival remain an area of active *** and methods:Data were collected from 384 patients presenting with de novo metastatic prostate cancer from 2011 to 2015 at a tertiary cancer *** were categorized into surviving(n=232)and deceased(n=152)groups at the end of 3 *** sequence pattern mining techniques(Generalized Sequential Pattern Mining and Sequential Pattern Discovery using Equivalence Classes)were applied to determine the exact order of the most frequent sets of treatments in each ***:Degarelix,as the initial form of ADT,was uniquely in the surviving *** sequence of ADT followed by abiraterone and docetaxel was uniquely associated with a higher 3-year overall *** followed by fosfestrol was found to have a unique niche among surviving patients with a long duration of response to the initial *** who received chemotherapy followed by radiotherapy and those who received radiotherapy followed by chemotherapy were found more frequently in the deceased ***:We identified unique treatment sequences among surviving and deceased patients at the end of 3 *** should be the preferred formof *** who received ADT followed by abiraterone and chemotherapy showed better *** requiring palliative radiation and chemotherapy in any sequence were significantlymore frequent in the deceased group,identifying the need to offer such patients the most efficacious agents and to target them in clinical trial design.

关键词： Hormone therapy Metastatic prostate cancer Sequence mining Survival

Comparison of encirclage and cryotherapy with argon laser in the management of traumatic cyclodialysis cleft

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International Journal of Ophthalmology(English edition) 2019年第1期12卷 165-168页

作者： Gitanjli Sood Vinata Rajendran Ronnie George Tarun sharma rajiv Raman Shri Bhagawan Mahavir Vitreo Retinal Services Sankara Nethralaya Department of Glaucoma Medical Research FoundationSankara NethralayaChennai

The study compared anatomical and functional outcome of a novel technique of encirclage and cryotherapy with the conventional argon laser in the management of traumatic cyclodialysis cleft in 19 patients(10: encirclage and 9: argon laser). The postoperative anatomical success was taken as rise in intraocular pressure(IOP) more than 6 mm Hg or the closure of cleft on gonioscopy or ultrasound biomicroscopy(UBM). Visual outcome was measured as change in logMAR visual acuity. Traumatic cataract and hypotony were present in majority. IOP>6 mm Hg was noted in 90% of encirclage group and in 77.70% of argon laser group. Two cases had non-closure of cleft. Encirclage is comparable to argon laser in terms of anatomical and functional success with possible advantage of single procedure and use in cases with failed laser.

关键词： traumatic cyclodialysis encirclage cryotherapy laser hypotony

Evaluating newer generation intraocular lens calculation formulas in manual versus femtosecond laser-assisted cataract surgery

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International Journal of Ophthalmology(English edition) 2021年第8期14卷 1174-1178页

作者： Harrish Nithianandan Soumya sharma Eric S.Tam Hannah Chiu rajiv Maini Sohel Somani Department of Ophthalmology&Visual Sciences McGill UniversityMontreal H4A 3S5Canada Ryerson University TorontoOntario M5B 2K3Canada Department of Ophthalmology University of TorontoToronto M5T 3A9Canada Uptown Eye Specialists VaughanOntario L4K 2Z5Canada William Osler Health System BramptonOntario L6R 3J7Canada

AIM:To determine the refractive accuracy of the Haigis,Barrett Universal II(Barrett),and Hill-radial basis function 2.0(Hill-RBF)intraocular lens(IOL)power calculations formulas in eyes undergoing manual cataract surgery(MCS)and refractive femtosecond laser-assisted cataract surgery(Re LACS).METHODS:This was a REB-approved,retrospective interventional comparative case series of 158 eyes of 158 patients who had preoperative biometry completed using the IOL Master 700 and underwent implantation of a Tecnis IOL following uncomplicated cataract surgery using either MCS or *** spherical equivalence(SE)was predicted using the Haigis,Barrett,and Hill-RBF *** older generation formula(Hoffer Q)was included in the *** refractive error(ME)was calculated one month *** lens factors of all formulas were retrospectively optimized to set the ME to 0 for each formula across all *** median absolute errors(MedAE)and the proportion of eyes achieving an absolute error(AE)within 0.5 diopters(D)were compared between the two formulas among MCS and ReLACS eyes,***:Of the 158 eyes studied,64 eyes underwent MCS and 94 eyes underwent *** MCS eyes,the MedAE did not differ between the formulas(P=0.59),however among ReLACS eyes,Barrett and Hill-RBF were more accurate(P=0.001).Barrett and Hill-RBF were both more likely to yield AE<0.5 D among both groups(P<0.001).CONCLUSION:The Barrett and Hill-RBF formula lead to greater refractive accuracy and likelihood of refractive success when compare to Haigis in eyes undergoing Re LACS.

关键词： phacoemulsification cataract femtosecond laser intraocular lens

Effect of hydrogen bond formation/replacement on solubility characteristics, gastric permeation and pharmacokinetics of curcumin by application of powder solution technology

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Acta Pharmaceutica Sinica B 2016年第6期6卷 600-613页

作者： Vijay sharma Kamla Pathak Department of Pharmaceutics Rajiv Academy for Pharmacy

The present research aimed to improve the dissolution rate and bioavailability of curcumin using the potential of liquisolid technology. Twelve drug-loaded liquisolid systems (LS-1 to LS-12) were prepared using different vehicles (PEG 200, PEG 400 and Tween 80) and curcumin concentrations in vehicle (40%, 50%, 60% and 70%, w/w). The carrier [microcrystalline cellulose (MCC) PH102] to coat (Aerosil®) ratio was 20 in all formulations. The systems were screened for pre-compression properties before being compressed to liquisolid tablets (LT-1 to LT-12). Post compression tests and in vitro dissolution of LTs were conducted and the results compared with those obtained for a directly compressed tablet (DCT) made of curcumin, MCC PH102 and Aerosil®. LTs exhibited higher cumulative drug release (CDR) than the DCT and the optimum formulation, LT-9 (made using Tween 80), was studied by powder XRD, DSC, SEM and FTIR. Ex-vivo permeation of curcumin from LT-9 through goat gastrointestinal mucosa was significantly (P50) of LT-9 towards NCL 87 cancer cells was 40.2 µmol/L substantiating its anticancer efficacy. Accelerated stability studies revealed insignificant effects of temperature and humidity on LT-9. In summary, solubility enhancement of curcumin in LTs produced significant improvements in its permeation and bioavailability.

关键词： Liquisolid tablet Powder solution technology Curcumin Hydrogen bond formation Cytotoxicity Gastric permeation Bioavailability Pharmacokinetics