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Open Journal of Urology 2022年第12期12卷 589-595页

作者： rajiv kumar sethia Aakib Hamid Charag Sidhu Sudeep Singh Nilesh Nirmal Agarwal Pankaj Ingole Department of Urology and Kidney Transplant Asian Institute of Medical Sciences Faridabad Haryana India Department of Cardiac Surgeon Metro Hospital Faridabad Haryana India Department of Cardiac Anasthesia Metro Hospital Faridabad Haryana India

A renal mass with level Level IV IVC thrombus is usually managed with radical nephrectomy and IVC thrombectomy. This procedure requires the assistance of a cardiac surgeon and is usually done under complete cardiopulmonary bypass. However, the use of cardiopulmonary bypass is associated with reduced cardiac venous return and can consequently decrease cardiac output, adversely affecting haemo-dynamic stability and systemic arterial perfusion. This can lead to relative ischemia of the abdominal viscera, lower limbs and kidneys. We report a case where radical nephrectomy with IVC thrombectomy was done under venovenous bypass, thus avoiding the complications associated with the cardiopulmonary bypass.

关键词： Nephrectomy IVC Thrombus Cardiopulmonary Bypass Venovenous Bypass

Resistance and resilience of soil biological indicators:A case study with multi-walled carbon nanotube

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Pedosphere 2024年第3期34卷 664-675页

作者： Shagufta YASMEEN Nintu MANDAL Anupam DAS Pritam GANGULY Sanjay kumar rajiv RAKSHIT Department of Soil Science and Agricultural Chemistry Bihar Agricultural UniversitySabourBhagalpur 813210(India) Department of Agronomy Bihar Agricultural UniversitySabourBhagalpur 813210(India)

Soil ecosystem is experiencing stresses due to climate change,and soil inhabitants try to demonstrate their inherent resistance and resilience against those *** of nanomaterials as agricultural inputs could bring shifts in resistance and resilience patterns of soil microbes and associated enzymes,especially under short-term heat *** this background,the impacts of multi-walled carbon nanotube(MWCNT)on the resistance and resilience of soil biological indicators were *** incubation experiment was conducted with varied MWCNT concentrations(0,50,100,250,and 500 mg kg-1soil)for 90 d after 24-h heat stress at 48±2?C to assess the impacts of MWCNT on soil enzyme activities and microbial populations vis-à-vis their resistance and resilience indices under short-term exposure to heat *** activities were reduced after exposure to heat *** indices of enzyme activities were enhanced by MWCNT application on day 1 after heat stress,whereas there was no recovery of enzyme activities after 90-d *** soil enzyme activities,resistance index values of soil microbial populations followed the similar trend and were improved by MWCNT ***-walled carbon nanotube has the potential to improve resistance indices of soil enzyme activities and microbial populations under heat stress,although they could not recover to their original state during periodical incubation after heat *** study helps to understand the relative changes of biological indicators under MWCNT and their ability to withstand heat stress.

关键词： enzyme activity heat stress microbial population nanomaterial recovery

Design of a Lightweight Compressed Video Stream-Based Patient Activity Monitoring System

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Computers, Materials & Continua 2024年第1期78卷 1253-1274页

作者： Sangeeta Yadav Preeti Gulia Nasib Singh Gill Piyush kumar Shukla Arfat Ahmad Khan Sultan Alharby Ahmed Alhussen Mohd Anul Haq Department of Computer Science&Applications Maharshi Dayanand UniversityRohtak124001India University Institute of Technology Rajiv Gandhi Proudyogiki VishwavidyalayaBhopal462033India Department of Computer Science College of ComputingKhon Kaen UniversityKhon Kaen40002Thailand Department of Computer Science College of Computer and Information SciencesMajmaah UniversityAl Majmaah11952Kingdom of Saudi Arabia Department of Computer Engineering College of Computer and Information SciencesMajmaah UniversityAl Majmaah11952Kingdom of Saudi Arabia

Inpatient falls from beds in hospitals are a common *** falls may result in severe *** problem can be addressed by continuous monitoring of patients using *** advancements in deep learning-based video analytics have made this task of fall detection more effective and *** with fall detection,monitoring of different activities of the patients is also of significant concern to assess the improvement in their *** computation-intensive models are required to monitor every action of the patient *** requirement limits the applicability of such ***,to keep the model lightweight,the already designed fall detection networks can be extended to monitor the general activities of the patients along with the fall *** by the same notion,we propose a novel,lightweight,and efficient patient activity monitoring system that broadly classifies the patients’activities into fall,activity,and rest classes based on their *** whole network comprises three sub-networks,namely a Convolutional Neural Networks(CNN)based video compression network,a Lightweight Pose Network(LPN)and a Residual Network(ResNet)Mixer block-based activity recognition *** compression network compresses the video streams using deep learning networks for efficient storage and retrieval;after that,LPN estimates human ***,the activity recognition network classifies the patients’activities based on their *** proposed system shows an overall accuracy of approx.99.7% over a standard dataset with 99.63% fall detection accuracy and efficiently monitors different events,which may help monitor the falls and improve the inpatients’health.

关键词： Fall detection activity recognition human pose estimation accuracy

Robust Optimization Method of Cylindrical Roller Bearing by Maximizing Dynamic Capacity Using Evolutionary Algorithms

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Journal of Harbin Institute of Technology(New Series) 2022年第5期29卷 20-40页

作者： kumar Gaurav rajiv Tiwari Twinkle Mandawat Department of Mechanical Engineering Indian Institute of Technology GuwahatiGuwahati 781039India

Optimization of cylindrical roller bearings(CRBs)has been performed using a robust *** ensures that the changes in the objective function,even in the case of variations in design variables during manufacturing,have a minimum possible value and do not exceed the upper limit of a desired range of percentage ***,it checks the feasibility of design outcome in presence of manufacturing tolerances in design *** any rolling element bearing,a long life indicates a satisfactory *** the present study,the dynamic load carrying capacity C,which relates to fatigue life,has been optimized using the robust *** roller bearings,boundary dimensions(i.e.,bearing outer diameter,bore diameter and width)are ***,the performance is mainly affected by the internal dimensions and not the bearing boundary dimensions mentioned *** spite of this,besides internal dimensions and their tolerances,the tolerances in boundary dimensions have also been taken into consideration for the robust *** problem has been solved with the elitist non-dominating sorting genetic algorithm(NSGA-II).Finally,for the visualization and to ensure manufacturability of CRB using obtained values,radial dimensions drawing of one of the optimized CRB has been *** check the robustness of obtained design after optimization,a sensitivity analysis has also been carried out to find out how much the variation in the objective function will be in case of variation in optimized value of design *** bearings have been found to have improved life as compared with standard ones.

关键词： cylindrical roller bearing optimization robust design elitist non-dominating sorting genetic algorithm(NSGA-II) fatigue life dynamic load carrying capacity

Influence of tool rotational speed on mechanical and corrosion behaviour of friction stir processed AZ31/Al_(2)O_(3)nanocomposite

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镁合金学报(英文) 2023年第7期11卷 2585-2599页

作者： Ashish kumar V.P.Singh Akhileshwar Nirala R.C.Singh rajiv Chaudhary Abdel-Hamid I.Mourad B.K.Sahoo Deepak kumar Department of Mechanical Engineering Delhi Technological UniversityDelhi 110042India Department of Mechanical Engineering Galgotias College of Engineering and Technology Greater Noida 201310India Department of Mechanical Engineering National Institute of Technology MizoramAizawl 796012India Department of Mechanical Engineering IES College of Technology Bhopal462044India Mechanical and Aerospace Engineering Department College of EngineeringUnited Arab Emirates UniversityAl-Ain 15551United Arab Emirates Materials Engineering Division CSIR-National Metallurgical Laboratory(NML)Jamshedpur831007India Department of Mechanical Engineering Carnegie Mellon UniversityPittsburghPA 15213USA

Nano-sized reinforcements improved the mechanical characteristics efficiently by promoting more implicit particle hardening mechanisms compared to micron-sized ***-sized particles lessen the critical particle solidification velocity for swamp and thus offers better *** the present investigation,the friction stir processing(FSP)is utilized to produce AZ31/Al_(2)O_(3)nanocomposites at various tool rotation speeds(i.e.,900,1200,and 1500 rpm)with an optimized 1.5%volume alumina(Al_(2)O_(3))reinforcement *** mechanical and corrosion behavior of AZ31/Al_(2)O_(3)-developed nanocomposites was investigated and compared with that of the AZ31 base *** AZ31 alloy experienced a comprehensive dynamic recrystallization during FSP,causing substantial grain ***-size strengthening is the primary factor contributed to the enhancement in the strength of the fabricated *** strength and yield strength values were lower than those for the base metal matrix,although an upward trend in both values has been observed with an increase in tool rotation *** 19.72%increase in hardness along with superior corrosion resistance was achieved compared to the base alloy at a tool rotational speed of 1500 *** corrosion currents(Jcorr)of all samples dropped with increase in the rotational speed,in contrast to the corrosion potentials(Ecorr),which *** values of Jcorr of AZ31/Al_(2)O_(3)were 42.3%,56.8%,and 65.5%lower than those of AZ31 alloy at the chosen rotating speeds of 900,1200,and 1500 rpm,*** corrosion behavior of friction stir processed nanocomposites have been addressed in this manuscript which has not been given sufficient attention in the existing ***,this work offers an effective choice for the quality assurance of the FSP process of AZ31/Al_(2)O_(3)*** obtained results are relevant to the development of lightweight automobile and aerospace structures and components

关键词： Friction stir processing AZ31 alloy Al_(2)O_(3) Nanocomposite Mechanical properties Corrosion resistance

Proactive Connection Recovery Strategy with Recovery Time Constraint for Survivable Elastic Optical Networks

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China Communications 2021年第9期18卷 236-248页

作者： Dinesh kumar rajiv kumar Neeru Sharma Department of Electronics&Communication Engineering Jaypee University of Information Technology WaknaghatSolan(HP)India

This paper presents a halfway signaling exchange shared path protection(HSE-SPP)on the backup route for a fast connection recovery *** the proposed HSE-SPP,a pre-assigned intermediate node on the backup route is chosen for signaling *** connection fails,source and destination nodes simultaneously generate backup connection setup messages to the pre-assigned intermediate node on the reserved backup *** the intermediate node,signaling process occurs,and acknowledgment is generated for data transmission to the respective end ***,connection recovery time by applying HSE-SPP becomes very *** are performed for network parameters and results are verified with existing *** average recovery time(RT),bandwidth blocking probability(BBP),bandwidth provisioning ratio(BPR),and resource overbuild(RO)ratio of HSE-SPP for ARPANET is 13.54 ms,0.18,3.02,0.55,and for dedicated path protection(DPP)are 13.20 ms,0.56,6.30,3.75 and for shared path protection(SPP)22.19 ms,0.22,3.23,0.70 ***,average RT,BBP,BPR and RO of HSE-SPP for COST239 are8.33 ms,0.04,1.64,0.26,and for DPP 4.23,0.47,3.50,2.04,and for SPP 11.81,0.08,1.66,0.27 ***,results of the proposed strategy are better in terms of RT,BBP,BPR,and RO ratio.

关键词： routing and spectrum assignment halfway signaling exchange-shared path protection(HSE-SPP) dedicated path protection bandwidth blocking probability(BBP)

Energy and Bandwidth Based Link Stability Routing Algorithm for IoT

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Computers, Materials & Continua 2022年第2期70卷 3875-3890页

作者： D.Kothandaraman A.Balasundaram R.Dhanalakshmi Arun kumar Sivaraman S.Ashokkumar rajiv Vincent M.Rajesh School of Computer Science and Artificial Intelligence SR UniversityWarangalTSIndia School of Computer Science and Engineering Center for Cyber Physical SystemsVellore Institute of Technology(VIT)ChennaiIndia Department of Computer Science and Engineering KCG College of TechnologyChennaiIndia School of Computer Science and Engineering Vellore Institute of Technology(VIT)ChennaiIndia Department of Computer Science and Engineering Saveetha School of EngineeringSIMATSChennaiIndia

Internet of Things(IoT)is becoming popular nowadays for collecting and sharing the data from the nodes and among the nodes using internet ***,some of the nodes in IoT are mobile and dynamic in *** maintaining the link among the nodes,efficient bandwidth of the links among the mobile nodes with increased life time is a big challenge in IoT as it integrates mobile nodes with static nodes for data *** such networks,many routing-problems arise due to difficulties in energy and bandwidth based quality of *** to the mobility and finite nature of the nodes,transmission links between intermediary nodes may fail frequently,thus affecting the routing-performance of the network and the accessibility of the *** existing protocols do not focus on the transmission links and energy,bandwidth and link stability of the nodes,but node links are significant factors for enhancing the quality of the *** stability helps us to define whether the node is within or out of a coverage *** paper proposed an Optimal Energy and bandwidth based Link Stability Routing(OEBLS)algorithm,to improve the link stable route with minimized error rate and *** this paper,the optimal route from the source to the sink is determined based on the energy and bandwidth,link stability *** the existing routes,the sink node will choose the optimal route which is having less link stability *** stable link is determined by evaluating link stability value using distance and ***-energy of the node is estimated using the current energy and the consumed *** energy is estimated using transmitted power and the received *** bandwidth in the link is estimated using the idle time and channel capacity with the consideration of probability of collision.

关键词： Link stability internet of things optimal energy optimal bandwidth residual energy

Synthetic and biological studies on a cyclopolypeptide of plant origin

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2008年第5期9卷 391-400页

作者： rajiv DAHIYA Akhilesh kumar Department of Pharmaceutical Chemistry Rajiv Academy for Pharmacy

Objective:A natural cyclic peptide previously isolated from Citrus medica was synthesized by coupling of tetrapep-tide units Boc-Leu-Pro-Trp-Leu-OMe and Boc-Ile-Ala-Ala-Gly-OMe after proper deprotection at carboxyl and amino terminals followed by cyclization of linear octapeptide segment. Methods:Solution phase technique was adopted for the synthesis of cyclooctapeptide-sarcodactylamide. Required tetrapeptide units were prepared by coupling of Boc-protected dipeptides viz. Boc-Leu-Pro-OH and Boc-Ile-Ala-OH with respective dipeptide methyl esters Trp-Leu-OMe and Ala-Gly-OMe. Cyclization of linear octapeptide unit was done by p-nitrophenyl ester method. The structure of synthesized cyclopolypeptide was elucidated by FTIR,1H NMR,13C NMR,FABMS spectral data and elemental analysis. The newly synthesized peptide was evaluated for dif-ferent pharmacological activities including antimicrobial,anthelmintic and cytotoxic activities. Results:Synthesis of sarcodac-tylamide was accomplished with >78% yield utilizing dicyclohexylcarbodiimide(DCC) as coupling agent. Newly synthesized peptide possessed potent cytotoxic activity against Dalton's lymphoma ascites(DLA) and Ehrlich's ascites carcinoma(EAC) cell lines,in addition to moderate anthelmintic activity against earthworms Megascoplex konkanensis,Pontoscotex corethruses and Eudrilus sp. Moreover,cyclopolypeptide displayed good antimicrobial activity against pathogenic fungi Candida albicans and Gram-negative bacteria Pseudomonas aeruginosa,in comparison to standard drugs griseofulvin and ciprofloxacin. Conclusion:Solution phase technique employing DCC and triethylamine(TEA) as base proved to be effective for the synthesis of natural cyclooctapeptide. N-methyl morpholine(NMM) was found to be a better base for the cyclization of linear octapeptide unit in comparison to TEA and pyridine.

关键词：循环八肽多肽化合物植物起源生物学

Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease

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Signal Transduction and Targeted Therapy 2023年第11期8卷 5159-5183页

作者： Vivek Panwar Aishwarya Singh Manini Bhatt rajiv K.Tonk Shavkatjon Azizov Agha Saquib Raza Shinjinee Sengupta Deepak kumar Manoj Garg Department of Pharmaceutical Chemistry School of Pharmaceutical SciencesShoolini UniversitySolanHimachal Pradesh173229India Amity Institute of Molecular Medicine and Stem Cell Research(AIMMSCR) Amity University Uttar PradeshSector-125NoidaUttar Pradesh201313India Department of Biomedical Engineering Indian Institute of TechnologyRoparPunjab140001India Department of Pharmaceutical Chemistry School of Pharmaceutical SciencesDelhi Pharmaceutical Sciences and Research University(DPSRU)New Delhi110017India Laboratory of Biological Active Macromolecular Systems Institute of Bioorganic ChemistryAcademy of Sciences UzbekistanTashkent100125Uzbekistan Faculty of Life Sciences Pharmaceutical Technical University100084TashkentUzbekistan rajive Gandhi Super Speciality Hospital TahirpurNew Delhi110093India

The mammalian target of rapamycin(mTOR)is a protein kinase that controls cellular metabolism,catabolism,immune responses,autophagy,survival,proliferation,and migration,to maintain cellular *** mTOR signaling cascade consists of two distinct multi-subunit complexes named mTOR complex 1/2(mTORC1/2).mTOR catalyzes the phosphorylation of several critical proteins like AKT,protein kinase C,insulin growth factor receptor(IGF-1R),4E binding protein 1(4E-BP1),ribosomal protein S6 kinase(S6K),transcription factor EB(TFEB),sterol-responsive element-binding proteins(SREBPs),Lipin-1,and Unc-51-like autophagy-activating *** signaling plays a central role in regulating translation,lipid synthesis,nucleotide synthesis,biogenesis of lysosomes,nutrient sensing,and growth factor *** emerging pieces of evidence have revealed that the constitutive activation of the mTOR pathway due to mutations/amplification/deletion in either mTOR and its complexes(mTORC1 and mTORC2)or upstream targets is responsible for aging,neurological diseases,and human ***,we provide the detailed structure of mTOR,its complexes,and the comprehensive role of upstream regulators,as well as downstream effectors of mTOR signaling cascades in the metabolism,biogenesis of biomolecules,immune responses,and ***,we summarize the potential of long noncoding RNAs(lncRNAs)as an important modulator of mTOR ***,we have highlighted the potential of mTOR signaling in aging,neurological disorders,human cancers,cancer stem cells,and drug ***,we discuss the developments for the therapeutic targeting of mTOR signaling with improved anticancer efficacy for the benefit of cancer patients in clinics.

关键词： metabolism homeostasis mTOR

Optical anisotropy and the direction of polarization of exciton emissions in a semiconductor quantum dot:Effect of heavy-and light-hole mixing

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Chinese Physics B 2017年第8期26卷 400-406页

作者： Ranber Singh rajiv kumar Vikramjeet Singh Department of Physics Sri Guru Gobind Singh CollegeSector 26Chandigarh 160019India Department of Physics DAV University JalandharPunjab 144012India IKGPTU Campus HoshiarpurPunjab 146001India

The dependence of the directions of polarization of exciton emissions, fine structure splittings （FSS）, and polarization anisotropy on the light- and heavy-hole （LH-HH） mixing in semiconductor quantum dots （QDs） is investigated using a mesoscopic model. In general, all QDs have a four-fold exciton ground state. Two exciton states have directions of polarization in the growth-plane, while the other two are along the growth direction of the QD. The LH-HH mixing does affect the FSS and polarization anisotropy of bright exciton states in the growth-plane in the low symmetry QDs （e.g., C2v, CS, C1 ）, while it has no effect on the FSS and polarization anisotropy in high symmetry QDs （e.g., C3V, D2d）. When the hole ground state is pure HH or LH, the bright exciton states in the growth-plane are normal to each other. The LH-HH mixing affects the relative intensities and directions of bright exciton states in the growth-plane of the QD. The polarization anisotropy of exciton emissions in the growth-plane of the QD is independent of the phase angle of LH-HH mixing but strongly depends on the magnitude of LH-HH mixing in low symmetry QDs.

关键词： light-heavy hole mixing excitons quantum dots