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Association of periodontal disease with glycemic control in patients with type 2 diabetes in Indian population

Frontiers of Medicine 2017年第1期11卷 110-119页

作者： Palka Kaur Khanuja Satish Chander Narula Rajesh Rajputt rajinder Kumar sharma Shikha Tewari Department of Periodontics and Oral Implantology PGIDS Post Graduate Institute of Dental Sciences Rohtak Haryana 124001 India Department of Medicine Unit VII and Endocrinology PGIMS Post Graduate Institute of Medical Sciences Rohtak Haryana 124001 India

This study aims to investigate the link between glycated hemoglobin and diabetic complications with chronic periodontitis. A total of 207 patients with type 2 diabetes and chronic periodontitis （CP） were divided according to tertiles of mean PISA （periodontal inflamed surface area） scores as low, middle and high PISA groups. Simultaneously a group of 67 periodontally healthy individuals （PH） was recruited. Periodontal examinations, including full-mouth assessment of probing depths （PPD）, bleeding on probing, clinical attachment level and plaque scores were determined. Blood analyses were carried out for glycated hemoglobin （HbA1c）, fasting plasma glucose （FPG）, 2 h post parandial glucose （PPG）. Individuals in PH group had significantly better glycemic control than CP group. Upon one-way analysis of variance, subjects with increased PISA had significantly higher HbA1c levels, retinopathy and nephropathy （P 〈 0.05）. After controlling for age, gender, body mass index （BMI）, socioeconomic status （SES）, family history of diabetes and periodontitis, duration of diabetes, the mean PISA in mm^2, PPD 4-6 mm （%） and PPD ≥7 mm （%） emerged as significant predictors for elevated HbAlc in regression model （P 〈 0.05）. Logistic regression analysis revealed that PISA was associated with higher risk of having retinopathy and neuropathy （odds ratio）. In our study, the association between glycemic control and diabetic complications with periodontitis was observed.

关键词： type 2 diabetes mellitus hemoglobin A glycated chronic periodontitis

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Arrhythmia and its risk factors post myocardial infarction:A prospective study

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Journal of Acute Disease 2022年第1期11卷 26-31页

作者： rajinder sharma Ishfaq Chowdhary Ankita sharma Department of Medicine Government Medical CollegeJammuIndia

Objectives:To determine the occurrence of arrhythmia and its associated risk factors in the first week after acute myocardial infarction(MI).Methods:A total of 100 patients with acute MI were recruited,who were followed up for one week to determine the occurrence of arrhythmia and its association with electrolyte disturbances,left ventricular ejection fraction(LVEF),and demographic *** and multivariate logistic regression was used to identify significant risk factors of ***:Among 100 cases,arrhythmia was seen in 27 *** tachycardia was the commonest,followed by ventricular premature beats and sinus *** fraction,serum calcium and magnesium were significantly different between non-arrhythmia and arrhythmia patients(P40%had a significantly lower risk of arrhythmia with an adjusted odds ratio of 0.22(95%CI:0.08 to 0.64).Conclusions:Arrhythmia is common in the first week after myocardial *** type of arrhythmia and the type of block may depend on the heart muscles involved during myocardial *** fraction is a risk factor that may affect the occurrence of arrhythmia.

关键词： Arrhythmia Myocardial infarction Left ventricular ejection fraction

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