检索结果-南通市图书馆

Pediatric UTI research: trends, collaborations, and hotspot topics - a bibliometric analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Life Research 2024年第4期7卷 9-16页

作者： Bitesh Kumar Anjan Kumar dhua Prabudh Goel Devendra Kumar Yadav Vishesh Jain Divya Jain Department of Pediatric Surgery All India Institute of Medical SciencesDelhi 110029India Department of Ophthalmology Post Graduate Institute of Child HealthNoida 201310India

Background:Urinary tract infection(UTI)is a prevalent bacterial infection affecting adults and pediatric populations,with distinct patterns observed in *** bibliometric analysis aims to provide a comprehensive overview of the research landscape in pediatric UTI from 1990 to 2022,exploring qualitative and quantitative research output,contributing authors,institutions,countries,collaborative links,and hotspot ***:This study aims to evaluate the qualitative and quantitative research output and trends in UTI in the pediatric population through a bibliometric *** analysis covers highly cited articles,contributing authors,institutes,countries,collaborative links,and future research ***:A bibliometric analysis was conducted using the Web of Science platform with a search string focused on pediatric UTI articles published between January 1990 and December *** analysis employed the Bibliometrix R-package software and VOSviewer for collaborative networks and keyword co-occurrence ***:Out of 1399 published articles,81.7%were research *** annual growth rate of publications was 4.46%.The USA led in contributions,with the University of Pennsylvania being the most productive ***"Journal of Pediatric Urology"and"Pediatric"were prominent *** AJ from the University of Toronto was the top *** networks highlighted the significance of collaboration in pediatric UTI ***:In conclusion,this bibliometric analysis provides a detailed snapshot of the research landscape in pediatric urinary tract *** 1399 articles analyzed,the study reveals a sustained interest and growth rate of 4.46%,emphasizing ongoing efforts to address pediatric UTI *** USA dominates contributions,reflecting its pivotal role in advancing *** top institutions,journals,and authors are identified,with collaborative networks *** co-occurrence networks unve

关键词： bibliometry pediatric urinary tract infection vesicoureteric reflux

Nitrosamines crisis in pharmaceuticals-Insights on toxicological implications,root causes and risk assessment:A systematic review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Pharmaceutical Analysis 2024年第5期14卷 639-652页

作者： Hemanth P.R.Vikram Tegginamath Pramod Kumar Gunjan Kumar Narasimha M.Beeraka rajashree Deka Sheik Mohammed Suhail Sandeep Jat Namitha Bannimath Gayatiri Padmanabhan Ravandur S.Chandan Pramod Kumar Bannimath Gurupadayya Department of Pharmaceutical Chemistry JSS College of Pharmacy MysuruJSS Academy of Higher Education and Research(JSSAHER)Mysuru570015India Xenone Healthcare Pvt.Ltd. New Delhi110076India Department of Pharmaceutics JSS College of Pharmacy MysuruJSS Academy of Higher Education and Research(JSSAHER)Mysuru570015India Department of Human Anatomy I.M.Sechenov First Moscow State Medical University(Sechenov University)Moscow119991Russian Federation Department of Pharmacology Raghavendra Institute of Pharmaceutical Education and Research(RIPER)Ananthapuramu515721India Herman B.Wells Center for Pediatric Research Department of PediatricsIndiana University School of MedicineIndianapolisIN46202USA Animal Physiology and Biochemistry Laboratory Department of ZoologyGauhati UniversityGuwahati781014India Department of Pharmacology JSS College of Pharmacy MysuruJSS Academy of Higher Education and Research(JSSAHER)Mysuru570015India Department of Pharmaceutical Analysis National Institute of Pharmaceutical Education and Research(NIPER)-GuwahatiChangsari781101India Department of Pharmacology University of GalwayGalwayH91 TK33Ireland

The presence of N-nitroso compounds,particularly N-nitrosamines,in pharmaceutical products has raised global safety concerns due to their significant genotoxic and mutagenic *** systematic review investigates their toxicity in active pharmaceutical ingredients(APIs),drug products,and pharmaceutical excipients,along with novel analytical strategies for detection,root cause analysis,reformulation strategies,and regulatory guidelines for *** review emphasizes the molecular toxicity of N-nitroso compounds,focusing on genotoxic,mutagenic,carcinogenic,and other physiological ***,it addresses the ongoing nitrosamine crisis,the development of nitrosamine-free products,and the importance of sensitive detection methods and precise risk *** comprehensive overview will aid molecular biologists,analytical scientists,formulation scientists in research and development sector,and researchers involved in management of nitrosamine-induced toxicity and promoting safer pharmaceutical products.

关键词： Carcinogenicity Genotoxicity Mutagenicity Molecular toxicity Nitrosamine impurities Nitrosamine drug substance-related impurities

Corrigendum to“Nitrosamines crisis in pharmaceuticals-Insights on toxicological implications,root causes and risk assessment:A systematic review”[***.14(2024)100919]

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Pharmaceutical Analysis 2024年第6期14卷 934-936页

Original statement in the Section 2:*** search Our primary screening of 180 articles yielded the relevant data for this *** selection A total of 180 articles spanning from 1960 to the present day,including original research,reviews,case reports and studies reporting nitrosamine impurities above the no-observed-adverse-effect levels(NOAEL)established by regulatory agencies,were initially *** the primary screening,we considered factors such as relevance,publication date,access to the full article text,and content.

关键词： statement initially spanning

Characterization of saline soil for the halophytes of largest inland saline wetland of India using geospatial technology

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Oceanology and Limnology 2023年第4期41卷 1277-1291页

作者： Naik rajashree Sharma LAXMI KANT Singh AVINASH Department of Environmental Science School of Earth SciencesCentral University of RajasthanBandarsindriAjmer 305817India

About 23%of the surface area and 44%of the volume of all the lakes are occupied by saline lakes in the ***,agricultural diversion,illegal encroachment,pollution,and invasive species could cause these lakes to dry up completely or partially by *** saltpan encroachment is causing Sambhar,India’s largest saline lake,to shrink by 4.23%every *** study aims to characterize the soil parameters where halophytes are growing.A literature survey was conducted for halophytes and soil *** study area was divided into four zones for stratified random *** sampling was conducted in February *** soil indicators for halophyte selected were pH,electrical conductivity,moisture,salinity,organic carbon,and organic *** obtained results were interpolated in the geospatial platform for soil characteristic *** is found that no research is conducted on halophytes of the *** on soil are also inconsistent and only six common parameters could be *** show that the pH ranged 9.37-7.66,electrical conductivity was 16.1-0.38,moisture 23.37%-1.2%,organic carbon 3.29%-0.15%,organic matter 5.6%-0.2%,and salinity 8.86%-0.72%.Though these results show improved condition as compared to last few years,in long term,the lake is *** the UN Decade of Ecosystem Restoration(2021-2030),if these causes are not addressed,the ecosystem may completely dry up.

关键词： halophytes inland lakes saline wetlands soil geospatial mapping interpolation

Multicomponent cyclodextrin system for improvement of solubility and dissolution rate of poorly water soluble drug

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Pharmaceutical Sciences 2019年第1期14卷 104-115页

作者： Mayank Patel rajashree Hirlekar Department of Pharmaceutics Bharati Vidyapeeth’s College of PharmacySector-8C.B.D.BelapurNavi Mumbai 400614MaharashtraIndia Department of Pharmaceutical Sciences and Technology Institute of Chemical TechnologyN.P.MargMatungaMumbai 400019India Department of Pharmaceutics VES College of PharmacyHashu Advani Memorial ComplexBehind Collector ColonyChembur(E)Mumbai 400074India

The purpose of the present study was to investigate the interaction of Cinnarizine(CIN)with Hydroxypropyl-β-Cyclodextrin(HPβCD)in the presence of Hydroxy Acids(HA).Various binary and ternary systems of CIN with HPβCD and HA were prepared by kneading and coevaporation *** the ternary systems,HA were tried in three different *** interaction in solution phase was studied in detail by the phase solubility method,and the solid phase interactions were characterized by Fourier Transform Infrared(FTIR)spectroscopy,Differential Scanning Calorimetry(DSC),X-Ray Diffractometry(XRD),Scanning Electron Microscopy(SEM)and Proton Nuclear Magnetic Resonance(^1H-NMR).Phase solubility revealed the positive effect of HA on the complexation of CIN with HPβ*** phase characterization confirmed the formation of inclusion complex in the ternary *** and dissolution studies illustrated that out of three different concentrations tried,HA were most effective at the 1 M concentration *** systems were very effective in improving the solubility as well as dissolution profile of CIN than the CIN–HPβCD binary ***,^1H-NMR and Molecular docking studies gave some insight at molecular level that actually which part of CIN was interacting with the HPβ*** docking and free energy calculation even enlighten the role of tartaric acid in increasing solubility of CIN in the ternary system.

关键词： Cinnarizine Hydroxypropyl-β-cyclodextrin Hydroxy acid Ternary system

An isolated duodenal perforation in pediatric blunt abdominal trauma:a rare but distinct possibility

在线全文

学校读者我要写书评

暂无评论

Burns & Trauma 2015年第1期3卷 50-53页

作者： Anjan Kumar dhua Manoj Joshi Department of Pediatric Surgery Pondicherry Institute of Medical SciencesQuarter E7PIMS Hospital CampusPondicherry 605014India

Isolated duodenal perforation(IDP)in pediatric trauma is rarely *** most of the children with blunt trauma are managed expectantly,timely diagnosis is imperative to avoid morbidity and *** report a case of IDP and emphasize on certain specific clinical features indicating possibility of duodenal *** also stress upon the role of early contrast-enhanced computerized tomography(CECT)in such cases.

关键词： Blunt trauma abdomen Duodenorrhaphy Isolated duodenal perforation Pediatric trauma

Phytochemical profiling of Artocarpus lakoocha Roxb. leaf methanol extract and its antioxidant, antimicrobial and antioxidative activities

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2019年第11期9卷 484-492页

作者： Ekta Bhattacharya rajashree Dutta Swati Chakraborty Suparna Mandal Biswas Agricultural and Ecological Research Unit Indian Statistical Institute203B.T.RoadKolkata 700108India Guru Nanak Institute of Pharmaceutical Science&Technology Panihati Kolkata 700114India

Objective:To explore the phytochemical profile of Artocarpus lakoocha *** both qualitatively and quantitatively,and validate its role as a potent antioxidant and antimicrobial ***:Extraction and isolation of different compounds were done from the leaves of Artocarpus lakoocha based on solvent fractionation ***,quantitative and qualitative phytochemical profiling along with antioxidant,antimicrobial and antioxidative activities were tested following standard ***:Among the five fractions,methanol fraction of Artocarpus lakoocha exhibited higher content of phytochemical compounds[phenols=(3175.21±290.43)mg GAE/g dry extract,flavonoids=(1173.15±47.52)mg QE/g dry extract and tannins=(923.53±95.21)mg TAE/g dry extract]as compared to other *** methanol fraction showed the highest antioxidant activity in DPPH and ABTS radical scavenging assays with IC50 of(111.98±34.20)μg/mL and(138.26±0.66)μg/mL,respectively,and the best reduction potential with a value of(316.81±2.96)mg QE/g dry extract in reducing power *** was significant correlation between the amount of phytochemicals and antioxidant ***,the extract successfully protected Lambda phage DNA from damage at 5 and 6 mg/mL concentration and exhibited substantial bactericidal as well as fungicidal *** GC-MS analysis of methanol fraction of Artocarpus lakoocha revealed diethyl phthalate as the main phytochemical compound,along with 3,4-dihydroxymandelic acid,9-octyl eicosane and 7,8-didehydro-3-methoxy-17-methyl-6-methylene ***:The methanol fraction of Artocarpus lakoocha could be used as a potent antioxidant and antimicrobial agent for sustainable agriculture and pharmaceutical purposes.

关键词： Moraceae Bioactive compounds Natural pharmaceuticals Diethyl phthalate

Animal models in the study of Alzheimer's disease and Parkinson's disease:A historical perspective

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Animal Models and Experimental Medicine 2022年第1期5卷 27-37页

作者： rajashree Banerjee Arushi Rai Shreyas M.Iyer Sonia Narwal Meghana Tare Department of Biological Sciences Birla Institute of Technology and SciencePilaniIndia

Alzheimer's disease and Parkinson's disease are two of the most prevalent and disabling neurodegenerative diseases *** are proteinopathic conditions and while occasionally inherited,are largely sporadic in *** the advances in our understanding of the two have been significant,they are far from complete and neither diagnosis nor the current practices in treatment and rehabilitation is adequately *** models have historically found application as testing beds for novel therapeutics and continue to be valuable aids in pharmacological *** review chronicles the development of those models in the context of Alzheimer's and Parkinson's disease,and highlights the shifting paradigms in studying two humanspecific conditions in non-human organisms.

关键词： Alzheimer's disease animal models neurodegeneration Parkinson's disease

Visible light photocatalytic dye decomposition behaviour of solid state reaction grown Zn_2TiO_4 nanoparticles

在线全文

学校读者我要写书评

暂无评论

Journal of Semiconductors 2018年第12期39卷 32-37页

作者： Lizina Khatua rajashree Sahoo Pravakar Satapathy Rudrashish Panda Susanta Kumar Das School of Electronics Engineering KIIT Deemed to be University Department of Physics School of Applied Sciences KIIT Deemed to be University

In this investigation, visible photocatalytic dye decomposition is carried out with compound semiconductor nanoparticles of zinc orthotitanate(Zn2TiO4). These nanoparticles were grown by the solid state reaction method and characterized by field emission scanning electron microscopy, transmission electron microscopy, Xray diffraction,diffuse reflectance spectroscopy,photoluminescence study, and Brunauer-Emmett-Teller(BET)study. The BET surface area of the Zn2TiO4nanoparticles was found to be 8.78 m2/g. The photocatalytic activity is carried out by using a 500 W halogen light source having a spectrum in the range of 450 to 860 nm and the reaction kinetics was found to be the pseudo first order. The reaction rate constant was found to be 0.069 min-1. Discussion is given on the possible mechanism of the observed visible photocatalytic dye decomposition activity. The cost of the material used is very low, so it could be very useful for visible photocatalytic dye decomposition.

关键词： visible photocatalysis dye decomposition nanoparticles zinc orthotitanate solid state reaction