检索结果-南通市图书馆

Triple drug combin.tion.of telmisartan. amlodipin. an. hydrochlorothiazide in.the treatmen. of essen.ial hyperten.ion

引用

Open.Journ.l of In.ern.l Medicin. 2012年第2期2卷 67-71页

作者： Man.sh Maladkar Vijay Kumar Verma Keshav A. n.rsikar rajan D. Walin.kar W. R. Patil n. J. S. Saggu Suresh P. Kulkarn. 8 Shalom Navi Mumbai India Agarwal Hospital Thane (West) India Clin.c 411 Jack Chambers Navi Mumbai India Head-Medical & Regulatory Affairs Aristo Pharmaceuticals Pvt Ltd Mumbai India Jn.2/47/P2 Navi Mumbai India shree Polyclin.c 114 Nirman Vyapar Kendra Navi Mumbai India Yash Speciality Clin.c Nirman Vyapar Kendra Navi Mumbai India

Backgroun.: Triple drug therapy comprisin. an.ioten.in.receptor blocker (ARB), calcium chan.el blocker (CCB) an. hydrochlorothiazide (HCT) effectively con.rols essen.ial hyperten.ion.as eviden. from the literature. This study was un.ertaken.to assess the efficacy an. safety of triple combin.tion.compared to the dual drug therapy. Methodologies: A total of 220 male an. female patien.s with essen.ial hyperten.ion.were en.olled in.the study. The patien.s were divided in.o two groups. Group A received a bilayer tablet of FDC of Telmisartan.+ Amlodipin. + HCT an. group B received FDC tablet of Telmisartan.+ HCT. Both the treatmen.s were admin.stered on.e daily for twelve weeks. The patien.s were asked to follow-up on.week 1, 2, 4, 6, 8 an. 10 for periodic efficacy an. safety evaluation.. Effect on.systolic blood pressure (SBP), diastolic blood pressure (DBP) an. quality of life (QOL) were recorded durin. the course of the trial. Results: Blood pressure reduction.(BP) to the desired goals was observed with both the treatmen.s. The SBP an. DBP reduction. were superior in.triple combin.tion.therapy than.double combin.tion. Both treatmen.s improved QOL of patien.s. Con.lusion. Triple drug combin.tion.of telmisartan. amlodipin. an. HCT may serve a poten.ial role in.achievin. desired BP goals, in.patien.s with essen.ial hyperten.ion. which are otherwise poorly man.ged by either mon.therapy or dual drug therapy.

关键词： Essen.ial Hyperten.ion Telmisartan Amlodipin. an. HCT

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Leakage Reduction.Usin. DTSCL an. Curren. Mirror SCL Logic Structures for LP-LV Circuits

引用

Circuits an. Systems 2013年第1期4卷 20-28页

作者： San.eev Rai Ram Awadh Mishra Sudarshan.tiwari Departmen. of Electron.cs & Commun.cation.En.in.erin. M.N.N.I.T Allahabad India n.tion.l In.titute of Techn.logy Raipur India

This paper presen.s a n.vel approach to design.robust Source Coupled Logic (SCL) for implemen.in. ultra low power circuits. In.this paper, we propose two differen. source coupled logic structures an. an.lyze the performan.e of these structures with STSCL (Sub-threshold SCL). The first design.un.er con.ideration.is DTPMOS as load device which an.lyses the performan.e of Dyn.mic Threshold SCL (DTSCL) Logic with previous source coupled logic for ultra low power operation. DTSCL circuits exhibit a better power-delay Performan.e compared with the STSCL Logic. It can.be seen.that the proposed circuit provides 56% reduction.in.power delay product. The secon. design.un.er con.ideration.uses basic curren. mirror active load device to provide required voltage swin.. Curren. mirror source coupled logic (CMSCL) can.be used for high speed operation. The advan.age of this design.is that it provides 54% reduction.in.power delay product over con.en.ion.l STSCL. The main.drawback of this design.is that it provides a higher power dissipation.compared to other source coupled logic structures. The proposed circuit provides lower sen.itivity to temperature an. power supply variation. with a superior con.rol over power dissipation. Measuremen.s of test structures simulated in.0.18 μm CMOS techn.logy shows that the proposed DTSCL logic con.ept can.be utilized successfully for bias curren.s as low as 1 pA. Measuremen.s show that existin. stan.ard cell libraries offer a good solution.for ultra low power SCL circuits. Caden.e Virtuoso schematic editor an. Spectre Simulation.tools have been.used.

关键词： CMOS In.egrated Circuits CMOS Logic Circuit Dyn.mic Threshold MOS (DTMOS) Power-Delay Product Source-Coupled Logic (SCL) Sub-Threshold CMOS Sub-Threshold SCL Ultra-Low-Power Circuits Weak In.ersion LP-LV(Low Power-Low Voltage)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

尼泊尔桑可西河流域新格地子流域滑坡评价

引用

Journ.l of Resources an. Ecology 2024年第2期15卷 431-438页

作者： BASn.T Bhuwan.JOshI Rajeev shARMA Ram Prasad SUBEDI rajan 特里布万大学林业研究所(博卡拉校区) 尼泊尔博卡拉33700 尼泊尔农林大学自然资源管理学院林学系尼泊尔卡塔里56310

山体滑坡是尼泊尔山区的主要灾害,主要是由于其脆弱的地貌、强烈的降雨、不当的土地管理和在修建山区道路过程中没有采取必要的稳定措施所导致的。由于频繁的山体滑坡,下游地区人类的生命财产遭受了巨大损失,并导致生态系统生产力和功... 详细信息

山体滑坡是尼泊尔山区的主要灾害,主要是由于其脆弱的地貌、强烈的降雨、不当的土地管理和在修建山区道路过程中没有采取必要的稳定措施所导致的。由于频繁的山体滑坡,下游地区人类的生命财产遭受了巨大损失,并导致生态系统生产力和功能下降,河道泥沙淤积。土地利用与土地覆被、地形、道路、排水、地质环境和降雨等多种空间因素与滑坡的发生紧密相关,并决定了该地区滑坡的易感性。了解滑坡现象及其引发的相关因素,对于采取适当的预防、控制和恢复措施至关重要。本研究在尼泊尔桑科西河流域的新格地子流域进行,旨在了解滑坡危害、引发的相关因素以及为最大限度地减少可能的危害而采取的最佳预防策略。滑坡评估是通过使用时序谷歌影像和实地调查,对滑坡体进行识别和数字化来进行的。利用GIS软件对滑坡危险性进行评估,编制影响因子图,并对现场观测数据进行分析的基础上,计算了滑坡的规模。此外,在相关家庭的问卷调查(n.60)中,进行目的性抽样,探讨人们对山体滑坡、对生计资产的主要影响因素的看法。并采用Friedman.参数检验评估滑坡对当地人感知的最主要影响因素。根据现场调查,在研究区域的不同位置共调查了46处滑坡体,滑坡总面积为4.77km^(2)。通过使用Friedman.验的比较矩阵分析,本研究确定了滑坡发生的主要原因是农村道路、施工、边坡因素、降雨和土地利用与土地覆被。距离道路200-500 m造成最高比率的滑坡灾害,东南方向坡度30°-45°的山体对滑坡的易感性最高。与其他土地利用相比,因为在林内松软地区修建道路,茂密的森林更易受到山体滑坡的影响。比较道路建设前后滑坡的影响,约80%的受访者认为对滑坡有重要影响。

关键词：滑坡灾害滑坡评估滑坡因素分析

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Models an. Algorithms for Diffuse Optical Tomographic System

引用

In.ern.tion.l Journ.l of Commun.cation., n.twork an. System Scien.es 2013年第12期6卷 489-496页

作者： Samir Kumar Biswas rajan Kan.irodan.Ram Mohan.Vasu Departmen. of In.trumen.ation.an. Applied Physics Indian Institute of Science Bangalore India Departmen. of Physics Indian Institute of Science Bangalore India

Diffuse optical tomography (DOT) usin. n.ar-in.rared (n.R) light is a promisin. tool for n.n.n.asive imagin. of deep tissue. The approach is capable of recon.tructin. the quan.itative optical parameters (absorption.coefficien. an. scatterin. coefficien.) of a soft tissue. The motivation.for recon.tructin. the optical property variation.is that it an., in.particular, the absorption.coefficien. variation. can.be used to diagn.se differen. metabolic an. disease states of tissue. In.DOT, like an. other medical imagin. modality, the aim is to produce a recon.truction.with good spatial resolution.an. in.con.rast with n.isy measuremen.s. The parameter recovery kn.wn.as in.erse problem in.highly scatterin. biological tissues is a n.n.in.ar an. ill-posed problem an. is gen.rally solved through iterative methods. The algorithm uses a forward model to arrive at a prediction.flux den.ity at the tissue boun.ary. The forward model uses light tran.port models such as stochastic Mon.e Carlo simulation.or determin.stic methods such as radioactive tran.fer equation.(RTE) or a simplified version.of RTE n.mely the diffusion.equation.(DE). The fin.te elemen. method (FEM) is used for discretizin. the diffusion.equation. The frequen.ly used algorithm for solvin. the in.erse problem is n.wton.based Model based Iterative Image Recon.truction.(n.MoBIIR). Man. Varian.s of Gauss-n.wton.approaches are proposed for DOT recon.truction. The focuses of such developmen.s are 1) to reduce the computation.l complexity;2) to improve spatial recovery;an. 3) to improve con.rast recovery. These algorithms are 1) Hessian.based MoBIIR;2) Broyden.based MoBIIR;3) adjoin. Broyden.based MoBIIR;an. 4) pseudo-dyn.mic approaches.

关键词： Diffuse Optical Tomography Gauss n.wton Methods Broyden an. Adjoin. Broyden Approaches Pseu-do-Dyn.mic Method

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessmen. of Fin. Structure Processin. Strategies in.Un.laterally Deafen.d Cochlear Implan. Users

引用

In.ern.tion.l Journ.l of Otolaryn.ology an. Head & n.ck Surgery 2014年第6期3卷 347-353页

作者： Dayse Távora-Vieira Gun.sh P. rajan Otolaryn.ology Head & Neck Surgery School of Surgery University of Western Australia Perth Australia Freman.le Hospital Fremantle Australia

This study aimed to in.estigate the speech perception.an. subjective preferen.e of un.laterally deafen.d cochlear implan. users for two differen. speech codin. strategies. Thirteen.subjects who received a cochlear implan. were provided with 2 maps that differed in.the speech codin. strategy, FS4 or FS4-p (MED-EL). Subjects were requested to altern.te between.the two maps daily for two weeks an. to complete a question.aire daily. Speech perception.testin. was performed usin. the adaptive Bamford-Kowal-Ben.h speech-in.n.ise test (BKB-SIn. after two weeks of altern.tin. FS4/FS4-p use. The subjective ben.fit of FS4-p was sign.fican.ly greater than.the subjective ben.fit of FS4 on.all five question. of the question.aire. There was a sign.fican. improvemen. in.speech perception.scores over time un.er the S0/n., S0/n.E, SCI/n.E test con.ition.. There was n. sign.fican. differen.e between.the speech perception.scores obtain.d with FS4 an. FS4-p codin. strategies. For this group of cochlear implan. recipien.s, assessmen. of the subjective preferen.e for the speech codin. strategy is likely to en.an.e motivation. complian.e an. con.equen.ly, outcomes.

关键词： CI Un.lateral Deafn.ss FS4 FS4-p

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The delivery of n.myc down.tream-regulated gen. 2(n.RG2)self-amplifyin. mRn. via modified lipid n.n.particles as a poten.ial treatmen. for drug-resistan. an. metastatic can.ers

引用

Medical Review 2024年第3期4卷 235-238页

作者： San.ra E.Rezn.k Amit K.tiwari Vivek Chavda Charles R.Ashby Jr. Departmen. of Pharmaceutical Scien.es College of Pharmacy and Health SciencesSt.John’s UniversityQueensUSA Departmen.s of Pathology an. Obstetrics an. Gyn.cology an. Women.s Health Montefiore Medical Center/Albert Einstein College of MedicineBronxUSA Departmen. of Pharmaceutical Scien.es College of Pharmacy University of Arkansas for Medical Sciences Little RockUSA Departmen. of Pharmaceutics an. Pharmaceutical Techn.logy L.M.College of Pharmacy AhmedabadIndia Departmen. of Pharmaceutical Scien.es College of Pharmacy and Health SciencesSt.John’s UniversityQueensNY 11439USA

The protein.n.myc down.tream-regulated gen. 2(n.RG2),a tumor suppressor,is sign.fican.ly decreased or absen. in.man. types of *** is a sign.fican. n.gative correlation.between.the levels of n.RG2 an. the developmen. an. progression.of can.er tumor recurren.e an. tumor in.asion.in.differen. *** con.rast,the in.vitro an. in.vivo overexpression.of the n.RG2 protein.decreases the proliferation.growth,adhesion.an. migration.of man. types of can.er *** in.vitro overexpression.of n.RG2 in.reases the efficacy of certain.an.ican.er drugs in.specific types of can.er *** hypothesize that the delivery of the mRn. of the n.RG2 protein.en.apsulated by lipid n.n.particles,could represen. a poten.ial treatmen. of metastatic an. drug-resistan. *** would be accomplished usin. a self-amplifyin. mRn. that en.odes the n.RG2 protein.an. an.Rn.-depen.en.-Rn. polymerase,obtain.d from an.in.vitrotran.cribed(IVT)*** IVT mRn. would be en.apsulated in.a lipid *** efficacy of the n.n.formulation.would be determin.d in.cultured can.er cells an. if the results are positive,n.de mice tran.plan.ed with either drug-resistan. or metastatic drug-resistan. can.er cells,would be treated with the n.n.formulation.an. mon.tored for efficacy an. adverse *** the appropriate preclin.cal studies in.icate this formulation.is efficacious an. safe,it is possible it could be evaluated in.clin.cal trials.

关键词： n.myc down.tream-regulated gen. 2(n.RG2) can.er self-amplifyin. mRn. n.n.particle

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Poten.ial Bioeffects of Extremely Low Frequen.y Electromagn.tic Fields on.Melaton.n.Levels &Related Oxidative Stress in.Electric Utility Workers Exposed to 132 kV Substation

引用

Journ.l of Electromagn.tic An.lysis an. Application. 2013年第11期5卷 393-403页

作者： Ravin.ra tiwari Suresh Chan.ra Bhargava Yog Raj Ahuja Departmen. of Electrical an. Electron.c En.in.erin. Sree Nidhi Institute of Science and Technology Hyderabad India Gen.tics Un.t Vasavi Medical and Research Centre Hyderabad India Un.versity Gran.s Commission.(UGC) Research Un.t Bhavan’s New Science College Hyderabad India

Electricity substation. take electricity from power lin.s an. tran.former lin.s to tran.form it from high to low voltage an. distribute to the con.umers. These substation. gen.rate low frequen.y electromagn.tic fields similar to those emitted from over head power lin.s an. electrical applian.es at home. The presen. study is focused on.assessin. the poten.ial bioeffects of Extremely Low Frequen.y Electromagn.tic Fields (ELF-EMFs) on.melaton.n.level an. oxidative stress biomarkers, in.subjects occupation.lly exposed to 132 kV high voltage substation.in.Hyderabad, In.ia. These subjects are in.olved in.main.en.n.e an. in.tallation.of power lin. distribution.at electricity tran.mission.n.twork. The ELFEMFs exposed subjects (n.= 142) in.luded the electric utility workers, who were compared with age, an. socioecon.mic status matched con.rols (n.= 151). The subjects were profession.lly categorized based on.their job titles, with differen. exposure levels, as admin.strative workers (low exposure), main.en.n.e workers (medium exposure) an. livelin. workers (high exposure). The plasma melaton.n.levels were sign.fican.ly suppressed in.the high exposed subjects i.e., hotlin. workers (p 0.05). The oxidan. status levels of plasma Malon.ialdehyde (MDA) an. n.tric Oxide (n.) showed sign.fican.ly in.reased levels in.all the exposed subjects (p 0.05). The activity levels of erythrocyte an.ioxidative en.yme when.compared to con.rol subjects were sign.fican.ly reduced in.the exposed subjects of all the categories (p 0.05).

关键词： Melaton.n Oxidative Stress 132 kV Live-Lin. Workers

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

氢气含量对铝合金铸件中缩孔缺陷的影响

引用

铸造 1987年第10期 34-35页

作者： S.n.tiwari 牛小平

用一系列含有不同量氢气的Al-Cu和Al-Si合金,在不设置冒口的条件下,铸造两端呈锥形的圆柱形铸件。发现,为防止铸件中的缩孔缺陷,而形成弥散分布的气孔,需要向熔融金属中引入一定量的氢气。该量取决于合金的成分及与合金的液相线温度有关。

关键词：缩孔缺陷弥散分布铸件铝合金轻有色金属合金合金系气孔氢气含量

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Perovskite solar cell operation.l stability un.er vacuum for space application

Perovskite solar cell operational stability under vacuum for...

引用

第七届新型太阳能电池材料科学与技术学术研讨会

作者： Yan.Jian. shih-Chi Yan. Stefan. Pison. Thierry Moser Fan.Fu Ayodhya n.tiwari Laboratory for Thin.Films an. Photovoltaics Empa–Swiss Federal Laboratories for Material Science and Technology

High power con.ersion.efficien.y,high specific power(W/g) an. stowed packin. efficien.y(W/cm

关键词： perovskite solar cell stability vacuum degradation

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Extraction.an. En.ichmen. of Copper by Liquid Emulsion.Membran. Usin. LIX 664n

引用

Journ.l of En.iron.en.al Protection 2014年第17期5卷 1611-1617页

作者： Rashmi Kumar Dahyalal J. shah Krishn. Kan. tiwari D. J. San.hvi College of En.in.erin. Mumbai India Mukesh Patel School of Techn.logy Man.gemen. & En.in.erin. (n.IMS) Mumbai India Jaypee Un.versity of En.in.erin. an. Techn.logy (Gun.) Madhya Pradesh India

Process in.en.ification.usin. liquid emulsion.membran.s (LEMs) for extraction.of copper has been.studied in.this work. In.LEM process the extraction.an. strippin. processes are combin.d in.on. stage. The solubility of the solute or the chemical affin.ty between.the solute an. carrier reagen. in.the membran. results in.the separation.of the solute from the feed mixture. In.this work the membran. phase comprised of LIX 664n.as the extractan. dissolved in.kerosen. an. Span.80 as surfactan.. The strippin. phase was sulfuric acid with 180 g/l con.en.ration.an. feed phase had copper con.en.ration.of 3.5 g/l. Effect of various process parameters such as batch con.act time, speed of agitation. W:O ratio an. treat ratio has been.experimen.ally in.estigated to get better in.ight of the process. The maximum en.ichmen. of copper in.the in.ern.l phase obtain.d was 11.6 times with batch con.act time of 10 min.tes, agitation.speed of 300 rpm an. treat ratio of 6:1.

关键词： Extraction En.ichmen. Liquid Emulsion Membran.s LIX 664n Copper

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：