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Histopathological studies and oxidative stress of synthesized silver nanoparticles in Mozambique tilapia (Oreochromis mossambicus)

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Journal of Environmental Sciences 2012年第6期24卷 1091-1098页

作者： rajakumar govindasamy Abdul Abdul Rahuman Unit of Nanotechnology and Bioactive Natural Products Post Graduate and Research Department of ZoologyC.Abdul Hakeem CollegeMelvisharam-632509Vellore DistrictTamil NaduIndia

To evaluate the potential environmental effects of engineered nano metals,it is important to determine the adverse effects of various nanomaterials on aquatic *** tilapia （Oreochromis mossambicus） were maintained in 10 L glass aquaria,and exposed to a graded series of synthesized silver nanoparticles （Ag-NPs） at 25,50 and 75 mg/L for eight *** LC 50 value was 12.6 mg/*** activities of antioxidant enzymes and the contents of antioxidants were lowered in the gills and liver of fishes treated with AgNPs,which resulted in heavy accumulation of free *** results imply that the balance between the oxidative and antioxidant system in the fish was broken down during Ag-NPs *** principal concern related with the release of nanomaterials and their smaller particle may change the materials transport and potential toxicity to aquatic organisms compared to larger particles.

关键词： silver nanoparticles Oreochromis mossambicus oxidative stress analysis histopathological studies toxic effect

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Larvicidal activity of green synthesized silver nanoparticles using bark aqueous extract of Ficus racemosa against Culex quinquefasciatus and Culex gelidus

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Asian Pacific Journal of Tropical Medicine 2013年第2期6卷 95-101页

作者： Kanayairam Velayutham Abdul Abdul Rahuman govindasamy rajakumar Selvaraj Mohana Roopan Gandhi Elango Chinnaperumal Kamaraj Sampath Marimuthu Thirunavukkarasu Santhoshkumar Moorthy Iyappan Chinnadurai Siva Unit of Nanotechnology and Bioactive Natural Products Post Graduate and Research Department of ZoologyC.Ahdul Hakeem CollegeMelvisharam-632 509Vellore DistrictTamil NaduIndia Organic & Medicinal Chemistry Research Laboratory Organic Chemistry DivisionSchool of Advanced SciencesVIT UniversityVellore-632 014Tamil NaduIndia Unit of Nanotechnology and Bioactive Natural Products Post Graduate and Research Department of ZoologyC.Abdul Hakeem CollegeMelvisharam-632 509Vellore DistrictTamil NaduIndia

Objective:To investigate the larvicidal activity of synthesized silver nanoparticles（Ag NPs） utilizing aqueous bark extract of Ficus racemosa（***） was tested against fourth instar larvae of filariasis vector,Culex quinquefasciatus（***） and japanese encephalitis vectors,Culex gelidus（***）.Methods:The synthesized Ag NPs was characterized by UV-vis spectrum,X-ray diffraction（XRD）,Scanning electron microscopy（SEM） and Fourier transform infrared（FTIR）.The larvicidal activities were assessed for 24 h against the larvae of *** and *** with varying concentrations of aqueous bark extract *** and synthesized Ag ***50 and r2 values were ***:The maximum efficacy was observed in crude aqueous extract of *** against the larvae of *** and ***(LC50=67.72 and 63.70 mg/L;r2=0.995 and 0.985) and the synthesized Ag NPs(LC50=12.00 and 11.21 mg/L;r2=0.997 and 0.990).*** Ag NPs showed the XRD peaks at 2θvalues of 27.61,29.60,35.48,43.48 and 79.68 were identified as （210）,（121）,（220）,（200） and（311） reflections,*** FTIR spectra of Ag NPs exhibited prominent peaks at 3 425,2 878,1 627 and 1 382 in the region 500-3 000 cm-1.The peaks correspond to the presence of a stretching vibration of（NH） C=O *** analysis showed shape in cylindrical,uniform and rod with the average size of 250.60 ***:The biosynthesis of silver nanoparticles using bark aqueous extract of *** and its larvicidal activity against the larvae of disease spreading *** maximum larvicidal efficacy was observed in the synthesized Ag NPs.

关键词： Ficus racemosa Culex quinquefasciatus Culex gelidus Electron microscopic study

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Green synthesis of titanium dioxide nanoparticles using Psidium guajava extract and its antibacterial and antioxidant properties

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Asian Pacific Journal of Tropical Medicine 2014年第12期7卷 968-976页

作者： Thirunavukkarasu Santhoshkumar Abdul Abdul Rahuman Chidambaram Jayaseelan govindasamy rajakumar Sampath Marimuthu Arivarasan Vishnu Kirthi Kanayairam Velayutham John Thomas Jayachandran Venkatesan Se-Kwon Kim Unit of Nanotechnology and Bioactive Natural Products Post Graduate and Research Department of ZoologyC.Abdul Hakeem CollegeMelvisharam-632509Vellore DistrictTamil NaduIndia Centre for Nanobiotechnology VIT UniversityVellore 632014.Tamil NaduIndia Department of Chemistry Pukyong National UniversityBusan-608737Republic of Korea

Objective:To determine the efficacies of antibacterial and antioxidant activities of aqueous leaf extract of Psidium guajava mediated biosynthesis of titanium dioxide nanoparticles(TiO_2,NPs).Methods:Synthesized TiO_2 NPs were tested by disc diffusion method against against human pathogenic *** total antioxidant activity and phenolic content(Folin—Ciocalteau method) of synthesized TiO_2 NTs and aqueous plant extract were *** scavenging radicals were estimated hv DPPH *** synthesized TiO_2 NPs were characterized by XRD,*** and EDX,Results:FTIR spectra of synthesized TiO_2 NPs exhibited prominent peaks at 3410 cm^(-1)(alkynes),1 578 cm^(-1).1 451 cm^(-1)(alkanes),and 1 123 cm^(-1)(C-O absorption).The morphological characterization of synthesized TiO_2 NPs was analysed by FESEM which showed spherical shape and clusters with an average size of 32.58 *** maximum zone of inhibition was observed in the synthesized TiO_2 NPs(20 μg/mL) against Staphylococcus aureus(25 mm) and Escherichia coli(23 mm).The synthesized TiO_2 NPs showed more antibacterial activity than the standard antibiotic disk,tetracycline which drastically reduces the chances for the development of antibiotics resistance of bacterial *** plant aqueous extract and synthesized TiO_2NPs were found to possess maximum antioxidant activity when compared with ascorbic *** content of phenolic compounds(mg/g) in Leaf aqueous extract and synthesized TiO_2 NPs were found to be 85.4 and 18.3 mgTA/g,***:Green synthesized TiO_2 NPs provides a promising approach can satisfy the requirement of large-scale industrial production hearing the advantage of low—cost,eco—friendly and reproducible.

关键词： TiO2 nanoparticles Psidium guajava FTIR Electron microscopy Antibacterial activity Antioxidant activity

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