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Traumatic Vitreous Hemorrhage in Children-Clinical Features and Outcomes

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Eye Science 2014年第2期29卷 63-69页

作者： Aditya Sudhalkar Jay Chhablani Subhadra Jalali raja narayanan Smt Kannuri Santhamma Centre for Vitreoretinal Services LV Prasad Eye Institute

Purpose: To determine the clinical profile, causes, and outcomes of traumatic vitreous hemorrhage(TVH) in children(<18 years of age).Methods:.Retrospective computer assisted chart review..501 eyes of 464 children(103 females; 361 males) who presented with TVH between 2001 and 2012 were included. All children underwent a complete ocular and systemic examination and investigation. The etiology, visual, and anatomic results of pediatric TVH were the outcome ***: Median age: 12.27±4.51 years. 37 patients had bilateral VH; 43.24% of these were firecracker injuries..Commonest complaint was diminished vision(96.45%)..Mean BCVA(logMAR) at presentation was 2.64±1.11 logMAR. Sticks(43.43%).and cricket balls.(13.24%).were the commonest causes..Treatment included medical therapy(topical and / or systemic; 56 eyes), laser photocoagulation(34 eyes), and /or surgery.(387 eyes)..Mean final BCVA was significantly better(1.01±0.58 logMAR;P=0.011,Z test). Mean follow up in the closed and open globe trauma was 47±12.47 and 36.24±9.72 months, ***:.TVH has significant implications in *** injuries are notorious for bilateral VH.

关键词：临床特点玻璃体外伤性儿童出血预后药物治疗外科手术

Response of L V Prasad Eye Institute to COVID-19 outbreak in India:experience at its tertiary eye care centre and adoption to its Eye Health Pyramid

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International Journal of Ophthalmology(English edition) 2021年第1期14卷 1-9页

作者： Rohit C Khanna Prashant Garg Pravin K Vaddavalli Merle Fernandes Suryasnata Rath Sameera Nayak raja narayanan Rajeev Reddy Pappuru Swathi Kaliki Anthony Vipin Das Savitri Sharma Subhadra Jalali Allen Foster Community Eye Health Research Centre Gullapalli Pratibha Rao International Centre for Advancement of Rural Eye CareL V Prasad Eye InstituteHyderabad 500030India Brien Holden Eye Research Centre L V Prasad Eye InstituteHyderabadTelangana 500034India School of Optometry and Vision Science University of New South WalesSydney 2033Australia University of Rochester School of Medicine and DentistryRochesterNY 14642USA Kallam Anji Reddy Campus L V Prasad Eye InstituteHyderabad 500034India Grandhi Mallikarjun Rao Varalakshmi Campus L V Prasad Eye InstituteVishakhapatnamAndhra Pradesh 530040India Mithu Tulsi Chanrai Campus L V Prasad Eye InstituteBhubaneswaraOdisha 751024India Kode Venkatadri Chowdary Campus L V Prasad Eye InstituteVijayawada 521134India Department of eyeSmart EMR&AEye L V Prasad Eye Institute 500034India

AIM:To summarize the experience of response to COVID-19 outbreak at a tertiary eye care institute and its network of health facilities in ***:Our responses are based on the principles of social distancing,hand hygiene,respiratory etiquettes,surface disinfection protocol,and rational use of appropriate personal protective equipment(PPE).We describe our response in terms of administrative controls,clinical protocols,staff protection,environmental controls,and social distancing *** also discuss our communication strategies and monitoring systems,to ensure compliance to ***:Administrative control is mainly related to formation of task force and its *** protocols are related to patient triaging methods and clinical examination guidelines in Outpatient,Inpatient and Operating *** protection is focused on training staff on the protocols to be followed in hospital as well as at home,and use of *** protocol is focused on cleaning and disinfectant methods to be used in the *** addition,there are systems for communication as well as monitoring compliance to ***:We hope that these protocols and our experience would help the ophthalmic community globally and serve as a guide to protect ophthalmologists and ophthalmic care personnel,and their patients across the world.

关键词： COVID-19 coronavirus India ophthalmology pandemic care practices pandemic protocols eye care

Appropriate Sub-band Selection in Wavelet Packet Decomposition for Automated Glaucoma Diagnoses

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International Journal of Automation and computing 2015年第4期12卷 393-401页

作者： Chandrasekaran raja narayanan Gangatharan Department of Electronics and Communication Engineering Anjalai Ammal Mahalingam Engineering College Department of Electronics and Communication Engineering R.M.K.College of Engineering and Technology

The most common reason for blindness among human beings is *** increase of fluid pressure damages the optic nerve which gradually leads to irreversible loss of vision.A technique for automated screening of Glaucoma from the fundal retinal images is presented in this *** paper intends to explore the significance of both the approximate and detail coefficients through wavelet packet decomposition(WPD).Decomposition is done with "db3" wavelet function and the images are decomposed up to level-3producing 84 *** features,the energy and the entropy are calculated for each sub-band producing two feature matrices(158 images × 84 features).The above step is purely a statistical measure based on *** enhance the diagnostic accuracy,the second phase considers the structural(biological) region of interest(ROI) in the image and then extracts the same *** is worthy to note that direct biological features are not extracted to eliminate the drawbacks of segmentation whereas the biologically significant region is taken as ***,the detailed coefficient sub-bands(prominent edges) show more significance in the biological-ROI *** from enhancing the diagnostic accuracy by feature reduction,the paper intends to mark the significance indices,uniqueness and discrimination capability of the significant features(sub-bands) in both the ***,the crisp inputs are fed to the classifier ***,from the significant features of the biological-ROI feature matrices,the accuracy is raised to 85%which is notable than the accuracy of 79%achieved without considering the ROI.

关键词： Glaucoma wavelet packet decomposition feature reduction feature significance artificial neural networks.

Endothelial dysfunction in the kidney transplant population:Current evidence and management strategies

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World Journal of Transplantation 2025年第1期15卷 24-43页

作者： Arun Prabhahar Akshey Batta Juniali Hatwal Vivek Kumar raja Ramachandran Akash Batta Department of Telemedicine(Internal Medicine and Nephrology) Post Graduate Institute of Medical Education and ResearchChandigarh 160012India Department of Urology and Renal Transplant Neelam HospitalRajpura 140401PunjabIndia Department of Internal Medicine Post Graduate Institute of Medical Education and ResearchChandigarh 160012India Department of Nephrology Post Graduate Institute of Medical Education and ResearchChandigarh 160012India Department of Cardiology Dayanand Medical College and HospitalLudhiana 141001PunjabIndia

The endothelium modulates vascular homeostasis owing to a variety of vasoconstrictors and *** dysfunction(ED),characterized by impaired vasodilation,inflammation,and thrombosis,triggers future cardiovascular(CV)*** kidney disease,a state of chronic inflammation caused by oxidative stress,metabolic abnormalities,infection,and uremic toxins damages the *** is also associated with a decline in estimated glomerular filtration *** kidney transplantation,endothelial functions undergo immediate but partial restoration,promising graft longevity and enhanced CV ***,the anticipated CV outcomes do not happen due to various transplant-related and unrelated risk factors for ED,culminating in poor CV health and graft *** in kidney transplant recipients is an underrecognized and poorly studied *** diseases are the leading cause of death among kidney transplant candidates with functioning *** contributes to the pathogenesis of many of the CV *** biomarkers and vasoreactivity tests are available to study endothelial *** an increasing number of transplants happening every year,and improved graft rejection rates due to the availability of effective immunosuppressants,the focus has now shifted to endothelial protection for the prevention,early recognition,and treatment of CV diseases.

关键词： Endothelial dysfunction Endothelium Cardiovascular disease Kidney transplantation Chronic kidney disease Nitric oxide Flow-mediated dilatation Nitro-glycerine-mediated dilatation Biomarkers

Impact of surgery for chronic pancreatitis on the risk of pancreatic cancer:Untying the Gordian knot

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World Journal of Gastroenterology 2021年第27期27卷 4371-4382页

作者： raja Kalayarasan Sankar narayanan Jayaprakash Sahoo Pazhanivel Mohan Department of Surgical Gastroenterology JIPMERPuducherry 605006India Department of Endocrinology JIPMERPuducherry 605006India Department of Medical Gastroenterology JIPMERPuducherry 605006India

Pancreatic ductal adenocarcinoma is an aggressive tumor with poor long-term *** pancreatitis(CP)is considered a risk factor for the development of pancreatic cancer(PC).Persistent pancreatic inflammation and activation of pancreatic stellate cells play a crucial role in the pathogenesis of CPrelated PC by activating the oncogene *** genetic mutations increase the possibility of recurrent and persistent pancreatic inflammation,they are not directly associated with the development of *** studies suggest that early surgical intervention for CP might have a protective role in the development of CP-related ***,the physician faces the clinical question of whether early surgical intervention should be recommended in patients with CP to prevent the development of ***,the varying relative risk of PC in different subsets of CP underlines the complex gene-environment interactions in the disease ***,it is essential to stratify the risk of PC in each individual *** review focuses on the complex relationship between CP and PC and the impact of surgical intervention on PC *** proposed risk stratification based on the genetic and environmental factors could guide future research and select patients for prophylactic surgery.

关键词： Chronic pancreatitis Pancreatic adenocarcinoma Pancreatic cancer Surgery Hereditary pancreatitis Pancreatitis

AN UNCONDITIONALLY STABLE HYBRID FE-FD SCHEME FOR SOLVING A 3-D HEAT TRANSPORT EQUATION IN A CYLINDRICAL THIN FILM WITH SUB-MICROSCALE THICKNESS

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Journal of Computational Mathematics 2003年第5期21卷 555-568页

作者： raja Nassar Mathematics and Statistics College of Engineering and Science Louisiana Tech University Ruston LA 71272 USA

Heat transport at the microscale is of vital importance in microtechnology applications. The heat transport equation is different from the traditional heat transport equation since a second order derivative of temperature with respect to time and a third-order mixed derivative of temperature with respect to space and time are introduced. In this study, we develop a hybrid finite element-finite difference (FE-FD) scheme with two levels in time for the three dimensional heat transport equation in a cylindrical thin film with sub-microscale thickness. It is shown that the scheme is unconditionally stable. The scheme is then employed to obtain the temperature rise in a sub-microscale cylindrical gold film. The method can be applied to obtain the temperature rise in any thin films with sub-microscale thickness, where the geometry in the planar direction is arbitrary.

关键词： Finite element Finite difference Stability Heat transport equation Thin film Microscale

Magnetic properties of gadolinium and/or dysprosium substituted Sm-Co nanocomposite ribbons

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Journal of Rare Earths 2024年第6期42卷 1093-1100,I0004页

作者： Akila raja Shampa Aich Department of Metallurgical A Materials EngineeringIndian Institute of Technology(IIT) Kharagpur721302India

The present study reported the influence of heavy rare-earth elements(Gd and/or Dy)on Sm-Co-based melt-spun *** and magnetic properties of Sm-Co-based(Sm_(1-x)RE_(x)Co_(5))ternary and quaternary systems were *** X-ray diffraction,Auger spectroscopy,scanning electron microscopy(SEM)and transmission electron microscopy(TEM)analyses reveal the presence of the 1:5H and 2:17R phases in the as-spun ribbons.A high-temperature magnetic measurement reports a Curie temperature(Tc)at~825 and~869 K in Sm0.6Gd0.4Co5(ribbon A)and Sm_(0.6)Gd_(0.3)Dy_(0.1)Co_(5)(ribbon B),respectively.A low-temperature magnetic measurement on Sm0.6Gd0.3Dy0.1Co5 ribbons exhibits a type-2 SR(spin reorientation)behaviour at~72 K,which arises due to the presence of the DyCo5 *** temperature magnetic measurements reveal that overall magnetic measurement(OMP)is about 24 and 29.9 for ribbons A and B,***,the comparative investigations profess that ribbon B shows better magnetic performance due to Dy addition with reduced grain *** observation indicates that the Gd and Dy substituted Sm-Co magnet can be a potential magnet for high-temperature applications.

关键词： Permanent magnets Melt-spinning Heavy rare-earth Curie temperature Rare earths

Frequency Analysis of Multiple Layered Cylindrical Shells under Lateral Pressure with Asymmetric Boundary Conditions

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Chinese Journal of Mechanical Engineering 2014年第1期27卷 23-31页

作者： ISVANDZIBAEI Mohammad Reza JAMALUDDIN Hishamuddin raja HAMZAH raja Ishak Faculty of Mechanical Engineering Universiti Teknologi Malaysia

Natural frequency characteristics of a thin-walled multiple layered cylindrical shell under lateral pressure are studied. The multiple layered cylindrical shell configuration is formed by three layers of isotropic material where the inner and outer layers are stainless steel and the middle layer is aluminum. The multiple layered shell equations with lateral pressure are established based on Love＇s shell theory. The governing equations of motion with lateral pressure are employed by using energy functional and applying the Ritz method. The boundary conditions represented by end conditions of the multiple layered cylindrical shell are simply supported-clamped（SS-C）, free-clamped（F-C） and simply supported-free（SS-F）. The influence of different lateral pressures, different thickness to radius ratios, different length to radius ratios and effect of the asymmetric boundary conditions on natural frequency characteristics are studied. It is shown that the lateral pressure has effect on the natural frequency of multiple layered cylindrical shell and causes the natural frequency to increase. The natural frequency of the developed multilayered cylindrical shell is validated by comparing with those in the literature. The proposed research provides an effective approach for vibration analysis shell structures subjected to lateral pressure with an energy method.

关键词： multiple layered ritz method lateral pressure shell boundary conditions

Unsupervised neural networks for solving Troesch＇s problem

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Chinese Physics B 2014年第1期23卷 546-556页

作者： Muhammad Asif Zahoor raja Department of Electrical Engineering COMSATS Institute of Information Technology Attock Campus Attock Pakistan

In this study, stochastic computational intelligence techniques are presented for the solution of Troesch's boundary value problem. The proposed stochastic solvers use the competency of a feed-forward artificial neural network for mathematical modeling of the problem in an unsupervised manner, whereas the learning of unknown parameters is made with local and global optimization methods as well as their combinations. Genetic algorithm (GA) and pattern search (PS) techniques are used as the global search methods and the interior point method (IPM) is used for an efficient local search. The combination of techniques like GA hybridized with IPM (GA-IPM) and PS hybridized with IPM (PS-IPM) are also applied to solve different forms of the equation. A comparison of the proposed results obtained from GA, PS, IPM, PS-IPM and GA-IPM has been made with the standard solutions including well known analytic techniques of the Adomian decomposition method, the variational iterational method and the homotopy perturbation method. The reliability and effectiveness of the proposed schemes, in term of accuracy and convergence, are evaluated from the results of statistical analysis based on sufficiently large independent runs.

关键词： Troesch’s problem artificial neural network genetic algorithm hybrid methods