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Epidemiological Aspects of Stillbirth and Neonatal Deaths in the Delivery Room at the Libreville Mother-Child University Hospital from 2019 to 2022

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Open Journal of Pediatrics 2024年第1期14卷 1-10页

作者： Eliane Kuissi Kamgaing Jacques Albert Bang Ntamack Opheelia Makoyo Komba Raïssa koumba maniaga Steeve Minto’o Rogombe Pascal Loulouga Badinga Aude Lembet Mikolo Simon Ategbo Department of Neonatal Medicine Jeanne Ebori Foundation Mother-Child University Hospital (JEFMCUH) of Libreville Libreville Gabon Department of Gynaecology and Obstetrics Jeanne Ebori Foundation (JEFMCUH) of Libreville Libreville Gabon Department of Paediatrics University of Health Sciences Libreville Gabon

Introduction: Stillbirths are estimated at 2 million each year, of which more than 40% occur during labour. Our objective was to study the epidemiological aspects of stillbirth and neonatal deaths in the delivery room in our health facility. Patients and methods: Prospective, descriptive and analytical study, conducted at the Jeanne Ebori Foundation Mother-Child University Hospital over 4 years (January 2019-December 2022). All neonatal deaths in the delivery room or foetal death in utero, were included. Results: Among the 18,346 deliveries performed, 512 newborns were declared dead in the delivery room (27.9‰ live births), divided into in utero foetal death (19.0‰) and immediate neonatal death (8.9‰). The mean age was 34.3 weeks of amenorrhea. The rate of preterm birth was 60.4%. The sex ratio was 1.1. The average weight was 2186.6. The main causes were vascular (46.1%), foetal (20.2%), adnexal (17.1%) and asphyxia per partum (16.6%). Foetal causes were more likely to result in IUFD than other causes (OR = 6.4 [2.4 - 15.7], p < 0.001). After birth, partum asphyxia was more likely to lead to death before 15 minutes of life than other causes (OR = 11 [6.1 - 18.9], p Conclusion: The causes of stillbirth and early neonatal mortality are dominated by maternal vascular pathologies. However, the proportion of childbirth-related causes remains worrying. Better monitoring of pregnancy and labour will minimize this prevalence in our hospital.

关键词： Stillbirth Neonatal Death Delivery Room Epidemiology Libreville-Gabon

Preliminary studies of acute and sub-chronic toxicity of the aqueous extract of Guibourtia tessmannii(Harms) *** stem barks (Caesalpiniaceae) in mice and rats

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Asian Pacific Journal of Tropical Biomedicine 2016年第6期6卷 506-510页

作者： Noreen Orianna koumba Madingou Aristide Traore Alain Souza Marlaine Michelle Boukandou Mounanga raissa Reine Aworet Samseny Sylvin Ouedraogo Alfred Sababenedyo Traore Laboratory of Pharmacology and Toxicology Pharmacopoeia and Traditional Medicines Institute Research Center in Biological Food and Nutritional SciencesUniversity of Ouagadougou Department of Medicine and Traditional Pharmacopoeia/Pharmacy Health Science Research Institute Department of Biology Faculty of SciencesUniversity of Sciences and Technique of Masuku(USTM)

Objective: To investigate the toxicity of aqueous extract of Guibourtia tessmannii(Harms) J. Leonard(G. tessmannii) and evaluate its ***: NMRI mice were used to determine the acute toxicity of G. *** concentrations of the plant extracts were administered intraperitoneally or by force-feeding. General behavior and death were monitored and recorded daily for 7 *** order to determine the sub-acute toxicity of the extract, several doses were administered by oral gavage daily for 28 days in adult Wistar rats. Different parameters were assessed including body weight, food and water intake, biochemical parameters and several vital organ ***: LD50 of 328.78 mg/kg was obtained by i.p. route and more than 5 000 mg/kg was obtained in acute toxicity by oral route. In sub-acute toxicity, no significant alteration was observed in body weight or vital organs, food and water intake, and biochemical ***: The results showed that the aqueous extract of G. tessmannii has low toxicity intraperitoneally and no sub-acute toxicity via oral intake.

关键词： Guibourtia tessmannii Stem barks Plant extract Herbal medicine Toxicity

Epidemiological Aspects of Stillbirth and Neonatal Deaths in the Delivery Room at the Libreville Mother-Child University Hospital from 2019 to 2022

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Management and Development of Newborns from Mothers Carrying HBsAg at the El Rapha Polyclinic in Libreville, Gabon

Open Journal of Pediatrics（儿科学期刊） 2024年第1期

作者： Eliane Kuissi Kamgaing Jacques Albert Bang Ntamack Opheelia Makoyo Komba Raïssa koumba maniaga Steeve Minto’o Rogombe Pascal Loulouga Badinga Aude Lembet Mikolo Simon Ategbo

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Open Journal of Pediatrics 2021年第3期11卷 468-478页

作者： Eliane Kuissi Kamgaing Steeve Minto’o Rogombe Aude-Mariella Lembet Mikolo Raïssa koumba maniaga Edmée Mintsa Mi Nkama Edgar-Brice Ngoungou Maiga Aité Blaise Okissi Marcelle Djiomo Simon Ategbo Polyclinique El Rapha Libreville Gabon Département de Pédiatrie Université des Sciences de la Santé (USS) Libreville Gabon Department of Biostatistics Université des Sciences de la Santé (USS) Libreville Gabon

Introduction: Hepatitis B is a significant public health problem. Infected children Objective: We aimed to assess newborns’ management and outcome from reactive HBs Ag mothers at the El Rapha Polyclinic in Libreville, Gabon. Methodology: Prospective longitudinal study, carried out over four years, including all neonates born from reactive HBsAg mothers admitted in the delivery room. The parameters studied were maternal age, gestation, marital status, pregnancy follow-up, hepatitis B vaccination status, knowledge of hepatitis B, anti-Hbc antibodies’ levels, HBeAg. For the newborn: term, birth weight, management at birth, and hepatitis B serological status at 12 months. Results: We included 45 newborns. Mothers’ mean age was 30.9 ± seven years. In 32.6% of cases, antenatal consultations were ≤4, and 9.3% were vaccinated for hepatitis B. Mothers had chronic hepatitis in 74.4% of cases. All neonates were vaccinated for hepatitis B at birth;68.9% received hepatitis B immunoglobulin. At 12 months, 77.8% had HBs antibody positive, and 6.7% were HBsAg positive. Conclusion: Hepatitis B prevalence is significant among parturients. It is essential to set up a national strategy for managing the mother-child couple in a context of positive HBsAg.

关键词： Viral Hepatitis B Newborn Management Evolution Gabon

Psychomotor Development of Low Birth Weight Infants at the “Mère-Enfant” University Hospital Centre (UHC) of Libreville

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Open Journal of Pediatrics 2023年第1期13卷 113-124页

作者： Kuissi Kamgaing Eliane Minto’o Rogombe Steeve Mintsa-Mi-Nkama Edmée Mabery Grodet Eyang Adriana Mino Lembet Mikolo Aude koumba maniaga Raïssa Kiba Live Boungani Morgane Loulouga Badinga Pascal Simon Ategbo Children’s Ward Neonatal Medicine Department University Hospital Centre “Mère-Enfant” Jeanne Ebori Foundation (UHCME-JEF) of Libreville Libreville Gabon Department of Pediatrics Faculty of Medicine UHS (University of Health Sciences) of Gabon Libreville Gabon

Introduction: Low birth weight is a key indicator of newborn health. The objective of this study was to contribute to the reduction of low birth weight-related morbidity and mortality. Patients and Methods: cohort study conducted from January 2019 to July 2020 at the “Mère-Enfant” University Hospital Centre (UHC) of Libreville. All newborns with a birth weight 2500 g were included. The clinical data of patients were studied. They were followed over a period of 12 months and assessed psychomotorly by the Brunet-Lézine scale. Results: 1260/9035 births of low birth weight (14.0%) were observed, and 300 among them were included. The mortality rate was 27.0% (81) and 219 were followed for 12 months. The sex ratio was 0.8, the average birth weight was 2008.6 ± 215.2 g. The average gestational age was 34 ± 12 weeks with 75.3% prematurity. An infant disease was observed in 61.6% of cases and respiratory pathologies were more observed except at 3 months of age where the proportion of digestive pathologies was 20.5%. At the time of the last consultation at 12 months of life, 76.2% of infants had no pathology. The quotients of postural development, language and coordination were normal (between 110 - 70) respectively in 75.4%, 99.1% and 68% of cases at the age of 12 months. The psychomotor development quotient was correlated with the birth weight in the language area r = 0.15 (p = 0.024), posture r = 0.15 (p = 0.015) and coordination r = 0.15 (p = 0.026) respectively. Conclusion: Low birth weight is a public health problem at UHCME-JEF. Despite the fact that psychomotor development can be said to be satisfactory, many efforts remain to be made to reduce low birth weight levels and improve survival.

关键词： Hypotrophy Psychomotor Development UHCME-JEF Libreville-Gabon

Psychomotor Development of Low Birth Weight Infants at the “Mère-Enfant”University Hospital Centre (UHC) of Libreville

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