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英国医学杂志中文版 2005年第4期8卷 235-238页

作者： Roger Shrimpton rainer gross Ian Darnton-Hill Mark Young 王燕飞 Centre for International Child Health Institute of Child HealthLondon WC1N 1EHhonorary senior research fellow Nutrition Section Programme DivisionUnicef New YorkUSAchief Nutrition Section Programme DivisionUnicef New YorkUSAsenior adviser micronutrients Health Section Programme DivisionUnicefsenior adviser

锌缺乏症在发展中国家很常见,有很高的死亡率在发展中国家,规律地补充锌可大大降低婴儿的发病率补锌还是一种有效治疗腹泻病的辅助方法锌缺乏症常与其他微量营养素缺乏症并存,包括铁缺乏症,因此补充一种营养素是不够的直到复合微量营养... 详细信息

锌缺乏症在发展中国家很常见,有很高的死亡率在发展中国家,规律地补充锌可大大降低婴儿的发病率补锌还是一种有效治疗腹泻病的辅助方法锌缺乏症常与其他微量营养素缺乏症并存,包括铁缺乏症,因此补充一种营养素是不够的直到复合微量营养素干预治疗的试验结果显示可行之后。

关键词：锌缺乏症干预措施微量营养素饮食多样化腹泻病

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The Mesenteric-Caval Fistula: First Results of a New Technique in a Transperitoneal Reconstruction of the Caval Vein by Fulminant Thrombosis of the Inferior Vena Cava Based on Homozygous Antithrombin III-Deficiency

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Surgical Science 2016年第8期7卷 342-347页

作者： Justus gross rainer Petzina Rouven Berndt Bernd Panholzer Andreas Bayer Katharina Huenges Leonie Aschauer Jochen Cremer Rene Rusch Department of Cardiac and Thoracic Vascular Surgery UKSH Kiel Germany

Recurrent thrombotic occlusions are one major problem in patients with thrombosis of the inferior vena cava. Due to this, we report a new surgical strategy for the construction of aorto-caval (mesenteric-caval) fistula in a patient with homozygous Antithrombin III (ATIII)-Deficiency. The patient survived postoperatively and only surgical complications grade I and II (Clavien-Dindo classification) were reported after short-term and one year follow-up. After one year, the CT-angiography did not show any caval thrombosis or stenosis and no restriction or occlusion of the fistula. Thus, the mesenteric-caval fistula could be safely performed and resulted in a satisfactory patency.

关键词： Mesenteric-Caval Fistula Thrombosis Transperitoneal Reconstruction Homozygous Antithrombin III-Deficiency

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Safety of fluralaner chewable tablets(Bravecto TM),a novel systemic antiparasitic drug,in dogs after oral administration

Safety of fluralaner chewable tablets(Bravecto TM),a novel s...

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中国畜牧兽医学会兽医药理毒理学分会第十五次学术讨论会

作者： Feli M Walther Mark J Allan rainer KA Roepke Martin C Nuernberger MSD Animal Health Innovation GmbH Zur Propstei

Background:Fluralaner is a novel systemic insecticide and acaricide that provides long acting efficacy in dogs after a single oral *** study investigated the safety oforal administration of fluralaner in chewable tablets to dogs at the highest recommended treatment dose and at multiples of this ***:Thirty-two(16 male and 16 female) healthy 8-week old Beagle dogs weighing 2.0-3.6 kg at first administration were included in the *** was administered on three occasions at 8-week intervals at doses of up to56,168,and 280 mg fluralaner/kg body weight,equivalent to 1,3,and 5 times the highest recommended treatment dose offluralaner;sham dosed dogs served as *** the study,all dogs were clinically observed,and their health was carefully monitored including body weightdevelopment,food consumption and measurement of hematology,coagulation,clinical chemistry(including measurement of levels of ACTH and C-reactive protein) and *** euthanasia of the dogs,complete gross post mortem examination,including organ weight determination,and histopathological examination of multiple tissues were ***:There were no clinical findings related to fluralaner *** significant differences between the treated groups and the control group were observed for some clinical pathology parameters and organ weights;none of these findings were considered to be of clinical ***:Oral administration of fluralaner at the highest recommended treatment dose(56 mg/kg) at 8-week intervals is well tolerated and has a safety margin of more than five in healthy dogs eight weeks of age or older and weighing at least 2 kg.

关键词： Fluralaner Dog Safety BravectoTM

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