检索结果-南通市图书馆

Health economic evaluation of moist wound care in chronic cutaneous leishmaniasis ulcers in Afghanistan

Infectious Diseases of Poverty 2018年第1期7卷 129-144页

作者： Hans-Christian Stahl Faridullah Ahmadi Sami Mohammad Nahzat Heng-Jin Dong Kurt-Wilhelm Stahl rainer sauerborn Institute of Public Health University Hospital HeidelbergHeidelbergGermany Malaria and Leishmaniasis Centre Provincial Civil Balkh HospitalMazar-e-SharifAfghanistan National Malaria and Leishmaniasis Control Program Ministry of Public HealthKabulAfghanistan Center for Health Policy Studies School of MedicineZhejiang UniversityHangzhouChina NGO Waisenmedizin e.V.–Promoting Access to Essential Medicine FreiburgGermany

Background:The present health economic evaluation in Afghanistan aims to support public health decision makers and health care managers to allocate resources efficiently to appropriate treatments for cutaneous leishmaniasis(CL)elicited by Leishmania tropica or Leishmania ***:A decision tree was used to analyse the cost and the effectiveness of two wound care regimens versus intra-lesional antimony in CL patients in *** were collected from a societal *** was measured in wound free *** incremental cost-effectiveness ratio(ICER)and incremental net monetary benefit(NMB)were *** model was parameterized with baseline parameters,sensitivity ranges,and parameter ***,the model was simulated and results were evaluated with deterministic and probability sensitivity *** outcomes were the efficiency of the regimens and a budget impact analysis in the context of ***:Average costs per patients were US$11(SE=0.016)(Group I:Intra-dermal Sodium Stibogluconate[IL SSG]),US$16(SE=7.58)(Group II:Electro-thermo-debridement[ETD]+Moist wound treatment[MWT])and US$25(SE=0.48)(Group III:MWT)in patients with a single chronic CL *** a societal perspective the budget impact analysis shows that the regimens’drug costs are lower than indirect disease *** effectiveness in wound free days are 177(SE=0.36)in Group II,147(SE=0.33)in Group III,and 129(SE=0.27)in Group *** ICER of Group II versus Group I was US$0.09 and Group III versus Group I US$0.77,which is very costeffective with a willingness-to-pay threshold of US$2 per wound free *** a Monte-Carlo probabilistic sensitivity analysis Group II was cost-effective in 80%of the cases starting at a willingness-to-pay of 80 cent per wound free ***:Group II provided the most cost-effective *** non-treatment alternative is not an option in the management of chronic CL *** of Group III should at le

关键词： Cutaneous leishmaniasis Wound healing Cost-effectiveness Sodium Stibogluconate Moist wound treatment

来源：