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隐匿型乙型肝炎病毒感染（下）

传染病网络动态 2007年第3期 16-18页

作者： Giovanni raimondo 董培玲（编译）杨月（审校）

HBV隐匿型感染的潜在临床相关性逐渐显现出来，而这正是这项研究升温的主要原因。隐匿型HBV感染可能影响四个不同的临床方面，下面我们详细讨论。

关键词：隐匿型感染乙型肝炎病毒感染临床相关性 HBV感染

Rare gastrointestinal lymphomas: the endoscopic investigation

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World Journal of Gastrointestinal Endoscopy 2015年第10期7卷 928-949页

作者： Calogero Vetro Giacomo Bonanno Giorgio Giulietti Alessandra Romano Concetta Conticello Annalisa Chiarenza Paolo Spina Francesco Coppolino Rosario Cunsolo Francesco Di raimondo Division of Hematology A.O."Policlinico-Vittorio Emanuele" University of Catania Division of Gastroenterology A.O."Polic-linico-Vittorio Emanuele" Department of Diagnostic and Interventional Radiology A.O."Policlinico-Vittorio Emanuele" Department of Radiology University of Palermo Health Direction A.O."Policlinico-Vittorio Emanuele"

Gastrointestinal lymphomas represent up to 10%of gastrointestinal malignancies and about one third of nonHodgkin *** most prominent histologies are mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell ***,the gastrointestinal tract can be the site of rarer lymphoma subtypes as a primary or secondary *** to their rarity and the multifaceted histology,an endoscopic classification has not been validated *** review aims to analyze the endoscopic presentation of rare gastrointestinal lymphomas from disease diagnosis to follow-up,according to the involved site and lymphoma ***,new and emerging endoscopic technologies have been *** particular,we investigated the diagnostic,prognostic and follow-up endoscopic features of T-cell and natural killer lymphomas,lymphomatous polyposis and mantle cell lymphoma,follicular lymphoma,plasma cell related disease,gastrointestinal lymphomas in immunodeficiency and Hodgkin’s lymphoma of the gastrointestinal *** to more frequent gastrointestinal lymphomas,data about rare lymphomas are mostly extracted from case series and case *** to the data paucity,a synergism between gastroenterologists and hematologists is required inorder to better manage the ***,clinical and prognostic features are different from nodal and extranodal or the bone marrow(in case of plasma cell disease)***,the approach should be based on the knowledge of the peculiar behavior and natural history of disease.

关键词： Endoscopy Lymphoma Endosonography Stomach Intestine

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隐匿型乙型肝炎病毒感染（上）

传染病网络动态 2007年第2期 13-15页

作者： Giovanni raimondo 董培玲（编译）杨月（审校）杨露绮（审校）

隐匿型乙肝病毒（HBV）感染的定义为乙肝表面抗原阴性的个体其肝组织中长期存在HBV基因组（有些病例血清中也可发现病毒基因组）。上世纪80年代早期开始发现这种HBV慢性感染的罕见形式后，人们从最初的怀疑到最近10年的较深认识得益于... 详细信息

隐匿型乙肝病毒（HBV）感染的定义为乙肝表面抗原阴性的个体其肝组织中长期存在HBV基因组（有些病例血清中也可发现病毒基因组）。上世纪80年代早期开始发现这种HBV慢性感染的罕见形式后，人们从最初的怀疑到最近10年的较深认识得益于高敏感度的分子生物学技术的应用。分子生物学技术的应用使人们能够揭示病毒学的各个方面、世界各地的分布情况及与临床表现可能存在的相关性。

关键词：乙型肝炎病毒感染隐匿型 HBV慢性感染分子生物学技术乙肝表面抗原阴性病毒基因组乙肝病毒临床表现

节奏趋同:西方当代舞蹈与东方搏击类运动的融合研究

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成都体育学院学报 2020年第4期46卷 121-126页

作者：塞尔吉奥·雷蒙多王永顺卡西诺和南拉齐奥大学人文社科学院意大利卡西诺03043 华侨大学体育学院福建厦门361021

著名的汉学家马塞尔·格拉内特指出,阴阳理论所传达的世界观概念是基于通用的节奏效率。此外,节奏这一概念也被认为是新科学范式的基础。近几十年,这些科学范式被用以讨论复杂理论,并旨在超越笛卡尔——牛顿简化论。舞蹈和搏击类运动是... 详细信息

著名的汉学家马塞尔·格拉内特指出,阴阳理论所传达的世界观概念是基于通用的节奏效率。此外,节奏这一概念也被认为是新科学范式的基础。近几十年,这些科学范式被用以讨论复杂理论,并旨在超越笛卡尔——牛顿简化论。舞蹈和搏击类运动是两种人类最常体验到的与整体节奏感有关的身体活动。近几十年来,西方当代舞蹈与东方搏击类运动之间的交流也越来越频繁。文章通过相关文献和图片分析东方搏击类运动和冥想技巧与西方古典和现代舞蹈之间的融合。西方当代舞蹈的不同趋势衍生出了四类表演,且从这四类表演中能明显看出其对亚洲搏击类运动的技巧、理念、走位与布景的借鉴。研究结果表明,文章中所分析的搏击类运动与舞蹈融合的案例体现出了表演、戏剧与仪式之间原始关系,这是古代社会象征的回归。美学享受保留了对象的真实感,同时在主观行动的影响下,创造出将人体合而为一的艺术体验。研究认为,亚洲搏击类运动是基于阴阳理论所展现的通用节奏效率,西方舞蹈重现了搏击类运动所包含的艺术成分,因而也再次寻求了这些搏击类运动哲学理念的基础:和谐,美好与宁静。

关键词：博击类运动舞蹈节奏效率肢体语言

Primary Embryonal Lung Carcinoma and Testicular Seminoma in the Same Patient Ten-Years Later: Case-Report and Literature Review

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Open Journal of Urology 2012年第2期2卷 83-86页

作者： Pasquale Rescigno Giuseppe Di Lorenzo Lucia raimondo Carmine D’Aniello Elide Matano Vincenzo Damiano Lucia Nappi Livio Puglia Antonella Petremolo Piera Federico Giovannella Palmieri Genitourinary Oncology and Rare Cancer Center Federico II University Naples Italy

Primary germ cell tumors of lung are extremely rare. The prognosis is usually poor, with various symptoms seriously affecting quality of life. In this paper we describe the unique case of a patient affected by an embryonal carcinoma of lung and a testicular seminoma after ten years. We also report literature about pulmonary extragonadal germ cell tumors.

关键词： Extragonadal Germ Cell Tumors Primary Pulmonary Germ Cell Tumor Embryonal Carcinoma Testicular Seminoma

运动振荡通气可能预测心力衰竭患者的心脏性猝死

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世界核心医学期刊文摘（心脏病学分册） 2007年第11期3卷 54-55页

作者： Guazzi M. raimondo R. Vicenzi M. 刘相飞 Cardiopulmonary Unit Cardiology Division University of Milano Milano Italy Dr.

目的:本研究旨在检测来自心肺运动试验(CPET)的各变量作为心脏性猝死(SCD)预测因素的价值。背景:CPET变量是慢性心力衰竭(CHF)患者全因死亡率的强预测因素,如峰值耗氧量(VO2)、通气需要量/CO2产量(VE/VCO2)斜率、运动振荡呼吸(EOB)。

关键词：性猝死 CPET SCD 泵衰竭预测因素患者心脏

对HBV和HCV合并感染的患者通过纵向评估揭示病毒学复合谱

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世界核心医学期刊文摘（胃肠病学分册） 2006年第10期2卷 49-50页

作者： raimondo G. Brunetto M.R. Pontisso P. 陈云茹 Unit of Clinical and Molecular Hepatology Department of Internal MedicinePoliclinico UniversitarioVia Consolare Valeria98124 MessinaItalyProf

Hepatitis B virus (HBV) and hepatitis C virus (HCV) coinfection is often associated with severe forms of liver disease. However, comprehensive studies are lacking, and scant information is available regarding the virological behavior over time in coinfected patients. This study enrolled 133 untreated HBV/ HCV-positive patients (male/female = 102/31; median age 51 years [range: 22-83 years]) who were longitudinally followed up for 1 year with bimonthly evaluation of HBV/HCV viremia levels and liver biochemistry. Thirty of these patients had triple infection with hepatitis Delta virus (HDV), while 103 patients were HDV-negative. In the HDV-negative group, active infection with both HBV and HCV was revealed in 24 cases, inactive infection by both viruses was seen in 15 cases, active HBV/ inactive HCV was seen in 15 cases, and inactive HBV/active HCV was seen in 49 cases. However, 32 subjects (31%) presented dynamic virological profiles characterized by fluctuation of HBV and/or HCV viremia levels that at different time points were over or under the cutoff limits. Consequently, a correct diagnosis could be performed in these subjects only by serially repeating the virological tests 1 year apart. Similarly, 15 of the 30 HDV-positive subjects showed active HBV and/or HCV infection, with fluctuating virological patterns in 8 cases. In conclusion, this study showed that the virological patterns in HBV/HCV coinfection are widely divergent and have dynamic profiles. A careful longitudinal evaluation of the viremia levels of both viruses is essential for making a correct diagnosis and tailoring the appropriate therapeutic schedule in coinfected patients.

关键词： HBV HCV 乙型肝炎病毒病毒血症非活动期丙型肝炎病毒肝脏疾病丁型肝炎综合性研究修正

准备接受肝移植的患者中胃窦血管扩张的发病率及自然病史

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世界核心医学期刊文摘（胃肠病学分册） 2005年第4期1卷 53-54页

作者： Ward E.M. raimondo M. Rosser B.G. 赵丽娜 Div. of Gastroenterol. and Hepatol. Mayo Clinic 4500 San Pablo Road Jacksonville FL 32224 United StatesDr.

Goals: To describe the prevalence and natural history of gastric antral vascular ectasia (GAVE) in patients with end-stage liver disease undergoing orthotopic liver transplantation (OLT). Background: GAVE is a well-recognized cause of gastrointestinal hemorrhage. Although 30%of patients with GAVE have liver disease, the prevalence of GAVE in patients with cirrhosis is not known. Study: We reviewed clinical records of patients who underwent OLT at our institution from February 1, 1998 to June 2003. Demographic and clinical details were recorded with attention to findings during upper endoscopy before and after OLT. Results: A total of 597 patients underwent OLT, and 345 were evaluated preoperatively with esophagogastroduodenoscopy (EGD). Eight (2.3%) were found to have GAVE before OLT. Three of these eight underwent EGD after OLT, and GAVE was absent in all three. None of the patients with GAVE experienced gastrointestinal bleeding postoperatively. Conclusions: GAVE was present in nearly 1 in 40 patients with end-stage liver disease who underwent EGD before OLT at our institution and appears to resolve after transplant. These findings are consistent with a previous report documenting resolution of GAVE after OLT.

关键词：肝移植自然病史血管扩张十二指肠镜消化道内镜检查临床记录胃镜检查人口统计学移植术临床资料

Serum SCCA-IgM as a predictor of hepatocellular carcinoma in patients with liver cirrhosis

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Open Journal of Gastroenterology 2012年第2期2卷 56-61页

作者： Daniela Buccione Gianluca Fatti Andrea Gallotta Elisabetta Loggi Roberto Di Donato Lilia Testa Carlo Saitta Valentina Santi Antonio Di Micoli Virginia Erroi Marta Frigerio Valentina Fazio Antonino Picciotto Alessandra Biasiolo Francoise Degos Patrizia Pontisso Giovanni raimondo Franco Trevisani APHP Hopital Beaujon INSERM U 773 Clichy France Dipartimento di Medicina Clinica e Sperimentale “G. Patrassi” Università di Padova Padova Italia Dipartimento di Medicina Clinica Alma Mater Studiorum-Università di Bologna Bologna Italia Dipartimento di Medicina Interna Policlinico Universitario di Messina Messina Italia Dipartimento di Medicina Interna Università di Genova Genova Italia Xeptagen S.p.A. Venezia Italia

Aberrant Squamous Cell Carcinoma Antigen (SCCA) expression is an early hepatocarcinogenetic event and circulating SCCA-IgM complexes are elevated in most HCC patients. We evaluated whether serum SCCA-IgM levels can identify HCV +ve cirrhotic patients at low HCC risk. In this retrospective study we enrolled 29 cirrhotic patients in whom serum SCCA-IgM was measured 8 - 69 months (median 31) before HCC diagnosis, and 28 cirrhotic patients who remained HCC- free, with SCCA-IgM measured 15 - 68 months (median 48) before the study end. The best discriminating value of SCCA-IgM was calculated and tested in predicting HCC diagnosis within 12, 24 and 36 months. Sensitivity analysis, considering different HCC incidence, was conducted to identify the patient subgroup with an annual cancer risk below the threshold of a cost-effective semiannual surveillance with ultrasound. Cumulative HCC incidence at 12, 24 and 36 months was 7.0%, 15.7% and 26.3%, respectively. SCCA-IgM levels were higher in HCC than in cirrhotic patients [median: 381 (95% C.I.: 50 - 5289) vs. 100 (70 - 493) AU/mL, P = 0.005]. The SCCA-IgM value ≤ 200 AU/mL accurately identified patients at low risk of HCC development in the subsequent year (sensitivity 75%, specificity 62%, positive predictive value 13% and negative predictive value 97%). Considering an annual HCC incidence ≤ 3%, patients with SCCA-IgM ≤ 200 AU/mL (60% of the whole patients) had an HCC risk below the accepted threshold of a cost-effective surveillance (1.5%). In conclusion, provided that our provocative results are confirmed in larger studies, SCCA-IgM serum measurement could permit implementation of a two step (with different costs) surveillance: an initial serological surveillance, based on the annual monitoring of this biomarker, and the conventional surveillance by semiannual US when SCCA-IgM becomes >200 AU/mL. This could improve the cost/effectiveness of surveillance of HCV infected patients at risk of HCC.

关键词： SCCA-IgM HCC Risk Assessment Surveillance Cost/Effectiveness