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Journal of Traditional Chinese Medicine 2022年第3期42卷 426-431页

作者： Mushtaq Ahmed Naila Sher Nadia Mushtaq rahmat ali khan Department of Biotechnology Faculty of Biological SciencesUniversity of Science&TechnologyBannu 28100KPK-Pakistan Department of Botany Faculty of Biological SciencesUniversity of Science&TechnologyBannu 28100KPKPakistan

OBJECTIVES:To estimate the existence of phytochemicals and then to determine the antidiabetic activity againstα-amylase andβ-glucosidase inhibition in ***:The study was carried out by following standard ***:Phytochemicals analysis indicated the presence of different *** total phenolic content was 6.055 mg GAE/g and the total flavonoid content was 5.706 mg RU/g in the plant *** total saponins,alkaloids,and tannins contents were(0.044%),(2.88%)and(2.862 nm)respectively.α-amylase inhibition activity of Calligonum polygonoides(CP)extract was 70%with IC50 of 610μg/mL and that ofβ-glucosidase inhibition activity was 65%with IC50 of 640μg/***:The findings reported for the first time the antidiabetes-promoting effects of an extract of CP in vitro,thus validating their promising anti-diabetes potential.

关键词： Calligonum polygonoides phytochemicals alpha-amylases beta-glucosidase

THREE POINT BOUNDARY VALUE PROBLEMS FOR NONLINEAR FRACTIONAL DIFFERENTIAL EQUATIONS

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Acta Mathematica Scientia 2011年第4期31卷 1337-1346页

作者： Mujeeb ur Rehman rahmat ali khan Naseer Ahmad Asif National University of Sciences and Technology (NUST) Centre for Advanced Mathematics and Physics University of Malakand Chakdara Dir(L) Khyber Pakhtunkhawa Pakistan

In this paper, we study existence and uniqueness of solutions to nonlinear three point boundary value problems for fractional differential equation of the type c D δ 0＋ u（t） = f （t, u（t）, c D σ 0＋ u（t））, t ∈ [0, T ], u（0） = αu（η）, u（T ） = βu（η）, where 1 〈 δ 〈 2, 0 〈 σ 〈 1, α, β∈ R, η∈ （0, T ）, αη（1 -β）＋（1-α）（T βη） = 0 and c D δ 0＋ , c D σ 0＋ are the Caputo fractional derivatives. We use Schauder fixed point theorem and contraction mapping principle to obtain existence and uniqueness results. Examples are also included to show the applicability of our results.

关键词： fractional differential equations three point boundary conditions existence and uniqueness results

Pistacia chinensis:Strong antioxidant and potent testicular toxicity amelioration agent

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Asian Pacific Journal of Tropical Medicine 2017年第4期10卷 359-369页

作者： Farah Noureen Muhammad Rashid khan Naseer ali Shah rahmat ali khan Kiran Naz Saadia Sattar Department of Biochemistry Faculty of Biological SciencesQuaid-i-Azam University Department of Biosciences COMSATS Institute of Information Technology Department of Biotechnology UST Bannu KPK

Objective:To evaluate in ritro and in riro antioxidant potency of Pistacia chinensis(***) bark and leaves extracts along with its protective role against CCl_4 induced toxicity in testis of the *** Various in vitro models such as DPPH,ABTS,hydrogen peroxide,superoxide,hydroxyl and nitric oxide scavenging activities,anti-lipid peroxidation activity,phospho-molybdenum activity.β carotene bleaching assay was used for analysis of antioxidant *** groups for in riro study were:Group Ⅰ(control)*** Ⅱ(Vehicle control).Group Ⅲ(1 mL/kg b.w 30%CCl_4).Group Ⅳ(1 mL/kg b.w CCk_4+Silymarin).Group Ⅴ(200 mg/kg b.w PCBE+CCl_4),Group Ⅵ(400 mg/kg b.w PCBE+CCl_4) and Group Ⅶ(400 mg/kg b.w PCBE alone).Results:In ritro antioxidant assays displayed significant results and the highest activity was not specified to a specific ***,ethyl acetate extract of bark(PCBF) showed highest results in most of the antioxidant assays ***-carotene bleaching,hydroxyl radical *** peroxidation and superoxide radical scavenging *** this base,this fraction was selected for in riro antioxidant *** tissues were analyzed to observe the protective effects of PCBE on antioxidant enzymes:cataluse,superoxide *** reductase,glutathione peroxidase and quinone reductase activities and glutathione(GSH) as well as nitrite *** of plasma testosterone was also compared to various *** suggests a protective role of *** against CCl_4induced ***:It is concluded that some bioactive antioxidants of *** bark might be a good source to isolate the potent antioxidant components.

关键词： Pislacia chinensis Plasma testosterone Glutathione-S-transferase Antioxidant enzymes

Efficacy of Silene arenosa extract on acetylcholinesterase in Bungarus sindanus(krait) venom

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Journal of Traditional Chinese Medicine 2021年第3期41卷 349-354页

作者： Adil Shah Mushtaq Ahmed Naila Sher Nadia Mushtaq rahmat ali khan Fozia Midrarullah Department of Biotechnology Faculty of Biological SciencesUniversity of Science&TechnologyBannu 28100KPK-Pakistan Department of Botany Faculty of Biological SciencesUniversity of Science&TechnologyBannu 28100KPK-Pakistan Department of Biochemistry KMU Institute of Medical SciencesKohat 26000Pakistan Department of Biotechnology Saheed Benazir Bhutto UniversitySheringalDir UpperKPK-Pakistan

OBJECTIVE:To examine the efficacy of Silene arenosa extract on acetylcholinesterase (AChE) of krait (Bungarus Sindanus) snake ***:The present project designed to evaluate the inhibition of AChE by following standard ***:Statistical analysis of the results showed that Silene arenosa exerted 73%inhibition against the krait venom acetylcholinesterase at fixed substrate acetylcholine (ACh) concentration (0.5 mM).Kinetic analysis using the Lineweaver Burk plot revealed that Silene arenosa caused a competitive type of inhibition i.e.K_(m) values increased from 26.6 to 93.3 mM (26.6%to 93.3%) and V_(max)remained constant in a concentration-dependent *** arenosa competes with the substrate to bind at the active site of the *** K_(mapp)of venom AChE for Silene arenosa increased from 60%to 81.6%and the V_(maxapp)remains constant.K_(i)(inhibition constant was estimated to be 48μg for snake venom);while the K_(m)(Michaelis-Menten constant of AChE-substrate into AChE and product) was estimated to be 0.5 *** IC_(50)of AchE calculated for Silene arenosa was 67μ***:The present results suggest that Silene arenosa extract can be considered as an inhibitor of snake venom AChE.

关键词： acetylcholinesterase snake venoms silene arenosa competitive inhibition

A Synergistic Multi-Attribute Decision-Making Method for Educational Institutions Evaluation Using Similarity Measures of Possibility Pythagorean Fuzzy Hypersoft Sets

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 501-530页

作者： Khuram ali khan Saba Mubeen Ishfaq Atiqe Ur Rahman Salwa El-Morsy Department of Mathematics University of SargodhaSargodha40100Pakistan Department of Mathematics University of Management and TechnologyLahore54000Pakistan Department of Mathematics College of ScienceQassim UniversityBuraydah51452Saudi Arabia

Due to the numerous variables to take into account as well as the inherent ambiguity and uncertainty,evaluating educational institutions can be *** concept of a possibility Pythagorean fuzzy hypersoft set(pPyFHSS)is more flexible in this regard than other theoretical fuzzy set-like models,even though some attempts have been made in the literature to address such *** study investigates the elementary notions of pPyFHSS including its set-theoretic operations union,intersection,complement,OR-and *** results related to these operations are also modified for ***,the similarity measures between pPyFHSSs are formulated with the assistance of numerical examples and ***,an intelligent decision-assisted mechanism is developed with the proposal of a robust algorithm based on similarity measures for solving multi-attribute decision-making(MADM)problems.A case study that helps the decision-makers assess the best educational institution is discussed to validate the suggested *** algorithmic results are compared with the most pertinent model to evaluate the adaptability of pPyFHSS,as it generalizes the classical possibility fuzzy set-like theoretical ***,while considering significant evaluating factors,the flexibility of pPyFHSS is observed through structural comparison.

关键词： Hypersoft set Pythagorean fuzzy hypersoft set computational complexity multi-attribute decision-making optimization similarity measures uncertainty

Ultrasonic vibration-assisted cutting of titanium alloys:A state-of-the-art review

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Chinese Journal of Aeronautics 2025年第1期38卷 3-42页

作者： Ahmar khan Xin WANG Biao ZHAO Wenfeng DING Muhammad JAMIL Aqib Mashood khan Syed Hammad ali Sadam HUSSAIN Jiong ZHANG Raj DAS National Key Laboratory of Science and Technology on Helicopter Transmission Nanjing University of Aeronautics and AstronauticsNanjing 210016China Department of Mechanical Engineering College of EngineeringCity University of Hong KongHong Kong 999077China Centre for Additive Manufacturing School of EngineeringAerospace Engineering and AviationRMIT UniversityVictoria 3083Australia

The remarkable ability of titanium alloys to preserve their superior physical and chemical characteristics when subjected to extreme conditions significantly enhances their importance in the aerospace,military,and medical ***,conventional machining of titanium alloys leads to elevated tool wear,development of surface defects,and reduced machining efficiency due to their low heat conductivity,and chemical *** issues can be somewhat counteracted by integrating ultrasonic vibration in the conventional machining of titanium alloys and also enhance *** review article offers a holistic evaluation of the influence of ultrasonic vibration-assisted milling and turning on cutting forces,temperature,tool wear,and surface integrity,encompassing surface morphology,surface roughness,surface residual stress,surface hardness,and surface tribological properties during titanium alloys ***,it investigates the sustainability aspect that has not been previously *** on the performance of ultrasonic-assisted cutting revealed several advantages,including decreased cutting forces and cutting temperature,improved tool life,and a better-machined surface during ***,the sustainability factor is improved due to minimized energy consumption and residual *** conclusion,the key challenges and future prospects in the ultrasonic-assisted cutting of titanium alloys are also *** review article provides beneficial knowledge for manufactur-ers and researchers regarding ultrasonic vibration-assisted cutting of titanium alloy and will play an important role in achieving sustainability in the industry.

关键词： Ultrasonic vibration-assisted cutting Titanium alloys Material removal mechanism Machinability Sustainability

Recent developments in MQL machining of aeronautical materials:A comparative review

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Chinese Journal of Aeronautics 2025年第1期38卷 43-69页

作者： Syed Hammad ali Yu YAO Bangfu WU Biao ZHAO Wenfeng DING Muhammad JAMIL Ahmar khan Asra BAIG Qi LIU Dongdong XU National Key Laboratory of Science and Technology on Helicopter Transmission Nanjing University of Aeronautics and AstronauticsNanjing 210016China Department of Mechanical Engineering NED University of Engineering and TechnologyKarachi 75270Pakistan Centre for Precision Manufacturing University of StrathclydeGlasgow G11XQUK School of Mechanical Engineering Tongji UniversityShanghai 200092China

Minimum quantity lubrication(MQL),as a new sustainable and eco-friendly alternative cooling/lubrication technology that addresses the limitations of dry and wet machining,utilizes a small amount of lubricant or coolant to reduce friction,tool wear,and heat during cutting *** technique has witnessed significant developments in recent years,such as combining MQL with other sustainable techniques to achieve optimum results,using biodegradable lubricants,and innovations in nozzle designs and delivery *** review presents an in-depth analysis of machining characteristics(e.g.,cutting forces,temperature,tool wear,chip morphology and surface integrity,etc.)and sustainability characteristics(e.g.,energy consumption,carbon emissions,processing time,machining cost,etc.)of conventional MQL and hybrid MQL techniques like cryogenic MQL,Ranque-Hilsch vortex tube MQL,nanofluids MQL,hybrid nanofluid MQL and ultrasonic vibration assisted MQL in machining of aeronautical ***,the latest research and developments are analyzed and summarized in the field of MQL,and provide a detailed comparison between each technique,considering advantages,challenges,and limitations in practical *** addition,this review serves as a valuable source for researchers and engineers to optimize machining processes while minimizing environmental impact and operational ***,the potential future aspects of MQL for research and industrial execution are discussed.

关键词： Aerospace materials Minimum Quantity Lubrication(MQL) Cryogenic Nanofluid Grinding Milling Sustainability

Deep Learning and Artificial Intelligence-Driven Advanced Methods for Acute Lymphoblastic Leukemia Identification and Classification: A Systematic Review

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Computer Modeling in Engineering & Sciences 2025年第2期142卷 1199-1231页

作者： Syed Ijaz Ur Rahman Naveed Abbas Sikandar ali Muhammad Salman Ahmed Alkhayat Jawad khan Dildar Hussain Yeong Hyeon Gu Department of Computer Science Islamia CollegePeshawar25120Pakistan Department of Information Technology The University of HaripurHaripur22620Pakistan College of Technical Engineering The Islamic UniversityNajaf100986Iraq School of Computing Gachon UniversitySeongnam13120Republic of Korea Department of AI and Data Science Sejong UniversitySeoul05006Republic of Korea

Automatic detection of Leukemia or blood cancer is one of the most challenging tasks that need to be addressed in the healthcare *** of white blood cells(WBCs)in the blood or bone marrow microscopic slide images play a crucial part in early identification to facilitate medical *** Acute Lymphocytic Leukemia(ALL),the most preferred part of the blood or marrow is to be analyzed by the experts before it spreads in the whole body and the condition becomes *** researchers have done a lot of work in this field,to demonstrate a comprehensive analysis few literature reviews have been published focusing on various artificial intelligence-based techniques like machine and deep learning detection of *** systematic review has been done in this article under the PRISMA guidelines which presents the most recent advancements in this *** image segmentation techniques were broadly studied and categorized from various online databases like Google Scholar,Science Direct,and PubMed as image processing-based,traditional machine and deep learning-based,and advanced deep learning-based models were *** Neural Networks(CNN)based on traditional models and then the recent advancements in CNN used for the classification of ALL into its subtypes.A critical analysis of the existing methods is provided to offer clarity on the current state of the ***,the paper concludes with insights and suggestions for future research,aiming to guide new researchers in the development of advanced automated systems for detecting life-threatening diseases.

关键词： Acute lymphoblastic bone marrow segmentation classification machine learning deep learning convolutional neural network

Analysis of transverse momentum spectra of protons,deuterons,and tritons in symmetric heavy-ion collisions at√S_(NN)=200 GeV at the RHIC

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Chinese Physics C 2025年第1期49卷 223-237页

作者： Waqas Ahmad Ihsan Ullah ali Zaman Imran khan Akhtar Iqbal Abdul Qudus Sana Ullah Naseeb Ullah Muhammad Ramzan Department of Physics University of Science and TechnologyBannuKP28100 Pakistan Department of Physics COMSATS University IslamabadIslamabadPakistan Department of Physics The University of Lakki MarwatLakki MarwatKhyber PukhtunkhwaPakistan Department of Physics Govt.Degree CollegeSarai NaorangKhyber PukhtunkhwaPakistan

The blast wave model with Tsallis statistics is used to analyze the transverse momentum spectra of protons(p),deuterons(d),and tritons(t)in√S_(NN)=200 GeV gold-gold(Au-Au)collisions at the RHIC in various centrality *** particular transverse momentum ranges,the model results closely match experimental data from the PHENIX(p)and STAR(d and t)*** data are compared with those of protons obtained in Cu+Cu collisions and deuterons and tritons in Ru+Ru collisions at a center of mass energy of 200 GeV from the STAR *** spectra are used to derive the kinetic freeze-out temperatures,transverse flow velocities,and freeze-out *** to the findings,the kinetic freeze-out temperature increases from the central to peripheral *** this transition,the transverse flow velocity and freeze-out volume both *** the collisions of both collaborations,this study reveals mass-dependent kinetic freeze-out temperature and differential volume ***,the non-extensivity parameter q decreases with increasing centrality of the studied heavy-ion collisions,and heavier mass particles have smaller values of q,which implies higher degrees of thermalization and equilibrium in more central collisions and for heavier particles.

关键词： transverse momentum temperature Au+Au Cu+Cu freeze-out STAR collisions LHC Pb+Pb

Dielectric characteristic of dichlorodifluoromethane(R12)gas and mixture with N_(2)/air as an alternative to SF_(6)gas

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High Voltage 2017年第3期2卷 205-210页

作者： rahmat Ullah Abdur Rashid Arooj Rashid Faisal khan Amjad ali Department of Electrical Engineering CIIT AbbottabadPakistan

In this study,dichlorodifluoromethane(R12)gas and mixtures with nitrogen(N_(2))and air at different pressures and mixing ratios have been investigated and showed good alternative to SF_(6) gas in terms of high-voltage *** gases contain R12 gas,they offer good dielectric properties and possibility to be used in low-temperature *** effects and self-recoverability test have been *** strength under quasi-uniform field showed in the order of SF_(6)>R12>N_(2)>air in alternating current(AC),direct current(DC)and impulse was *** R12/N_(2)(80/20%)could reach over 0.90–0.95 times to that of SF_(6) gas at 50 lb/in^(2) at AC and R12/air(70/30%)gives 0.80–0.90 to SF_(6) gas.R12 gas presents brilliant *** optimal ratio to switch SF_(6) gas is R12/N_(2)(80/20%)and R12/air(70/30%)is based on the authors’experimental condition and setup.

关键词： characteristic mixture mixing