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Evaluation of the 8th AJCC staging system for pathologically versus clinically staged pancreatic adenocarcinoma: A time to revisit a dogma?

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Hepatobiliary & Pancreatic Diseases International 2018年第1期17卷 64-69页

作者： Omar Abdel-rahman Clinical Oncology Department Faculty of Medicine Ain Shams University

Background: The 8 th edition of the American Joint Committee on Cancer(AJCC) staging system for pancreatic exocrine adenocarcinoma has been released. The current study seeks to assess the 7 th and 8 th editions among patients registered within the surveillance, epidemiology and end results(SEER) ***: SEER database(2010–2013) has been accessed through SEER*Stat program and AJCC 8 th edition stages were reconstructed utilizing the collaborative stage descriptions. Kaplan–Meier analysis of overall survival and pancreatic cancer-specific survival analyses(according to both 7 th and 8 th editions and according to whether pathological or clinical staging were conducted) has been performed. Multivariate analysis of factors affecting pancreatic cancer-specific survival was also conducted through a Cox proportional hazard ***: A total of 18 948 patients with pancreatic adenocarcinoma were identified in the period from 2010–2013. Pancreatic cancer-specific survival among pathologically staged patients and according to the 8 th edition showed significant differences for all pair wise comparisons among different stages(P < 0.0001) except for the comparison between stage IA and stage IB(P = 0.307) and the comparison between stage IB and stage IIA(P = 0.116). Moreover, P value for stage IA vs IIA was 0.014; while pancreatic cancer-specific survival according to the 7 th edition among pathologically staged patients showed significant differences for all pair wise comparisons among different stages(P < 0.0001) except for the comparison between IA and IB(P = 0.072), the comparison between stage IIA and stage IIB(P = 0.065), the comparison between stage IIA and stage Ⅲ(P = 0.059) and the comparison between IIB and Ⅲ(P = 0.595).Among clinically staged patients(i.e. those who did not undergo initial radical surgery), the prognostic performance of both 7 th and 8 th stages for both overall survival and pancreatic cancer-specific survival was ***: Th

关键词： Pancreatic cancer AJCC SEER Prognosis

Sensitivity analysis of the DehumReq model to evaluate the impact of predominant factors on dehumidification requirement of greenhouses in cold regions

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Information Processing in Agriculture 2023年第2期10卷 216-228页

作者： Md Sazan rahman Huiqing Guo Department of Mechanical Engineering University of Saskatchewan57 Campus driveSaskatoonSK S7N 5A9Canada Department of Bioresource Engineering McGill UniversityMacdonald Stewart Building21111 Lakeshore RoadSainte-Anne-de-BellevueQC H9X 3V9Canada

In this study,the sensitivity of a novel dehumidification requirement model(DehumReq)is analyzed to evaluate the effect of the predominant factors on the dehumidification needs of the *** hourly dehumidification demand and sensitivity coefficient(SC)are estimated for three different seasons:warm(July),mild(May),and cold(November),by using the local sensitivity analysis *** on SC values,the solar radiation,air exchange,leaf area index(LAI),and indoor setpoints(temperature,relative humidity(RH),and water vapor partial pressure(WVPP))have significant impact on the dehumidifi-cation needs,and the impact varies from season to *** parameters have a higher SC in summer,whereas solar radiation and LAI have a higher SC in mild *** dehumidification load increases 4 times of its base value with increasing solar radiation by 200 W/m^(2),and the highest LAI(10)caused 5 times increment of the *** changing of WVPP from its base value(1.5 kPa)to maximum(2.9 kPa)reduces the load 70%in *** exchange was found to be the most crucial parameter because it is the main dehumidification approach that has a large range and is easily adjustable for any *** air exchange by ventilation or infiltration will reduce the dehumidification load to zero in May and November and minimizes it to only nighttime load in *** the other parameters,higher ambient air RH and indoor air speed will result in higher the dehumidification load;whereas higher inner surface condensation will result in lower dehumidifi-cation *** result of this study will assist in the selection of the most efficient moisture control strategies and techniques for greenhouse humidity control.

关键词： Greenhouse Dehumidification DehumReq model Sensitivity analysis Solar radiation Air exchange

Large scale of identification of differentially expressed genes in the regenerating rat liver after SISPH

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Science China(Life Sciences) 2005年第6期48卷 624-635页

作者： rahman Salman Homophilia Research Center London University London SE17EH United Kingdom

Extensive gene expression analysis was carried out after a 0, 4, 36, 72, 96 h short interval successive partial hepatectomy (SISPH) was performed. A total of 185 elements were identified as differing by more than two-fold in their expression levels at one or more time points. Of these 185 elements, 103 were up-regulated, 82 were down-regulated and 86 elements were unreported genes. Quite a few genes were previously unknown to be involved in liver regenera-tion (LR). Using cluster and general analysis, we found that the genes at five time points of the SISPH share eight different types of different expression profiles and eight distinct temporal in-duction or suppression patterns. A comparison of the gene expression in SISPH with that after PH found that 41 genes were specifically altered in SISPH, and 144 genes were simultaneously up-regulated or down-regulated in SISPH and after PH, but they were present in different amounts at the different time points. The conclusions are that (i) microarrays combined with suppressive subtractive hybridization (SSH) can effectively identify genes involved in LR on a large scale; (ii) more genes were up-regulated than down-regulated; (iii) there are fewer abun-dantly expressed genes than those with increased levels of 2-5 fold.

关键词： partial hepatectomy (PH), short interval successive partial hepatectomy (SISPH), liver regeneration (LR), subtracted cDNA libraries, complementary DNA microarray, cluster analysis.

Impact of industrial effluent on growth and yield of rice(Oryza sativa L.) in silty clay loam soil

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Journal of Environmental Sciences 2015年第4期27卷 231-240页

作者： Mohammad Anwar Hossain Golum Kibria Muhammad Mustafizur rahman Mohammad Mizanur rahman Abul Hossain Molla Mohammad Mostafizur rahman Mohammad Khabir Uddin Department of Environmental Sciences Jahangirnagar University Department of Soil Science Bangabandhu Sheikh Mujibur Rahman Agricultural University Department of Bioenvironmental Science Bangabandhu Sheikh Mujibur Rahman Agricultural University

Degradation of soil and water from discharge of untreated industrial effluent is alarming in Bangladesh. Therefore, buildup of heavy metals in soil from contaminated effluent, their entry into the food chain and effects on rice yield were quantified in a pot experiment. The treatments were comprised of 0, 25%, 50%, 75% and 100% industrial effluents applied as irrigation water. Effluents, initial soil, different parts of rice plants and post-harvest pot soil were analyzed for various elements, including heavy metals. Application of elevated levels of effluent contributed to increased heavy metals in pot soils and rice roots due to translocation effects, which were transferred to rice straw and grain. The results indicated that heavy metal toxicity may develop in soil because of contaminated effluent *** metals are not biodegradable, rather they accumulate in soils, and transfer of these metals from effluent to soil and plant cells was found to reduce the growth and development of rice plants and thereby contributed to lower yield. Moreover, a higher concentration of effluent caused heavy metal toxicity as well as reduction of growth and yield of rice, and in the long run a more aggravated situation may threaten human lives,which emphasizes the obligatory adoption of effluent treatment before its release to the environment, and regular monitoring by government agencies needs to be ensured.

关键词： Biomass Crop yield Heavy metal Industrial effluent Soil pollution

Bayesian Optimized LightGBM model for predicting the fundamental vibrational period of masonry infilled RC frames

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Frontiers of Structural and Civil Engineering 2024年第7期18卷 1084-1102页

作者： Taimur rahman Pengfei ZHENG Shamima SULTANA Department of Civil Engineering World University of BangladeshDhaka 1230Bangladesh School of Civil Engineering Zhengzhou UniversityZhengzhou 450001China Department of Computer Science&Engineering University of Asia PacificDhaka 1205Bangladesh

The precise prediction of the fundamental vibrational period for reinforced concrete(RC)buildings with infilled walls is essential for structural design,especially earthquake-resistant *** learning models from previous studies,while boasting commendable accuracy in predicting the fundamental period,exhibit vulnerabilities due to lengthy training times and inherent dependence on pre-trained models,especially when engaging with continually evolving data *** predicament emphasizes the necessity for a model that adeptly balances predictive accuracy with robust adaptability and swift data *** latter should include consistent re-training ability as demanded by realtime,continuously updated data *** research implements an optimized Light Gradient Boosting Machine(LightGBM)model,highlighting its augmented predictive capabilities,realized through the astute use of Bayesian Optimization for hyperparameter tuning on the FP4026 research data set,and illuminating its adaptability and efficiency in predictive *** results show that the R^(2) score of LightGBM model is 0.9995 and RMSE is 0.0178,while training speed is 23.2 times faster than that offered by XGBoost and 45.5 times faster than for Gradient ***,this study introduces a practical application through a streamlit-powered,web-based dashboard,enabling engineers to effortlessly utilize and augment the model,contributing data and ensuring precise fundamental period predictions,effectively bridging scholarly research and practical applications.

关键词： masonry-infilled RC frame fundamental period LightGBM FP4026 research dataset machine learning data-driven approach Bayesian Optimization

Development of a protocol for frost-tolerance evaluation in rapeseed/canola(Brassica napus L.)

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The Crop Journal 2016年第2期4卷 147-152页

作者： Danielle Fiebelkorn Mukhlesur rahman Department of Plant Sciences North Dakota State University

Spring frost can severely damage or even kill rapeseed/canola(Brassica napus L.) seedlings. A protocol for large scale screening of rapeseed germplasm under frost-simulating conditions has not yet been developed. Accordingly, the present study was conducted to develop a protocol for screening rapeseed germplasm under artificial frost-simulation conditions in a plant growth chamber and in a greenhouse. Nine rapeseed varieties, including three commercial hybrids, three spring types, and three winter types were used. Cold acclimation at 4 °C was applied for 0, 7, or 14 days to two-week old seedlings. The seedlings were treated with four freezing temperatures(- 4 °C,- 8 °C,- 12 °C, and- 16 °C). The length of the freezing period was 16 h, including the ramping of temperature down from 4 °C and up from the respective freezing temperature to 4 °C. Plants were allowed to recover at 4 °C for24 h before they were moved back to the greenhouse. Frost damage was scored on a 0–5scale, where 0 denotes completely dead and 5 denotes no damage. Seedling survival from the freezing treatment increased from the non-acclimation to the cold acclimation treatment. However, no significant differences(P < 0.05) were found between 7 and14 days of acclimation. Frost treatment at- 4 °C resulted in significant differences in seedling damage relative to the other three temperatures, with the- 16 °C treatment resulting in the highest overall seedling damage. Significant differences were found between the spring type and the other two types(hybrid and winter). However, no significant differences were found between the hybrid and winter types. The suggested protocol for the assessment of frost tolerance is acclimation of two-week old seedlings for7 days at 4 °C followed by frost treatment at- 4 °C for 16 h.

关键词： Frost tolerance Controlled environment Brassica napus Seedling

An Optimized CNN Model Architecture for Detecting Coronavirus (COVID-19) with X-Ray Images

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Computer Systems Science & Engineering 2022年第1期40卷 375-388页

作者： Anas Basalamah Shadikur rahman Umm Al-Qura University MakkahSaudi Arabia Daffodil International University DhakaBangladesh

This paper demonstrates empirical research on using convolutional neural networks(CNN)of deep learning techniques to classify X-rays of COVID-19 patients versus normal patients by feature *** extraction is one of the most significant phases for classifying medical X-rays radiography that requires inclusive domain *** this study,CNN architectures such as VGG-16,VGG-19,RestNet50,RestNet18 are compared,and an optimized model for feature extraction in X-ray images from various domains invol-ving several classes is *** X-ray radiography classifier with TensorFlow GPU is created executing CNN architectures and our proposed optimized model for classifying COVID-19(Negative or Positive).Then,2,134 X-rays of normal patients and COVID-19 patients generated by an existing open-source online dataset were labeled to train the optimized *** those,the optimized model architecture classifier technique achieves higher accuracy(0.97)than four other models,specifically VGG-16,VGG-19,RestNet18,and RestNet50(0.96,0.72,0.91,and 0.93,respectively).Therefore,this study will enable radiol-ogists to more efficiently and effectively classify a patient’s coronavirus disease.

关键词： X-ray image classification X-ray feature extraction COVID-19 coronavirus disease convolutional neural networks optimized model

Description of the biology of Caspian vimba,Vimba vimba(Linnaeus,1758),in Gorgan Bay-Miankaleh Wildlife Refuge(southeast Caspian Sea)

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Chinese Journal of Oceanology and Limnology 2010年第6期28卷 1173-1179页

作者： PATIMAR rahman SAFARI Sajjad Gonbad Institutes of Higher Education

We collected Vimba vimba throughout the spawning season （mid April to mid June, 2007） in Gorgan Bay （south-western Iran） and investigated its age, growth, and reproductive traits. The maximum age was 5＋ years. Both sexes grew allometrically （positive for males： b=3.140 9 and negative for females： b=2.791 4）. The von Bertalanffy growth functions were described by the formulae Lf=32.565（1-e-0.184（t＋0.530）） for males and Lt=35.950（1-e-0.179（t＋0.529）） for females. The overall sex ratio was balanced, but males were predominant in the smaller size classes and females in the larger size classes. Based on the gonadosomatic index （GSI） values, spawning appears to occur between late April and late May in the bay. The highest mean GSI was 6.44 for males in early May and 20.36 for females in late April Absolute fecundity varies from the minimum of 5 436 eggs for age 3＋ fish to the maximum of 36 141 eggs for age 5＋ fish. Fecundity was also positively correlated with fish size （length and weight）. Egg diameter ranged from 1.05 to 1.70 nun in the mean of 1.42 mm. There was no correlation between female size and ova diameter.

关键词： ~mba vimba age growth reproduction Gorgan Bay Iran

Zinc Oxide Nano Particles Integrated Kenaf/Unsaturated Polyester BioComposite

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Journal of Renewable Materials 2019年第10期7卷 967-982页

作者： Mohammed Mohammed Bashir O.Betar Rozyanty rahman Aeshah M.Mohammed Azlin F.Osman Muhammed Jaafar Tijjani Adam Omar S.Dahham Uda hashim Nik Z.Noriman Center of Excellence Geopolymer and Green Technology School of Materials EngineeringUniversiti Malaysia PerlisKangarPerlisMalaysia Research Center(NANOCAT) University of MalayaKuala LumpurMalaysia College of Health Solutions.Health North Building Arizona State UniversityArizonaUSA College of Education for Pure Science Ibn-Alhaitham University of BagdadBagdadIraq Faculty of Engineering Technology Universiti Malaysia PerlisKampus Uniciti Alam Sg.ChuchuhPadang Besar(U)PerlisMalaysia Institute of Nano Electronic Engineering Universiti Malaysia PerlisKangarPerlisMalaysia.

Increasing need for materials with special features have brought various new inventions,one of the most promising hope for new material with special features and functionalities is composites ***,this study report an integration of zinc nanoparticles into kenaf/polyester polymer composite to introduce new behavior to the *** composite behaviors were compared for mechanical,thermal,moisture absorption and biodegradability *** Zinc Oxide nanoparticles entrenched in the kenaf/polyestaer composites net structure through chemical bonds between kenaf/ZnO/polyester resin,existence of ZnO significantly influence the mechanical and thermals properties of *** analysis based on(TGA)response revealed the integration of ZnO nanoparticles improved the thermal stability when thermal decomposition temperature beyond 3650 *** thermal cracking decreased with present of ZnO and increase with kenaf content(layers).The modulus,Tensile strength,break at elongation,flexural modulus,flexural strength and impact strength of the composites with higher content kenaf/ZnO nanoparticle are 560 MPa,58MPa,1.8%,1300 PMa,68 MPa and 31 MPa,***,addition of kenaf layers and ZnO results in larger mechanical properties enhancement,the results of the contact angle show improvement in wetting of the fibres with addition of ZnO nanoparticles.

关键词： Polymer composite thermal properties mechanical properties nano-composite biodegradable polymer nano zinc oxide