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Diagnostic performance of C-reactive protein level and its role as a potential biomarker of severe dengue in adults

Asian Pacific Journal of Tropical Medicine 2020年第8期13卷 358-365页

作者： raghavendra rao Snehal Nayak Akhilesh K Pandey Shobha U Kamath Department of Medicine Kasturba Medical CollegeManipalIndia Manipal Academy of Higher Education ManipalIndia Department of Biochemistry Kasturba Medical CollegeManipalIndia Department of Community Medicine Kasturba Medical CollegeManipalIndia

Objective: To determine the relationship between C-reactive protein(CRP) level and the severity of dengue and the potential use of CRP in predicting acute dengue ***: A prospective observational study was performed on dengue patients admitted to a tertiary care hospital in southern India. All patients of age above 18 years, diagnosed with dengue were included in the study. The detailed laboratory parameters pertaining to dengue were recorded. CRP levels were estimated and compared between groups i.e. severe and non-severe dengue. CRP cut-off value was detected using the receiver-operator ***: Totally 98 patients with a mean age of 40 years were included. Among them, 11.2% of the patients suffered from severe dengue, 54.1% of the cases had non-severe dengue without warning signs, and 34.7% had non-severe dengue with warning signs. The median CRP was significantly higher in patients with severe dengue compared to patients with non-severe dengue(96.2 mg/d L vs. 5.3 mg/d L). Univariate logistic regression analysis showed that the odd’s ratio(OR) of CRP was 1.053(P≤0.001, 95% CI=1.029-1.078). CRP at a cutoff value of 21.6 mg/L(0.929 AUC) had excellent sensitivity(100%) and specificity(81.6%) in predicting severe dengue infection. Multivariate logistic regression analysis showed that CRP(OR=1.089, P=0.013) and ALT(OR=1.010, P=0.034) were statistically significant independent predictors of dengue ***: CRP level could be used as a potential biomarker to predict severity of dengue in adults.

关键词： Vector-borne Arbovirus Inflammation Biochemical Tropical disease

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Dielectric dispersion,linear and nonlinear optical properties of Li_(2)O-WO_(3)-B_(2)O_(3):V_(2)O_(5)glasses

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Journal of Advanced Dielectrics 2020年第3期10卷 64-71页

作者： Linganaboina Srinivasa rao Chinthakuntla Thirmal Parchuri raghavendra rao Centre for Nanoscience and Technology Department of Physics(Humanities&Sciences)VNR Vignana Jyothi Institute of Engineering and Technology Bachupally Nizampet(S.O)Hyderabad-500090TelanganaIndia Department of Physics Malla Reddy Engineering College for Women Maisamma Guda Dhulapally(PO)Secundrabad-500100TelanganaIndia

40 Li_(2)O–5WO_(3)–(55-x)B_(2)O_(3):xV_(2)O_(5)(mol%)for 0.0≤x≤0.8 glasses were prepared by *** polarization was described in terms of the dielectric constant("0)and loss(tanδ).Mixed conduction phenomenon was explained by redox pairs V^(4+)↔V^(5+)and W^(5+)↔W^(6+) at high *** polarizability(αe)was determined over a range of frequencies(100 Hz–100 kHz)and temperatures(30–280℃).The change of boron coordination in the glass network was explained with the aid of temperature coefficient of polarizability(φ).Nonlinear susceptibility(χ^((3)))and optical band gap(E°)were studied as a function of concentration of V_(2)O_(5).The highest values ofαe andχ^((3))were obtained at x=0.6 mol%.These glasses may find potential practical applications in the fields of solid-state ionics and nonlinear optics.

关键词： Dielectric properties electronic polarizability third-order nonlinear optical susceptibility optical band gap

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Experimental studies of water hammer in propellant feed system of reaction control system

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Propulsion and Power Research 2018年第1期7卷 52-59页

作者： Avanish Kumar P.Satya Prasad M.raghavendra rao Defence Research&Development Laboratory HyderabadTelangana 500058India

Water hammer pressure transient produces large dynamic forces which can damage the pipes and other assemblies in the feed line of a reaction control system(RCS).It has led to the failure of pressure transducers monitoring the manifold pressure in the feed line of ***,water hammer studies have been carried out to understand its effect in feed *** system has been simplified to develop a mathematical model and experiments have been carried out at extensive *** mathematical model was developed considering pipe of uniform c/s and moving liquid-gas *** experimental studies have been done using water as working medium instead of actual *** studies showed that rate of pressurization have a very critical role on the water hammer *** studies have been also carried out to study the effect of density,friction and initial liquid column length on water hammer amplitude.

关键词： Water hammer Reaction control system(RCS) Propellant feed system Experimental study Testing

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Long-term effects of management systems on crop yield and soil physical properties of semi-arid tropics of Vertisols

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Agricultural Sciences 2011年第4期2卷 435-442页

作者： Prabhakar Pathak Suhas P Wani raghavendra rao Sudi 不详

Long-term experiments can be used to assess management induced changes in soil properties and sustainability of the management system in terms of the productivity. Such data are scanty, especially in the semi-arid tropics (SAT) region. A long-term experiment established in 1976 at ICRISAT in India on Vertisols with two management treatments;improved management (IM), comprising semi-permanent broadbed and furrow (BBF) landform with minimum tillage and improved cropping practices;and traditional management (TM) system comprising keeping the land fallow during the rainy season and sowing on flat landform during post-rainy season with traditional cropping practices, was sampled after 24 and 34 years for soil physical and hydrological properties. Results showed that both in short-and long-term the management systems had profound effect on crop yields. Also in the long-term IM and TM management systems had significant effect on several soil physical and hydrological properties. Throughout the soil profile IM systems had significantly lower bulk density, significantly higher porosity, substantially lower penetration resistance both at 5 cm (1 and 8 MPa) and 15 cm depths (8 and 15 MPa), significantly higher infiltration and sorptivity and significantly larger mean weight diameter of 4.3 mm compared to 2.8 mm for soils under TM. However, management systems had no significant effect on moisture holding capacities both at 0.033 and 1.5 MPa. Significant differences between the improved and traditional systems were observed in the size and pattern of soil surface cracks. Over the long-term, the improved management systems has very favorable effects on soil physical and hydrological properties and on the soil surface cracking and its patterns, thereby contributing to higher productivity.

关键词： Broadbed and Furrow System Minimum Tillage Long-Term Experiment Sustainability

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Long-term effects of management systems on crop yield and soil physical properties of semi-arid tropics of Vertisols

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Agricultural Sciences 2011年第4期

作者： Prabhakar Pathak Suhas P Wani raghavendra rao Sudi

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Prospective Analysis of Patients Treated with Chemotherapy in Metastatic Adenocarcinoma of Lung—Single Centre Experience

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Journal of Cancer Therapy 2017年第9期8卷 838-844页

作者： B. J. Srinivasa L. P. Bhanu Girish Badarke Mohammad Nasiruddin Sulav Sapkota D. Tousif Vishal Kulkarni P. K. Kiran Vinu Sarathy G. S. Deepika Amritanshu Ram raghavendra rao Shekar Patil Radheshyam Naik Department of Medical Oncology HCG SC Bangalore India

Background: Lung cancer is the leading cause of cancer-related death worldwide with an estimated 1.6 million new cases diagnosed each year. According to standard guidelines in NSCLC, the effectiveness of combined chemotherapy regimen comprises of pemetrexed and platinum, and very few reports are available in Indian population. This study shows the experience with pemetrexed and platinum combination chemotherapy in metastatic NSCLC in first line setting. Methods: Total 61 patients with following inclusion criteria were recruited such as: 1) PS of 1 and 2;2) NSCLC of non-squamous histology;3) locally advanced or metastatic disease at diagnosis;4) should have received minimum 3 cycles of pemetrexed and platinum as first line treatment and or continued for 6 cycles;5) EGFR/ALK mutated or EGFR/ALK unknown patients but must have received upfront chemo. Primary endpoint of the present study is to assess Disease Control Rate (DCR) (CR + PR + SD). Progression Free Survival, OS and Toxicity assessment were secondary endpoints. Results: The mean number of average chemotherapy cycles was found to be 4.38. The range of chemotherapy was 2 - 6 cycles. Disease control rate, defined as (CR + PR + SD), was seen in 44 (72.1%) patients. (PR in 26 (42.62%), SD 18 (29.5%)), Progressive disease (PD) was observed in 17 (27.9%) patients. Overall study showed that patients had PFS of 9.414 months (95% CI 6.709 - 12.120) and OS of 13.437 months (95% CI 10.721 - 16.153). Conclusion: Pemetrexed and platinum combination is effective and well-tolerated chemotherapy regimen in patients with metastatic adenocarcinoma lung cancer patients. Pemetrexed and cisplatin may be more effective in particular. Early switch over to TKIs is preferred immediately after obtaining molecular subtype result.

关键词： Pemetrexed Carboplatin NSCLC Cisplatin EGFR

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Magnesium alloys as extremely promising alternatives for temporary orthopedic implants-A review

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Journal of Magnesium and Alloys 2023年第8期11卷 2688-2718页

作者： C.A.Niranjan T.raghavendra Madhuri P.rao C.Siddaraju M.Gupta Vikram Kumar S.Jain R.Aishwarya Department of Industrial Engineering and Management Ramaiah Institute of TechnologyBengaluru-54India Department of Mechanical Engineering National Institute of EngineeringMysuru-08India Department of Chemistry B.M.S.College of EngineeringBengaluru-19India Department of Mechanical Engineering Ramaiah Institute of TechnologyBengaluru-54India Department of Mechanical Engineering NUS Singapore-75Singapore Department of Metallurgical and Materials Engineering Indian Institute of TechnologyMadras-36India

Mg alloys are emerging as potential and very promising alternatives for replacing permanent metallic implant materials such as steels and titanium in applications where the implants need to be removed following healing through revision *** of Mg alloys for implant application is seen as a game changer and Mg alloys are almost perfect materials for the future in both engineering and biomedical *** review therefore focuses on highlighting significance of Mg alloys in biomedical field and risks of using permanent metallic implants particularly when the implants are no longer required after the injury is *** this review,importance of orthopedic implants in present scenario,serious concern related to accidents that are causing permanent disabilities,demand in orthopedic implant market worldwide,potential applications of Mg based materials and their compatibility in biological environment is presented and *** addition,degradation rate,major reactions associated with Mg based materials and effect of alloying elements on implant performance are also discussed based on in-vivo *** advances in development of Mg alloys through various techniques and their performance in in-vitro conditions are also *** ways to eliminate the limitations of Mg alloys include alloying,melt purification,surface alterations,surface modifications,chemical treatment,secondary processing *** *** and opportunities for Mg alloys to become ideal implant material is also addressed.

关键词： Accidents Fractures Burden of fracture Magnesium Ultimate alternative Degradation rate Alloying Melt purification Coating

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Multimodal Biometric Score Fusion Using Gaussian Mixture Model and Monte Carlo Method

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Journal of Computer Science & Technology 2010年第4期25卷 771-782页

作者： R raghavendra rao Ashok G Hemantha Kumar Department of Studies in Computer Science University of Mysore Department of E&C Channabasaveshwara Institute of Technology

Multimodal biometric fusion is gaining more attention among researchers in recent days. As multimodal biometric system consolidates the information from multiple biometric sources, the effective fusion of information obtained at score level is a challenging task. In this paper, we propose a framework for optimal fusion of match scores based on Gaussian Mixture Mode] （GMM） and Monte Carlo sampling based hypothesis testing. The proposed fusion approach has the ability to handle： 1） small size of match scores as is more commonly encountered in biometric fusion, and 2） arbitrary distribution of match scores which is more pronounced when discrete scores and multimodal features are present. The proposed fusion scheme is compared with well established schemes such as Likelihood Ratio （LR） method and weighted SUM rule. Extensive experiments carried out on five different multimodal biometric databases indicate that the proposed fusion scheme achieves higher performance as compared with other contemporary state of art fusion techniques.

关键词： multimodal biometric system match score level fusion Gaussian mixture model Monte Carlo method.

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枳和枳杂种对脚腐病抗性的评价

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中国南方果树 1985年第3期 40-40页

作者： N.N.raghavendra rao,沈兆敏印度

本试验采用实生苗根系接种的方法,测定了10个枳品系和6个枳杂种对脚腐病(供试病原为phytophthora nicotianae *** Haan ***(Dast.)Waterh)抗性的差异,以期筛选出最抗病或最耐病的品系。供试的枳品系是:鲁比杜克斯枳、Srirampur枳、Ponce... 详细信息

本试验采用实生苗根系接种的方法,测定了10个枳品系和6个枳杂种对脚腐病(供试病原为phytophthora nicotianae *** Haan ***(Dast.)Waterh)抗性的差异,以期筛选出最抗病或最耐病的品系。供试的枳品系是:鲁比杜克斯枳、Srirampur枳、Ponceroy枳、Rich枳、Chethalli枳、Towne枳、Pomeroy枳、大花枳、Christensen枳;枳杂种是:Srirampur特洛亚枳橙、施文格枳柚、Srirampur

关键词：脚腐病吸收根主根病斑文格抗性评价杂种杂交种

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Mango internal defect detection based on optimal wavelength selection method using NIR spectroscopy

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Artificial Intelligence in Agriculture 2021年第1期5卷 43-51页

作者： Anitha raghavendra D.S.Guru Mahesh K.rao Maharaja Research Foundation Maharaja Institute of TechnologyMysoreIndia Department of Studies in Computer Science University of MysoreMysoreIndia

A non-destructive technique should be developed for performance analysis of mango fruits because the spongy tissue or internal defects could lower the quality of mango fruit and incur a lack of *** this study,wavelength selection methods were proposed to identify the range of wavelengths for the classification of defected and healthy mango *** selection methods were adopted here to achieve a significant selection of *** measure the goodness of themodel,the datasetwas collected using the NIR(Near Infrared)spectroscopy with wavelength ranging from 673 nm–1900 *** classification was performed using Euclidean distance measure both in the original feature space and in FLD(Fisher's Linear Discriminant)transformed *** experimental results showed that the lower range wavelength(673 nm–1100 nm)was the efficient wavelength for the detection of internal defects in *** to express the effectiveness of the model,different feature selection techniques were investigated and found that the Fisher's criterion based technique appeared to be the best method for effective wavelength selection useful for classification of defected and healthy mango *** optimal wavelengths were found in the range of 702.72 nm to 752.34 nm using Fisher's criterionwith a classification accuracy of 84.5%.This study showed that NIR systemis a useful technology for the automaticmango fruit assessmentwhich has the potential to be used for internal defects in online sorting,easily distinguishable by those who do not meet minimum quality requirements.

关键词： Feature selection methods Fisher's linear discriminant analysis Mango internal defect detection NIR(near infrared spectroscopy)

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