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D-Dimer: Predictor of Postpartum Hemorrhage amon. Pre-Eclampsia at Kiliman.aro Christian.Medical Cen.re

Open.Journ.l of Obstetrics an. Gyn.cology 2024年第6期14卷 923-937页

作者： Husn. Silim Ally n.asatu G. Chamba Raziya Gaffur n.sra Batchu Glory Man.i Pen.o S. Mlay Bariki Mchome Mtoro J. Mtoro Thomas J. Kakumbi rafiki n. mjema Doris Rwen.agila Eusebius Maro Fredrick Mbise Gilleard Masen.a Patricia S. Swai Departmen. of Obstetrics an. Gyn.ecology KCMC Hospital Moshi Tanzania Departmen. of Obstetrics an. Gyn.ecology Kilimanjaro Christian Medical University College (KCMUCo) Moshi Tanzania

Backgroun.: Postpartum hemorrhage (PPH) is the major con.ributor to matern.l mortality an. morbidity worldwide as well as in.Tan.an.a. Studies have shown.Pre-eclampsia as a risk in.icator for Postpartum hemorrhage an. D-dimer ten.s to rise in.women.with pre-eclampsia. Few studies that have shown.the association.between.D-dimer an. PPH have been.con.roversial an. differ accordin. to ethn.city an. lifestyle. Hen.e there is n. suitable referen.e in.erval for D-dimer in.predictin. Postpartum hemorrhage amon. women.with pre-eclampsia. Broad Objective: This study aimed to assess the association. sen.itivity, an. specificity of D-dimer as a laboratory predictor of postpartum hemorrhage amon. women.with pre-eclampsia at KCMC hospital. Methodology: This was a hospital-based an.lytical cross-section.l study con.ucted at KCMC Hospital in.n.rthern.Tan.an.a from September 2022 to March 2023. A total of 195 women.with pre-eclampsia were in.luded in.this study. Plasma D-dimer levels were taken.from women.with pre-eclampsia pre-delivery. Haematocrit was compared before an. after delivery, an. a fall of 10% was con.idered as Postpartum hemorrhage together with clin.cal assessmen. of the patien.. Participan.s were divided amon. those who had severe features an. those who did n.t have severe features an. were further categorized in.o those who had PPH an. those who did n.t have PPH. Logistic regression.was used to determin. the association.between.D-dimer an. PPH adjustin. for other factors. The Receiver Operatin. Curve (ROC) was used to evaluate the predictive value. Results: Higher median.D-dimer levels were seen.amon. women.who had PPH compared to those who had n. PPH. D-dimer was seen.to be associated with PPH, thus for every un.t in.rease of µg/ml of D-dimer amon. women.who had pre-eclampsia without severe features there was a 14% sign.fican. in.rease in.the odds of havin. postpartum hemorrhage an. a 45% sign.fican. in.rease of havin. postpartum hemorrhage amon. those who had pre

关键词： D-Dimer Preeclampsia Postpartum Hemorrhage Tan.an.a

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