检索结果-南通市图书馆

Microanalysis of supersaturated gas release based on wall-attached bubbles

在线全文

学校读者我要写书评

暂无评论

Water science and Engineering 2021年第1期14卷 80-86页

作者： Lu Lin Ran Li Jing-jie Feng Ying-han huang Xiao-dong Yong yang-ming ou You-quan Yuan state Key Laboratory of Hydraulics and Mountain River Engineering Sichuan UniversityChengdu 610065China Power China Zhongnan Engineering Corporation Limited Changsha 410014China sichuan Qingyuan Engineering Consulting Co. Ltd.Chengdu 610072China College of Architecture and Civil Engineering Chengdu UniversityChengdu 610106China

supersaturation of dissolved gases in natural water,due to spillage from high dams and other factors,may cause fish *** previous experiments,the dissipation coefficient has been used to denote the degassing process of total dissolved gas(TDG)*** experiments mainly analyzed supersaturated TDG dissipation from a macroscopic *** precisely clarify the mechanism of supersaturated TDG release,this study investigated bubble adsorption at a wall surface from a microscopic *** experiment was conducted in a Plexiglas-wall container filled with supersaturated TDG water.A model that calculates the adsorption flux of supersaturated TDG by a solid wall,and helps describe construction for a contact angle at a three-phase intersection,was developed according to Young's *** model was used to investigate the formation process of bubbles adsorbed on a solid polymethyl methacrylate(PMMA)surface in supersaturated TDG *** adsorption effect of a solid wall on TDG release was analyzed based on the experimental *** modeling results were compared with observations under different wall area conditions,and it was found that TDG release tended to increase with wall *** study helps improve our understanding of the mechanisms of supersaturated TDG release and provides an important theoretical method for accurate calculation of the release *** adsorption flux model of the solid wall provides mitigation measures to combat the adverse effects of TDG supersaturation,which will be beneficial to the protection of aquatic organisms in hydropower-regulated rivers.

关键词： supersaturation Total dissolved gas Wall-attached bubbles Release Calculation model

Antibiotics De-Escalation in the Treatment of Ventilator-Associated Pneumonia in Trauma Patients： A Retrospective study on Propensity score Matching Method

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2018年第10期131卷 1151-1157页

作者： Hu Li Chun-Hui yang Li-ou huang Yu-Hui Cui Dan Xu Chun-Rong Wu Jian-Guo Tang Department of Critical Care Medicine Shanghai Fifth People's Hospital Fudan University Shanghai 200240 China

Background： Antimicrobial de-escalation refers to starting the antimicrobial treatment with broad-spectrum antibiotics, followed by narrowing the drug spectrum according to culture results. The present study evaluated the effect of de-escalation on ventilator-associated pneumonia （VAP） in trauma patients. Methods： This retrospective study was conducted on trauma patients with VAP, who received de-escalation therapy （de-escalation group） or non-de-escalation therapy （non-de-escalation group）. Propensity score matching method was used to balance the baseline characteristics between both groups. The 28-day mortality, length of hospitalization and Intensive Care Unit stay, and expense of antibiotics and hospitalization between both groups were compared. Multivariable analysis explored the factors that influenced the 28-day mortality and implementation of de-escalation. Results： Among the 156 patients, 62 patients received de-escalation therapy and 94 patients received non-de-escalation therapy. No significant difference was observed in 28-day mortality between both groups （28.6% vs. 23.8%, P = 0.620）. The duration of antibiotics treatment in the de-escalation group was shorter than that in the non-de-escalation group （11 [8-13] vs. 14 [8-19] days, P = 0.045）. The expenses of antibiotics and hospitalization in de-escalation group were significantly lower than that in the non-de-escalation group （6430 ± 2730 vs. 7618 ± 2568 RMB Yuan, P = 0.043 and 19,173 ± 16,861 vs. 24,184 ± 12,039 RMB Yuan, P = 0.024, respectively）. Multivariate analysis showed that high Acute Physiology and Chronic Health Evaluation Ⅱ （APACHE Ⅱ） score, high injury severity score, multi-drug resistant （MDR） infection, and inappropriate initial antibiotics were associated with patients＇ 28-day mortality, while high APACHEⅡ score, MDR infection and inappropriate initial antibiotics were independent factors that prevented the implementation of de-escalation. Conclusions： De-escalation strategy in the treat

关键词： De-Escalation Propensity score Matching Trauma Ventilator-Associated Pneumonia

在线全文

学校读者我要写书评

暂无评论

基于变蒸学说论小儿自闭症

河南中医 2024年第5期44卷 676-680页

作者：区舜尧郑铎雯黄嘉伟陈滢映徐小英王鹏丽钱国强广东药科大学广东广州510006

变蒸异常是导致小儿自闭症的主要因素,主要病机为心气不足、心窍不通、肝气郁结及脾肾不足等,临床表现为精神、意识、思维、活动等异常。变蒸异常会导致患儿神乱出现性情急躁、易怒多动、目不视人、目光回避等症状,且这些病症常与脾肾... 详细信息

变蒸异常是导致小儿自闭症的主要因素,主要病机为心气不足、心窍不通、肝气郁结及脾肾不足等,临床表现为精神、意识、思维、活动等异常。变蒸异常会导致患儿神乱出现性情急躁、易怒多动、目不视人、目光回避等症状,且这些病症常与脾肾功能的先天、后天异常以及肠道菌群紊乱等密切相关。临证治疗变蒸异常应在注意儿童情志畅达的同时,采用益精填髓、醒脑开窍的方法保证儿童之变蒸正常,且脑髓的充养对小儿自闭症的发展与转归也尤为重要,在开通玄府的同时,也要注意脑髓的充养,以防止病情反复。

关键词：变蒸学说小儿自闭症发热肠道菌群紊乱

High-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA

在线全文

学校读者我要写书评

暂无评论

signal Transduction and Targeted Therapy 2023年第9期8卷 4320-4337页

作者： Zhi-Wei Mo Yue-Ming Peng Yi-Xin Zhang Yan Li Bi-Ang Kang Ya-Ting Chen Le Li Mary Gsorci-Thomas Yi-Jun Lin yang Cao si Chen Ze-Long Liu Jian-Jun Gao Zhan-Peng huang Jia-Guo Zhou Mian Wang Guang-Qi Chang Meng-Jie Deng Yu-Jia Liu Zhen-sheng Ma Zuo-Jun Hu Yu-Gang Dong Zhi-Jun ou Jing-song ou Division of Cardiac surgery Cardiovascular Diseases InstituteThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina National-Guangdong Joint Engineering Laboratory for Diagnosis and Treatment of Vascular Diseases NHC Key Laboratory of Assisted Circulation(Sun Yat-sen University)Guangdong Provincial Engineering and Technology Center for Diagnosis and Treatment of Vascular DiseasesGuangzhouChina Division of Vascular surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Division of Hypertension and Vascular Diseases Department of CardiologyHeart CenterThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Medical College of Wisconsin MilwaukeeWIUSA Center for Translational Medicine Institute of Precision MedicineThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Department of Cardiology Heart CenterThe First Affiliated HospitalSun Yat-sen UniversityGuangzhouChina Department of Pharmacology Cardiac and Cerebral Vascular Research CenterZhongshan School of Medicine of Sun Yat-sen UniversityGuangzhouChina Guangdong Provincial Key Laboratory of Brain Function and Disease Zhongshan School of MedicineSun Yat-sen UniversityGuangzhou 510080P.R.China

Normal high-density lipoprotein(nHDL)can induce angiogenesis in healthy ***,HDL from patients with coronary artery disease undergoes various modifications,becomes dysfunctional(dHDL),and loses its ability to promote ***,we identified a long non-coding RNA,HDRACA,that is involved in the regulation of angiogenesis by *** this study,we showed that nHDL downregulates the expression of HDRACA in endothelial cells by activating WW domain-containing E3 ubiquitin protein ligase 2,which catalyzes the ubiquitination and subsequent degradation of its transcription factor,Kruppel-like factor 5,via sphingosine 1-phosphate(s1P)receptor *** contrast,dHDL with lower levels of s1P than nHDL were much less effective in decreasing the expression of *** was able to bind to Ras-interacting protein 1(RAIN)to hinder the interaction between RAIN and vigilin,which led to an increase in the binding between the vigilin protein and proliferating cell nuclear antigen(PCNA)mRNA,resulting in a decrease in the expression of PCNA and inhibition of *** expression of human HDRACA in a hindlimb ischemia mouse model inhibited the recovery of *** together,these findings suggest that HDRACA is involved in the HDL regulation of angiogenesis,which nHDL inhibits the expression of HDRACA to induce angiogenesis,and that dHDL is much less effective in inhibiting HDRACA expression,which provides an explanation for the decreased ability of dHDL to stimulate angiogenesis.

关键词： angiogenesis lipoprotein inhibited

肝移植术后胆道并发症的发生与高水平纤维蛋白(原)降解产物的相关性分析

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

实用器官移植电子杂志 2024年第3期12卷 215-219页

作者：潘比黄译贤欧晏娇张城城刘炜刘兴超张雷达陆军军医大学第一附属医院西南医院肝胆外科重庆400038 四川省医学科学院·四川省人民医院肝胆外科四川成都610000

目的研究纤维蛋白(原)降解产物(fibrin degradation product,FDP)水平与肝移植术后胆道并发症(biliary complications,BC)发生之间的潜在关系,总结BC发生的相关危险因素。方法回顾性分析2015年1月—2022年7月陆军军医大学第一附属医院... 详细信息

目的研究纤维蛋白(原)降解产物(fibrin degradation product,FDP)水平与肝移植术后胆道并发症(biliary complications,BC)发生之间的潜在关系,总结BC发生的相关危险因素。方法回顾性分析2015年1月—2022年7月陆军军医大学第一附属医院和四川省人民医院491例肝移植的人口统计学资料、临床指标和预后随访信息。采用重叠加权(overlap weighting,OW)平衡各组患者中的混杂因素。利用接受者操作特性(receiver operating characteristic,ROC)曲线来确定FDP的最佳临界值。Logistic回归模型分析影响预后的危险因素。结果491例患者中79例(16.1%)发生BC。OW后多因素Logistic回归结果显示,FDP>10.65 mg/L、MELD评分>15分为术后BC发生的独立危险因素(均P10.65mg/L为BC发生的独立危险因素。

关键词：肝移植胆道并发症纤维蛋白(原)降解产物重叠加权

在线全文

学校读者我要写书评

暂无评论

中国共产党自我革命的时代特征

中南民族大学学报（人文社会科学版） 2023年第3期43卷 1-8,181页

作者：黄蓉生马欧阳西南大学马克思主义理论研究中心/马克思主义学院重庆400715

新时代以来,习近平总书记对党的自我革命作了大量论述,提出了一系列具有新的历史特点的新理念和新观点。“自我革命”是马克思主义理论中国化的最新成果,体现出鲜明的中国特色,彰显了马克思主义政党的革命本质性、党的自身建设的全面性... 详细信息

新时代以来,习近平总书记对党的自我革命作了大量论述,提出了一系列具有新的历史特点的新理念和新观点。“自我革命”是马克思主义理论中国化的最新成果,体现出鲜明的中国特色,彰显了马克思主义政党的革命本质性、党的自身建设的全面性、党的社会革命的引导性、党的事业发展需要的时代性等鲜明特征。深刻把握这些特征对于深入理解自我革命理论,将党的伟大事业不断推向前进,具有重要的现实价值和深远影响。

关键词：中国共产党自我革命社会革命时代特征

维普期刊数据库博看期刊

Adult metaplastic hutch diverticulum with robotic-assisted diverticulectomy and reconstruction:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2020年第20期8卷 4895-4901页

作者： Che H yang Yi s Lin Yen C ou Wei C Weng Li H huang Chin H Lu Chao Y Hsu Min C Tung Department of surgery Division of UrologyTungs’Taichung MetroHarbor HospitalTaichung City 435403Taiwan

BACKGRouND Hutch diverticulum arises from the compromised muscular development at the ureteral *** is a congenital disease and extremely rare in adult,only accounting for about 3%occurrence *** can be either symptomatic or asymptomatic,and relies on image tools for diagnosis and preoperative *** for surgery are dependent on the complications from the *** is about 10%among those with hutch diverticulum,and it still has chances turning into malignancy,especially urothelial cell *** sUMMARY A 27-year-old man was presented with frequently recurrent urinary tract infection for one year,and had suffered from intermittent right flank pain for 3 *** past medical histories were recorded *** obvious abnormalities on laboratory data and urine examination were *** ultrasound,right hydronephrosis was seen and an anatomical abnormality was observed on intravenous *** computed tomography urogram showed one diverticulum seated at superolateral side of right ureteral *** was done and biopsy results showed focal *** discussing with him,roboticassisted diverticulectomy with reconstruction was *** hydronephrosis was greatly improved after *** has completed his 1.5-year follow-ups,and no malignancies were seen from urine cytology and image of intravenous *** Robotic-assisted diverticulectomy and reconstruction to hutch diverticulum is a safe and efficient operation,providing several advantages over open and laparoscopic ones.

关键词： Diverticulum complications Urinary bladder abnormalities Diverticulum surgery Robotic surgical procedures methods Treatment outcome Case report

IFN-a production by human mononuclear cells infected with varicella-zoster virus through TLR9-dependent and-independent pathways

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2011年第2期8卷 181-188页

作者： Hong-Ren Yu Hsin-Chun huang Ho-Chang Kuo Jiunn-Ming sheen Chia-Yo ou Te-Yao Hsu Kuender D yang Department of Pediatrics Chang Gung Memorial Hospital-Kaohsiung Medical CenterGraduate Institute of Clinical Medical ScienceChang Gung University College of MedicineTaiwan Department of Obstetrics Chang Gung Memorial Hospital-Kaohsiung Medical CenterGraduate Institute of Clinical Medical ScienceChang Gung University College of MedicineTaiwan

Understanding the defense mechanisms of the host of an organism is important for infection *** previous studies,we demonstrated that interferon-a(IFN-a),but not IL-12,was produced by human peripheral blood mononuclear cells infected with varicella-zoster virus(VZV).Here,we investigated what kind of cell(s)and which signal molecule(s)are involved in IFN-a *** cell isolation and ELIsA,we found that plasmacytoid dendritic cells(pDCs)were responsible for IFN-a production during VZV *** also found that Toll-like receptor 9(TLR9)was involved in VZV-induced IFN-a production because inhibitory CpG oligodeoxynucleotide inhibited IFN-a ***-inactivated VZV-induced IFN-a production was lower than that of active VZV,indicating another TLR9-independent *** studies demonstrated that double-stranded RNA-dependent protein kinase,but not DNA-dependent protein kinase was involved in VZV-induced IFN-a ***,these results suggest that pDCs play an important role in IFN-a production during VZV infection through TLR9-dependent and-independent pathways.

关键词： IFN-a mononuclear cells plasmacytoid dendritic cell TLR9 varicella-zoster virus

Eight-year follow-up of locally advanced lymphoepithelioma-like carcinoma at upper urinary tract: A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2020年第19期8卷 4505-4511页

作者： Che H yang Wei C Weng Yi s Lin Li H huang Chin H Lu Chao Y Hsu Yen C ou Min C Tung Department of surgery Division of UrologyTungs'Taichung MetroHarbor HospitalTaichung City 435403Taiwan

BACKGRouND Urinary tract lymphoepithelioma-like carcinoma is rarely *** it is termed after lymphoepithelioma at the nasopharynx,it behaves more like high grade urothelial carcinoma by immunohistochemical *** published literatures focused on its rarity but few discussed results of long-term *** no available guidelines are applicable,we postulated that principles should be similar to that of urothelial carcinoma at urinary *** of now,this work features the longest follow-up of this cancer at the upper urinary *** sUMMARY A 63-year-old female had a chief complaint of intermittent left flank pain for 2 mo,along with accompanying symptoms including vomiting and body weight loss,about 7 kg over 2 *** data showed normocytic anemia,mildly poor renal function,and *** analysis showed mild *** tomography showed a 4.2-cm-width irregular mass over left renal pelvic and enlarged lymph node at the left renal ***-body bone scan was negative of active bone *** from ureteroscopy showed urothelial *** from laparoscopic nephroureterectomy with bladder cuff resection showed lymphoepithelioma-like carcinoma with muscular invasion(pT3).she took adjuvant chemotherapies of 2 cycles and full courses of radiation *** recurrence was observed with designed investigative *** Locally advanced urinary tract lymphoepithelioma-like carcinoma could benefit from nephroureterectomy and bladder cuff excision in terms of recurrence-free survival.

关键词： Urologic neoplasms pathology Kidney pelvis Tomography X-ray computed Carcinoma mortality Kidney neoplasms mortality Case report